dbPTM

NBEL2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NBEL2_HUMAN
UniProt AC	Q6ZNJ1
Protein Name	Neurobeachin-like protein 2
Gene Name	NBEAL2
Organism	Homo sapiens (Human).
Sequence Length	2754
Subcellular Localization	Endoplasmic reticulum .
Protein Description	Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis..
Protein Sequence	MAASERLYELWLLYYAQKDLGYLQQWLKAFVGAFKKSISLSSLEPRRPEEAGAEVPLLPLDELHVLAEQLHQADLEQALLLLKLFIILCRNLENIEAGRGQVLVPRVLALLTKLVAELKGCPPPQGRGTQLENVALHALLLCEGLFDPYQTWRRQRSGEVISSKEKSKYKFPPAALPQEFSAFFQESLQNADHLPPILLLRLIHLFCAVLAGGKENGQMAVSDGSVKGLLSVVRGWSRGPAPDPCLVPLALEALVGAVHVLHASRAPPRGPELRALLESYFHVLNADWPAGLSSGPEEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNNCFEHLTRLIQNSKLYLQSRAPPEGDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSDSPSAKEVFKERIGYPHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMCPPPPIRNEQPVLVLAQWLPSLPTAELRLFLAQRLRWLCDSCPASRATCVQAGLVGCLLETLSTGLALEARCQEQLLALLQALGRVSIRPMELRHLLRPRPGLDSEPGGAEAGKARHAGAVIRTLSGMARHQGPARALRYFDLTPSMAGIMVPPVQRWPGPGFTFHAWLCLHPMDTAPTPAPTRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYLTMSLPEVSFADSAWHCVAIVHVPGRRPFSQNLVHVYKDGHLVKTAPLRCPSLSEPFSSCCIGSAGYRTTTTTTGLPTPPVPATLAYTHPALTRSQSVPASTGLGWGSGLVAPLQEGSIDSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQATALRTLCTLGPNETAPFKPEGELHELSTRLLLHYSPQACKNNICLDLSPSHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLERVAAQPKEAEAGPAETHDLVGPELTSGHNTQGLVLPLGKSSEERMERNAVAAFLLMLRNFLQGHMVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSAQLLMEQVAAEGSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIVREHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLAREFLVRSLSADDVQVTQTMLSFLAATGDDGQAVGALDLLLALLHGSLVQESLAVFLLEPGNLEVLLALLVRPGSLPLLPDRVCKILRRLQQNERLPERSRQRLRLRECGLQGLVACLPEGTVSPQLCQGLYKLFLGADCLNLSDLLAVVQLSLQADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEAATAGSPPPSSPESPTSPKPAPPKPPTESPAEPSDVFLPSEAPCPDPDGFYHALSPFCTPFDLGLERSSVGSGNTAGGGGSSGTLTPASQPGTPSPLDGPRPFPAAPGRHSSSLSNVLEDGSLPEPTISGDDTSNTSNPQQTSEEELCNLLTNVLFSVTWRGVEGSDEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPVGVLASLTQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCSLLDRLGAWPHLANGTADLREMAQIGLRLVLGYILLEDPQLHAQAYVRLHMLLQTAVPARREEACYVLSKLEAALGRVLNTSSLESATDEAGSPLAAAAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFEDFQAFCATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMSSGQRRQWERAQSRRAFQELVLEPAQRRARLEGLRYTAVLKQQATQHSMALLHWGALWRQLASPCGAWALRDTPIPRWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKVSTPPELLQEDQLGEDELAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYDGSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFLNFPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYLSSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTNSPSIFQHLDELKAFFAEVVSDGVPLVLALVPHRQPHSFITQGSPDLLVTVSASGLLGTHSWLPYDRNISNYFSFSKDPTMGSHKTQRLLSGPWVPGSGVSGQALAVAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLHQGGLSVGLAPKPVQVLYGHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFPGPIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASLPLAEQPTALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSHVLVGLEDGKLIVVVAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPTEAR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAASERLYELW ----CCHHHHHHHHH	30.24	23401153
8	Phosphorylation	MAASERLYELWLLYY CCHHHHHHHHHHHHH	18.39	23401153
36	Ubiquitination	AFVGAFKKSISLSSL HHHHHHHHCCCCHHC	46.71	-
37	Phosphorylation	FVGAFKKSISLSSLE HHHHHHHCCCCHHCC	20.28	30108239
39	Phosphorylation	GAFKKSISLSSLEPR HHHHHCCCCHHCCCC	29.32	27499020
41	Phosphorylation	FKKSISLSSLEPRRP HHHCCCCHHCCCCCH	26.53	20860994
119	Ubiquitination	TKLVAELKGCPPPQG HHHHHHHHCCCCCCC	50.39	-
164	Ubiquitination	SGEVISSKEKSKYKF CCCCCCCCCCCCCCC	63.47	29967540
231	Phosphorylation	GSVKGLLSVVRGWSR CCHHHHHHHHHCCCC	24.49	-
237	Phosphorylation	LSVVRGWSRGPAPDP HHHHHCCCCCCCCCC	30.13	-
293	Phosphorylation	ADWPAGLSSGPEEAL CCCCCCCCCCHHHHH	32.12	28060719
294	Phosphorylation	DWPAGLSSGPEEALV CCCCCCCCCHHHHHH	64.51	28060719
302	Phosphorylation	GPEEALVTLRVSMLD CHHHHHHHHHHHHHH	15.08	28060719
344	Ubiquitination	TRLIQNSKLYLQSRA HHHHHCCCHHHHCCC	49.02	-
346 (in isoform 3)	Ubiquitination	-	13.36	21906983
371	Ubiquitination	LTEPDVQKVLDQDTD CCCCCHHHHHCCCCH	44.61	29967540
389	Phosphorylation	VHVVRVLTCIMSDSP HHHHHHHHHHHCCCC	9.34	22199227
393	Phosphorylation	RVLTCIMSDSPSAKE HHHHHHHCCCCCHHH	18.28	22199227
395	Phosphorylation	LTCIMSDSPSAKEVF HHHHHCCCCCHHHHH	17.28	22199227
397	Phosphorylation	CIMSDSPSAKEVFKE HHHCCCCCHHHHHHH	56.79	22199227
399	Ubiquitination	MSDSPSAKEVFKERI HCCCCCHHHHHHHHH	59.76	-
403	Ubiquitination	PSAKEVFKERIGYPH CCHHHHHHHHHCCHH	51.78	-
419 (in isoform 3)	Ubiquitination	-	34.82	21906983
448	Ubiquitination	CPPPPIRNEQPVLVL CCCCCCCCCCCEEEE	53.64	21963094
540	Ubiquitination	LRHLLRPRPGLDSEP HHHHHCCCCCCCCCC	31.33	23503661
554	Ubiquitination	PGGAEAGKARHAGAV CCCHHHHHHHHHHHH	49.66	-
652	Ubiquitination	FFTAAGTLVVAVCTR HHHHHCCEEEEEEEC	2.59	22505724
706	Ubiquitination	YKDGHLVKTAPLRCP EECCEEEECCCCCCC	45.38	29967540
720	Phosphorylation	PSLSEPFSSCCIGSA CCCCCCCCCCCCCCC	32.93	-
729	Phosphorylation	CCIGSAGYRTTTTTT CCCCCCCCCEECCCC	12.42	-
733	Phosphorylation	SAGYRTTTTTTGLPT CCCCCEECCCCCCCC	22.87	-
740	Phosphorylation	TTTTGLPTPPVPATL CCCCCCCCCCCCCEE	45.31	28348404
755	Phosphorylation	AYTHPALTRSQSVPA EECCCCCCCCCCCCC	30.31	26074081
