| UniProt ID | KNL1_HUMAN | |
|---|---|---|
| UniProt AC | Q8NG31 | |
| Protein Name | Kinetochore scaffold 1 | |
| Gene Name | KNL1 {ECO:0000312|HGNC:HGNC:24054} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 2342 | |
| Subcellular Localization | Nucleus. Chromosome, centromere, kinetochore. Weakly expressed in interphase nuclei. Expression increases from prophase to late anaphase, but greatly diminishes from the telophase and cytokinesis to early G1 phase of cell cycle. | |
| Protein Description | Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.. | |
| Protein Sequence | MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVSFADTIKVFQTESHMKIVRKSEMEGCSAMVPSQLQLLPPGFKRFSCLSLPETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCRQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 24 | Phosphorylation | RPVRRRHSSILKPPR CCHHHHCHHCCCCCC | 23927012 | ||
| 25 | Phosphorylation | PVRRRHSSILKPPRS CHHHHCHHCCCCCCC | 23401153 | ||
| 28 | Ubiquitination | RRHSSILKPPRSPLQ HHCHHCCCCCCCCHH | 29967540 | ||
| 32 | Phosphorylation | SILKPPRSPLQDLRG HCCCCCCCCHHCCCC | 29255136 | ||
| 47 | Phosphorylation | GNERVQESNALRNKK CCHHHHHHHHHCCCC | 23917254 | ||
| 56 | Phosphorylation | ALRNKKNSRRVSFAD HHCCCCCCCCCCHHH | 23882029 | ||
| 60 | Phosphorylation | KKNSRRVSFADTIKV CCCCCCCCHHHHHHE | 25159151 | ||
| 64 | Phosphorylation | RRVSFADTIKVFQTE CCCCHHHHHHEEECC | 23927012 | ||
| 65 | Ubiquitination | RVSFADTIKVFQTES CCCHHHHHHEEECCC | 22505724 | ||
| 68 | Ubiquitination | FADTIKVFQTESHMK HHHHHHEEECCCCCE | 22505724 | ||
| 75 | Acetylation | FQTESHMKIVRKSEM EECCCCCEEEHHHHH | 25953088 | ||
| 75 | Ubiquitination | FQTESHMKIVRKSEM EECCCCCEEEHHHHH | 29967540 | ||
| 79 | Ubiquitination | SHMKIVRKSEMEGCS CCCEEEHHHHHCCCC | 21963094 | ||
| 80 | Phosphorylation | HMKIVRKSEMEGCSA CCEEEHHHHHCCCCC | - | ||
| 104 | Phosphorylation | PPGFKRFSCLSLPET CCCCCEEEEEECCCC | 29083192 | ||
| 107 | Phosphorylation | FKRFSCLSLPETETG CCEEEEEECCCCCCC | 29083192 | ||
| 111 | Phosphorylation | SCLSLPETETGENLL EEEECCCCCCCCCEE | 29083192 | ||
| 124 | Ubiquitination | LLLIQNKKLEDNYCE EEEECCCCCCCCCEE | 29967540 | ||
| 128 | Ubiquitination | QNKKLEDNYCEITGM CCCCCCCCCEECCCC | 22817900 | ||
| 129 | Phosphorylation | NKKLEDNYCEITGMN CCCCCCCCEECCCCH | 28796482 | ||
| 133 | Phosphorylation | EDNYCEITGMNTLLS CCCCEECCCCHHHHH | 28796482 | ||
| 150 | Ubiquitination | IHTQMQQKEFSIIEH CCHHHHHHCCCHHHH | 29967540 | ||
| 153 | Phosphorylation | QMQQKEFSIIEHTRE HHHHHCCCHHHHHHH | 23312004 | ||
| 158 | O-linked_Glycosylation | EFSIIEHTRERKHAN CCCHHHHHHHHCCCC | 30379171 | ||
| 173 | Ubiquitination | DQTVIFSDENQMDLT CCEEEEECCCCCCCC | 22505724 | ||
| 173 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 173 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 173 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 176 | Ubiquitination | VIFSDENQMDLTSSH EEEECCCCCCCCCCC | 22505724 | ||
| 176 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 176 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 176 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 187 | Ubiquitination | TSSHTVMITKGLLDN CCCCEEEEECCCCCC | 21963094 | ||
| 187 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 187 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 187 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 197 | Phosphorylation | GLLDNPISEKSTKID CCCCCCCCCCCCCCC | 26270265 | ||
| 197 | Ubiquitination | GLLDNPISEKSTKID CCCCCCCCCCCCCCC | 29967540 | ||
| 199 | Acetylation | LDNPISEKSTKIDTT CCCCCCCCCCCCCCH | 25953088 | ||
| 199 | Ubiquitination | LDNPISEKSTKIDTT CCCCCCCCCCCCCCH | 21906983 | ||
| 199 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 200 | Phosphorylation | DNPISEKSTKIDTTS CCCCCCCCCCCCCHH | 26270265 | ||
| 201 | Phosphorylation | NPISEKSTKIDTTSF CCCCCCCCCCCCHHH | 26270265 | ||
| 202 | Sumoylation | PISEKSTKIDTTSFL CCCCCCCCCCCHHHH | - | ||
| 202 | Sumoylation | PISEKSTKIDTTSFL CCCCCCCCCCCHHHH | - | ||
| 202 | Ubiquitination | PISEKSTKIDTTSFL CCCCCCCCCCCHHHH | 21906983 | ||
| 202 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 206 | Phosphorylation | KSTKIDTTSFLANLK CCCCCCCHHHHHHCC | 28555341 | ||
| 207 | Phosphorylation | STKIDTTSFLANLKL CCCCCCHHHHHHCCC | 28555341 | ||
| 212 | Ubiquitination | TTSFLANLKLHTEDS CHHHHHHCCCCCCCC | 29967540 | ||
| 213 | Acetylation | TSFLANLKLHTEDSR HHHHHHCCCCCCCCC | 7683783 | ||
| 213 | Ubiquitination | TSFLANLKLHTEDSR HHHHHHCCCCCCCCC | 21906983 | ||
| 213 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 220 | Ubiquitination | KLHTEDSRMKKEVNF CCCCCCCCCHHEECC | 29967540 | ||
| 223 | Acetylation | TEDSRMKKEVNFSVD CCCCCCHHEECCCCC | 7683791 | ||
| 223 | Ubiquitination | TEDSRMKKEVNFSVD CCCCCCHHEECCCCC | 29967540 | ||
| 226 | Ubiquitination | SRMKKEVNFSVDQNT CCCHHEECCCCCCCC | 29967540 | ||
| 234 | Phosphorylation | FSVDQNTSSENKIDF CCCCCCCCCCCCCCH | 28555341 | ||
| 236 | Ubiquitination | VDQNTSSENKIDFND CCCCCCCCCCCCHHH | 22817900 | ||
| 238 | Ubiquitination | QNTSSENKIDFNDFI CCCCCCCCCCHHHHH | 29967540 | ||
| 246 | Ubiquitination | IDFNDFIKRLKTGKC CCHHHHHHHHHCCCC | 29967540 | ||
| 252 | Sumoylation | IKRLKTGKCSAFPDV HHHHHCCCCCCCCCC | - | ||
| 252 | Sumoylation | IKRLKTGKCSAFPDV HHHHHCCCCCCCCCC | - | ||
| 252 | Ubiquitination | IKRLKTGKCSAFPDV HHHHHCCCCCCCCCC | 29967540 | ||
| 253 | Ubiquitination | KRLKTGKCSAFPDVP HHHHCCCCCCCCCCC | 23503661 | ||
| 257 | Ubiquitination | TGKCSAFPDVPDKEN CCCCCCCCCCCCCCC | 23503661 | ||
| 259 | Ubiquitination | KCSAFPDVPDKENFE CCCCCCCCCCCCCCC | 23503661 | ||
| 262 | Ubiquitination | AFPDVPDKENFEIPI CCCCCCCCCCCCCCC | 22817900 | ||
| 262 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 262 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 262 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 270 | Phosphorylation | ENFEIPIYSKEPNSA CCCCCCCEECCCCCC | 25159151 | ||
| 271 | Phosphorylation | NFEIPIYSKEPNSAS CCCCCCEECCCCCCC | 25627689 | ||
| 272 | Ubiquitination | FEIPIYSKEPNSASS CCCCCEECCCCCCCC | 29967540 | ||
| 277 | Ubiquitination | YSKEPNSASSTHQMH EECCCCCCCCCEEEE | 29967540 | ||
| 280 | Phosphorylation | EPNSASSTHQMHVSL CCCCCCCCEEEEEEE | 28555341 | ||
| 288 | Sumoylation | HQMHVSLKEDENNSN EEEEEEEECCCCCCC | - | ||
| 288 | Ubiquitination | HQMHVSLKEDENNSN EEEEEEEECCCCCCC | 21906983 | ||
| 288 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 294 | Phosphorylation | LKEDENNSNITRLFR EECCCCCCCCHHHEE | 25159151 | ||
| 303 | Ubiquitination | ITRLFREKDDGMNFT CHHHEEECCCCCCCC | 29967540 | ||
| 361 | Ubiquitination | QILPATGNFSEIENQ EEEECCCCHHHHHHH | 23503661 | ||
| 365 | Ubiquitination | ATGNFSEIENQTQNA CCCCHHHHHHHCCCC | 23503661 | ||
| 367 | Ubiquitination | GNFSEIENQTQNAMD CCHHHHHHHCCCCEE | 23503661 | ||
| 367 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 367 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 367 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 382 | Ubiquitination | VTTGYGTKASGNKTV CCCCCCCCCCCCCEE | 29967540 | ||
| 387 | Ubiquitination | GTKASGNKTVFKSKQ CCCCCCCCEEEECCC | 23503661 | ||
| 391 | Ubiquitination | SGNKTVFKSKQNTAF CCCCEEEECCCCCCC | 23503661 | ||
| 393 | Ubiquitination | NKTVFKSKQNTAFQD CCEEEECCCCCCCCC | 21906983 | ||
| 393 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 402 | Phosphorylation | NTAFQDLSINSADKI CCCCCCCCCCCCCEE | 21815630 | ||
| 405 | Phosphorylation | FQDLSINSADKIHIT CCCCCCCCCCEEEEE | 21815630 | ||
| 408 | Acetylation | LSINSADKIHITRSH CCCCCCCEEEEEHHH | 25953088 | ||
| 408 | Ubiquitination | LSINSADKIHITRSH CCCCCCCEEEEEHHH | 29967540 | ||
| 425 | Phosphorylation | GAETHIVSQTCNQDA CCEEEEEEECCCCCC | 28555341 | ||
| 438 | Phosphorylation | DARILAMTPESIYSN CCEEEEECHHHHHCC | 21945579 | ||
| 441 | Phosphorylation | ILAMTPESIYSNPSI EEEECHHHHHCCCCC | 21945579 | ||
| 441 | Ubiquitination | ILAMTPESIYSNPSI EEEECHHHHHCCCCC | 29967540 | ||
| 443 | Phosphorylation | AMTPESIYSNPSIQG EECHHHHHCCCCCCC | 21945579 | ||
| 444 | Phosphorylation | MTPESIYSNPSIQGC ECHHHHHCCCCCCCC | 21945579 | ||
| 447 | Phosphorylation | ESIYSNPSIQGCKTV HHHHCCCCCCCCCEE | 21945579 | ||
| 450 | Ubiquitination | YSNPSIQGCKTVFYS HCCCCCCCCCEEEEC | 29967540 | ||
| 454 | Ubiquitination | SIQGCKTVFYSSCND CCCCCCEEEECCHHH | 29967540 | ||
| 456 | Phosphorylation | QGCKTVFYSSCNDAM CCCCEEEECCHHHHH | 23879269 | ||
| 457 | Phosphorylation | GCKTVFYSSCNDAME CCCEEEECCHHHHHH | 23879269 | ||
| 458 | Phosphorylation | CKTVFYSSCNDAMEM CCEEEECCHHHHHHH | 28985074 | ||
| 461 | Ubiquitination | VFYSSCNDAMEMTKC EEECCHHHHHHHHHH | 29967540 | ||
| 467 | Ubiquitination | NDAMEMTKCLSNMRE HHHHHHHHHHHHHHH | 29967540 | ||
| 476 | Ubiquitination | LSNMREEKNLLKHDS HHHHHHHHHHHHCCC | 29967540 | ||
| 480 | Ubiquitination | REEKNLLKHDSNYAK HHHHHHHHCCCCHHH | 29967540 | ||
| 487 | Ubiquitination | KHDSNYAKMYCNPDA HCCCCHHHHHCCHHH | 29967540 | ||
| 488 | Ubiquitination | HDSNYAKMYCNPDAM CCCCHHHHHCCHHHH | 29967540 | ||
| 489 | Phosphorylation | DSNYAKMYCNPDAMS CCCHHHHHCCHHHHH | 25159151 | ||
| 496 | Phosphorylation | YCNPDAMSSLTEKTI HCCHHHHHHCCCCEE | 27642862 | ||
| 497 | Phosphorylation | CNPDAMSSLTEKTIY CCHHHHHHCCCCEEE | 28555341 | ||
| 499 | Phosphorylation | PDAMSSLTEKTIYSG HHHHHHCCCCEEECC | - | ||
| 500 | Ubiquitination | DAMSSLTEKTIYSGE HHHHHCCCCEEECCC | 29967540 | ||
| 501 | Ubiquitination | AMSSLTEKTIYSGEE HHHHCCCCEEECCCC | - | ||
| 504 | Phosphorylation | SLTEKTIYSGEENMD HCCCCEEECCCCCCC | 27642862 | ||
| 505 | Phosphorylation | LTEKTIYSGEENMDI CCCCEEECCCCCCCC | 21815630 | ||
| 509 | Ubiquitination | TIYSGEENMDITKSH EEECCCCCCCCCCCC | 22505724 | ||
| 513 | Phosphorylation | GEENMDITKSHTVAI CCCCCCCCCCCEEEE | 19691289 | ||
| 514 | Ubiquitination | EENMDITKSHTVAID CCCCCCCCCCEEEEC | 29967540 | ||
| 515 | Phosphorylation | ENMDITKSHTVAIDN CCCCCCCCCEEEECC | 20860994 | ||
| 517 | Phosphorylation | MDITKSHTVAIDNQI CCCCCCCEEEECCCE | 18669648 | ||
| 523 | Ubiquitination | HTVAIDNQIFKQDQS CEEEECCCEECCCCC | 23503661 | ||
| 526 | Sumoylation | AIDNQIFKQDQSNVQ EECCCEECCCCCCCC | - | ||
| 526 | Sumoylation | AIDNQIFKQDQSNVQ EECCCEECCCCCCCC | - | ||
| 526 | Ubiquitination | AIDNQIFKQDQSNVQ EECCCEECCCCCCCC | 29967540 | ||
| 530 | Phosphorylation | QIFKQDQSNVQIAAA CEECCCCCCCCEEEC | 28555341 | ||
| 531 | Ubiquitination | IFKQDQSNVQIAAAP EECCCCCCCCEEECC | 29967540 | ||
| 532 | Ubiquitination | FKQDQSNVQIAAAPT ECCCCCCCCEEECCC | 22505724 | ||
| 534 | Ubiquitination | QDQSNVQIAAAPTPE CCCCCCCEEECCCCH | 22505724 | ||
| 539 | Phosphorylation | VQIAAAPTPEKEMML CCEEECCCCHHHHHH | 29255136 | ||
| 539 | Ubiquitination | VQIAAAPTPEKEMML CCEEECCCCHHHHHH | 22505724 | ||
| 544 | Ubiquitination | APTPEKEMMLQNLMT CCCCHHHHHHHHHHH | 29967540 | ||
| 551 | Phosphorylation | MMLQNLMTTSEDGKM HHHHHHHHCCCCCCC | 28555341 | ||
| 553 | Phosphorylation | LQNLMTTSEDGKMNV HHHHHHCCCCCCCCC | 28555341 | ||
| 557 | Ubiquitination | MTTSEDGKMNVNCNS HHCCCCCCCCCCCCC | 29967540 | ||
| 563 | Ubiquitination | GKMNVNCNSVPHVSK CCCCCCCCCCCCCCH | 29967540 | ||
| 564 | Phosphorylation | KMNVNCNSVPHVSKE CCCCCCCCCCCCCHH | 28555341 | ||
| 569 | Phosphorylation | CNSVPHVSKERIQQS CCCCCCCCHHHHHHH | 28555341 | ||
| 570 | Ubiquitination | NSVPHVSKERIQQSL CCCCCCCHHHHHHHH | 29967540 | ||
| 576 | Phosphorylation | SKERIQQSLSNPLSI CHHHHHHHHCCCCEE | 30108239 | ||
| 578 | Phosphorylation | ERIQQSLSNPLSISL HHHHHHHCCCCEEEC | 25159151 | ||
| 582 | Phosphorylation | QSLSNPLSISLTDRK HHHCCCCEEECCCCC | 30108239 | ||
| 584 | Phosphorylation | LSNPLSISLTDRKTE HCCCCEEECCCCCCH | 30108239 | ||
| 586 | Phosphorylation | NPLSISLTDRKTELL CCCEEECCCCCCHHH | 21815630 | ||
| 589 | Ubiquitination | SISLTDRKTELLSGE EEECCCCCCHHHCCC | 29967540 | ||
| 601 | Phosphorylation | SGENMDLTESHTSNL CCCCCCCCHHHCCCC | 19007248 | ||
| 617 | Ubiquitination | SQVPLAAYNLAPEST CCCCEEEEECCCCCC | 22505724 | ||
| 630 | Ubiquitination | STSESHSQSKSSSDE CCCCCCCCCCCCHHH | 22505724 | ||
| 631 | Ubiquitination | TSESHSQSKSSSDEC CCCCCCCCCCCHHHH | 23503661 | ||
| 631 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 631 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 631 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 633 | Phosphorylation | ESHSQSKSSSDECEE CCCCCCCCCHHHHHH | 25159151 | ||
| 634 | Phosphorylation | SHSQSKSSSDECEEI CCCCCCCCHHHHHHH | 21815630 | ||
| 635 | Phosphorylation | HSQSKSSSDECEEIT CCCCCCCHHHHHHHH | 22067460 | ||
| 640 | Ubiquitination | SSSDECEEITKSRNE CCHHHHHHHHHHCCC | 22505724 | ||
| 640 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 640 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 640 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 642 | Phosphorylation | SDECEEITKSRNEPF HHHHHHHHHHCCCCC | 28985074 | ||
| 642 | Ubiquitination | SDECEEITKSRNEPF HHHHHHHHHHCCCCC | 22505724 | ||
| 643 | Ubiquitination | DECEEITKSRNEPFQ HHHHHHHHHCCCCCC | 22505724 | ||
| 647 | Ubiquitination | EITKSRNEPFQRSDI HHHHHCCCCCCHHHH | 22505724 | ||
| 647 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 647 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 647 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 652 | Phosphorylation | RNEPFQRSDIIAKNS CCCCCCHHHHEECCC | 28555341 | ||
| 654 | Ubiquitination | EPFQRSDIIAKNSLT CCCCHHHHEECCCCC | 29967540 | ||
| 657 | Sumoylation | QRSDIIAKNSLTDTW CHHHHEECCCCCCCC | - | ||
| 657 | Sumoylation | QRSDIIAKNSLTDTW CHHHHEECCCCCCCC | - | ||
| 657 | Ubiquitination | QRSDIIAKNSLTDTW CHHHHEECCCCCCCC | 21906983 | ||
| 657 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 659 | Phosphorylation | SDIIAKNSLTDTWNK HHHEECCCCCCCCCC | 23403867 | ||
| 663 | Phosphorylation | AKNSLTDTWNKDKDW ECCCCCCCCCCCCCH | - | ||
| 666 | Ubiquitination | SLTDTWNKDKDWVLK CCCCCCCCCCCHHHH | 21906983 | ||
| 666 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 668 | Ubiquitination | TDTWNKDKDWVLKIL CCCCCCCCCHHHHHH | 22505724 | ||
| 673 | Ubiquitination | KDKDWVLKILPYLDK CCCCHHHHHHHCCCC | 21906983 | ||
| 673 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 677 | Phosphorylation | WVLKILPYLDKDSPQ HHHHHHHCCCCCCCC | 27174698 | ||
| 680 | Ubiquitination | KILPYLDKDSPQSAD HHHHCCCCCCCCCCC | 29967540 | ||
| 681 | Ubiquitination | ILPYLDKDSPQSADC HHHCCCCCCCCCCCC | 29967540 | ||
| 682 | Phosphorylation | LPYLDKDSPQSADCN HHCCCCCCCCCCCCC | 25159151 | ||
| 685 | Phosphorylation | LDKDSPQSADCNQEI CCCCCCCCCCCCHHH | 27174698 | ||
| 700 | Ubiquitination | ATSHNIVYCGGVLDK HHHCCEEEECCCCCC | 29967540 | ||
| 707 | Ubiquitination | YCGGVLDKQITNRNT EECCCCCCCCCCCCC | 29967540 | ||
| 711 | Ubiquitination | VLDKQITNRNTVSWE CCCCCCCCCCCCCHH | 29967540 | ||
| 716 | O-linked_Glycosylation | ITNRNTVSWEQSLFS CCCCCCCCHHHHHHC | 30379171 | ||
| 723 | Ubiquitination | SWEQSLFSTTKPLFS CHHHHHHCCCCCCCC | 29967540 | ||
| 726 | Ubiquitination | QSLFSTTKPLFSSGQ HHHHCCCCCCCCCCC | 29967540 | ||
| 731 | Ubiquitination | TTKPLFSSGQFSMKN CCCCCCCCCCEECCC | 29967540 | ||
| 735 | Phosphorylation | LFSSGQFSMKNHDTA CCCCCCEECCCCCCC | 26074081 | ||
| 737 | Ubiquitination | SSGQFSMKNHDTAIS CCCCEECCCCCCCCC | 29967540 | ||
| 738 | Ubiquitination | SGQFSMKNHDTAISS CCCEECCCCCCCCCH | 22505724 | ||
| 741 | Phosphorylation | FSMKNHDTAISSHTV EECCCCCCCCCHHHH | 28555341 | ||
| 749 | Ubiquitination | AISSHTVKSVLGQNS CCCHHHHHHHHCCCC | 29967540 | ||
| 750 | Phosphorylation | ISSHTVKSVLGQNSK CCHHHHHHHHCCCCH | - | ||
| 756 | Phosphorylation | KSVLGQNSKLAEPLR HHHHCCCCHHHHHHH | - | ||
| 757 | Acetylation | SVLGQNSKLAEPLRK HHHCCCCHHHHHHHH | 25953088 | ||
| 757 | Ubiquitination | SVLGQNSKLAEPLRK HHHCCCCHHHHHHHH | 29967540 | ||
| 764 | Ubiquitination | KLAEPLRKSLSNPTP HHHHHHHHHCCCCCC | 22505724 | ||
| 765 | Phosphorylation | LAEPLRKSLSNPTPD HHHHHHHHCCCCCCC | 25159151 | ||
| 767 | Phosphorylation | EPLRKSLSNPTPDYC HHHHHHCCCCCCCCC | 25159151 | ||
| 770 | Phosphorylation | RKSLSNPTPDYCHDK HHHCCCCCCCCCCCC | 28450419 | ||
| 773 | Phosphorylation | LSNPTPDYCHDKMII CCCCCCCCCCCCEEE | 29396449 | ||
| 777 | Ubiquitination | TPDYCHDKMIICSEE CCCCCCCCEEEECHH | - | ||
| 784 | Ubiquitination | KMIICSEEEQNMDLT CEEEECHHHHCCCCC | 29967540 | ||
| 793 | Phosphorylation | QNMDLTKSHTVVIGF HCCCCCCCCEEEEEE | 25627689 | ||
| 795 | Phosphorylation | MDLTKSHTVVIGFGP CCCCCCCEEEEEECH | 20860994 | ||
| 804 | Ubiquitination | VIGFGPSELQELGKT EEEECHHHHHHHHCC | 29967540 | ||
| 810 | Ubiquitination | SELQELGKTNLEHTT HHHHHHHCCCCCCCC | 29967540 | ||
| 811 | Phosphorylation | ELQELGKTNLEHTTG HHHHHHCCCCCCCCC | 28555341 | ||
| 815 | Ubiquitination | LGKTNLEHTTGQLTT HHCCCCCCCCCCCEE | 29967540 | ||
| 816 | Phosphorylation | GKTNLEHTTGQLTTM HCCCCCCCCCCCEEC | 28555341 | ||
| 817 | Phosphorylation | KTNLEHTTGQLTTMN CCCCCCCCCCCEECC | 28555341 | ||
| 819 | Ubiquitination | NLEHTTGQLTTMNRQ CCCCCCCCCEECCCE | 21963094 | ||
| 820 | Ubiquitination | LEHTTGQLTTMNRQI CCCCCCCCEECCCEE | 29967540 | ||
| 830 | Sumoylation | MNRQIAVKVEKCGKS CCCEEEEEEEHHCCC | - | ||
| 830 | Acetylation | MNRQIAVKVEKCGKS CCCEEEEEEEHHCCC | 23749302 | ||
| 830 | Sumoylation | MNRQIAVKVEKCGKS CCCEEEEEEEHHCCC | - | ||
| 830 | Ubiquitination | MNRQIAVKVEKCGKS CCCEEEEEEEHHCCC | 29967540 | ||
| 835 | Ubiquitination | AVKVEKCGKSPIEKS EEEEEHHCCCCCHHC | 29967540 | ||
| 837 | Phosphorylation | KVEKCGKSPIEKSGV EEEHHCCCCCHHCCC | 24719451 | ||
| 837 | Ubiquitination | KVEKCGKSPIEKSGV EEEHHCCCCCHHCCC | 29967540 | ||
| 841 | Acetylation | CGKSPIEKSGVLKSN HCCCCCHHCCCCCCC | 25953088 | ||
| 841 | Ubiquitination | CGKSPIEKSGVLKSN HCCCCCHHCCCCCCC | 29967540 | ||
| 846 | Ubiquitination | IEKSGVLKSNCIMDV CHHCCCCCCCCEEHH | 29967540 | ||
| 847 | Phosphorylation | EKSGVLKSNCIMDVL HHCCCCCCCCEEHHH | 20230923 | ||
| 858 | Phosphorylation | MDVLEDESVQKPKFP EHHHCCCCCCCCCCC | 25159151 | ||
| 860 | Ubiquitination | VLEDESVQKPKFPKE HHCCCCCCCCCCCHH | 29967540 | ||
| 861 | Acetylation | LEDESVQKPKFPKEK HCCCCCCCCCCCHHH | 25953088 | ||
| 861 | Ubiquitination | LEDESVQKPKFPKEK HCCCCCCCCCCCHHH | 29967540 | ||
| 863 | Ubiquitination | DESVQKPKFPKEKQN CCCCCCCCCCHHHCC | 29967540 | ||
| 872 | Ubiquitination | PKEKQNVKIWGRKSV CHHHCCCEEECCCCC | 29967540 | ||
| 875 | Phosphorylation | KQNVKIWGRKSVGGP HCCCEEECCCCCCCC | - | ||
| 878 | Phosphorylation | VKIWGRKSVGGPKID CEEECCCCCCCCCCC | 20860994 | ||
| 883 | Ubiquitination | RKSVGGPKIDKTIVF CCCCCCCCCCCEEEE | - | ||
| 886 | Acetylation | VGGPKIDKTIVFSED CCCCCCCCEEEECCC | 26051181 | ||
| 886 | Ubiquitination | VGGPKIDKTIVFSED CCCCCCCCEEEECCC | 29967540 | ||
| 887 | Phosphorylation | GGPKIDKTIVFSEDD CCCCCCCEEEECCCC | 28555341 | ||
| 890 | Ubiquitination | KIDKTIVFSEDDKND CCCCEEEECCCCCCC | 29967540 | ||
| 891 | Phosphorylation | IDKTIVFSEDDKNDM CCCEEEECCCCCCCC | 21815630 | ||
| 895 | Ubiquitination | IVFSEDDKNDMDITK EEECCCCCCCCCCCE | - | ||
| 901 | Phosphorylation | DKNDMDITKSYTIEI CCCCCCCCEEEEEEE | 28555341 | ||
| 903 | Phosphorylation | NDMDITKSYTIEINH CCCCCCEEEEEEECC | 23186163 | ||
| 904 | Phosphorylation | DMDITKSYTIEINHR CCCCCEEEEEEECCC | 23186163 | ||
| 905 | Phosphorylation | MDITKSYTIEINHRP CCCCEEEEEEECCCC | 20860994 | ||
| 916 | Acetylation | NHRPLLEKRDCHLVP CCCCCCCCCCCEEEE | 26051181 | ||
| 916 | Ubiquitination | NHRPLLEKRDCHLVP CCCCCCCCCCCEEEE | 29967540 | ||
| 927 | Ubiquitination | HLVPLAGTSETILYT EEEECCCCCCEEEEE | 21963094 | ||
| 935 | Ubiquitination | SETILYTCRQDDMEI CCEEEEEECCCCCEE | 23503661 | ||
| 938 | Ubiquitination | ILYTCRQDDMEITRS EEEEECCCCCEEECC | 23503661 | ||
| 943 | Phosphorylation | RQDDMEITRSHTTAL CCCCCEEECCCEEEE | - | ||
| 953 | Ubiquitination | HTTALECKTVSPDEI CEEEEEEEECCCCCC | 21963094 | ||
| 954 | Phosphorylation | TTALECKTVSPDEIT EEEEEEEECCCCCCC | 21712546 | ||
| 956 | Phosphorylation | ALECKTVSPDEITTR EEEEEECCCCCCCCC | 25159151 | ||
| 958 | Ubiquitination | ECKTVSPDEITTRPM EEEECCCCCCCCCCC | 23503661 | ||
| 961 | Phosphorylation | TVSPDEITTRPMDKT ECCCCCCCCCCCCCE | 24732914 | ||
| 962 | Phosphorylation | VSPDEITTRPMDKTV CCCCCCCCCCCCCEE | 24732914 | ||
| 981 | Ubiquitination | NHVELEMTESHTVFI CCEEEEECCCEEEEE | 29967540 | ||
| 1004 | Phosphorylation | DRPNFELSQRKSLGT CCCCCCHHHCCCCCC | 26074081 | ||
| 1007 | Ubiquitination | NFELSQRKSLGTPTV CCCHHHCCCCCCCEE | 29967540 | ||
| 1008 | Phosphorylation | FELSQRKSLGTPTVI CCHHHCCCCCCCEEE | 26074081 | ||
| 1011 | Phosphorylation | SQRKSLGTPTVICTP HHCCCCCCCEEEEEC | 28122231 | ||
| 1013 | Phosphorylation | RKSLGTPTVICTPTE CCCCCCCEEEEECCC | 27050516 | ||
| 1017 | Phosphorylation | GTPTVICTPTEESVF CCCEEEEECCCCCCC | 28731282 | ||
| 1019 | Phosphorylation | PTVICTPTEESVFFP CEEEEECCCCCCCCC | 26074081 | ||
| 1022 | Phosphorylation | ICTPTEESVFFPGNG EEECCCCCCCCCCCC | 26074081 | ||
| 1031 | Phosphorylation | FFPGNGESDRLVAND CCCCCCCCCEEEECC | 26074081 | ||
| 1038 | Ubiquitination | SDRLVANDSQLTPLE CCEEEECCCCCCCHH | 29967540 | ||
| 1039 | Phosphorylation | DRLVANDSQLTPLEE CEEEECCCCCCCHHH | 25159151 | ||
| 1042 | Phosphorylation | VANDSQLTPLEEWSN EECCCCCCCHHHHHC | 25159151 | ||
| 1043 | Ubiquitination | ANDSQLTPLEEWSNN ECCCCCCCHHHHHCC | 23503661 | ||
| 1046 | Ubiquitination | SQLTPLEEWSNNRGP CCCCCHHHHHCCCCC | 23503661 | ||
| 1046 (in isoform 2) | Ubiquitination | - | - | ||
| 1048 | Phosphorylation | LTPLEEWSNNRGPVE CCCHHHHHCCCCCCC | 26074081 | ||
| 1061 | Ubiquitination | VEVADNMELSKSATC CCHHCCCEECCCCCC | 23503661 | ||
| 1061 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 1061 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 1061 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 1063 | Phosphorylation | VADNMELSKSATCKN HHCCCEECCCCCCCC | 21815630 | ||
| 1064 | Ubiquitination | ADNMELSKSATCKNI HCCCEECCCCCCCCC | 29967540 | ||
| 1066 | Ubiquitination | NMELSKSATCKNIKD CCEECCCCCCCCCCC | 23503661 | ||
| 1069 | Acetylation | LSKSATCKNIKDVQS ECCCCCCCCCCCCCC | 25953088 | ||
| 1069 | Ubiquitination | LSKSATCKNIKDVQS ECCCCCCCCCCCCCC | 23503661 | ||
| 1072 | Sumoylation | SATCKNIKDVQSPGF CCCCCCCCCCCCCCC | - | ||
| 1072 | Sumoylation | SATCKNIKDVQSPGF CCCCCCCCCCCCCCC | - | ||
| 1072 | Ubiquitination | SATCKNIKDVQSPGF CCCCCCCCCCCCCCC | 23503661 | ||
| 1074 | Ubiquitination | TCKNIKDVQSPGFLN CCCCCCCCCCCCCCC | 29967540 | ||
| 1076 | Phosphorylation | KNIKDVQSPGFLNEP CCCCCCCCCCCCCCC | 29255136 | ||
| 1085 | Phosphorylation | GFLNEPLSSKSQRRK CCCCCCCCCHHHHHH | 25159151 | ||
| 1086 | Phosphorylation | FLNEPLSSKSQRRKS CCCCCCCCHHHHHHH | 21815630 | ||
| 1087 | Acetylation | LNEPLSSKSQRRKSL CCCCCCCHHHHHHHH | 25953088 | ||
| 1087 | Ubiquitination | LNEPLSSKSQRRKSL CCCCCCCHHHHHHHH | 21906983 | ||
| 1087 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 1088 | Phosphorylation | NEPLSSKSQRRKSLK CCCCCCHHHHHHHHC | 23917254 | ||
| 1092 | Ubiquitination | SSKSQRRKSLKLKND CCHHHHHHHHCCCCC | 23503661 | ||
| 1093 | Phosphorylation | SKSQRRKSLKLKNDK CHHHHHHHHCCCCCC | - | ||
| 1097 | Acetylation | RRKSLKLKNDKTIVF HHHHHCCCCCCEEEE | 25953088 | ||
| 1100 | Acetylation | SLKLKNDKTIVFSEN HHCCCCCCEEEECCC | 25953088 | ||
| 1100 | Ubiquitination | SLKLKNDKTIVFSEN HHCCCCCCEEEECCC | 29967540 | ||
| 1101 | Phosphorylation | LKLKNDKTIVFSENH HCCCCCCEEEECCCC | 30576142 | ||
| 1105 | Phosphorylation | NDKTIVFSENHKNDM CCCEEEECCCCCCCC | 30576142 | ||
| 1106 | Ubiquitination | DKTIVFSENHKNDMD CCEEEECCCCCCCCC | 22505724 | ||
| 1126 | Phosphorylation | MVEIDNESALEDKED EEEECCCHHHCCCCC | 23312004 | ||
| 1139 | Ubiquitination | EDFHLAGASKTILYS CCCCCCCCCCEEEEE | 29967540 | ||
| 1146 | Phosphorylation | ASKTILYSCGQDDME CCCEEEEECCCCCHH | 28555341 | ||
| 1155 | Phosphorylation | GQDDMEITRSHTTAL CCCCHHCCHHCCCCC | 20860994 | ||
| 1165 | Ubiquitination | HTTALECKTLLPNEI CCCCCHHHCCCCCCE | 29967540 | ||
| 1166 | Phosphorylation | TTALECKTLLPNEIA CCCCHHHCCCCCCEE | 20068231 | ||
| 1188 | Ubiquitination | VLFTDNYSDLEVTDS EEEECCCCCEEEECC | 29967540 | ||
| 1188 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 1188 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 1188 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 1195 | Ubiquitination | SDLEVTDSHTVFIDC CCEEEECCCEEEEEC | 29967540 | ||
| 1203 | Ubiquitination | HTVFIDCQATEKILE CEEEEECHHHHHHHH | 29967540 | ||
| 1214 | Acetylation | KILEENPKFGIGKGK HHHHHCCCCCCCCCC | 23236377 | ||
| 1214 | Ubiquitination | KILEENPKFGIGKGK HHHHHCCCCCCCCCC | 21906983 | ||
| 1214 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 1219 | Ubiquitination | NPKFGIGKGKNLGVS CCCCCCCCCCCCCCC | - | ||
| 1221 | Ubiquitination | KFGIGKGKNLGVSFP CCCCCCCCCCCCCCC | 29967540 | ||
| 1222 | Ubiquitination | FGIGKGKNLGVSFPK CCCCCCCCCCCCCCC | 29967540 | ||
| 1226 | Phosphorylation | KGKNLGVSFPKDNSC CCCCCCCCCCCCCHH | 28555341 | ||
| 1229 | Ubiquitination | NLGVSFPKDNSCVQE CCCCCCCCCCHHHHH | 29967540 | ||
| 1230 | Ubiquitination | LGVSFPKDNSCVQEI CCCCCCCCCHHHHHH | 29967540 | ||
| 1232 | Phosphorylation | VSFPKDNSCVQEIAE CCCCCCCHHHHHHHH | 19007248 | ||
| 1240 | Acetylation | CVQEIAEKQALAVGN HHHHHHHHHHHHHCC | 25953088 | ||
| 1240 | Ubiquitination | CVQEIAEKQALAVGN HHHHHHHHHHHHHCC | 22505724 | ||
| 1246 | Ubiquitination | EKQALAVGNKIVLHT HHHHHHHCCEEEEEH | 29967540 | ||
