CO1A1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CO1A1_HUMAN
• UniProt AC: P02452
• Protein Name: Collagen alpha-1(I) chain
• Gene Name: COL1A1
• Organism: Homo sapiens (Human).
• Sequence Length: 1464
• Subcellular Localization: Secreted, extracellular space, extracellular matrix .
• Protein Description: Type I collagen is a member of group I collagen (fibrillar forming collagen)..
• Protein Sequence: MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPTGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
103	O-linked_Glycosylation	PDGSESPTDQETTGV CCCCCCCCCCCCCCC	60.64	OGP
107	Phosphorylation	ESPTDQETTGVEGPK CCCCCCCCCCCCCCC	24.18	25332170
108	Phosphorylation	SPTDQETTGVEGPKG CCCCCCCCCCCCCCC	38.18	25332170
162	Pyrrolidone_carboxylic_acid	LGGNFAPQLSYGYDE CCCCCCCCCCCCCCC	39.34	-
162	Pyrrolidone_carboxylic_acid	LGGNFAPQLSYGYDE CCCCCCCCCCCCCCC	39.34	5529814
162	Pyrrolidone_carboxylic_acid	LGGNFAPQLSYGYDE CCCCCCCCCCCCCCC	39.34	5529814
170	Allysine	LSYGYDEKSTGGISV CCCCCCCCCCCCCCC	50.88	-
170	Deamination	LSYGYDEKSTGGISV CCCCCCCCCCCCCCC	50.88	5529814
171	Phosphorylation	SYGYDEKSTGGISVP CCCCCCCCCCCCCCC	30.18	20068231
172	O-linked_Glycosylation	YGYDEKSTGGISVPG CCCCCCCCCCCCCCC	50.96	OGP
172	Phosphorylation	YGYDEKSTGGISVPG CCCCCCCCCCCCCCC	50.96	20068231
176	Phosphorylation	EKSTGGISVPGPMGP CCCCCCCCCCCCCCC	26.07	26657352
184	Phosphorylation	VPGPMGPSGPRGLPG CCCCCCCCCCCCCCC	56.55	20068231
190	Hydroxylation	PSGPRGLPGPPGAPG CCCCCCCCCCCCCCC	56.95	-
193	Hydroxylation	PRGLPGPPGAPGPQG CCCCCCCCCCCCCCC	58.45	-
196	Hydroxylation	LPGPPGAPGPQGFQG CCCCCCCCCCCCCCC	61.99	-
205	Hydroxylation	PQGFQGPPGEPGEPG CCCCCCCCCCCCCCC	67.61	-
208	Hydroxylation	FQGPPGEPGEPGASG CCCCCCCCCCCCCCC	59.36	-
211	Hydroxylation	PPGEPGEPGASGPMG CCCCCCCCCCCCCCC	49.95	-
226	Hydroxylation	PRGPPGPPGKNGDDG CCCCCCCCCCCCCCC	72.76	-
241	Hydroxylation	EAGKPGRPGERGPPG CCCCCCCCCCCCCCC	55.71	-
247	Hydroxylation	RPGERGPPGPQGARG CCCCCCCCCCCCCCC	70.67	-
256	Hydroxylation	PQGARGLPGTAGLPG CCCCCCCCCCCCCCC	40.70	-
262	Hydroxylation	LPGTAGLPGMKGHRG CCCCCCCCCCCCCCC	39.66	-
265	Hydroxylation	TAGLPGMKGHRGFSG CCCCCCCCCCCCCCC	58.44	4319110
265	O-linked_Glycosylation	TAGLPGMKGHRGFSG CCCCCCCCCCCCCCC	58.44	4319110
271	Phosphorylation	MKGHRGFSGLDGAKG CCCCCCCCCCCCCCC	41.07	23911959
277	Acetylation	FSGLDGAKGDAGPAG CCCCCCCCCCCCCCC	63.95	30587783
289	Hydroxylation	PAGPKGEPGSPGENG CCCCCCCCCCCCCCC	58.17	-