757	Phosphorylation	THPALTRSQSVPAST CCCCCCCCCCCCCCC	22.90	30278072
759	Phosphorylation	PALTRSQSVPASTGL CCCCCCCCCCCCCCC	31.17	30278072
759	Ubiquitination	PALTRSQSVPASTGL CCCCCCCCCCCCCCC	31.17	23503661
763	Phosphorylation	RSQSVPASTGLGWGS CCCCCCCCCCCCCCC	19.55	23927012
764	Phosphorylation	SQSVPASTGLGWGSG CCCCCCCCCCCCCCC	38.23	30278072
770	Phosphorylation	STGLGWGSGLVAPLQ CCCCCCCCCCCCCCC	23.57	30278072
780	Phosphorylation	VAPLQEGSIDSTLAG CCCCCCCCCCCCCCC	23.59	23927012
783	Phosphorylation	LQEGSIDSTLAGTQD CCCCCCCCCCCCCCC	24.53	23927012
784	Phosphorylation	QEGSIDSTLAGTQDT CCCCCCCCCCCCCCC	19.51	23927012
788	Phosphorylation	IDSTLAGTQDTRWGS CCCCCCCCCCCCCCC	20.05	23927012
791	Phosphorylation	TLAGTQDTRWGSPTS CCCCCCCCCCCCCCC	20.64	23927012
816	Ubiquitination	FHEALQATALRTLCT HHHHHHHHHHHHHHH	17.17	23503661
833	Ubiquitination	PNETAPFKPEGELHE CCCCCCCCCCCCHHH	40.89	-
855	Ubiquitination	HYSPQACKNNICLDL HCCCHHHCCCEEEEC	56.92	-
863	Phosphorylation	NNICLDLSPSHGLDG CCEEEECCCCCCCCC	24.83	20873877
865	Phosphorylation	ICLDLSPSHGLDGRL EEEECCCCCCCCCCC	27.15	20873877
891	Ubiquitination	DVVNCVGGMGALLPL HHHHHCCHHHHHHHH	7.31	22505724
905	Ubiquitination	LLERVAAQPKEAEAG HHHHHHCCCCCCCCC	39.60	23503661
907	Ubiquitination	ERVAAQPKEAEAGPA HHHHCCCCCCCCCCC	58.43	29967540
912	Ubiquitination	QPKEAEAGPAETHDL CCCCCCCCCCCCCCC	17.29	23503661
932	Ubiquitination	TSGHNTQGLVLPLGK CCCCCCCCEEEECCC	18.73	23503661
939	Ubiquitination	GLVLPLGKSSEERME CEEEECCCCHHHHHH	59.50	23503661
939 (in isoform 2)	Ubiquitination	-	59.50	-
956	Ubiquitination	AVAAFLLMLRNFLQG HHHHHHHHHHHHHHC	3.43	22505724
1058	Ubiquitination	EHRQKLRKKYGVQFI HHHHHHHHHHCHHHH	61.86	-
1059	Ubiquitination	HRQKLRKKYGVQFIL HHHHHHHHHCHHHHH	40.58	-
1181	Ubiquitination	LLPDRVCKILRRLQQ CCHHHHHHHHHHHHH	41.75	-
1292	Phosphorylation	QDVLTRLYVLEAATA HHHHHHHHHHHHHHC	10.33	26074081
1298	Phosphorylation	LYVLEAATAGSPPPS HHHHHHHHCCCCCCC	38.30	26657352
1301	Phosphorylation	LEAATAGSPPPSSPE HHHHHCCCCCCCCCC	31.59	20058876
1305	Phosphorylation	TAGSPPPSSPESPTS HCCCCCCCCCCCCCC	65.38	26657352
1306	Phosphorylation	AGSPPPSSPESPTSP CCCCCCCCCCCCCCC	38.16	26657352
1309	Phosphorylation	PPPSSPESPTSPKPA CCCCCCCCCCCCCCC	36.54	26657352
1311	Phosphorylation	PSSPESPTSPKPAPP CCCCCCCCCCCCCCC	67.93	20873877
1312	Phosphorylation	SSPESPTSPKPAPPK CCCCCCCCCCCCCCC	34.02	20873877
1322	Phosphorylation	PAPPKPPTESPAEPS CCCCCCCCCCCCCCC	58.59	26074081
1324	Phosphorylation	PPKPPTESPAEPSDV CCCCCCCCCCCCCCC	31.71	26074081
1329	Phosphorylation	TESPAEPSDVFLPSE CCCCCCCCCCCCCCC	37.60	26074081
1350	Phosphorylation	DGFYHALSPFCTPFD CCCCCCCCCCCCCCC	19.40	26074081
1363	Phosphorylation	FDLGLERSSVGSGNT CCCCCCCCCCCCCCC	21.72	26074081
