| UniProt ID | HUMMR_HUMAN | |
|---|---|---|
| UniProt AC | Q8TDB4 | |
| Protein Name | Protein MGARP | |
| Gene Name | MGARP | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 240 | |
| Subcellular Localization |
Mitochondrion . Mitochondrion outer membrane Single-pass type IV membrane protein Cytoplasmic side . Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion. |
|
| Protein Description | Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity).. | |
| Protein Sequence | MYLRRAVSKTLALPLRAPPNPAPLGKDASLRRMSSNRFPGSSGSNMIYYLVVGVTVSAGGYYAYKTVTSDQAKHTEHKTNLKEKTKAEIHPFQGEKENVAETEKASSEAPEELIVEAEVVDAEESPSATVVVIKEASACPGHVEAAPETTAVSAETGPEVTDAAARETTEVNPETTPEVTNAALDEAVTIDNDKDTTKNETSDEYAELEEENSPAESESSAGDDLQEEASVGSEAASAQG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 35 | Phosphorylation | ASLRRMSSNRFPGSS HHHHHHCCCCCCCCC | 23.76 | - | |
| 41 | Phosphorylation | SSNRFPGSSGSNMIY CCCCCCCCCCCCCEE | 31.59 | 24275569 | |
| 44 | Phosphorylation | RFPGSSGSNMIYYLV CCCCCCCCCCEEEEE | 25.77 | - | |
| 49 | Phosphorylation | SGSNMIYYLVVGVTV CCCCCEEEEEEEEEE | 5.10 | - | |
| 57 | Phosphorylation | LVVGVTVSAGGYYAY EEEEEEEECCCEEEE | 16.30 | - | |
| 61 | Phosphorylation | VTVSAGGYYAYKTVT EEEECCCEEEEEEEC | 5.52 | - | |
| 62 | Phosphorylation | TVSAGGYYAYKTVTS EEECCCEEEEEEECC | 13.51 | - | |
| 64 | Phosphorylation | SAGGYYAYKTVTSDQ ECCCEEEEEEECCHH | 7.35 | - | |
| 66 | Phosphorylation | GGYYAYKTVTSDQAK CCEEEEEEECCHHHH | 19.15 | 24275569 | |
| 68 | Phosphorylation | YYAYKTVTSDQAKHT EEEEEEECCHHHHCC | 31.64 | 24275569 | |
| 69 | Phosphorylation | YAYKTVTSDQAKHTE EEEEEECCHHHHCCC | 24.32 | 24275569 | |
| 75 | Phosphorylation | TSDQAKHTEHKTNLK CCHHHHCCCCCCCHH | 38.79 | 24275569 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HUMMR_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HUMMR_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HUMMR_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of HUMMR_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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