CEND_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CEND_HUMAN
• UniProt AC: Q8N111
• Protein Name: Cell cycle exit and neuronal differentiation protein 1
• Gene Name: CEND1
• Organism: Homo sapiens (Human).
• Sequence Length: 149
• Subcellular Localization: Membrane ; Single-pass type IV membrane protein .
• Protein Description: Involved in neuronal differentiation..
• Protein Sequence: MESRGKSASSPKPDTKVPQVTTEAKVPPAADGKAPLTKPSKKEAPAEKQQPPAAPTTAPAKKTSAKADPALLNNHSNLKPAPTVPSSPDATPEPKGPGDGAEEDEAASGGPGGRGPWSCENFNPLLVAGGVAVAAIALILGVAFLVRKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MESRGKSASSPKPD -CCCCCCCCCCCCCC	35.89	23403867
9	Phosphorylation	ESRGKSASSPKPDTK CCCCCCCCCCCCCCC	55.02	23403867
10	Phosphorylation	SRGKSASSPKPDTKV CCCCCCCCCCCCCCC	36.34	23403867
15	Phosphorylation	ASSPKPDTKVPQVTT CCCCCCCCCCCCCEE	42.33	25072903
21	O-linked_Glycosylation	DTKVPQVTTEAKVPP CCCCCCCEECCCCCC	17.42	28657654
21	Phosphorylation	DTKVPQVTTEAKVPP CCCCCCCEECCCCCC	17.42	25072903
22	O-linked_Glycosylation	TKVPQVTTEAKVPPA CCCCCCEECCCCCCC	34.78	28657654
22	Phosphorylation	TKVPQVTTEAKVPPA CCCCCCEECCCCCCC	34.78	25072903
33	Ubiquitination	VPPAADGKAPLTKPS CCCCCCCCCCCCCCC	47.59	32142685
38	Ubiquitination	DGKAPLTKPSKKEAP CCCCCCCCCCCCCCC	55.78	32142685
61	Ubiquitination	APTTAPAKKTSAKAD CCCCCCCCCCCCCCC	56.37	32142685
76	Phosphorylation	PALLNNHSNLKPAPT HHHHCCCCCCCCCCC	46.08	27080861
83	Phosphorylation	SNLKPAPTVPSSPDA CCCCCCCCCCCCCCC	47.34	30108239
86	Phosphorylation	KPAPTVPSSPDATPE CCCCCCCCCCCCCCC	50.60	30177828
87	Phosphorylation	PAPTVPSSPDATPEP CCCCCCCCCCCCCCC	22.26	30177828
91	Phosphorylation	VPSSPDATPEPKGPG CCCCCCCCCCCCCCC	35.25	20886841
108	Phosphorylation	AEEDEAASGGPGGRG CHHHHHHHCCCCCCC	51.86	25332170

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CEND_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CEND_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CEND_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CEND_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.