291	Phosphorylation	GPKGEPGSPGENGAP CCCCCCCCCCCCCCC	40.21	21902226
292	Hydroxylation	PKGEPGSPGENGAPG CCCCCCCCCCCCCCC	61.09	-
298	Hydroxylation	SPGENGAPGQMGPRG CCCCCCCCCCCCCCC	34.64	-
307	Hydroxylation	QMGPRGLPGERGRPG CCCCCCCCCCCCCCC	45.48	-
313	Hydroxylation	LPGERGRPGAPGPAG CCCCCCCCCCCCCCC	46.23	-
334	Hydroxylation	ATGAAGPPGPTGPAG CCCCCCCCCCCCCCC	61.55	-
337	Phosphorylation	AAGPPGPTGPAGPPG CCCCCCCCCCCCCCC	62.81	28857561
343	Hydroxylation	PTGPAGPPGFPGAVG CCCCCCCCCCCCCCC	57.02	-
346	Hydroxylation	PAGPPGFPGAVGAKG CCCCCCCCCCCCCCC	35.43	-
363	Phosphorylation	GPQGPRGSEGPQGVR CCCCCCCCCCCCCCC	40.43	30087585
373	Hydroxylation	PQGVRGEPGPPGPAG CCCCCCCCCCCCCCC	64.51	-
376	Hydroxylation	VRGEPGPPGPAGAAG CCCCCCCCCCCCCCC	68.28	-
388	Hydroxylation	AAGPAGNPGADGQPG CCCCCCCCCCCCCCC	38.13	-
394	Hydroxylation	NPGADGQPGAKGANG CCCCCCCCCCCCCCC	50.68	-
403	Hydroxylation	AKGANGAPGIAGAPG CCCCCCCCCCCCCCC	35.80	-
409	Hydroxylation	APGIAGAPGFPGARG CCCCCCCCCCCCCCC	44.00	-
412	Hydroxylation	IAGAPGFPGARGPSG CCCCCCCCCCCCCCC	41.26	-
418	Phosphorylation	FPGARGPSGPQGPGG CCCCCCCCCCCCCCC	66.96	28857561
427	Hydroxylation	PQGPGGPPGPKGNSG CCCCCCCCCCCCCCC	75.01	-
430	Hydroxylation	PGGPPGPKGNSGEPG CCCCCCCCCCCCCCC	76.32	-
433	Phosphorylation	PPGPKGNSGEPGAPG CCCCCCCCCCCCCCC	53.88	30624053
436	Hydroxylation	PKGNSGEPGAPGSKG CCCCCCCCCCCCCCC	48.01	-
439	Hydroxylation	NSGEPGAPGSKGDTG CCCCCCCCCCCCCCC	54.21	-
441	Phosphorylation	GEPGAPGSKGDTGAK CCCCCCCCCCCCCCC	32.19	28857561
445	Phosphorylation	APGSKGDTGAKGEPG CCCCCCCCCCCCCCC	47.94	24719451
451	Hydroxylation	DTGAKGEPGPVGVQG CCCCCCCCCCCCCCC	62.14	-
460	Hydroxylation	PVGVQGPPGPAGEEG CCCCCCCCCCCCCCC	69.12	-
475	Hydroxylation	KRGARGEPGPTGLPG CCCCCCCCCCCCCCC	57.81	-
478	O-linked_Glycosylation	ARGEPGPTGLPGPPG CCCCCCCCCCCCCCC	58.21	55824433
481	Hydroxylation	EPGPTGLPGPPGERG CCCCCCCCCCCCCCC	55.37	-
490	Hydroxylation	PPGERGGPGSRGFPG CCCCCCCCCCCCCCC	40.17	-
496	Hydroxylation	GPGSRGFPGADGVAG CCCCCCCCCCCCCCC	39.63	-
505	Acetylation	ADGVAGPKGPAGERG CCCCCCCCCCCCCCC	76.30	19811517
505	Hydroxylation	ADGVAGPKGPAGERG CCCCCCCCCCCCCCC	76.30	-
513	Phosphorylation	GPAGERGSPGPAGPK CCCCCCCCCCCCCCC	32.67	25159151
514	Hydroxylation	PAGERGSPGPAGPKG CCCCCCCCCCCCCCC	56.46	-
520	Acetylation	SPGPAGPKGSPGEAG CCCCCCCCCCCCCCC	71.72	19811525
522	Phosphorylation	GPAGPKGSPGEAGRP CCCCCCCCCCCCCCC	35.54	25159151
523	Hydroxylation	PAGPKGSPGEAGRPG CCCCCCCCCCCCCCC	54.00	-
