ZN573_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN573_HUMAN
• UniProt AC: Q86YE8
• Protein Name: Zinc finger protein 573
• Gene Name: ZNF573
• Organism: Homo sapiens (Human).
• Sequence Length: 665
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MFPVLEPHQVGLIRSYNSKTMTCFQELVTFRDVAIDFSRQEWEYLDPNQRDLYRDVMLENYRNLVSLGGHSISKPVVVDLLERGKEPWMILREETQFTDLDLQCEIISYIEVPTYETDISSTQLQSIYKREKLYECKKCQKKFSSGYQLILHHRFHVIERPYECKECGKNFRSGYQLTLHQRFHTGEKPYECTECGKNFRSGYQLTVHQRFHTGEKTYECRQCGKAFIYASHIVQHERIHTGGKPYECQECGRAFSQGGHLRIHQRVHTGEKPYKCKECGKTFSRRSNLVEHGQFHTDEKPYICEKCGKAFRRGHQLTVHQRVHTGKKPYECKECGKGYTTASYFLLHQRIHKGGKPYECKECKKTFTLYRNLTRHQNIHTGEKLFECKQCGKTYTTGSKLFQHQKTHTGEKPYECKECGKAFSLYGYLKQHQKIHTGMKHFECKECKKTFTLYRNLTRHQNIHTGKKLFECQECGKAYSTGSNLIQHRKTHTGEKPYKCKECGKTFSLHGYLNQHQKIHTGMKPYECKVCRKTFTFYRNLTLHQSIHTDEKPFECKECGKTFRRSSHLTAHQSIHADKKPYECKECGKAFKMYGYLTQHQKIHTGGKPYECKECGKAFSRASNLVQHERIHTGEKPYVCKQCGKTFRYGSALKAHQRIHRSIKV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	QVGLIRSYNSKTMTC HEEEEEECCCCCEEH	26.23	-
17 (in isoform 3)	Phosphorylation	-	5.47	25693802
18 (in isoform 3)	Phosphorylation	-	29.34	25693802
165	Sumoylation	IERPYECKECGKNFR ECCCEEHHHCCCCCC	44.30	-
165	Sumoylation	IERPYECKECGKNFR ECCCEEHHHCCCCCC	44.30	-
229	Phosphorylation	QCGKAFIYASHIVQH CCCCEEEEEEEEEEC	36.75	-
231	Phosphorylation	GKAFIYASHIVQHER CCEEEEEEEEEECCC	1.52	-
269	Phosphorylation	RIHQRVHTGEKPYKC EEEEEEECCCCCEEC	5.15	29496963
272	Sumoylation	QRVHTGEKPYKCKEC EEEECCCCCEECCCC	28.07	-
272	Ubiquitination	QRVHTGEKPYKCKEC EEEECCCCCEECCCC	28.07	-
272	Sumoylation	QRVHTGEKPYKCKEC EEEECCCCCEECCCC	28.07	-
302	Phosphorylation	FHTDEKPYICEKCGK CCCCCCCEEHHHCCH	13.80	-
333	Sumoylation	GKKPYECKECGKGYT CCCCCCCCCCCCCCC	67.97	-
333	Sumoylation	GKKPYECKECGKGYT CCCCCCCCCCCCCCC	67.97	-
361	Sumoylation	GGKPYECKECKKTFT CCCCCCCCHHCCEEE	43.15	-
361	Sumoylation	GGKPYECKECKKTFT CCCCCCCCHHCCEEE	43.15	-
400	Sumoylation	KTYTTGSKLFQHQKT CEEECCCHHHCCCCC	25.97	-
400	Sumoylation	KTYTTGSKLFQHQKT CEEECCCHHHCCCCC	25.97	-
407	Phosphorylation	KLFQHQKTHTGEKPY HHHCCCCCCCCCCCC	26.96	27251275
409	Phosphorylation	FQHQKTHTGEKPYEC HCCCCCCCCCCCCCC	3.60	29496963
412	Ubiquitination	QKTHTGEKPYECKEC CCCCCCCCCCCCCHH	29.34	-
417	Sumoylation	GEKPYECKECGKAFS CCCCCCCCHHHHHHH	42.30	-
417	Sumoylation	GEKPYECKECGKAFS CCCCCCCCHHHHHHH	42.30	-
417	Ubiquitination	GEKPYECKECGKAFS CCCCCCCCHHHHHHH	42.30	-
434	Ubiquitination	GYLKQHQKIHTGMKH HHHHHHHHHCCCCCC	8.39	-
490	Ubiquitination	SNLIQHRKTHTGEKP CCHHCCCCCCCCCCC	22.96	-
491	Phosphorylation	NLIQHRKTHTGEKPY CHHCCCCCCCCCCCE	33.64	28348404
493	Phosphorylation	IQHRKTHTGEKPYKC HCCCCCCCCCCCEEC	6.19	24719451
496	Ubiquitination	RKTHTGEKPYKCKEC CCCCCCCCCEECCCC	29.81	-
557	Sumoylation	DEKPFECKECGKTFR CCCCCCCCCCCCEEC	28.75	-
557	Sumoylation	DEKPFECKECGKTFR CCCCCCCCCCCCEEC	28.75	-
585	Sumoylation	DKKPYECKECGKAFK CCCCCCHHHHHHHHH	51.61	-
585	Sumoylation	DKKPYECKECGKAFK CCCCCCHHHHHHHHH	51.61	-
596	Phosphorylation	KAFKMYGYLTQHQKI HHHHHHHHHHHCCEE	25.97	25884760
613	Sumoylation	GGKPYECKECGKAFS CCCCEECHHHHHHHH	44.67	-
613	Sumoylation	GGKPYECKECGKAFS CCCCEECHHHHHHHH	44.67	-
633	Phosphorylation	VQHERIHTGEKPYVC HCCCCCCCCCCCEEE	5.58	27732954

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN573_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN573_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN573_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ZN573_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.