ZSC21_HUMAN - dbPTM
ZSC21_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZSC21_HUMAN
UniProt AC Q9Y5A6
Protein Name Zinc finger and SCAN domain-containing protein 21
Gene Name ZSCAN21
Organism Homo sapiens (Human).
Sequence Length 473
Subcellular Localization Nucleus .
Protein Description Strong transcriptional activator..
Protein Sequence MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQCVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MMTKVLGMAP
-----CCCEECCCCC		19.3924043423
27SumoylationQVGPLMVKVEEKEEK
HCCCCEEEEECHHHC		29.9328112733
36AcetylationEEKEEKGKYLPSLEM
ECHHHCCCCCCHHHH		55.4725953088
37PhosphorylationEKEEKGKYLPSLEMF
CHHHCCCCCCHHHHH		32.3028509920
40PhosphorylationEKGKYLPSLEMFRQR
HCCCCCCHHHHHHHH		34.0728509920
64PhosphorylationPGPREALSQLRVLCC
CCHHHHHHHHHHHHH		33.9324719451
135PhosphorylationDEPGHQVSTPPNEQK
CCCCCCCCCCCCCCC		28.7323401153
136PhosphorylationEPGHQVSTPPNEQKP
CCCCCCCCCCCCCCC		43.8625159151
150PhosphorylationPVWEKISSSGTAKES
CHHHHHCCCCCCCCC		35.9423898821
151PhosphorylationVWEKISSSGTAKESP
HHHHHCCCCCCCCCC		33.1121712546
153PhosphorylationEKISSSGTAKESPSS
HHHCCCCCCCCCCCC		36.1824719451
157PhosphorylationSSGTAKESPSSMQPQ
CCCCCCCCCCCCCCC		29.4025850435
159PhosphorylationGTAKESPSSMQPQPL
CCCCCCCCCCCCCCC		47.9625850435
160PhosphorylationTAKESPSSMQPQPLE
CCCCCCCCCCCCCCC		25.4825850435
168PhosphorylationMQPQPLETSHKYESW
CCCCCCCCCCCCCCC		43.7623312004
169PhosphorylationQPQPLETSHKYESWG
CCCCCCCCCCCCCCC		14.4923312004
183PhosphorylationGPLYIQESGEEQEFA
CCEEEECCCCCCCCC		34.8229507054
202PhosphorylationKVRDCRLSTQHEESA
HHHHHCCHHCCCHHH		13.4829978859
203PhosphorylationVRDCRLSTQHEESAD
HHHHCCHHCCCHHHH		38.2429978859
208PhosphorylationLSTQHEESADEQKGS
CHHCCCHHHHHHCCC		37.7329255136
215PhosphorylationSADEQKGSEAEGLKG
HHHHHCCCHHCCCCC		40.4423879269
221SumoylationGSEAEGLKGDIISVI
CCHHCCCCCCEEEEE		66.4528112733
232SumoylationISVIIANKPEASLER
EEEEEECCCCHHHHH		34.9028112733
261AcetylationLQEAGSKKGRESVPT
HHHCCCCCCCCCCCC		65.9724886971
265PhosphorylationGSKKGRESVPTKPTP
CCCCCCCCCCCCCCC		31.8428555341
268PhosphorylationKGRESVPTKPTPGER
CCCCCCCCCCCCCCC		47.7228555341
269AcetylationGRESVPTKPTPGERR
CCCCCCCCCCCCCCE		40.6026051181
271PhosphorylationESVPTKPTPGERRYI
CCCCCCCCCCCCEEE		45.5428555341
275MethylationTKPTPGERRYICAEC
CCCCCCCCEEEECCC		42.4930761645
276MethylationKPTPGERRYICAECG
CCCCCCCEEEECCCC		22.3630761651
298PhosphorylationNLTKHRRTHTGEKPY
CCCCCCCCCCCCCCE		24.60-
300PhosphorylationTKHRRTHTGEKPYVC
CCCCCCCCCCCCEEE		46.56-
349MethylationGQSSDLLKHQRMHTE
CCCHHHHHHCCCCCC		45.01115978025
349SumoylationGQSSDLLKHQRMHTE
CCCHHHHHHCCCCCC		45.0128112733
374PhosphorylationKAFSGKGSLIRHYRI
HHCCCCCCEEEEEEE		24.90-
380MethylationGSLIRHYRIHTGEKP
CCEEEEEEEECCCCC		14.2124381755
383PhosphorylationIRHYRIHTGEKPYQC
EEEEEEECCCCCEEC		44.6728111955
396PhosphorylationQCNECGKSFSQHAGL
ECCCCCCCHHHHCCC		18.5328555341
405PhosphorylationSQHAGLSSHQRLHTG
HHHCCCCCCCCCCCC		28.7828555341
411PhosphorylationSSHQRLHTGEKPYKC
CCCCCCCCCCCCCCC		52.1827422710
414SumoylationQRLHTGEKPYKCKEC
CCCCCCCCCCCCCHH		55.80-
414UbiquitinationQRLHTGEKPYKCKEC
CCCCCCCCCCCCCHH		55.8021890473
414SumoylationQRLHTGEKPYKCKEC
CCCCCCCCCCCCCHH		55.80-
439PhosphorylationNKHHRIHTGEKPYWC
CCCCCCCCCCCCEEE		44.6728111955
455PhosphorylationHCGKTFCSKSNLSKH
CCCCEEECCCCCCCC		34.62-
467PhosphorylationSKHQRVHTGEGEAP-
CCCCCCCCCCCCCC-		33.7921815630
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZSC21_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZSC21_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZSC21_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZN446_HUMANZNF446physical
25416956
ZKSC7_HUMANZKSCAN7physical
25416956
ZN496_HUMANZNF496physical
25416956
TRI41_HUMANTRIM41physical
25416956
K1C40_HUMANKRT40physical
25416956
KR109_HUMANKRTAP10-9physical
25416956
KR108_HUMANKRTAP10-8physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZSC21_HUMAN

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Related Literatures of Post-Translational Modification

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