529	Hydroxylation	SPGEAGRPGEAGLPG CCCCCCCCCCCCCCC	44.02	-
535	Hydroxylation	RPGEAGLPGAKGLTG CCCCCCCCCCCCCCC	39.52	-
541	Phosphorylation	LPGAKGLTGSPGSPG CCCCCCCCCCCCCCC	44.26	30266825
543	Phosphorylation	GAKGLTGSPGSPGPD CCCCCCCCCCCCCCC	22.35	30266825
544	Hydroxylation	AKGLTGSPGSPGPDG CCCCCCCCCCCCCCC	48.93	-
546	Phosphorylation	GLTGSPGSPGPDGKT CCCCCCCCCCCCCCC	30.02	30266825
547	Hydroxylation	LTGSPGSPGPDGKTG CCCCCCCCCCCCCCC	65.34	-
556	Hydroxylation	PDGKTGPPGPAGQDG CCCCCCCCCCCCCCC	63.85	-
565	Hydroxylation	PAGQDGRPGPPGPPG CCCCCCCCCCCCCCC	66.23	-
571	Hydroxylation	RPGPPGPPGARGQAG CCCCCCCCCCCCCCC	55.80	-
583	Hydroxylation	QAGVMGFPGPKGAAG CCCCCCCCCCCCCCC	53.07	-
592	Hydroxylation	PKGAAGEPGKAGERG CCCCCCCCCCCCCCC	48.98	-
601	Hydroxylation	KAGERGVPGPPGAVG CCCCCCCCCCCCCCC	53.01	-
604	Hydroxylation	ERGVPGPPGAVGPAG CCCCCCCCCCCCCCC	49.65	-
622	Hydroxylation	EAGAQGPPGPAGPAG CCCCCCCCCCCCCCC	69.12	-
639	Phosphorylation	GEQGPAGSPGFQGLP CCCCCCCCCCCCCCC	24.77	21902226
640	Hydroxylation	EQGPAGSPGFQGLPG CCCCCCCCCCCCCCC	46.85	-
646	Hydroxylation	SPGFQGLPGPAGPPG CCCCCCCCCCCCCCC	54.25	-
652	Hydroxylation	LPGPAGPPGEAGKPG CCCCCCCCCCCCCCC	52.95	-
658	Hydroxylation	PPGEAGKPGEQGVPG CCCCCCCCCCCCCCC	51.11	-
664	Hydroxylation	KPGEQGVPGDLGAPG CCCCCCCCCCCCCCC	37.09	-
670	Hydroxylation	VPGDLGAPGPSGARG CCCCCCCCCCCCCCC	54.12	-
682	Hydroxylation	ARGERGFPGERGVQG CCCCCCCCCCCCCCC	46.70	-
691	Hydroxylation	ERGVQGPPGPAGPRG CCCCCCCCCCCCCCC	69.12	-
703	Hydroxylation	PRGANGAPGNDGAKG CCCCCCCCCCCCCCC	43.44	-
715	Hydroxylation	AKGDAGAPGAPGSQG CCCCCCCCCCCCCCC	38.26	-
718	Hydroxylation	DAGAPGAPGSQGAPG CCCCCCCCCCCCCCC	49.21	-
720	Phosphorylation	GAPGAPGSQGAPGLQ CCCCCCCCCCCCCCC	25.12	30242111
724	Hydroxylation	APGSQGAPGLQGMPG CCCCCCCCCCCCCCC	51.34	-
730	Hydroxylation	APGLQGMPGERGAAG CCCCCCCCCCCCCCC	48.60	-
739	Hydroxylation	ERGAAGLPGPKGDRG CCCCCCCCCCCCCCC	57.00	-
751	Hydroxylation	DRGDAGPKGADGSPG CCCCCCCCCCCCCCC	66.85	-
756	Phosphorylation	GPKGADGSPGKDGVR CCCCCCCCCCCCCCC	30.90	24114839
757	Hydroxylation	PKGADGSPGKDGVRG CCCCCCCCCCCCCCC	60.42	-
759	Acetylation	GADGSPGKDGVRGLT CCCCCCCCCCCCCCC	55.48	7668115
766	Phosphorylation	KDGVRGLTGPIGPPG CCCCCCCCCCCCCCC	43.68	20068231
772	Hydroxylation	LTGPIGPPGPAGAPG CCCCCCCCCCCCCCC	57.07	-
778	Hydroxylation	PPGPAGAPGDKGESG CCCCCCCCCCCCCCC	51.07	-
784	Phosphorylation	APGDKGESGPSGPAG CCCCCCCCCCCCCCC	65.75	30087585
787	Phosphorylation	DKGESGPSGPAGPTG CCCCCCCCCCCCCCC	62.02	30087585
799	Hydroxylation	PTGARGAPGDRGEPG CCCCCCCCCCCCCCC	48.30	-
805	Hydroxylation	APGDRGEPGPPGPAG CCCCCCCCCCCCCCC	64.51	-
808	Hydroxylation	DRGEPGPPGPAGFAG CCCCCCCCCCCCCCC	68.28	-
817	Hydroxylation	PAGFAGPPGADGQPG CCCCCCCCCCCCCCC	50.08	-
823	Hydroxylation	PPGADGQPGAKGEPG CCCCCCCCCCCCCCC	50.68	-
841	Hydroxylation	AKGDAGPPGPAGPAG CCCCCCCCCCCCCCC	61.56	-
850	Hydroxylation	PAGPAGPPGPIGNVG CCCCCCCCCCCCCCC	61.34	-
859	Hydroxylation	PIGNVGAPGAKGARG CCCCCCCCCCCCCCC	37.03	-
862	Hydroxylation	NVGAPGAKGARGSAG CCCCCCCCCCCCCCC	60.04	-
867	Phosphorylation	GAKGARGSAGPPGAT CCCCCCCCCCCCCCC	25.21	-
871	Hydroxylation	ARGSAGPPGATGFPG CCCCCCCCCCCCCCC	44.10	-
877	Hydroxylation	PPGATGFPGAAGRVG CCCCCCCCCCCCCCC	32.62	-
885	Hydroxylation	GAAGRVGPPGPSGNA CCCCCCCCCCCCCCC	28.02	-
886	Hydroxylation	AAGRVGPPGPSGNAG CCCCCCCCCCCCCCC	62.49	-
889	Phosphorylation	RVGPPGPSGNAGPPG CCCCCCCCCCCCCCC	51.06	-
895	Hydroxylation	PSGNAGPPGPPGPAG CCCCCCCCCCCCCCC	67.99	-
898	Hydroxylation	NAGPPGPPGPAGKEG CCCCCCCCCCCCCCC	68.28	-
919	Hydroxylation	ETGPAGRPGEVGPPG CCCCCCCCCCCCCCC	42.24	-
928	Hydroxylation	EVGPPGPPGPAGEKG CCCCCCCCCCCCCCC	68.28	-
936	Phosphorylation	GPAGEKGSPGADGPA CCCCCCCCCCCCCCC	31.09	28857561
937	Hydroxylation	PAGEKGSPGADGPAG CCCCCCCCCCCCCCC	51.14	-
946	Hydroxylation	ADGPAGAPGTPGPQG CCCCCCCCCCCCCCC	46.39	-
948	O-linked_Glycosylation	GPAGAPGTPGPQGIA CCCCCCCCCCCCCCC	24.82	OGP
948	Phosphorylation	GPAGAPGTPGPQGIA CCCCCCCCCCCCCCC	24.82	28857561
964	Hydroxylation	QRGVVGLPGQRGERG CCCCCCCCCCCCCCC	30.83	-
973	Hydroxylation	QRGERGFPGLPGPSG CCCCCCCCCCCCCCC	46.35	-
976	Hydroxylation	ERGFPGLPGPSGEPG CCCCCCCCCCCCCCC	59.57	-
979	Phosphorylation	FPGLPGPSGEPGKQG CCCCCCCCCCCCCCC	62.80	22210691
982	Hydroxylation	LPGPSGEPGKQGPSG CCCCCCCCCCCCCCC	59.82	-
988	Phosphorylation	EPGKQGPSGASGERG CCCCCCCCCCCCCCC	54.54	30087585
991	Phosphorylation	KQGPSGASGERGPPG CCCCCCCCCCCCCCC	44.72	30087585
997	Hydroxylation	ASGERGPPGPMGPPG CCCCCCCCCCCCCCC	63.44	-
1000	Sulfoxidation	ERGPPGPMGPPGLAG CCCCCCCCCCCCCCC	18.24	30846556
1003	Hydroxylation	PPGPMGPPGLAGPPG CCCCCCCCCCCCCCC	44.71	-
1004	Ubiquitination	PGPMGPPGLAGPPGE CCCCCCCCCCCCCCC	31.15	21963094
1009	Hydroxylation	PPGLAGPPGESGREG CCCCCCCCCCCCCCC	59.26	-
1018	Hydroxylation	ESGREGAPGAEGSPG CCCCCCCCCCCCCCC	54.08	-
1023	Phosphorylation	GAPGAEGSPGRDGSP CCCCCCCCCCCCCCC	18.71	21815630
1024	Hydroxylation	APGAEGSPGRDGSPG CCCCCCCCCCCCCCC	53.33	-
1029	Phosphorylation	GSPGRDGSPGAKGDR CCCCCCCCCCCCCCC	25.17	25159151
1033	Hydroxylation	RDGSPGAKGDRGETG CCCCCCCCCCCCCCC	68.23	-
1039	Phosphorylation	AKGDRGETGPAGPPG CCCCCCCCCCCCCCC	51.82	23532336
1045	Hydroxylation	ETGPAGPPGAPGAPG CCCCCCCCCCCCCCC	51.14	-
1048	Hydroxylation	PAGPPGAPGAPGAPG CCCCCCCCCCCCCCC	45.45	-
1051	Hydroxylation	PPGAPGAPGAPGPVG CCCCCCCCCCCCCCC	45.45	-
1096	Hydroxylation	PQGPRGDKGETGEQG CCCCCCCCCCCCCCC	62.56	-
1108	Hydroxylation	EQGDRGIKGHRGFSG CCCCCCCCCCCCCCC	52.03	-
1108	O-linked_Glycosylation	EQGDRGIKGHRGFSG CCCCCCCCCCCCCCC	52.03	-
1114	Phosphorylation	IKGHRGFSGLQGPPG CCCCCCCCCCCCCCC	41.22	27251275
1120	Hydroxylation	FSGLQGPPGPPGSPG CCCCCCCCCCCCCCC	74.81	-
1123	Hydroxylation	LQGPPGPPGSPGEQG CCCCCCCCCCCCCCC	62.91	-
1125	Phosphorylation	GPPGPPGSPGEQGPS CCCCCCCCCCCCCCC	35.19	26657352
1126	Hydroxylation	PPGPPGSPGEQGPSG CCCCCCCCCCCCCCC	57.14	-
1132	Phosphorylation	SPGEQGPSGASGPAG CCCCCCCCCCCCCCC	54.54	27251275
1135	Phosphorylation	EQGPSGASGPAGPRG CCCCCCCCCCCCCCC	49.16	27251275
1144	Hydroxylation	PAGPRGPPGSAGAPG CCCCCCCCCCCCCCC	52.79	-
1159	Hydroxylation	KDGLNGLPGPIGPPG CCCCCCCCCCCCCCC	48.16	-
1164	Hydroxylation	GLPGPIGPPGPRGRT CCCCCCCCCCCCCCC	31.24	-
1165	Hydroxylation	LPGPIGPPGPRGRTG CCCCCCCCCCCCCCC	61.27	-
1171	Phosphorylation	PPGPRGRTGDAGPVG CCCCCCCCCCCCCCC	42.09	22210691
1179	Hydroxylation	GDAGPVGPPGPPGPP CCCCCCCCCCCCCCC	30.79	-
1180	Hydroxylation	DAGPVGPPGPPGPPG CCCCCCCCCCCCCCC	63.09	-
1182	Hydroxylation	GPVGPPGPPGPPGPP CCCCCCCCCCCCCCC	36.13	-
1183	Hydroxylation	PVGPPGPPGPPGPPG CCCCCCCCCCCCCCC	74.06	-
1185	Hydroxylation	GPPGPPGPPGPPGPP CCCCCCCCCCCCCCC	36.13	-
1186	Hydroxylation	PPGPPGPPGPPGPPS CCCCCCCCCCCCCCC	74.06	-
1189	Hydroxylation	PPGPPGPPGPPSAGF CCCCCCCCCCCCCCC	74.06	-
1192	Hydroxylation	PPGPPGPPSAGFDFS CCCCCCCCCCCCCCC	42.60	-
1193	Phosphorylation	PGPPGPPSAGFDFSF CCCCCCCCCCCCCCC	44.12	22210691
1199	Phosphorylation	PSAGFDFSFLPQPPQ CCCCCCCCCCCCCCC	27.93	22210691
1208	Allysine	LPQPPQEKAHDGGRY CCCCCCCCCCCCCCE	45.86	-
1208	Deamination	LPQPPQEKAHDGGRY CCCCCCCCCCCCCCE	45.86	-
1220	Ubiquitination	GRYYRADDANVVRDR CCEEECCCCCCCCCC	38.77	21963094
1234	O-linked_Glycosylation	RDLEVDTTLKSLSQQ CCCHHHHHHHHHHHH	27.94	55824577
1236	Ubiquitination	LEVDTTLKSLSQQIE CHHHHHHHHHHHHHH	47.46	29967540
1237	Phosphorylation	EVDTTLKSLSQQIEN HHHHHHHHHHHHHHH	36.04	29632367
1239	Phosphorylation	DTTLKSLSQQIENIR HHHHHHHHHHHHHCC	27.42	29632367
1244	Ubiquitination	SLSQQIENIRSPEGS HHHHHHHHCCCCCCC	36.28	21963094
1247	Phosphorylation	QQIENIRSPEGSRKN HHHHHCCCCCCCCCC	24.41	25159151
1270	Ubiquitination	KMCHSDWKSGEYWID HCCCCCCCCCCEEEC	54.28	29967540
1271	Phosphorylation	MCHSDWKSGEYWIDP CCCCCCCCCCEEECC	32.38	29759185
1274	Phosphorylation	SDWKSGEYWIDPNQG CCCCCCCEEECCCCC	15.93	29759185
1295	Phosphorylation	KVFCNMETGETCVYP EEEECCCCCCCEECC	29.55	26552605
1298	Phosphorylation	CNMETGETCVYPTQP ECCCCCCCEECCCCC	14.49	26552605
1301	Phosphorylation	ETGETCVYPTQPSVA CCCCCEECCCCCCHH	11.60	26552605
1303	Phosphorylation	GETCVYPTQPSVAQK CCCEECCCCCCHHHC	35.11	26552605
1306	Phosphorylation	CVYPTQPSVAQKNWY EECCCCCCHHHCCCE	21.92	26552605
1310	Ubiquitination	TQPSVAQKNWYISKN CCCCHHHCCCEECCC	39.45	21963094
1316	Ubiquitination	QKNWYISKNPKDKRH HCCCEECCCCCCCCE	68.65	29967540
1359	Phosphorylation	LTFLRLMSTEASQNI HHHHHHHCCCHHHCE	27.90	28555341
1360	Phosphorylation	TFLRLMSTEASQNIT HHHHHHCCCHHHCEE	22.93	27251275
1365	N-linked_Glycosylation	MSTEASQNITYHCKN HCCCHHHCEEEEECC	26.52	UniProtKB CARBOHYD
1385	Ubiquitination	DQQTGNLKKALLLQG CCCCCCHHHHHHHCC	39.75	29967540
1393	Phosphorylation	KALLLQGSNEIEIRA HHHHHCCCCEEEEEE	20.52	27251275
1430	Ubiquitination	GKTVIEYKTTKTSRL CCEEEEEECCCCCCC	36.61	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CO1A1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CO1A1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CO1A1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IBP3_HUMAN	IGFBP3	physical	12735930
ITA2_HUMAN	ITGA2	physical	2156854
ITB1_HUMAN	ITGB1	physical	2156854
NID1_HUMAN	NID1	physical	9733643
NID1_MOUSE	Nid1	physical	9733643
NID2_HUMAN	NID2	physical	9733643
SPRC_HUMAN	SPARC	physical	2745554
MMP2_HUMAN	MMP2	physical	11368514
RINI_HUMAN	RNH1	physical	22939629
CO1A1_HUMAN	COL1A1	physical	18375391
CO1A2_HUMAN	COL1A2	physical	18375391
PDGFA_HUMAN	PDGFA	physical	8900172
PDGFB_HUMAN	PDGFB	physical	8900172

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 114000: Caffey disease (CAFFD)
• 130000: Ehlers-Danlos syndrome, classic type (EDS)
• 130060: Ehlers-Danlos syndrome 7A (EDS7A)
• 166200: Osteogenesis imperfecta 1 (OI1)
• 166210: Osteogenesis imperfecta 2 (OI2)
• 259420: Osteogenesis imperfecta 3 (OI3)
• 166220: Osteogenesis imperfecta 4 (OI4)
• 166710: Osteoporosis (OSTEOP)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.