dbPTM

ZCC18_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZCC18_HUMAN
UniProt AC	P0CG32
Protein Name	Zinc finger CCHC domain-containing protein 18 {ECO:0000305}
Gene Name	ZCCHC18 {ECO:0000312\|HGNC:HGNC:32459}
Organism	Homo sapiens (Human).
Sequence Length	403
Subcellular Localization
Protein Description
Protein Sequence	MASITACVGNSRQQNAPLPPWAHSMLRSLGRSLCPLVVKMAERNMKLFSGRVVPAQGKETFENWLIQVNEVLPDWSMSEEEKLKRLMKTLRGPAREVMRLLQAANPNLSVADFLRAMKLVFGESESSVTAHGKFFNTLQAQGEKASLYVIRLEVQLQNAIQAGILAEKDANQTRLQQLLLGAELNRDLRFRLKHLLRMYANKQERLPNFLELIKMIREEEDWDDAFIKRKRPKRSEPIMERAASPVAFQGAQPIAISSADCNCNVIEIDDTLDDSDEDVILVVSLYPSLTPTGAPPFRGRARPLDQVLVIDSPNNSGAQSLSTSGGSGYKNDGPGNIRRARKRKYTTRCSYCGEEGHSKETCDNESNKAQVFENLIITLQELTHTEERSKEVPGEHSDASEPQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASITACVGN -----CCCEEECCCC	21.12	27155012
49	Phosphorylation	ERNMKLFSGRVVPAQ HHCHHHHCCCEECCC	35.81	24719451
129	Phosphorylation	GESESSVTAHGKFFN CCCCCCEEECHHHHC	18.19	28509920
133	Ubiquitination	SSVTAHGKFFNTLQA CCEEECHHHHCHHHH	36.59	32015554
228	Ubiquitination	DWDDAFIKRKRPKRS CCCHHHHHCCCCCCC	45.47	22817900
230	Ubiquitination	DDAFIKRKRPKRSEP CHHHHHCCCCCCCCC	68.96	22817900
233	Ubiquitination	FIKRKRPKRSEPIME HHHCCCCCCCCCCHH	73.01	22817900
327	Phosphorylation	SLSTSGGSGYKNDGP CCCCCCCCCCCCCCC	42.34	23532336

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZCC18_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZCC18_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZCC18_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ZCC18_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZCC18_HUMAN

Related Literatures of Post-Translational Modification