CG025_HUMAN - dbPTM
CG025_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CG025_HUMAN
UniProt AC Q9BPX7
Protein Name UPF0415 protein C7orf25
Gene Name C7orf25
Organism Homo sapiens (Human).
Sequence Length 421
Subcellular Localization
Protein Description
Protein Sequence MSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNALLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERATVLIKRINVVPDQPSERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDYTTDSEH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
15UbiquitinationCERIAIAKELIKRAE
HHHHHHHHHHHHHHH		47.1129967540
23PhosphorylationELIKRAESLSRSRKG
HHHHHHHHHHHHHCC		30.5728102081
25PhosphorylationIKRAESLSRSRKGGI
HHHHHHHHHHHCCCC		37.1728102081
37UbiquitinationGGIEGGAKLCSKLKA
CCCCHHHHHHHHHHH		53.9929967540
51UbiquitinationAELKFLQKVEAGKVA
HHHHHHHHHHHCCEE		44.1629967540
56UbiquitinationLQKVEAGKVAIKESH
HHHHHHCCEEEEHHH		35.2329967540
73UbiquitinationSTNLTHLRAIVESAE
CCCHHHHHHHHHHHC		18.0529967540
95UbiquitinationVLHVFGYTDTLGEKQ
HHHHHCCCCCCCCCE		23.9229967540
109UbiquitinationQTLVVDVVANGGHTW
EEEEEEEEECCCCHH		2.7229967540
114UbiquitinationDVVANGGHTWVKAIG
EEEECCCCHHHHHHH		20.2529967540
208PhosphorylationHPEELQPSESESDDE
CHHHHCCCCCCCCCC		40.5721082442
210PhosphorylationEELQPSESESDDEGP
HHHCCCCCCCCCCCC		46.8921082442
212PhosphorylationLQPSESESDDEGPEL
HCCCCCCCCCCCCCC		60.6921082442
223PhosphorylationGPELLQVTRVDRENI
CCCCEEEEEECCCCC		16.4128270605
233PhosphorylationDRENILASVAFPTEI
CCCCCEEEECCCCEE		15.5522210691
266PhosphorylationVSALSYGGCHFIFKE
HHHHHHCCCEEEEEH		8.0927251275
268PhosphorylationALSYGGCHFIFKEKV
HHHHCCCEEEEEHHH		23.3227251275
270PhosphorylationSYGGCHFIFKEKVLT
HHCCCEEEEEHHHHH		1.8327251275
299UbiquitinationLEAFMKDKELFACES
HHHHHCCHHHHHCHH		51.2929967540
309UbiquitinationFACESAVKDFQSILD
HHCHHHHHHHHHHHH		53.1729967540
353UbiquitinationLRLVASSKINSRSLT
HHHHHCCCCCCCEEE		43.3329967540
357UbiquitinationASSKINSRSLTIFGT
HCCCCCCCEEEEEEC		31.0629967540
367UbiquitinationTIFGTGDTLKAITMT
EEEECCCHHHEEEEE		31.3529967540
404UbiquitinationPRALTESKEALATPL
CCHHCCCHHHHCCCC		40.5524816145
411UbiquitinationKEALATPLPKDYTTD
HHHHCCCCCCCCCCC		7.7629967540
413UbiquitinationALATPLPKDYTTDSE
HHCCCCCCCCCCCCC		71.6729967540
415PhosphorylationATPLPKDYTTDSEH-
CCCCCCCCCCCCCC-		20.0526074081
416PhosphorylationTPLPKDYTTDSEH--
CCCCCCCCCCCCC--		33.9726074081
417PhosphorylationPLPKDYTTDSEH---
CCCCCCCCCCCC---		31.1627422710
418UbiquitinationLPKDYTTDSEH----
CCCCCCCCCCC----		44.2024816145
419PhosphorylationPKDYTTDSEH-----
CCCCCCCCCC-----		35.1626074081
462Ubiquitination------------------------------------------------
------------------------------------------------		24816145
471Ubiquitination---------------------------------------------------------
---------------------------------------------------------		29967540
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CG025_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CG025_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CG025_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FYN_HUMANFYNphysical
21900206
CEP70_HUMANCEP70physical
21900206
RL36L_HUMANRPL36ALphysical
21900206
CRYM_HUMANCRYMphysical
21900206
MTOR_HUMANMTORphysical
21900206
DACT1_HUMANDACT1physical
21900206
RASF1_HUMANRASSF1physical
21900206
HAP1_HUMANHAP1physical
21900206
UB2D1_HUMANUBE2D1physical
21900206
PTN_HUMANPTNphysical
21900206
SF3B2_HUMANSF3B2physical
21900206
EZH2_HUMANEZH2physical
21900206
NGEF_HUMANNGEFphysical
21900206
MYH14_HUMANMYH14physical
26186194
MUC5B_HUMANMUC5Bphysical
26186194
MUC5B_HUMANMUC5Bphysical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CG025_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-208; SER-210 ANDSER-212, AND MASS SPECTROMETRY.

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