| 1248 | Ubiquitination | QALAVGNKIVLHTEQ HHHHHCCEEEEEHHH | 29967540 | ||
| 1253 | Phosphorylation | GNKIVLHTEQKQQLF CCEEEEEHHHHHHHH | 29978859 | ||
| 1255 | Ubiquitination | KIVLHTEQKQQLFAA EEEEEHHHHHHHHHH | 29967540 | ||
| 1256 | Ubiquitination | IVLHTEQKQQLFAAT EEEEHHHHHHHHHHC | 29967540 | ||
| 1259 | Ubiquitination | HTEQKQQLFAATNRT EHHHHHHHHHHCCCC | 22817900 | ||
| 1263 | Phosphorylation | KQQLFAATNRTTNEI HHHHHHHCCCCHHHH | 20068231 | ||
| 1266 | Phosphorylation | LFAATNRTTNEIIKF HHHHCCCCHHHHHHH | 24043423 | ||
| 1267 | Phosphorylation | FAATNRTTNEIIKFH HHHCCCCHHHHHHHH | 24043423 | ||
| 1269 | Ubiquitination | ATNRTTNEIIKFHSA HCCCCHHHHHHHHHH | 29967540 | ||
| 1272 | Ubiquitination | RTTNEIIKFHSAAMD CCHHHHHHHHHHHCC | 29967540 | ||
| 1281 | Ubiquitination | HSAAMDEKVIGKVVD HHHHCCHHHHHHHHH | 29967540 | ||
| 1285 | Acetylation | MDEKVIGKVVDQACT CCHHHHHHHHHHHCC | 26051181 | ||
| 1285 | Ubiquitination | MDEKVIGKVVDQACT CCHHHHHHHHHHHCC | 29967540 | ||
| 1292 | Phosphorylation | KVVDQACTLEKAQVE HHHHHHCCCCHHHHH | 22210691 | ||
| 1295 | Acetylation | DQACTLEKAQVESCQ HHHCCCCHHHHHHCC | 26051181 | ||
| 1295 | Ubiquitination | DQACTLEKAQVESCQ HHHCCCCHHHHHHCC | 29967540 | ||
| 1367 | Ubiquitination | PVQNDLAYANDFASE CCCCCEEHHCCHHHH | 22817900 | ||
| 1376 | Ubiquitination | NDFASEYYLESEGQP CCHHHHHEECCCCCC | 29967540 | ||
| 1387 | Ubiquitination | EGQPLSAPCPLLEKE CCCCCCCCCCCCCCH | 29967540 | ||
| 1393 | Ubiquitination | APCPLLEKEEVIQTS CCCCCCCCHHEEECC | 22817900 | ||
| 1393 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 1393 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 1393 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 1402 | Ubiquitination | EVIQTSTKGQLDCVI HEEECCCCCCCCEEE | 29967540 | ||
| 1413 | Ubiquitination | DCVITLHKDQDLIKD CEEEEEECCHHHHCC | 29967540 | ||
| 1415 | Ubiquitination | VITLHKDQDLIKDPR EEEEECCHHHHCCHH | 29967540 | ||
| 1415 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 1415 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 1415 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 1419 | Ubiquitination | HKDQDLIKDPRNLLA ECCHHHHCCHHHHHH | 21906983 | ||
| 1419 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 1427 | Ubiquitination | DPRNLLANQTLVYSQ CHHHHHHCCEEEEEC | 29967540 | ||
| 1429 | Phosphorylation | RNLLANQTLVYSQDL HHHHHCCEEEEECCH | 29978859 | ||
| 1432 | Phosphorylation | LANQTLVYSQDLGEM HHCCEEEEECCHHHC | 29978859 | ||
| 1433 | Phosphorylation | ANQTLVYSQDLGEMT HCCEEEEECCHHHCC | 29978859 | ||
| 1440 | Phosphorylation | SQDLGEMTKLNSKRV ECCHHHCCCCCCEEC | 29978859 | ||
| 1441 | Ubiquitination | QDLGEMTKLNSKRVS CCHHHCCCCCCEECE | 21906983 | ||
| 1441 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 1448 | Phosphorylation | KLNSKRVSFKLPKDQ CCCCEECEEECCHHH | 29496963 | ||
| 1450 | Ubiquitination | NSKRVSFKLPKDQMK CCEECEEECCHHHEE | - | ||
| 1453 | Ubiquitination | RVSFKLPKDQMKVYV ECEEECCHHHEEEEE | 29967540 | ||
| 1454 | Ubiquitination | VSFKLPKDQMKVYVD CEEECCHHHEEEEEE | 29967540 | ||
| 1455 | Ubiquitination | SFKLPKDQMKVYVDD EEECCHHHEEEEEEE | 29967540 | ||
| 1457 | Ubiquitination | KLPKDQMKVYVDDIY ECCHHHEEEEEEEEE | - | ||
| 1459 | Phosphorylation | PKDQMKVYVDDIYVI CHHHEEEEEEEEEEE | 27642862 | ||
| 1462 | Ubiquitination | QMKVYVDDIYVIPQP HEEEEEEEEEEECCC | 29967540 | ||
| 1464 | Phosphorylation | KVYVDDIYVIPQPHF EEEEEEEEEECCCCC | 28796482 | ||
| 1469 | Ubiquitination | DIYVIPQPHFSTDQP EEEEECCCCCCCCCC | 29967540 | ||
| 1469 (in isoform 2) | Ubiquitination | - | 21906983 | ||
| 1469 (in isoform 3) | Ubiquitination | - | 21906983 | ||
| 1469 (in isoform 4) | Ubiquitination | - | 21906983 | ||
| 1473 | Ubiquitination | IPQPHFSTDQPPLPK ECCCCCCCCCCCCCC | 29967540 | ||
| 1480 | Ubiquitination | TDQPPLPKKGQSSIN CCCCCCCCCCCCCCC | 29967540 | ||
| 1481 | Ubiquitination | DQPPLPKKGQSSINK CCCCCCCCCCCCCCH | 29967540 | ||
| 1485 | Phosphorylation | LPKKGQSSINKEEVI CCCCCCCCCCHHHEE | 28555341 | ||
| 1488 | Ubiquitination | KGQSSINKEEVILSK CCCCCCCHHHEEEEC | 29967540 | ||
| 1489 | Ubiquitination | GQSSINKEEVILSKA CCCCCCHHHEEEECC | 29967540 | ||
| 1491 | Ubiquitination | SSINKEEVILSKAGN CCCCHHHEEEECCCC | 29967540 | ||
| 1494 | Phosphorylation | NKEEVILSKAGNKSL CHHHEEEECCCCCCE | - | ||
| 1495 | Ubiquitination | KEEVILSKAGNKSLN HHHEEEECCCCCCEE | 2190698 | ||
| 1495 (in isoform 1) | Ubiquitination | - | 21906983 | ||
| 1499 | Ubiquitination | ILSKAGNKSLNIIEN EEECCCCCCEEEEEC | 29967540 | ||
| 1500 | Phosphorylation | LSKAGNKSLNIIENS EECCCCCCEEEEECC | 28555341 | ||
| 1504 | Ubiquitination | GNKSLNIIENSSAPI CCCCEEEEECCCCCC | 29967540 | ||
| 1508 | Ubiquitination | LNIIENSSAPICENK EEEEECCCCCCCCCC | 29967540 | ||
| 1515 | Sumoylation | SAPICENKPKILNSE CCCCCCCCCCCCCCH | - | ||
| 1515 | Sumoylation | SAPICENKPKILNSE CCCCCCCCCCCCCCH | - | ||
| 1515 | Ubiquitination | SAPICENKPKILNSE CCCCCCCCCCCCCCH | 29967540 | ||
| 1517 | Ubiquitination | PICENKPKILNSEEW CCCCCCCCCCCCHHH | 29967540 | ||
| 1530 | Acetylation | EWFAAACKKELKENI HHHHHHHHHHHHHHH | 25953088 | ||
