SLIK3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SLIK3_HUMAN
• UniProt AC: O94933
• Protein Name: SLIT and NTRK-like protein 3
• Gene Name: SLITRK3
• Organism: Homo sapiens (Human).
• Sequence Length: 977
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Description: Suppresses neurite outgrowth..
• Protein Sequence: MKPSIAEMLHRGRMLWIILLSTIALGWTTPIPLIEDSEEIDEPCFDPCYCEVKESLFHIHCDSKGFTNISQITEFWSRPFKLYLQRNSMRKLYTNSFLHLNNAVSINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLGLESLEYLQADYNVIKRIESGAFRNLSKLRVLILNDNLIPMLPTNLFKAVSLTHLDLRGNRLKVLFYRGMLDHIGRSLMELQLEENPWNCTCEIVQLKSWLERIPYTALVGDITCETPFHFHGKDLREIRKTELCPLLSDSEVEASLGIPHSSSSKENAWPTKPSSMLSSVHFTASSVEYKSSNKQPKPTKQPRTPRPPSTSQALYPGPNQPPIAPYQTRPPIPIICPTGCTCNLHINDLGLTVNCKERGFNNISELLPRPLNAKKLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLKSLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTLPTDAFAGTSLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENPWDCTCDLVPFKQWIETISSVSVVGDVLCRSPENLTHRDVRTIELEVLCPEMLHVAPAGESPAQPGDSHLIGAPTSASPYEFSPPGGPVPLSVLILSLLVLFFSAVFVAAGLFAYVLRRRRKKLPFRSKRQEGVDLTGIQMQCHRLFEDGGGGGGGSGGGGRPTLSSPEKAPPVGHVYEYIPHPVTQMCNNPIYKPREEEEVAVSSAQEAGSAERGGPGTQPPGMGEALLGSEQFAETPKENHSNYRTLLEKEKEWALAVSSSQLNTIVTVNHHHPHHPAVGGVSGVVGGTGGDLAGFRHHEKNGGVVLFPPGGGCGSGSMLLDRERPQPAPCTVGFVDCLYGTVPKLKELHVHPPGMQYPDLQQDARLKETLLFSAGKGFTDHQTQKSDYLELRAKLQTKPDYLEVLEKTTYRF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MKPSIAEMLHR ----CCCCHHHHHHH	28.98	27732954
68	N-linked_Glycosylation	CDSKGFTNISQITEF ECCCCCCCHHHHHHH	29.65	UniProtKB CARBOHYD
83	Phosphorylation	WSRPFKLYLQRNSMR HHCCHHHHHHHHHCC	11.02	-
88	Phosphorylation	KLYLQRNSMRKLYTN HHHHHHHHCCHHHHC	23.35	22496350
213	Phosphorylation	NRLKVLFYRGMLDHI CCEEEEEHHHHHHHH	11.33	22817900
278	Phosphorylation	DLREIRKTELCPLLS CHHHHHHHCCCCCCC	25.09	17929957
287	Phosphorylation	LCPLLSDSEVEASLG CCCCCCCCHHHHHHC	39.92	17929957
301	Phosphorylation	GIPHSSSSKENAWPT CCCCCCCCCCCCCCC	46.03	17929957
312	Phosphorylation	AWPTKPSSMLSSVHF CCCCCCHHHHHHEEE	32.06	-
315	Phosphorylation	TKPSSMLSSVHFTAS CCCHHHHHHEEEEEE	22.98	-
322	Phosphorylation	SSVHFTASSVEYKSS HHEEEEEECCEECCC	31.68	-
323	Phosphorylation	SVHFTASSVEYKSSN HEEEEEECCEECCCC	19.26	-
414	Phosphorylation	PLNAKKLYLSSNLIQ CCCHHHHHHCHHHHH	17.26	-
501	Phosphorylation	EIQPAAFSLMPNLKL HHCHHHHHHCCCCEE	21.02	29632367
579	Phosphorylation	PFKQWIETISSVSVV EHHHHHHHHHEEEEE	19.61	27732954
581	Phosphorylation	KQWIETISSVSVVGD HHHHHHHHEEEEEEH	31.91	27732954
582	Phosphorylation	QWIETISSVSVVGDV HHHHHHHEEEEEEHH	17.98	27732954
584	Phosphorylation	IETISSVSVVGDVLC HHHHHEEEEEEHHHC	17.03	27732954
596	N-linked_Glycosylation	VLCRSPENLTHRDVR HHCCCCCCCCCCCCC	54.33	UniProtKB CARBOHYD
853	Phosphorylation	VSGVVGGTGGDLAGF CCEECCCCCCCCCCC	31.87	-
904	Phosphorylation	VGFVDCLYGTVPKLK EEHHHHHCCCCCCHH	19.65	29978859
906	Phosphorylation	FVDCLYGTVPKLKEL HHHHHCCCCCCHHEE	21.78	29978859
951	Phosphorylation	TDHQTQKSDYLELRA CCCCCCCHHHHHHHH	22.97	30576142
953	Phosphorylation	HQTQKSDYLELRAKL CCCCCHHHHHHHHHH	14.79	30576142
966	Phosphorylation	KLQTKPDYLEVLEKT HHCCCCCHHHHHHHH	17.18	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SLIK3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SLIK3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SLIK3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SLIK3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.