BBS10_HUMAN - dbPTM
BBS10_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BBS10_HUMAN
UniProt AC Q8TAM1
Protein Name Bardet-Biedl syndrome 10 protein
Gene Name BBS10
Organism Homo sapiens (Human).
Sequence Length 723
Subcellular Localization Cell projection, cilium . Located within the basal body of the primary cilium of differentiating preadipocytes.
Protein Description Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation..
Protein Sequence MLSSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLVLQKDFSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKHLHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQCEIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKMLRQLFKDLDLNYMTQTNDQNGTSSLFIYKNSGESYQAPDPGNGSIQRPYQDTVAENKDALEKTQTYLKVHSNLVIPDVELETYIPYSTPTLTPTDTFQTVETLTCLSLERNRLTDYYEPLLKNNSTAYSTRGNRIEISYENLQVTNITRKGSMLPVSCKLPNMGTSQSYLSSSMPAGCVLPVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTYIRAVHALQTNQPLVSSQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSEDEL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationSSMAAAGSVKAALQV
CHHHHHHHHHHHHHH		18.7329396449
40UbiquitinationGRQVLCTKPTGEVLL
CCEEEEECCCCCEEE		39.3233845483
135PhosphorylationFISQALLTFQTQILD
HHHHHHHHHHHHHHH		17.97-
148PhosphorylationLDGIMDQYLSRHFLS
HHHHHHHHHHHHHHH		11.46-
150PhosphorylationGIMDQYLSRHFLSIF
HHHHHHHHHHHHHHH		20.83-
161UbiquitinationLSIFSSAKERTLCRS
HHHHCCHHHHHHCHH		50.07-
299UbiquitinationEKTKAIMKHLHSQNV
HHHHHHHHHHHHCCC		36.5829967540
307UbiquitinationHLHSQNVKLLISSVK
HHHHCCCEEHHHCCC		45.1629967540
372UbiquitinationTALVKFCKPLILRSK
HHHHHHCHHHHHCCC		46.09-
378PhosphorylationCKPLILRSKRYVHLG
CHHHHHCCCCEEEEC		20.3122496350
432PhosphorylationFKDLDLNYMTQTNDQ
HHHCCCEEEEEECCC		14.6129978859
434PhosphorylationDLDLNYMTQTNDQNG
HCCCEEEEEECCCCC		23.1429978859
436PhosphorylationDLNYMTQTNDQNGTS
CCEEEEEECCCCCCE		31.4329978859
442PhosphorylationQTNDQNGTSSLFIYK
EECCCCCCEEEEEEE		23.7729978859
443PhosphorylationTNDQNGTSSLFIYKN
ECCCCCCEEEEEEEC		26.8329978859
444PhosphorylationNDQNGTSSLFIYKNS
CCCCCCEEEEEEECC		27.4329978859
448PhosphorylationGTSSLFIYKNSGESY
CCEEEEEEECCCCCE		9.2229978859
472PhosphorylationIQRPYQDTVAENKDA
CCCCCCCCCCCCHHH		13.1925921289
477UbiquitinationQDTVAENKDALEKTQ
CCCCCCCHHHHHHHH		35.5622817900
482UbiquitinationENKDALEKTQTYLKV
CCHHHHHHHHHHHHH		46.9421906983
483PhosphorylationNKDALEKTQTYLKVH
CHHHHHHHHHHHHHC		19.4425921289
536PhosphorylationERNRLTDYYEPLLKN
HHCCCCCCHHHHHCC		12.4228796482
537PhosphorylationRNRLTDYYEPLLKNN
HCCCCCCHHHHHCCC		17.5528796482
542UbiquitinationDYYEPLLKNNSTAYS
CCHHHHHCCCCCCCC		62.8623000965
558PhosphorylationRGNRIEISYENLQVT
CCCEEEEEEECEEEE		17.3824043423
559PhosphorylationGNRIEISYENLQVTN
CCEEEEEEECEEEEE		17.9427642862
613PhosphorylationFEILLHYYLLNYAKK
HHHHHHHHHHHHHHH		8.2526657352
617PhosphorylationLHYYLLNYAKKCHQS
HHHHHHHHHHHHCCC		21.5526657352
642AcetylationNALLGIPKVLYKSKT
HHHHCCCEEEEECCC		42.8412655657
646SumoylationGIPKVLYKSKTGKYS
CCCEEEEECCCCCCC		41.12-
646SumoylationGIPKVLYKSKTGKYS
CCCEEEEECCCCCCC		41.12-
658PhosphorylationKYSFPHTYIRAVHAL
CCCCCHHHHHHHHHH		5.8422817900
713UbiquitinationTVKRHPQKVHNQDSE
EECCCCCCCCCCCCC		50.3329967540
719PhosphorylationQKVHNQDSEDEL---
CCCCCCCCCCCC---		36.8623927012
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BBS10_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BBS10_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BBS10_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of BBS10_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
615987Bardet-Biedl syndrome 10 (BBS10)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BBS10_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory