PCDG3_HUMAN - dbPTM
PCDG3_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PCDG3_HUMAN
UniProt AC Q9Y5H0
Protein Name Protocadherin gamma-A3
Gene Name PCDHGA3
Organism Homo sapiens (Human).
Sequence Length 932
Subcellular Localization Cell membrane
Single-pass type I membrane protein.
Protein Description Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain..
Protein Sequence MTNCLSFRNGRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQASGGGLASTPGSHFVGADGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKSEPLLITQDLLEMKGDSNLLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
72PhosphorylationRIVSRGRTQLFSLNP
EEEECCCEEEEEECC		32.2318077418
83PhosphorylationSLNPQSGSLVTAERI
EECCCCCCEEEEEEE		25.5518077418
135PhosphorylationDNAPNFPTEELEIKI
CCCCCCCHHHEEEEE		37.64-
156PhosphorylationGTRFPIKTAFDPDVG
CCCCCCCCCCCCCCC		33.0230206219
166PhosphorylationDPDVGINSLQNYKLS
CCCCCHHHHCCCCCC		29.4330206219
170PhosphorylationGINSLQNYKLSPNDY
CHHHHCCCCCCCCHH		10.5930206219
191PhosphorylationSVSEGAKYPELVLER
CCCCCCCCCHHHHHH		11.0420049867
215O-linked_GlycosylationHQLVLVASDGGDPVH
CEEEEEEECCCCCCC		29.3429351928
250PhosphorylationTQPEYRVSVWENVPV
CCCCEEEEEEECCCC		16.7128674151
259PhosphorylationWENVPVGTRLLTVNA
EECCCCCEEEEEEEC		20.5528674151
265N-linked_GlycosylationGTRLLTVNATDPDEG
CEEEEEEECCCCCCC		31.71UniProtKB CARBOHYD
302PhosphorylationNSVSGEVSILKSLDY
CCCCCCEEEHHCCCC		20.2224719451
306PhosphorylationGEVSILKSLDYEDAM
CCEEEHHCCCCCCCE		24.03-
309PhosphorylationSILKSLDYEDAMFYE
EEHHCCCCCCCEEEE		22.47-
315PhosphorylationDYEDAMFYEIKIEAQ
CCCCCEEEEEEEEEC		12.03-
419N-linked_GlycosylationREQISEYNISLRASD
HHHHHHCEEEEEECC		17.20UniProtKB CARBOHYD
545N-linked_GlycosylationGNPPLSSNVSLNLFV
CCCCCCCCEEEEEEE		24.83UniProtKB CARBOHYD
628PhosphorylationLHTGEVRTARALLDR
CCCCCHHHHHHHCCH		26.1820068231
685N-linked_GlycosylationLEPSAKPNDSDLTLY
CCCCCCCCCCCCHHH		61.79UniProtKB CARBOHYD
734O-linked_GlycosylationASGGGLASTPGSHFV
HCCCCCCCCCCCCCC		39.9329351928
735O-linked_GlycosylationSGGGLASTPGSHFVG
CCCCCCCCCCCCCCC		26.5129351928
753PhosphorylationVRAFLQTYSHEVSLT
HHHHHHHHCCEEEEC		8.6225884760
758PhosphorylationQTYSHEVSLTADSRK
HHHCCEEEECCCCCC		19.6124961811
775PhosphorylationLIFPQPNYADTLISQ
EECCCCCHHHCCCCH		16.7325884760
781PhosphorylationNYADTLISQESCEKS
CHHHCCCCHHHHCCC		30.8924961811
784PhosphorylationDTLISQESCEKSEPL
HCCCCHHHHCCCCCE		21.6824961811
819PhosphorylationPNTDWRFSQAQRPGT
CCCCCCCEECCCCCC		18.9425003641
879PhosphorylationTMGLSARYGPQFTLQ
CCCCCCCCCCCEEEE		32.6425884760
884PhosphorylationARYGPQFTLQHVPDY
CCCCCCEEEEECCCC		21.9124961811
891PhosphorylationTLQHVPDYRQNVYIP
EEEECCCCCCCEEEC		14.1824927040
896PhosphorylationPDYRQNVYIPGSNAT
CCCCCCEEECCCCCE		14.6725884760
900PhosphorylationQNVYIPGSNATLTNA
CCEEECCCCCEECCC		20.2424719451
903PhosphorylationYIPGSNATLTNAAGK
EECCCCCEECCCCCC		38.0627050516
910UbiquitinationTLTNAAGKRDGKAPA
EECCCCCCCCCCCCC		42.4632142685
914UbiquitinationAAGKRDGKAPAGGNG
CCCCCCCCCCCCCCC		56.3332142685
923UbiquitinationPAGGNGNKKKSGKKE
CCCCCCCCCCCCCCC		64.0832142685
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PCDG3_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PCDG3_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PCDG3_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PCDG3_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PCDG3_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory