1A26_HUMAN - dbPTM
1A26_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID 1A26_HUMAN
UniProt AC P30450
Protein Name HLA class I histocompatibility antigen, A-26 alpha chain
Gene Name HLA-A
Organism Homo sapiens (Human).
Sequence Length 365
Subcellular Localization Membrane
Single-pass type I membrane protein.
Protein Description Involved in the presentation of foreign antigens to the immune system..
Protein Sequence MAVMAPRTLVLLLSGALALTQTWAGSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQEGPEYWDRNTRNVKAHSQTDRANLGTLRGYYNQSEDGSHTIQRMYGCDVGPDGRFLRGYQQDAYDGKDYIALNEDLRSWTAADMAAQITQRKWETAHEAEQWRAYLEGRCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWASVVVPSGQEQRYTCHVQHEGLPKPLTLRWEPSSQPTIPIVGIIAGLVLFGAVIAGAVVAAVMWRRKSSDRKGGSYSQAASSDSAQGSDMSLTACKV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
110N-linked_GlycosylationGTLRGYYNQSEDGSH
HHHEECEECCCCCCC		30.34UniProtKB CARBOHYD
200UbiquitinationRRYLENGKETLQRTD
HHHHHCCHHHHHCCC		60.1421906983
267UbiquitinationAGDGTFQKWASVVVP
CCCCCEEEEEEEEEC		40.3021906983
292UbiquitinationVQHEGLPKPLTLRWE
EEECCCCCCEEEECC		58.6721906983
340UbiquitinationRRKSSDRKGGSYSQA
HCCCCCCCCCCCCCC		73.0321906983
343PhosphorylationSSDRKGGSYSQAASS
CCCCCCCCCCCCCCC		30.2226657352
344PhosphorylationSDRKGGSYSQAASSD
CCCCCCCCCCCCCCC		14.2128450419
345PhosphorylationDRKGGSYSQAASSDS
CCCCCCCCCCCCCCC		18.2928450419
349PhosphorylationGSYSQAASSDSAQGS
CCCCCCCCCCCCCCC		37.3828450419
350PhosphorylationSYSQAASSDSAQGSD
CCCCCCCCCCCCCCC		30.7526657352
352PhosphorylationSQAASSDSAQGSDMS
CCCCCCCCCCCCCCC		25.1723401153
356PhosphorylationSSDSAQGSDMSLTAC
CCCCCCCCCCCCEEE		20.3323401153
359PhosphorylationSAQGSDMSLTACKV-
CCCCCCCCCEEECC-		27.7923401153
364UbiquitinationDMSLTACKV------
CCCCEEECC------		48.8121906983
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of 1A26_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of 1A26_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of 1A26_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UGGG1_HUMANUGGT1physical
17353931
CD8A_HUMANCD8Aphysical
9177355
CD8A_HUMANCD8Aphysical
10809759
COPB_HUMANCOPB1physical
11884415
COPG1_HUMANCOPG1physical
11884415
TPSN_HUMANTAPBPphysical
11884415
TAP1_HUMANTAP1physical
11884415
SYVN1_HUMANSYVN1physical
21245296
UB2J1_HUMANUBE2J1physical
21245296
DERL1_HUMANDERL1physical
21245296
PSMD2_HUMANPSMD2physical
21245296
MAGA4_HUMANMAGEA4physical
21815906
BAP31_HUMANBCAP31physical
17056546
B2MG_HUMANB2Mphysical
8805302
STAT3_HUMANSTAT3physical
21988832
GNAS3_HUMANGNASphysical
9914489
GNAS2_HUMANGNASphysical
9914489
ALEX_HUMANGNASphysical
9914489
GNAS1_HUMANGNASphysical
9914489
BAG6_HUMANBAG6physical
21636303
MEOX2_HUMANMEOX2physical
24722188
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of 1A26_HUMAN

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Related Literatures of Post-Translational Modification

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