dbPTM

KBTB7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KBTB7_HUMAN
UniProt AC	Q8WVZ9
Protein Name	Kelch repeat and BTB domain-containing protein 7
Gene Name	KBTBD7
Organism	Homo sapiens (Human).
Sequence Length	684
Subcellular Localization
Protein Description
Protein Sequence	MQSREDVPRSRRLASPRGGRRPKRISKPSVSAFFTGPEELKDTAHSAALLAQLKSFYDARLLCDVTIEVVTPGSGPGTGRLFSCNRNVLAAACPYFKSMFTGGMYESQQASVTMHDVDAESFEVLVDYCYTGRVSLSEANVQRLYAASDMLQLEYVREACASFLARRLDLTNCTAILKFADAFDHHKLRSQAQSYIAHNFKQLSRMGSIREETLADLTLAQLLAVLRLDSLDIESERTVCHVAVQWLEAAAKERGPSAAEVFKCVRWMHFTEEDQDYLEGLLTKPIVKKYCLDVIEGALQMRYGDLLYKSLVPVPNSSSSSSSSNSLVSAAENPPQRLGMCAKEMVIFFGHPRDPFLCYDPYSGDIYTMPSPLTSFAHTKTVTSSAVCVSPDHDIYLAAQPRKDLWVYKPAQNSWQQLADRLLCREGMDVAYLNGYIYILGGRDPITGVKLKEVECYSVQRNQWALVAPVPHSFYSFELIVVQNYLYAVNSKRMLCYDPSHNMWLNCASLKRSDFQEACVFNDEIYCICDIPVMKVYNPARGEWRRISNIPLDSETHNYQIVNHDQKLLLITSTTPQWKKNRVTVYEYDTREDQWINIGTMLGLLQFDSGFICLCARVYPSCLEPGQSFITEEDDARSESSTEWDLDGFSELDSESGSSSSFSDDEVWVQVAPQRNAQDQQGSL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MQSREDVPRS -----CCCHHCCCHH	36.02	27050516
15	Phosphorylation	PRSRRLASPRGGRRP CHHHHCCCCCCCCCC	21.52	30576142
26	Phosphorylation	GRRPKRISKPSVSAF CCCCCCCCCCCEEEC	42.41	30576142
29	Phosphorylation	PKRISKPSVSAFFTG CCCCCCCCEEECCCC	32.23	25159151
31	Phosphorylation	RISKPSVSAFFTGPE CCCCCCEEECCCCHH	24.56	22199227
35	Phosphorylation	PSVSAFFTGPEELKD CCEEECCCCHHHHHH	45.43	28102081
54	Ubiquitination	AALLAQLKSFYDARL HHHHHHHHHHHHHHH	26.83	21906983
162	Phosphorylation	YVREACASFLARRLD HHHHHHHHHHHHHCC	22.22	24719451
178	Ubiquitination	TNCTAILKFADAFDH CCHHHHHHHHHHCCH	32.18	22817900
187	Ubiquitination	ADAFDHHKLRSQAQS HHHCCHHHHHHHHHH	42.02	29967540
201	Ubiquitination	SYIAHNFKQLSRMGS HHHHHHHHHHHCCCC	56.50	21890473
252	Ubiquitination	QWLEAAAKERGPSAA HHHHHHHHHHCCCHH	43.12	-
263	Ubiquitination	PSAAEVFKCVRWMHF CCHHHHHHHHHHHCC	36.68	21963094
284	Ubiquitination	YLEGLLTKPIVKKYC HHHHHCCHHHHHHHH	32.49	21906983
288	Ubiquitination	LLTKPIVKKYCLDVI HCCHHHHHHHHHHHH	38.45	21890473
289	Ubiquitination	LTKPIVKKYCLDVIE CCHHHHHHHHHHHHH	30.24	22817900
290	Phosphorylation	TKPIVKKYCLDVIEG CHHHHHHHHHHHHHH	7.79	-
308	Phosphorylation	MRYGDLLYKSLVPVP HHHHCCEEEEEEECC	13.06	-
309	Ubiquitination	RYGDLLYKSLVPVPN HHHCCEEEEEEECCC	36.96	21906983
317	Phosphorylation	SLVPVPNSSSSSSSS EEEECCCCCCCCCCC	26.06	28555341