| 1530 | Ubiquitination | EWFAAACKKELKENI HHHHHHHHHHHHHHH | 29967540 | ||
| 1531 | Ubiquitination | WFAAACKKELKENIQ HHHHHHHHHHHHHHC | - | ||
| 1534 | Ubiquitination | AACKKELKENIQTTN HHHHHHHHHHHCCCC | 29967540 | ||
| 1542 | Phosphorylation | ENIQTTNYNTALDFH HHHCCCCCCHHHEEC | 29759185 | ||
| 1558 | Ubiquitination | NSDVTKQVIQTHVNA CCHHHHHHHHHHCCC | 29967540 | ||
| 1584 | Ubiquitination | VPCFHSIKPNLNNLN CCCCCCCCCCCCCCC | 29967540 | ||
| 1616 | Ubiquitination | PEQLLELGNKAHNDM CHHHHHHCHHHCCCC | 29967540 | ||
| 1642 | Ubiquitination | NIISSNAKDSRDEEN EEECCCCCCCCCCCH | 29967540 | ||
| 1652 | Phosphorylation | RDEENKKSHNGAETT CCCCHHCCCCCCCCC | - | ||
| 1660 | Phosphorylation | HNGAETTSLPPKTVF CCCCCCCCCCCCCCC | - | ||
| 1665 | Phosphorylation | TTSLPPKTVFKDKVR CCCCCCCCCCCCCCH | 30622161 | ||
| 1670 | Methylation | PKTVFKDKVRRCSLG CCCCCCCCCHHCEEE | 23644510 | ||
| 1675 | Phosphorylation | KDKVRRCSLGIFLPR CCCCHHCEEECCCCC | 23927012 | ||
| 1690 | Phosphorylation | LPNKRNCSVTGIDDL CCCCCCCCCCCCCCH | 25159151 | ||
| 1692 | Phosphorylation | NKRNCSVTGIDDLEQ CCCCCCCCCCCCHHH | 25159151 | ||
| 1692 | Ubiquitination | NKRNCSVTGIDDLEQ CCCCCCCCCCCCHHH | 29967540 | ||
| 1704 | Phosphorylation | LEQIPADTTDINHLE HHHCCCCCCCCCCCC | 26552605 | ||
| 1705 | Phosphorylation | EQIPADTTDINHLET HHCCCCCCCCCCCCC | 26552605 | ||
| 1712 | Phosphorylation | TDINHLETQPVSSKD CCCCCCCCCCCCCCC | 26074081 | ||
| 1716 | Phosphorylation | HLETQPVSSKDSGIG CCCCCCCCCCCCCCC | 26074081 | ||
| 1717 | Phosphorylation | LETQPVSSKDSGIGS CCCCCCCCCCCCCCH | 26074081 | ||
| 1718 | Ubiquitination | ETQPVSSKDSGIGSV CCCCCCCCCCCCCHH | 29967540 | ||
| 1720 | Phosphorylation | QPVSSKDSGIGSVAG CCCCCCCCCCCHHCC | 21815630 | ||
| 1724 | Phosphorylation | SKDSGIGSVAGKLNL CCCCCCCHHCCEECC | 26074081 | ||
| 1732 | Phosphorylation | VAGKLNLSPSQYINE HCCEECCCHHHHCCC | 25159151 | ||
| 1734 | Phosphorylation | GKLNLSPSQYINEEN CEECCCHHHHCCCCC | 28464451 | ||
| 1736 | Phosphorylation | LNLSPSQYINEENLP ECCCHHHHCCCCCCC | 29496963 | ||
| 1744 | Ubiquitination | INEENLPVYPDEINS CCCCCCCCCCCCCCC | 29967540 | ||
| 1745 | Phosphorylation | NEENLPVYPDEINSS CCCCCCCCCCCCCCC | 28102081 | ||
| 1751 | Phosphorylation | VYPDEINSSDSINIE CCCCCCCCCCCCCCC | 28787133 | ||
| 1752 | Phosphorylation | YPDEINSSDSINIET CCCCCCCCCCCCCCH | 28102081 | ||
| 1752 | Ubiquitination | YPDEINSSDSINIET CCCCCCCCCCCCCCH | 29967540 | ||
| 1754 | Phosphorylation | DEINSSDSINIETEE CCCCCCCCCCCCHHH | 28102081 | ||
| 1768 | Phosphorylation | EKALIETYQKEISPY HHHHHHHHHHHCCCC | 29214152 | ||
| 1770 | Ubiquitination | ALIETYQKEISPYEN HHHHHHHHHCCCCCC | 29967540 | ||
| 1773 | Phosphorylation | ETYQKEISPYENKMG HHHHHHCCCCCCCCC | 25159151 | ||
| 1775 | Phosphorylation | YQKEISPYENKMGKT HHHHCCCCCCCCCCC | 24732914 | ||
| 1778 | Ubiquitination | EISPYENKMGKTCNS HCCCCCCCCCCCCCH | 29967540 | ||
| 1804 | Ubiquitination | IHKEKKIRKNEIKFS HHHHHHHCCCCCCCC | 29967540 | ||
| 1812 | Ubiquitination | KNEIKFSDTTQDREI CCCCCCCCCCCCHHH | 29967540 | ||
| 1813 | Phosphorylation | NEIKFSDTTQDREIF CCCCCCCCCCCHHHH | 28555341 | ||
| 1814 | Phosphorylation | EIKFSDTTQDREIFD CCCCCCCCCCHHHHC | 30576142 | ||
| 1824 | Phosphorylation | REIFDHHTEEDIDKS HHHHCCCCHHHHCHH | 20860994 | ||
| 1829 | Ubiquitination | HHTEEDIDKSANSVL CCCHHHHCHHCHHEE | 29967540 | ||
| 1830 | Ubiquitination | HTEEDIDKSANSVLI CCHHHHCHHCHHEEE | 29967540 | ||
| 1831 | Phosphorylation | TEEDIDKSANSVLIK CHHHHCHHCHHEEEE | 22199227 | ||
| 1834 | Phosphorylation | DIDKSANSVLIKNLS HHCHHCHHEEEECCC | 22199227 | ||
| 1838 | Ubiquitination | SANSVLIKNLSRTPS HCHHEEEECCCCCCC | 29967540 | ||
| 1841 | Phosphorylation | SVLIKNLSRTPSSCS HEEEECCCCCCCCCC | 20860994 | ||
| 1843 | Phosphorylation | LIKNLSRTPSSCSSS EEECCCCCCCCCCCC | 28450419 | ||
| 1845 | Phosphorylation | KNLSRTPSSCSSSLD ECCCCCCCCCCCCCH | 25159151 | ||
| 1846 | Phosphorylation | NLSRTPSSCSSSLDS CCCCCCCCCCCCCHH | 28450419 | ||
| 1848 | Phosphorylation | SRTPSSCSSSLDSIK CCCCCCCCCCCHHHC | 28450419 | ||
| 1849 | Phosphorylation | RTPSSCSSSLDSIKA CCCCCCCCCCHHHCC | 28450419 | ||
| 1850 | Phosphorylation | TPSSCSSSLDSIKAD CCCCCCCCCHHHCCC | 28450419 | ||
| 1853 | Phosphorylation | SCSSSLDSIKADGTS CCCCCCHHHCCCCCC | 26552605 | ||
| 1855 | Ubiquitination | SSSLDSIKADGTSLD CCCCHHHCCCCCCCC | 29967540 | ||
| 1859 | Phosphorylation | DSIKADGTSLDFSTY HHHCCCCCCCCHHHH | 23186163 | ||
| 1860 | Phosphorylation | SIKADGTSLDFSTYR HHCCCCCCCCHHHHC | 21815630 | ||
| 1864 | Phosphorylation | DGTSLDFSTYRSSQM CCCCCCHHHHCHHHH | 23186163 | ||
| 1865 | Phosphorylation | GTSLDFSTYRSSQME CCCCCHHHHCHHHHH | 23186163 | ||
| 1866 | Phosphorylation | TSLDFSTYRSSQMES CCCCHHHHCHHHHHH | 23186163 | ||
| 1868 | Phosphorylation | LDFSTYRSSQMESQF CCHHHHCHHHHHHHH | 20860994 | ||
| 1869 | Phosphorylation | DFSTYRSSQMESQFL CHHHHCHHHHHHHHH | 20860994 | ||
| 1879 | Phosphorylation | ESQFLRDTICEESLR HHHHHHHHHCHHHHH | 19007248 | ||
| 1888 | Ubiquitination | CEESLREKLQDGRIT CHHHHHHHHHCCCEE | - | ||
