| UniProt ID | DRS7B_HUMAN | |
|---|---|---|
| UniProt AC | Q6IAN0 | |
| Protein Name | Dehydrogenase/reductase SDR family member 7B | |
| Gene Name | DHRS7B | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 325 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass type II membrane protein. |
|
| Protein Description | Putative oxidoreductase.. | |
| Protein Sequence | MVSPATRKSLPKVKAMDFITSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARKERKSKNS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 70 | Ubiquitination | GLGKECAKVFYAAGA CCCHHHHHHHHHCCC | 44.53 | - | |
| 70 | Acetylation | GLGKECAKVFYAAGA CCCHHHHHHHHHCCC | 44.53 | 26051181 | |
| 150 | Phosphorylation | AGISYRGTIMDTTVD CCCCCCCEEEEEEEE | 12.25 | 26074081 | |
| 154 | Phosphorylation | YRGTIMDTTVDVDKR CCCEEEEEEEECCHH | 16.02 | 26074081 | |
| 155 | Phosphorylation | RGTIMDTTVDVDKRV CCEEEEEEEECCHHH | 15.50 | 26074081 | |
| 160 | Ubiquitination | DTTVDVDKRVMETNY EEEEECCHHHHCCCC | 46.90 | 21906983 | |
| 167 | Phosphorylation | KRVMETNYFGPVALT HHHHCCCCCCHHHHH | 19.82 | - | |
| 180 | Phosphorylation | LTKALLPSMIKRRQG HHHHHHHHHHHHCCC | 32.86 | - | |
| 183 | Ubiquitination | ALLPSMIKRRQGHIV HHHHHHHHHCCCEEE | 32.65 | 21890473 | |
| 183 | 2-Hydroxyisobutyrylation | ALLPSMIKRRQGHIV HHHHHHHHHCCCEEE | 32.65 | - | |
| 193 | Phosphorylation | QGHIVAISSIQGKMS CCEEEEEEEECCCCC | 16.20 | - | |
| 194 | Phosphorylation | GHIVAISSIQGKMSI CEEEEEEEECCCCCC | 16.90 | 24114839 | |
| 211 | Acetylation | RSAYAASKHATQAFF HHHHHHHHHHHHHHH | 32.31 | 25953088 | |
| 282 | Ubiquitination | DVLAAVGKKKKDVIL HHHHHCCCCCCCCHH | 55.62 | 21890473 | |
| 310 | Phosphorylation | LAPGLFFSLMASRAR HCHHHHHHHHHHHHH | 15.20 | - | |
| 314 | Phosphorylation | LFFSLMASRARKERK HHHHHHHHHHHHHHH | 16.71 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DRS7B_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DRS7B_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DRS7B_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A4_HUMAN | APP | physical | 21832049 | |
| RAB7A_HUMAN | RAB7A | physical | 26344197 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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