343	Ubiquitination	QRLGMCAKEMVIFFG HHHCCCCCEEEHHCC	41.22	21963094
403	Ubiquitination	YLAAQPRKDLWVYKP EEEECCCCCEEEEEC	64.95	22817900
409	Ubiquitination	RKDLWVYKPAQNSWQ CCCEEEEECCCCHHH	25.02	22817900
450	Ubiquitination	RDPITGVKLKEVECY CCCCCCCEEEEEEEE	56.01	21890473
452	Ubiquitination	PITGVKLKEVECYSV CCCCCEEEEEEEEEE	54.73	22817900
511	Ubiquitination	WLNCASLKRSDFQEA EEEHHHCCCCCHHHH	47.57	21963094
535	Ubiquitination	ICDIPVMKVYNPARG EEECCEEEEECCCCC	41.63	21963094
567	Ubiquitination	QIVNHDQKLLLITST EECCCCCEEEEEECC	47.35	-
579	Ubiquitination	TSTTPQWKKNRVTVY ECCCCCHHHCCEEEE	34.62	21890473
580	Ubiquitination	STTPQWKKNRVTVYE CCCCCHHHCCEEEEE	47.21	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KBTB7_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KBTB7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KBTB7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KBTB6_HUMAN	KBTBD6	physical	20562859
TEFM_HUMAN	TEFM	physical	20562859
PI4KB_HUMAN	PI4KB	physical	20562859
RBM26_HUMAN	RBM26	physical	20562859
ZO1_HUMAN	TJP1	physical	20562859
ZO2_HUMAN	TJP2	physical	20562859
RBFA_HUMAN	RBFA	physical	20562859
NSUN4_HUMAN	NSUN4	physical	20562859
IQGA1_HUMAN	IQGAP1	physical	20562859
FAN_HUMAN	NSMAF	physical	20562859
L2GL1_HUMAN	LLGL1	physical	20562859
CUL3_HUMAN	CUL3	physical	20562859
NU155_HUMAN	NUP155	physical	20562859
RPOM_HUMAN	POLRMT	physical	20562859
IF4B_HUMAN	EIF4B	physical	20562859
CCAR2_HUMAN	CCAR2	physical	20562859
TM160_HUMAN	TMEM160	physical	20562859
RB6I2_HUMAN	ERC1	physical	20562859
MTM1_HUMAN	MTM1	physical	20562859
OBSL1_HUMAN	OBSL1	physical	20562859
GBF1_HUMAN	GBF1	physical	20562859
TF3C1_HUMAN	GTF3C1	physical	20562859
BRSK2_HUMAN	BRSK2	physical	20562859
ZNF24_HUMAN	ZNF24	physical	20562859
VANG1_HUMAN	VANGL1	physical	20562859
IKBE_HUMAN	NFKBIE	physical	21988832
KBTB6_HUMAN	KBTBD6	physical	25684205
CUL3_HUMAN	CUL3	physical	25684205
RBX1_HUMAN	RBX1	physical	25684205
TIAM1_HUMAN	TIAM1	physical	25684205
MLP3B_HUMAN	MAP1LC3B	physical	25684205
GBRAP_HUMAN	GABARAP	physical	25684205
GBRL1_HUMAN	GABARAPL1	physical	25684205
GBRL2_HUMAN	GABARAPL2	physical	25684205
AL7A1_HUMAN	ALDH7A1	physical	26496610
PDIA3_HUMAN	PDIA3	physical	26496610
ZEP1_HUMAN	HIVEP1	physical	26496610
IDHP_HUMAN	IDH2	physical	26496610
RL34_HUMAN	RPL34	physical	26496610
TIAR_HUMAN	TIAL1	physical	26496610
ZSC21_HUMAN	ZSCAN21	physical	26496610
APBP2_HUMAN	APPBP2	physical	26496610
TCPE_HUMAN	CCT5	physical	26496610
CAMP2_HUMAN	CAMSAP2	physical	26496610
FBXL6_HUMAN	FBXL6	physical	26496610
SIR7_HUMAN	SIRT7	physical	26496610
THOC2_HUMAN	THOC2	physical	26496610
TEFM_HUMAN	TEFM	physical	26496610
KBTB6_HUMAN	KBTBD6	physical	26496610
LYSM2_HUMAN	LYSMD2	physical	26496610
NSUN4_HUMAN	NSUN4	physical	26496610
FA45A_HUMAN	FAM45A	physical	26496610
TEFM_HUMAN	TEFM	physical	28514442
CP2S1_HUMAN	CYP2S1	physical	28514442
RB6I2_HUMAN	ERC1	physical	28514442
KBTB8_HUMAN	KBTBD8	physical	28514442
MRM2_HUMAN	FTSJ2	physical	28514442
NSUN4_HUMAN	NSUN4	physical	28514442
KBTB6_HUMAN	KBTBD6	physical	28514442
TNIK_HUMAN	TNIK	physical	28514442
SNX33_HUMAN	SNX33	physical	28514442
MTEF4_HUMAN	MTERF4	physical	28514442
PI4KB_HUMAN	PI4KB	physical	28514442
FXL17_HUMAN	FBXL17	physical	28514442
LTBP1_HUMAN	LTBP1	physical	28514442
L2GL2_HUMAN	LLGL2	physical	28514442
NUMB_HUMAN	NUMB	physical	28514442
AGAP3_HUMAN	AGAP3	physical	28514442
ZN598_HUMAN	ZNF598	physical	28514442
SPT2_HUMAN	SPTY2D1	physical	28514442
KIF2A_HUMAN	KIF2A	physical	28514442
TRIPC_HUMAN	TRIP12	physical	28514442
SULF2_HUMAN	SULF2	physical	28514442
TM160_HUMAN	TMEM160	physical	28514442
NUMBL_HUMAN	NUMBL	physical	28514442
MAP7_HUMAN	MAP7	physical	28514442
ZO1_HUMAN	TJP1	physical	28514442
RT63_HUMAN	MRPL57	physical	28514442
ZBT21_HUMAN	ZBTB21	physical	28514442
MET15_HUMAN	METTL15	physical	28514442
KPCI_HUMAN	PRKCI	physical	28514442
ZO2_HUMAN	TJP2	physical	28514442
TPP2_HUMAN	TPP2	physical	28514442
TBC23_HUMAN	TBC1D23	physical	28514442
RPA49_HUMAN	POLR1E	physical	28514442
WDR44_HUMAN	WDR44	physical	28514442
ZC11A_HUMAN	ZC3H11A	physical	28514442
GTSE1_HUMAN	GTSE1	physical	28514442
CREG1_HUMAN	CREG1	physical	28514442
DCA13_HUMAN	DCAF13	physical	28514442
LMBL2_HUMAN	L3MBTL2	physical	28514442
POP7_HUMAN	POP7	physical	28514442
PI51A_HUMAN	PIP5K1A	physical	28514442
RT24_HUMAN	MRPS24	physical	28514442
H2A2B_HUMAN	HIST2H2AB	physical	28514442
RT26_HUMAN	MRPS26	physical	28514442
RM27_HUMAN	MRPL27	physical	28514442
L2GL1_HUMAN	LLGL1	physical	28514442
RT09_HUMAN	MRPS9	physical	28514442
PER1_HUMAN	PER1	physical	28514442
PHLB3_HUMAN	PHLDB3	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KBTB7_HUMAN

Related Literatures of Post-Translational Modification