| 1915 | Phosphorylation | LIQKPRQSNLPGNFT HCCCCCCCCCCCCCC | - | ||
| 1916 | Ubiquitination | IQKPRQSNLPGNFTV CCCCCCCCCCCCCCC | 29967540 | ||
| 1925 | Phosphorylation | PGNFTVNTPPTPEDL CCCCCCCCCCCHHHH | 22067460 | ||
| 1935 | Ubiquitination | TPEDLMLSQYVYRPK CHHHHHHHCEEECCC | 29967540 | ||
| 1942 | Ubiquitination | SQYVYRPKIQIYRED HCEEECCCEEEEHHH | 29967540 | ||
| 1943 | Ubiquitination | QYVYRPKIQIYREDC CEEECCCEEEEHHHH | 29967540 | ||
| 1950 | Ubiquitination | IQIYREDCEARRQKI EEEEHHHHHHHHHHH | 29967540 | ||
| 1955 | Ubiquitination | EDCEARRQKIEELKL HHHHHHHHHHHHHHC | 24816145 | ||
| 1961 | Ubiquitination | RQKIEELKLSASNQD HHHHHHHHCCCCCCC | 29967540 | ||
| 1969 | Ubiquitination | LSASNQDKLLVDINK CCCCCCCCEEEECCH | 29967540 | ||
| 1976 | Ubiquitination | KLLVDINKNLWEKMR CEEEECCHHHHHHHC | 29967540 | ||
| 1981 | Ubiquitination | INKNLWEKMRHCSDK CCHHHHHHHCCCCHH | 29967540 | ||
| 1983 | Ubiquitination | KNLWEKMRHCSDKEL HHHHHHHCCCCHHHH | 29967540 | ||
| 1986 | Phosphorylation | WEKMRHCSDKELKAF HHHHCCCCHHHHHHH | - | ||
| 1990 | Ubiquitination | RHCSDKELKAFGIYL CCCCHHHHHHHHHHH | 29967540 | ||
| 1996 | Phosphorylation | ELKAFGIYLNKIKSC HHHHHHHHHHHHHHH | 20068231 | ||
| 1996 | Ubiquitination | ELKAFGIYLNKIKSC HHHHHHHHHHHHHHH | 29967540 | ||
| 2001 | Acetylation | GIYLNKIKSCFTKMT HHHHHHHHHHCHHHC | 7823275 | ||
| 2007 | Ubiquitination | IKSCFTKMTKVFTHQ HHHHCHHHCEEEECC | 29967540 | ||
| 2009 | Ubiquitination | SCFTKMTKVFTHQGK HHCHHHCEEEECCCH | 29967540 | ||
| 2011 | Ubiquitination | FTKMTKVFTHQGKVA CHHHCEEEECCCHHH | 29967540 | ||
| 2016 | Acetylation | KVFTHQGKVALYGKL EEEECCCHHHHHHHH | 7823283 | ||
| 2016 | Ubiquitination | KVFTHQGKVALYGKL EEEECCCHHHHHHHH | 29967540 | ||
| 2017 | Ubiquitination | VFTHQGKVALYGKLV EEECCCHHHHHHHHH | 29967540 | ||
| 2021 | Ubiquitination | QGKVALYGKLVQSAQ CCHHHHHHHHHHHHH | 29967540 | ||
| 2022 | Ubiquitination | GKVALYGKLVQSAQN CHHHHHHHHHHHHHH | 29967540 | ||
| 2033 | Ubiquitination | SAQNEREKLQIKIDE HHHHHHHHHHHHHHH | 29967540 | ||
| 2037 | Ubiquitination | EREKLQIKIDEMDKI HHHHHHHHHHHHHHH | 29967540 | ||
| 2043 | Ubiquitination | IKIDEMDKILKKIDN HHHHHHHHHHHHHHH | 29967540 | ||
| 2047 | Ubiquitination | EMDKILKKIDNCLTE HHHHHHHHHHHHHHH | 29967540 | ||
| 2057 | Ubiquitination | NCLTEMETETKNLED HHHHHHHHHHCCCCH | 29967540 | ||
| 2063 | Ubiquitination | ETETKNLEDEEKNNP HHHHCCCCHHHHCCC | 24816145 | ||
| 2076 | Phosphorylation | NPVEEWDSEMRAAEK CCHHHHHHHHHHHHH | 22067460 | ||
| 2080 | Ubiquitination | EWDSEMRAAEKELEQ HHHHHHHHHHHHHHH | 29967540 | ||
| 2083 | Ubiquitination | SEMRAAEKELEQLKT HHHHHHHHHHHHHHH | 29967540 | ||
| 2089 | Sumoylation | EKELEQLKTEEEELQ HHHHHHHHHHHHHHH | - | ||
| 2089 | Ubiquitination | EKELEQLKTEEEELQ HHHHHHHHHHHHHHH | 24816145 | ||
| 2090 | Phosphorylation | KELEQLKTEEEELQR HHHHHHHHHHHHHHH | 20860994 | ||
| 2106 | Ubiquitination | LLELEVQKEQTLAQI HHHHHHHHHHHHHHH | 29967540 | ||
| 2118 | Ubiquitination | AQIDFMQKQRNRTEE HHHHHHHHHHHCHHH | - | ||
| 2188 | Ubiquitination | NFQSLLDEDQAPPSS CHHHHCCCCCCCCHH | 29967540 | ||
| 2214 | Ubiquitination | EEKESWKKTCTTQHQ HHHHHHHHHHCCHHH | 29967540 | ||
| 2247 | Ubiquitination | GEEIEYLKRWGPNYN HHHHHHHHHHCCCCC | - | ||
| 2270 | Phosphorylation | NELRLLFSSSAAFAK CEEEEEEECHHHHHH | 28122231 | ||
| 2271 | Phosphorylation | ELRLLFSSSAAFAKF EEEEEEECHHHHHHH | 28122231 | ||
| 2272 | Phosphorylation | LRLLFSSSAAFAKFE EEEEEECHHHHHHHH | 26437602 | ||
| 2298 | Ubiquitination | VPLPSTIQNHVGNTS CCCCHHHHHCCCCCC | 29967540 | ||
| 2302 | Ubiquitination | STIQNHVGNTSQDDI HHHHHCCCCCCHHHH | 29967540 | ||
| 2324 | Ubiquitination | PLENNYLKNVVKQIY CCCCCHHHHHHHHHH | 29967540 | ||
| 2328 | Ubiquitination | NYLKNVVKQIYQDLF CHHHHHHHHHHHHHH | 29967540 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KNL1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KNL1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NSL1_HUMAN | NSL1 | physical | 20231385 | |
| BUB1_HUMAN | BUB1 | physical | 17981135 | |
| BUB1B_HUMAN | BUB1B | physical | 17981135 | |
| ZWINT_HUMAN | ZWINT | physical | 21199919 | |
| NSL1_HUMAN | NSL1 | physical | 21199919 | |
| NDC80_HUMAN | NDC80 | physical | 21199919 | |
| BUB1_HUMAN | BUB1 | physical | 21199919 | |
| BUB1B_HUMAN | BUB1B | physical | 21199919 | |
| BUB1_HUMAN | BUB1 | physical | 20220147 | |
| BUB1B_HUMAN | BUB1B | physical | 20220147 | |
| CD97_HUMAN | CD97 | physical | 26496610 | |
| CO4A5_HUMAN | COL4A5 | physical | 26496610 | |
| PML_HUMAN | PML | physical | 26496610 | |
| NDC80_HUMAN | NDC80 | physical | 26496610 | |
| ZWINT_HUMAN | ZWINT | physical | 26496610 | |
| PMF1_HUMAN | PMF1 | physical | 26496610 | |
| NSL1_HUMAN | NSL1 | physical | 26496610 | |
| SPC25_HUMAN | SPC25 | physical | 26496610 | |
| MIS12_HUMAN | MIS12 | physical | 26496610 | |
| DSN1_HUMAN | DSN1 | physical | 26496610 | |
| NUF2_HUMAN | NUF2 | physical | 26496610 | |
| SPC24_HUMAN | SPC24 | physical | 26496610 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
