SDF2L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SDF2L_HUMAN
• UniProt AC: Q9HCN8
• Protein Name: Stromal cell-derived factor 2-like protein 1
• Gene Name: SDF2L1
• Organism: Homo sapiens (Human).
• Sequence Length: 221
• Subcellular Localization: Endoplasmic reticulum lumen .
• Protein Sequence: MWSAGRGGAAWPVLLGLLLALLVPGGGAAKTGAELVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRIRGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMPSANTHNTWKAMEGIFIKPSVEPSAGHDEL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	AELVTCGSVLKLLNT CEEEEHHHHHHHHCC	26.82	-
43	Acetylation	VTCGSVLKLLNTHHR EEHHHHHHHHCCCCC	49.09	26051181
55	Phosphorylation	HHRVRLHSHDIKYGS CCCEEEEECCCEECC	27.70	23909892
59	Acetylation	RLHSHDIKYGSGSGQ EEEECCCEECCCCCC	50.01	25038526
85	Methylation	ANSYWRIRGGSEGGC CCCCEEECCCCCCCC	34.54	115493463
88	Phosphorylation	YWRIRGGSEGGCPRG CEEECCCCCCCCCCC	35.57	-
94	Methylation	GSEGGCPRGSPVRCG CCCCCCCCCCCCCCC	63.40	115493469
96	Phosphorylation	EGGCPRGSPVRCGQA CCCCCCCCCCCCCCE	22.85	26329039
203	Sulfoxidation	THNTWKAMEGIFIKP CCCCHHHCCCEEECC	4.26	21406390
209	Acetylation	AMEGIFIKPSVEPSA HCCCEEECCCCCCCC	22.08	26051181
211	Phosphorylation	EGIFIKPSVEPSAGH CCEEECCCCCCCCCC	33.83	-
211	O-linked_Glycosylation	EGIFIKPSVEPSAGH CCEEECCCCCCCCCC	33.83	55831409
215	Phosphorylation	IKPSVEPSAGHDEL- ECCCCCCCCCCCCC-	33.12	23186163
293	Ubiquitination	------------------------------------------------------------------------------- -------------------------------------------------------------------------------		21890473
293	Ubiquitination	------------------------------------------------------------------------------- -------------------------------------------------------------------------------		21890473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SDF2L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SDF2L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SDF2L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRSF5_HUMAN	SRSF5	physical	22863883
DJB11_HUMAN	DNAJB11	physical	26186194
VWA1_HUMAN	VWA1	physical	26186194
EMC3_HUMAN	EMC3	physical	26186194
PDIA5_HUMAN	PDIA5	physical	26186194
EMC7_HUMAN	EMC7	physical	26186194
EMC10_HUMAN	EMC10	physical	26186194
VWA1_HUMAN	VWA1	physical	28514442
DJB11_HUMAN	DNAJB11	physical	28514442
EMC10_HUMAN	EMC10	physical	28514442
CLIC1_HUMAN	CLIC1	physical	28514442
TECT2_HUMAN	TCTN2	physical	27173435

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.