dbPTM

SYTC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SYTC_HUMAN
UniProt AC	P26639
Protein Name	Threonine--tRNA ligase, cytoplasmic
Gene Name	TARS
Organism	Homo sapiens (Human).
Sequence Length	723
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MFEEKASSPSGKMGGEEKPIGAGEEKQKEGGKKKNKEGSGDGGRAELNPWPEYIYTRLEMYNILKAEHDSILAEKAEKDSKPIKVTLPDGKQVDAESWKTTPYQIACGISQGLADNTVIAKVNNVVWDLDRPLEEDCTLELLKFEDEEAQAVYWHSSAHIMGEAMERVYGGCLCYGPPIENGFYYDMYLEEGGVSSNDFSSLEALCKKIIKEKQAFERLEVKKETLLAMFKYNKFKCRILNEKVNTPTTTVYRCGPLIDLCRGPHVRHTGKIKALKIHKNSSTYWEGKADMETLQRIYGISFPDPKMLKEWEKFQEEAKNRDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Ubiquitination	---MFEEKASSPSGK ---CCCCCCCCCCCC	46.50	-
7	Phosphorylation	-MFEEKASSPSGKMG -CCCCCCCCCCCCCC	54.58	26074081
8	Phosphorylation	MFEEKASSPSGKMGG CCCCCCCCCCCCCCC	28.13	28176443
10	Phosphorylation	EEKASSPSGKMGGEE CCCCCCCCCCCCCCC	53.66	28176443
12	Acetylation	KASSPSGKMGGEEKP CCCCCCCCCCCCCCC	38.41	25953088
12	Ubiquitination	KASSPSGKMGGEEKP CCCCCCCCCCCCCCC	38.41	27667366
13	Sulfoxidation	ASSPSGKMGGEEKPI CCCCCCCCCCCCCCC	10.73	30846556
18	Sumoylation	GKMGGEEKPIGAGEE CCCCCCCCCCCCCHH	37.32	-
18	Acetylation	GKMGGEEKPIGAGEE CCCCCCCCCCCCCHH	37.32	23749302
18	Sumoylation	GKMGGEEKPIGAGEE CCCCCCCCCCCCCHH	37.32	-
18	Ubiquitination	GKMGGEEKPIGAGEE CCCCCCCCCCCCCHH	37.32	-
26	Ubiquitination	PIGAGEEKQKEGGKK CCCCCHHHHHCCCCC	63.47	27667366
39	Phosphorylation	KKKNKEGSGDGGRAE CCCCCCCCCCCCCCC	34.50	25159151
39 (in isoform 2)	Phosphorylation	-	34.50	27251275
53	Phosphorylation	ELNPWPEYIYTRLEM CCCCCCHHHHHHHHH	8.64	28796482
55	Phosphorylation	NPWPEYIYTRLEMYN CCCCHHHHHHHHHHH	5.72	28796482
55 (in isoform 2)	Phosphorylation	-	5.72	27642862
56	Phosphorylation	PWPEYIYTRLEMYNI CCCHHHHHHHHHHHH	21.15	28796482
60	Sulfoxidation	YIYTRLEMYNILKAE HHHHHHHHHHHHHHH	3.53	30846556
61 (in isoform 2)	Phosphorylation	-	6.95	27642862
65	Acetylation	LEMYNILKAEHDSIL HHHHHHHHHHHHHHH	48.18	26051181
65	Ubiquitination	LEMYNILKAEHDSIL HHHHHHHHHHHHHHH	48.18	21906983
70	Phosphorylation	ILKAEHDSILAEKAE HHHHHHHHHHHHHHH	22.78	25159151
75	Acetylation	HDSILAEKAEKDSKP HHHHHHHHHHCCCCC	57.13	26051181
75	Ubiquitination	HDSILAEKAEKDSKP HHHHHHHHHHCCCCC	57.13	21906983
78	Ubiquitination	ILAEKAEKDSKPIKV HHHHHHHCCCCCEEE	72.64	22817900
80	Phosphorylation	AEKAEKDSKPIKVTL HHHHHCCCCCEEEEC	51.94	20068231
81	Ubiquitination	EKAEKDSKPIKVTLP HHHHCCCCCEEEECC	61.98	23503661
84	Ubiquitination	EKDSKPIKVTLPDGK HCCCCCEEEECCCCC	37.38	29967540
86	Phosphorylation	DSKPIKVTLPDGKQV CCCCEEEECCCCCEE	27.80	20068231
91	Acetylation	KVTLPDGKQVDAESW EEECCCCCEECHHHH	55.30	26051181
91	Ubiquitination	KVTLPDGKQVDAESW EEECCCCCEECHHHH	55.30	21906983
99	Ubiquitination	QVDAESWKTTPYQIA EECHHHHCCCCHHHH	52.37	29967540
101	Phosphorylation	DAESWKTTPYQIACG CHHHHCCCCHHHHHC	19.10	24719451
103	Phosphorylation	ESWKTTPYQIACGIS HHHCCCCHHHHHCCC	15.51	20090780
107	S-nitrosocysteine	TTPYQIACGISQGLA CCCHHHHHCCCCCCC	5.48	-
107	Glutathionylation	TTPYQIACGISQGLA CCCHHHHHCCCCCCC	5.48	22555962
107	S-nitrosylation	TTPYQIACGISQGLA CCCHHHHHCCCCCCC	5.48	19483679
107	S-palmitoylation	TTPYQIACGISQGLA CCCHHHHHCCCCCCC	5.48	29575903
110	Phosphorylation	YQIACGISQGLADNT HHHHHCCCCCCCCCC	11.95	21712546
121	Ubiquitination	ADNTVIAKVNNVVWD CCCCEEEEECCEEEC	34.08	29967540
137	S-palmitoylation	DRPLEEDCTLELLKF CCCCCCCCEEEEEEC	5.45	29575903
188	Phosphorylation	NGFYYDMYLEEGGVS CCEEEEEEEECCCCC	14.20	25332170
200	Phosphorylation	GVSSNDFSSLEALCK CCCCCCCHHHHHHHH	36.56	-
201	Phosphorylation	VSSNDFSSLEALCKK CCCCCCHHHHHHHHH	30.17	-
211	Ubiquitination	ALCKKIIKEKQAFER HHHHHHHHHHHHHHH	63.43	-
213	Acetylation	CKKIIKEKQAFERLE HHHHHHHHHHHHHHH	41.76	25953088
213	Malonylation	CKKIIKEKQAFERLE HHHHHHHHHHHHHHH	41.76	26320211
213	Ubiquitination	CKKIIKEKQAFERLE HHHHHHHHHHHHHHH	41.76	29967540
222	Ubiquitination	AFERLEVKKETLLAM HHHHHHCCHHHHHHH	35.20	17203973
223	Ubiquitination	FERLEVKKETLLAMF HHHHHCCHHHHHHHH	62.19	29967540
225	Phosphorylation	RLEVKKETLLAMFKY HHHCCHHHHHHHHHC	35.63	20068231
231	Acetylation	ETLLAMFKYNKFKCR HHHHHHHHCCCCEEE	34.52	26051181
231	Ubiquitination	ETLLAMFKYNKFKCR HHHHHHHHCCCCEEE	34.52	23000965
234	Ubiquitination	LAMFKYNKFKCRILN HHHHHCCCCEEEECC	43.01	23000965
236	Ubiquitination	MFKYNKFKCRILNEK HHHCCCCEEEECCCC	24.98	23000965
243	Acetylation	KCRILNEKVNTPTTT EEEECCCCCCCCCCE	39.45	19608861
243	Ubiquitination	KCRILNEKVNTPTTT EEEECCCCCCCCCCE	39.45	23000965
246	Phosphorylation	ILNEKVNTPTTTVYR ECCCCCCCCCCEEEE	25.62	21815630
246	Ubiquitination	ILNEKVNTPTTTVYR ECCCCCCCCCCEEEE	25.62	29967540
248	Phosphorylation	NEKVNTPTTTVYRCG CCCCCCCCCEEEECC	32.81	23186163
252	Nitration	NTPTTTVYRCGPLID CCCCCEEEECCCHHH	9.70	-
252	Phosphorylation	NTPTTTVYRCGPLID CCCCCEEEECCCHHH	9.70	28985074
255	Ubiquitination	TTTVYRCGPLIDLCR CCEEEECCCHHHHCC	15.85	17203973
256	Ubiquitination	TTVYRCGPLIDLCRG CEEEECCCHHHHCCC	29.75	29967540
262	Methylation	GPLIDLCRGPHVRHT CCHHHHCCCCCCCCC	69.81	115918221
264	Ubiquitination	LIDLCRGPHVRHTGK HHHHCCCCCCCCCCE	11.93	23000965
267	Ubiquitination	LCRGPHVRHTGKIKA HCCCCCCCCCCEEEE	20.72	23000965
269	Ubiquitination	RGPHVRHTGKIKALK CCCCCCCCCEEEEEE	29.61	23000965
276	Ubiquitination	TGKIKALKIHKNSST CCEEEEEEEECCCCC	47.85	21890473
276	Acetylation	TGKIKALKIHKNSST CCEEEEEEEECCCCC	47.85	19608861
276	Ubiquitination	TGKIKALKIHKNSST CCEEEEEEEECCCCC	47.85	23000965
279	Acetylation	IKALKIHKNSSTYWE EEEEEEECCCCCCCC	63.10	26051181
279	Ubiquitination	IKALKIHKNSSTYWE EEEEEEECCCCCCCC	63.10	21906983
281	Phosphorylation	ALKIHKNSSTYWEGK EEEEECCCCCCCCCC	28.94	20873877
282	Phosphorylation	LKIHKNSSTYWEGKA EEEECCCCCCCCCCC	34.60	28348404
283	Phosphorylation	KIHKNSSTYWEGKAD EEECCCCCCCCCCCC	32.26	22210691
284	Phosphorylation	IHKNSSTYWEGKADM EECCCCCCCCCCCCH	11.92	-
288	Acetylation	SSTYWEGKADMETLQ CCCCCCCCCCHHHHH	29.69	26051181
288	Ubiquitination	SSTYWEGKADMETLQ CCCCCCCCCCHHHHH	29.69	21906983
291	Sulfoxidation	YWEGKADMETLQRIY CCCCCCCHHHHHHHH	5.18	30846556
293	Phosphorylation	EGKADMETLQRIYGI CCCCCHHHHHHHHCC	22.89	23312004
298	Nitration	METLQRIYGISFPDP HHHHHHHHCCCCCCH	15.59	-
298	Phosphorylation	METLQRIYGISFPDP HHHHHHHHCCCCCCH	15.59	25159151
301	Phosphorylation	LQRIYGISFPDPKML HHHHHCCCCCCHHHH	26.77	28152594
306	Acetylation	GISFPDPKMLKEWEK CCCCCCHHHHHHHHH	65.33	19608861
306	Ubiquitination	GISFPDPKMLKEWEK CCCCCCHHHHHHHHH	65.33	21906983
309	Acetylation	FPDPKMLKEWEKFQE CCCHHHHHHHHHHHH	58.23	27452117
309	Malonylation	FPDPKMLKEWEKFQE CCCHHHHHHHHHHHH	58.23	26320211
309	Ubiquitination	FPDPKMLKEWEKFQE CCCHHHHHHHHHHHH	58.23	27667366
312	Ubiquitination	PKMLKEWEKFQEEAK HHHHHHHHHHHHHHH	45.12	27667366
313	Acetylation	KMLKEWEKFQEEAKN HHHHHHHHHHHHHHC	54.11	23954790
313	Ubiquitination	KMLKEWEKFQEEAKN HHHHHHHHHHHHHHC	54.11	22817900
314 (in isoform 2)	Phosphorylation	-	8.18	27251275
319	Ubiquitination	EKFQEEAKNRDHRKI HHHHHHHHCCCHHHH	56.65	27667366
321	Ubiquitination	FQEEAKNRDHRKIGR HHHHHHCCCHHHHCC	40.17	21963094
331 (in isoform 2)	Phosphorylation	-	50.13	27251275
333	Phosphorylation	IGRDQELYFFHELSP HCCCCEEEEEEECCC	11.93	-
339	Ubiquitination	LYFFHELSPGSCFFL EEEEEECCCCCEEEE	24.99	21890473
339	Acetylation	LYFFHELSPGSCFFL EEEEEECCCCCEEEE	24.99	19608861
339	Phosphorylation	LYFFHELSPGSCFFL EEEEEECCCCCEEEE	24.99	25159151
339	Ubiquitination	LYFFHELSPGSCFFL EEEEEECCCCCEEEE	24.99	21890473
342	Ubiquitination	FHELSPGSCFFLPKG EEECCCCCEEEECCC	15.90	32015554
346	Ubiquitination	SPGSCFFLPKGAYIY CCCCEEEECCCHHHH	1.83	21890473
346	Ubiquitination	SPGSCFFLPKGAYIY CCCCEEEECCCHHHH	1.83	21890473
352	Ubiquitination	FLPKGAYIYNALIEF EECCCHHHHHHHHHH	1.80	27667366
353	Phosphorylation	LPKGAYIYNALIEFI ECCCHHHHHHHHHHH	5.02	18083107
367	Methylation	IRSEYRKRGFQEVVT HHHHHHHCCCEECCC	42.00	115918225
374	Phosphorylation	RGFQEVVTPNIFNSR CCCEECCCCCCCCCC	18.78	27050516
380	Phosphorylation	VTPNIFNSRLWMTSG CCCCCCCCCEEEECC	20.29	21712546
409	Ubiquitination	EKELFALKPMNCPGH EHHHHCCCCCCCCCC	38.50	-
433	Methylation	SWRELPLRLADFGVL CHHHCCCHHHHHCEE	26.37	115918229
446	Phosphorylation	VLHRNELSGALTGLT EEEHHHHHHHHHHHH	18.81	27050516
450	Phosphorylation	NELSGALTGLTRVRR HHHHHHHHHHHHHEE	29.61	23186163
453	Phosphorylation	SGALTGLTRVRRFQQ HHHHHHHHHHEEHHH	28.59	23917254
469	Sulfoxidation	DAHIFCAMEQIEDEI CCEEEEEHHHHHHHH	4.02	30846556
483 (in isoform 2)	Phosphorylation	-	4.47	27251275
493	Phosphorylation	VYSVFGFSFKLNLST HHHHHCEEEEEECCC	23.11	24719451
499	Phosphorylation	FSFKLNLSTRPEKFL EEEEEECCCCCHHHH	22.69	20068231
500	Phosphorylation	SFKLNLSTRPEKFLG EEEEECCCCCHHHHC	54.10	20068231
504	Acetylation	NLSTRPEKFLGDIEV ECCCCCHHHHCCHHH	48.88	26051181
504	Ubiquitination	NLSTRPEKFLGDIEV ECCCCCHHHHCCHHH	48.88	23000965
517	Ubiquitination	EVWDQAEKQLENSLN HHHHHHHHHHHHHHH	64.30	32015554
529	Acetylation	SLNEFGEKWELNSGD HHHHHHHCEEECCCC	46.47	23236377
529	Ubiquitination	SLNEFGEKWELNSGD HHHHHHHCEEECCCC	46.47	21906983
534	Phosphorylation	GEKWELNSGDGAFYG HHCEEECCCCCCCCC	51.38	28152594
537	Ubiquitination	WELNSGDGAFYGPKI EEECCCCCCCCCCEE	22.55	21890473
537	Ubiquitination	WELNSGDGAFYGPKI EEECCCCCCCCCCEE	22.55	23000965
540	Phosphorylation	NSGDGAFYGPKIDIQ CCCCCCCCCCEEEEE	31.80	28152594
543	Ubiquitination	DGAFYGPKIDIQIKD CCCCCCCEEEEEEEC	48.96	23000965
549	Acetylation	PKIDIQIKDAIGRYH CEEEEEEECCCCCEE	25.40	25953088
549	Ubiquitination	PKIDIQIKDAIGRYH CEEEEEEECCCCCEE	25.40	23000965
550	Ubiquitination	KIDIQIKDAIGRYHQ EEEEEEECCCCCEEE	45.08	32015554
562	Ubiquitination	YHQCATIQLDFQLPI EEEEEEEEEEEECEE	30.53	21963094
574	Phosphorylation	LPIRFNLTYVSHDGD CEEEEEEEEEECCCC	24.00	28152594
575	Phosphorylation	PIRFNLTYVSHDGDD EEEEEEEEEECCCCC	11.79	28152594
576	Ubiquitination	IRFNLTYVSHDGDDK EEEEEEEEECCCCCC	3.27	23000965
577	Phosphorylation	RFNLTYVSHDGDDKK EEEEEEEECCCCCCC	12.87	28152594
582	Ubiquitination	YVSHDGDDKKRPVIV EEECCCCCCCCCEEE	65.00	21890473
582	Ubiquitination	YVSHDGDDKKRPVIV EEECCCCCCCCCEEE	65.00	23000965
583	Ubiquitination	VSHDGDDKKRPVIVH EECCCCCCCCCEEEH	56.26	22817900
584	Acetylation	SHDGDDKKRPVIVHR ECCCCCCCCCEEEHH	69.77	19811577
584	Ubiquitination	SHDGDDKKRPVIVHR ECCCCCCCCCEEEHH	69.77	21963094
611	Ubiquitination	LTENYGGKWPFWLSP HHCCCCCCCCCEECC	47.53	21963094
616	Ubiquitination	GGKWPFWLSPRQVMV CCCCCCEECCCEEEE	5.30	22817900
617	Ubiquitination	GKWPFWLSPRQVMVV CCCCCEECCCEEEEE	14.50	21963094
622	Sulfoxidation	WLSPRQVMVVPVGPT EECCCEEEEEECCCC	1.58	30846556
636	Acetylation	TCDEYAQKVRQQFHD CHHHHHHHHHHHHHC	31.08	25953088
636	Ubiquitination	TCDEYAQKVRQQFHD CHHHHHHHHHHHHHC	31.08	23000965
644	Ubiquitination	VRQQFHDAKFMADID HHHHHHCCCCCCCCC	9.83	21963094
645	Ubiquitination	RQQFHDAKFMADIDL HHHHHCCCCCCCCCC	41.55	21963094
647	Sulfoxidation	QFHDAKFMADIDLDP HHHCCCCCCCCCCCC	3.01	21406390
656	Glutathionylation	DIDLDPGCTLNKKIR CCCCCCCCCCCHHHH	4.81	22555962
657	Phosphorylation	IDLDPGCTLNKKIRN CCCCCCCCCCHHHHH	39.00	30576142
660	Acetylation	DPGCTLNKKIRNAQL CCCCCCCHHHHHHHH	53.33	23954790
660	Malonylation	DPGCTLNKKIRNAQL CCCCCCCHHHHHHHH	53.33	26320211
660	Ubiquitination	DPGCTLNKKIRNAQL CCCCCCCHHHHHHHH	53.33	21963094
661	Ubiquitination	PGCTLNKKIRNAQLA CCCCCCHHHHHHHHH	45.91	22817900
669	Ubiquitination	IRNAQLAQYNFILVV HHHHHHHEEEEEEEE	42.15	23000965
678	Ubiquitination	NFILVVGEKEKISGT EEEEEECCCEEEEEE	46.57	21963094
681	Ubiquitination	LVVGEKEKISGTVNI EEECCCEEEEEEEEE	53.92	29967540
685	Phosphorylation	EKEKISGTVNIRTRD CCEEEEEEEEEECCC	12.00	25599653
693	Ubiquitination	VNIRTRDNKVHGERT EEEECCCCCCCCCCC	44.98	21963094
694	Ubiquitination	NIRTRDNKVHGERTI EEECCCCCCCCCCCH	39.64	22817900
700	Phosphorylation	NKVHGERTISETIER CCCCCCCCHHHHHHH	25.26	30108239
702	Phosphorylation	VHGERTISETIERLQ CCCCCCHHHHHHHHH	28.24	21815630
704	Phosphorylation	GERTISETIERLQQL CCCCHHHHHHHHHHH	22.73	30108239
712	Sumoylation	IERLQQLKEFRSKQA HHHHHHHHHHHHHHH	50.93	-
712	Acetylation	IERLQQLKEFRSKQA HHHHHHHHHHHHHHH	50.93	25953088
712	Sumoylation	IERLQQLKEFRSKQA HHHHHHHHHHHHHHH	50.93	-
712	Ubiquitination	IERLQQLKEFRSKQA HHHHHHHHHHHHHHH	50.93	23000965
714	Ubiquitination	RLQQLKEFRSKQAEE HHHHHHHHHHHHHHH	11.61	29967540
716	Phosphorylation	QQLKEFRSKQAEEEF HHHHHHHHHHHHHHC	34.15	23911959
717	Ubiquitination	QLKEFRSKQAEEEF- HHHHHHHHHHHHHC-	49.63	23000965
727	Ubiquitination	EEEF----------- HHHC-----------		29967540
735 (in isoform 2)	Phosphorylation	-		27251275
745	Ubiquitination	----------------------------- -----------------------------		23000965