1364	Phosphorylation	DLGLERSSVGSGNTA CCCCCCCCCCCCCCC	36.40	26074081
1367	Phosphorylation	LERSSVGSGNTAGGG CCCCCCCCCCCCCCC	27.06	26074081
1370	Phosphorylation	SSVGSGNTAGGGGSS CCCCCCCCCCCCCCC	30.15	26074081
1376	Phosphorylation	NTAGGGGSSGTLTPA CCCCCCCCCCCCCCC	28.95	26074081
1377	Phosphorylation	TAGGGGSSGTLTPAS CCCCCCCCCCCCCCC	38.79	26074081
1379	Phosphorylation	GGGGSSGTLTPASQP CCCCCCCCCCCCCCC	29.43	26074081
1381	Phosphorylation	GGSSGTLTPASQPGT CCCCCCCCCCCCCCC	19.35	26074081
1384	Phosphorylation	SGTLTPASQPGTPSP CCCCCCCCCCCCCCC	37.80	26074081
1388	Phosphorylation	TPASQPGTPSPLDGP CCCCCCCCCCCCCCC	27.55	26074081
1390	Phosphorylation	ASQPGTPSPLDGPRP CCCCCCCCCCCCCCC	37.62	26074081
1410	Phosphorylation	GRHSSSLSNVLEDGS CCCCCCHHHHCCCCC	27.17	20058876
1444	Ubiquitination	TSEEELCNLLTNVLF CCHHHHHHHHHHHHH	51.19	21963094
1493	Ubiquitination	VRPPDCIKRSLLEMM CCCHHHHHHHHHHHH	42.12	-
1495	Phosphorylation	PPDCIKRSLLEMMLE CHHHHHHHHHHHHHH	32.10	20068231
1501	Ubiquitination	RSLLEMMLESALTDI HHHHHHHHHHHCCHH	4.55	21963094
1503	Phosphorylation	LLEMMLESALTDIKE HHHHHHHHHCCHHHH	25.31	20068231
1506	Phosphorylation	MMLESALTDIKEAPV HHHHHHCCHHHHCCH	35.08	24114839
1532 (in isoform 2)	Ubiquitination	-	38.15	-
1536	Ubiquitination	LLQDFLCAEGHGNQE HHHHHHHHCCCCCHH	28.14	23503661
1590	Ubiquitination	LVLGYILLEDPQLHA HHHHHHHHCCHHHHH	5.21	21963094
1593	Ubiquitination	GYILLEDPQLHAQAY HHHHHCCHHHHHHHH	29.29	23503661
1597	Ubiquitination	LEDPQLHAQAYVRLH HCCHHHHHHHHHHHH	12.32	21963094
1617	Ubiquitination	AVPARREEACYVLSK CCCCCHHHHHHHHHH	42.08	21963094
1624	Ubiquitination	EACYVLSKLEAALGR HHHHHHHHHHHHHHH	46.30	21963094
1635	Phosphorylation	ALGRVLNTSSLESAT HHHHHHCCCCHHHCC	18.61	29978859
1636	Phosphorylation	LGRVLNTSSLESATD HHHHHCCCCHHHCCC	31.67	29978859
1637	Phosphorylation	GRVLNTSSLESATDE HHHHCCCCHHHCCCC	33.83	29978859
1640	Phosphorylation	LNTSSLESATDEAGS HCCCCHHHCCCCCCC	41.59	26657352
1642	Phosphorylation	TSSLESATDEAGSPL CCCHHHCCCCCCCHH	43.59	29978859
1647	Phosphorylation	SATDEAGSPLAAAAA HCCCCCCCHHHHHHH	24.64	23401153
1648	Ubiquitination	ATDEAGSPLAAAAAA CCCCCCCHHHHHHHH	25.71	22505724
1682	Ubiquitination	AYEPLGLQWGLPSLP CCCCCCCCCCCCCCC	30.32	23503661
1689	Ubiquitination	QWGLPSLPPTNGSPT CCCCCCCCCCCCCCC	37.70	23503661
1705	Ubiquitination	FEDFQAFCATPEWRH HHHHHHHHCCHHHHH	4.64	22505724
1709	Ubiquitination	QAFCATPEWRHFIDK HHHHCCHHHHHHHHH	53.43	23503661
1716	Ubiquitination	EWRHFIDKQVQPTMS HHHHHHHHCCCCCCH	47.77	23503661
1721	Phosphorylation	IDKQVQPTMSQFEMD HHHCCCCCCHHHHHH	16.62	22210691
1723	Phosphorylation	KQVQPTMSQFEMDTY HCCCCCCHHHHHHHH	33.91	22210691
1745	Phosphorylation	SGFWNACYDMLMSSG HHHHHHHHHHHHHCC	11.28	25072903
1750	Phosphorylation	ACYDMLMSSGQRRQW HHHHHHHHCCCHHHH	27.62	25072903
1751	Phosphorylation	CYDMLMSSGQRRQWE HHHHHHHCCCHHHHH	25.61	25072903
1786	Phosphorylation	RLEGLRYTAVLKQQA HHHCHHHHHHHHHHH	12.12	24850871
1794	Ubiquitination	AVLKQQATQHSMALL HHHHHHHHHHHHHHH	23.60	22505724
1801	Ubiquitination	TQHSMALLHWGALWR HHHHHHHHHHHHHHH	2.01	22505724
1821	Ubiquitination	CGAWALRDTPIPRWK CCCHHCCCCCCCCCC	58.65	22505724
1828	Ubiquitination	DTPIPRWKLSSAETY CCCCCCCCCCCCHHH	39.51	22505724
1830	Phosphorylation	PIPRWKLSSAETYSR CCCCCCCCCCHHHHH	24.63	23312004
1831	Phosphorylation	IPRWKLSSAETYSRM CCCCCCCCCHHHHHH	40.33	23312004
1834	Phosphorylation	WKLSSAETYSRMRLK CCCCCCHHHHHHCEE	26.89	23312004
1835	Phosphorylation	KLSSAETYSRMRLKL CCCCCHHHHHHCEEE	5.93	25839225
1836	Phosphorylation	LSSAETYSRMRLKLV CCCCHHHHHHCEEEC	27.33	23312004
1841	Ubiquitination	TYSRMRLKLVPNHHF HHHHHCEEECCCCCC	36.75	29967540
1855	Phosphorylation	FDPHLEASALRDNLG CCHHHCHHHHHCCCC	20.61	20068231
1867	Phosphorylation	NLGEVPLTPTEEASL CCCCCCCCCCCCCCC	23.30	22617229
1869	Phosphorylation	GEVPLTPTEEASLPL CCCCCCCCCCCCCCE	41.02	30278072
1873	Phosphorylation	LTPTEEASLPLAVTK CCCCCCCCCCEEEEC	33.52	28102081
1879	Phosphorylation	ASLPLAVTKEAKVST CCCCEEEECCCCCCC	19.98	23403867
1880	Ubiquitination	SLPLAVTKEAKVSTP CCCEEEECCCCCCCC	49.42	29967540
1883	Ubiquitination	LAVTKEAKVSTPPEL EEEECCCCCCCCHHH	37.50	-
1883 (in isoform 2)	Ubiquitination	-	37.50	21906983
1886	Phosphorylation	TKEAKVSTPPELLQE ECCCCCCCCHHHHCC	45.94	-
1887	Ubiquitination	KEAKVSTPPELLQED CCCCCCCCHHHHCCC	16.92	22505724
1944	Ubiquitination	GLLEVTTQNVYFYDG CCEEEECCEEEEECC	28.20	22505724
1952	Ubiquitination	NVYFYDGSTERVETE EEEEECCCCCEEEEC	24.97	22505724
1956 (in isoform 2)	Ubiquitination	-	9.69	21906983
1958	Phosphorylation	GSTERVETEEGIGYD CCCCEEEECCCCCCC	36.16	30257219
2008	Phosphorylation	NFPCKVGTTPVSSPS CCCCCCCCCCCCCCC	30.80	29255136
2009	Phosphorylation	FPCKVGTTPVSSPSQ CCCCCCCCCCCCCCC	18.76	29255136
2009	Ubiquitination	FPCKVGTTPVSSPSQ CCCCCCCCCCCCCCC	18.76	22505724
2012	Phosphorylation	KVGTTPVSSPSQTPR CCCCCCCCCCCCCCC	37.42	21712546
2013	Phosphorylation	VGTTPVSSPSQTPRP CCCCCCCCCCCCCCC	28.89	26055452
2015	Phosphorylation	TTPVSSPSQTPRPQP CCCCCCCCCCCCCCC	48.94	30108239
2017	Phosphorylation	PVSSPSQTPRPQPGP CCCCCCCCCCCCCCC	26.13	30108239
2029	Phosphorylation	PGPIPPHTQVRNQVY CCCCCCCHHHHHHHH	34.24	28270605
2033	Ubiquitination	PPHTQVRNQVYSWLL CCCHHHHHHHHHHHH	36.49	22505724
2037	Phosphorylation	QVRNQVYSWLLRLRP HHHHHHHHHHHHCCC	16.64	24719451
2040	Ubiquitination	NQVYSWLLRLRPPSQ HHHHHHHHHCCCCCC	3.84	22505724
2049	Phosphorylation	LRPPSQGYLSSRSPQ CCCCCCCCCCCCCHH	8.86	24719451
2054	Phosphorylation	QGYLSSRSPQEMLRA CCCCCCCCHHHHHHH	32.65	-
2060	Ubiquitination	RSPQEMLRASGLTQK CCHHHHHHHCCCCHH	25.95	22505724
2067	Ubiquitination	RASGLTQKWVQREIS HHCCCCHHHHHHHHH	44.06	21906983
2067 (in isoform 1)	Ubiquitination	-	44.06	21906983
2098	Ubiquitination	NDLSQYPVFPWVLQD HHHHHCCCCCHHCCC	8.40	22505724
2105	Ubiquitination	VFPWVLQDYVSPTLD CCCHHCCCCCCCCCC	41.46	22505724
2124	Ubiquitination	AVFRDLSKPIGVVNP HHHCCCCCCCCCCCH	48.21	-
2125	Ubiquitination	VFRDLSKPIGVVNPK HHCCCCCCCCCCCHH	25.78	22505724
2132	Ubiquitination	PIGVVNPKHAQLVRE CCCCCCHHHHHHHHH	46.50	22505724
2140	Ubiquitination	HAQLVREKYESFEDP HHHHHHHHHHHCCCC	43.69	33845483
2140 (in isoform 1)	Ubiquitination	-	43.69	21906983
2143	Phosphorylation	LVREKYESFEDPAGT HHHHHHHHCCCCCCC	30.74	26657352
2153	Ubiquitination	DPAGTIDKFHYGTHY CCCCCCCEEECCCCC	30.14	-
2208	Phosphorylation	AWQARLESPADVKEL HHHHHCCCCHHHHHH	29.94	25850435
2321	Ubiquitination	VTDERERKALEGIIS CCCHHHHHHHHHHHH	53.20	-
2339	Ubiquitination	QTPCQLLKEPHPTRL CCHHHHCCCCCCCCC	77.21	29967540
2432	Phosphorylation	YDRNISNYFSFSKDP CCCCCCCCCCCCCCC	8.20	-
2434	Phosphorylation	RNISNYFSFSKDPTM CCCCCCCCCCCCCCC	20.46	24719451
2436	Phosphorylation	ISNYFSFSKDPTMGS CCCCCCCCCCCCCCC	34.64	19690332
2437	Ubiquitination	SNYFSFSKDPTMGSH CCCCCCCCCCCCCCC	66.76	-
2440	Phosphorylation	FSFSKDPTMGSHKTQ CCCCCCCCCCCCCHH	44.27	19690332
2445	Ubiquitination	DPTMGSHKTQRLLSG CCCCCCCCHHHCCCC	48.31	29967540
2472	Ubiquitination	LAVAPDGKLLFSGGH EEECCCCCEEEECCC	49.77	29967540
2697	Ubiquitination	IRSVAVTKERSHVLV EEEEEEECCCCEEEE	44.52	29967540
2724	Phosphorylation	GQPSEVRSSQFARKL CCCHHHHHHHHHHHH	33.40	23403867
2734	Phosphorylation	FARKLWRSSRRISQV HHHHHHHHHCCHHHC	19.33	26434552
2735	Phosphorylation	ARKLWRSSRRISQVS HHHHHHHHCCHHHCC	19.60	26434552
2739	Phosphorylation	WRSSRRISQVSSGET HHHHCCHHHCCCCCC	23.79	29255136
2742	Phosphorylation	SRRISQVSSGETEYN HCCHHHCCCCCCCCC	25.62	29255136
2743	Phosphorylation	RRISQVSSGETEYNP CCHHHCCCCCCCCCC	41.62	29255136
2746	Phosphorylation	SQVSSGETEYNPTEA HHCCCCCCCCCCCCC	47.50	29255136
2748	Phosphorylation	VSSGETEYNPTEAR- CCCCCCCCCCCCCC-	33.58	29255136
2751	Phosphorylation	GETEYNPTEAR---- CCCCCCCCCCC----	38.34	23927012

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NBEL2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NBEL2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NBEL2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of NBEL2_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
139090	Gray platelet syndrome (GPS)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NBEL2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-39; SER-757; THR-1867;SER-2739 AND SER-2742, AND MASS SPECTROMETRY.	19690332 [Abstract]
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