CO9A3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CO9A3_HUMAN
• UniProt AC: Q14050
• Protein Name: Collagen alpha-3(IX) chain
• Gene Name: COL9A3
• Organism: Homo sapiens (Human).
• Sequence Length: 684
• Subcellular Localization: Secreted, extracellular space, extracellular matrix.
• Protein Description: Structural component of hyaline cartilage and vitreous of the eye..
• Protein Sequence: MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
288	Acetylation	DLGRPGPKGTPGVAG CCCCCCCCCCCCCCC	79.79	19807363
290	Phosphorylation	GRPGPKGTPGVAGPS CCCCCCCCCCCCCCC	24.01	-
297	Phosphorylation	TPGVAGPSGEPGMPG CCCCCCCCCCCCCCC	55.67	-
483	N-linked_Glycosylation	PKGTQGPNGTSGVQG CCCCCCCCCCCCCCC	73.52	UniProtKB CARBOHYD
534	Phosphorylation	ELCGGMISEQIAQLA HHHHHHHHHHHHHHH	17.98	-
552	Phosphorylation	RKPLAPGSIGRPGPA CCCCCCCCCCCCCCC	22.32	22210691
582	Phosphorylation	GARGPPGYRGPTGEL CCCCCCCCCCCCCCC	20.40	22210691
665	O-linked_Glycosylation	TPGICDTSACQGAVL CCCCCCCHHHCCCCC	17.50	OGP

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CO9A3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CO9A3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CO9A3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CO9A3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.