750	Ubiquitination	---------------------------------- ----------------------------------		23000965

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SYTC_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SYTC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SYTC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCPE_HUMAN	CCT5	physical	22939629
ACPH_HUMAN	APEH	physical	22863883
COR1B_HUMAN	CORO1B	physical	22863883
NIBL1_HUMAN	FAM129B	physical	22863883
NUDC_HUMAN	NUDC	physical	22863883
PAPOA_HUMAN	PAPOLA	physical	22863883
PUF60_HUMAN	PUF60	physical	22863883
SET_HUMAN	SET	physical	22863883
ZYX_HUMAN	ZYX	physical	22863883
CG025_HUMAN	C7orf25	physical	25416956
SYTC2_HUMAN	TARSL2	physical	25416956
AASD1_HUMAN	AARSD1	physical	26344197
AHNK_HUMAN	AHNAK	physical	26344197
CHK1_HUMAN	CHEK1	physical	26344197
E2AK4_HUMAN	EIF2AK4	physical	26344197
SYFA_HUMAN	FARSA	physical	26344197
SYFB_HUMAN	FARSB	physical	26344197
GARS_HUMAN	GARS	physical	26344197
GFPT1_HUMAN	GFPT1	physical	26344197
HNRPD_HUMAN	HNRNPD	physical	26344197
NAA50_HUMAN	NAA50	physical	26344197
NH2L1_HUMAN	NHP2L1	physical	26344197
SYSC_HUMAN	SARS	physical	26344197
SYSM_HUMAN	SARS2	physical	26344197
SFPQ_HUMAN	SFPQ	physical	26344197
TARB1_HUMAN	TARBP1	physical	26344197
UBCP1_HUMAN	UBLCP1	physical	26344197

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
DB00156	L-Threonine

Regulatory Network of SYTC_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-243, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Global survey of phosphotyrosine signaling identifies oncogenickinases in lung cancer."; Rikova K., Guo A., Zeng Q., Possemato A., Yu J., Haack H., Nardone J.,Lee K., Reeves C., Li Y., Hu Y., Tan Z., Stokes M., Sullivan L.,Mitchell J., Wetzel R., Macneill J., Ren J.M., Yuan J.,Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D., Zhou X.,Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.; Cell 131:1190-1203(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-298, AND MASSSPECTROMETRY.	18083107 [Abstract]
Ubiquitylation
Reference	PubMed
"The proteomic reactor facilitates the analysis of affinity-purifiedproteins by mass spectrometry: application for identifyingubiquitinated proteins in human cells."; Vasilescu J., Zweitzig D.R., Denis N.J., Smith J.C., Ethier M.,Haines D.S., Figeys D.; J. Proteome Res. 6:298-305(2007). Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-222, AND MASSSPECTROMETRY.	17203973 [Abstract]