MUC5B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MUC5B_HUMAN
• UniProt AC: Q9HC84
• Protein Name: Mucin-5B
• Gene Name: MUC5B
• Organism: Homo sapiens (Human).
• Sequence Length: 5762
• Subcellular Localization: Secreted.
• Protein Description: Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus..
• Protein Sequence: MGAPSACRTLVLALAAMLVVPQAETQGPVEPSWENAGHTMDGGAPTSSPTRRVSFVPPVTVFPSLSPLNPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPHSTTSPALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFENLRQRGYQVCPVLADIECRAAQLPDMPLEELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQAESFPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILHTYTHVDECGCTPFCVPAPMAPPHTRGFPAQEATAV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Phosphorylation	SSPTRRVSFVPPVTV CCCCCCEECCCCCEE	20.79	29802988
125	Phosphorylation	LRRGLVGSRPVVTRV HCCCCCCCCCEEEEE	26.40	-
130	Phosphorylation	VGSRPVVTRVVIKAQ CCCCCEEEEEEEEEC	20.27	-
144	Phosphorylation	QGLVLEASNGSVLIN CCEEEEECCCCEEEC	32.14	-
145	N-linked_Glycosylation	GLVLEASNGSVLING CEEEEECCCCEEECC	54.53	16740002
159	Phosphorylation	GQREELPYSRTGLLV CEECCCCCCCCCEEE	24.33	-
172	Phosphorylation	LVEQSGDYIKVSIRL EEEECCCEEEEEEEE	13.23	-
201	N-linked_Glycosylation	ELDPKYANQTCGLCG ECCHHHCCCCCCCCC	34.31	UniProtKB CARBOHYD
254	N-linked_Glycosylation	PLPLPAGNCTDEEGI CCCCCCCCCCCCCCC	27.85	16740002
401	N-linked_Glycosylation	YSPGTSFNTTCSSCT ECCCCCCCCCCCCCE	33.96	UniProtKB CARBOHYD
472	Phosphorylation	ELRKCGLTDNENCLK HHHHCCCCCCCCCEE	23.28	20562096
482	Phosphorylation	ENCLKAVTLSLDGGD CCCEEEEEEEECCCC	18.58	24667141
484	Phosphorylation	CLKAVTLSLDGGDTA CEEEEEEEECCCCEE	18.30	24667141
490	Phosphorylation	LSLDGGDTAIRVQAD EEECCCCEEEEEEEC	27.53	20562096
515	N-linked_Glycosylation	QLPLSAANITLFTPS CCCCCCCCEEEECCC	27.74	UniProtKB CARBOHYD
691	Phosphorylation	RDGVCTKYMQNCPKS CCCHHHHHHHHCCHH	5.93	29038488
805	N-linked_Glycosylation	MVYLDCSNSSAGTPG EEEEECCCCCCCCCH	46.44	UniProtKB CARBOHYD
929	N-linked_Glycosylation	AQDYCGDNTTHGTFR EECCCCCCCCCCEEE	31.96	UniProtKB CARBOHYD
953	Ubiquitination	TTGTTCSKAIKLFVE CCCCCHHHHHHHHHH	57.17	33845483
988	Phosphorylation	DPPYKIRYMGIFLVI CCCCEEEEEEEEEEE	11.81	24719451
1003	Phosphorylation	ETHGMAVSWDRKTSV EECCEEECCCCCCEE	17.45	24719451
1054	Phosphorylation	DALEFGNSWKLSPSC HHHHHCCCCCCCCCC	26.43	22985185
1203	Phosphorylation	CYPKCPPSQPFFNED CCCCCCCCCCCCCHH	35.31	24076635
1260	Phosphorylation	AHSLEACTCTYEDRT CCEEEEEECEECCCE	18.22	22468782
1276	N-linked_Glycosylation	SYQDVIYNTTDGLGA EEECEEEECCCCCCC	25.94	UniProtKB CARBOHYD
1292	N-linked_Glycosylation	LIAICGSNGTIIRKA EEEEECCCCCEEEEE	36.59	UniProtKB CARBOHYD
1340	C-linked_Glycosylation	CVREVCRWSSWYNGH HHHHHHCHHCCCCCC	7.50	-
1473	Phosphorylation	TTLWVTPSIRSTAAL EEEEECCCCCCHHEE	22.67	24719451
1482	Phosphorylation	RSTAALTSQTGSSSG CCHHEEECCCCCCCC	26.96	-
1509	C-linked_Glycosylation	TCQPRCQWTEWFDED CCCCCCCCCCCCCCC	10.42	-
1556	N-linked_Glycosylation	CQAESFPNWTLAQVG CCHHCCCCCCHHHHC	42.21	16740002
1647	Phosphorylation	TRAPPASTTAVPTLS CCCCCCCCCCCCCCC	22.38	-
1712	Phosphorylation	SLGTWRPSQPPTLAP CCCCCCCCCCCCCCC	46.90	22210691
1720	Phosphorylation	QPPTLAPTTMATSRA CCCCCCCCCCCCCCC	24.48	22210691
1721	Phosphorylation	PPTLAPTTMATSRAR CCCCCCCCCCCCCCC	12.07	22210691
1725	Phosphorylation	APTTMATSRARPTGT CCCCCCCCCCCCCCC	17.88	22210691
1743	Phosphorylation	ASKEPLTTSLAPTLT CCCCCCCCCCCHHHC	29.44	25332170
1750	Phosphorylation	TSLAPTLTSELSTSQ CCCCHHHCHHCCCCC	23.72	25332170
1754	Phosphorylation	PTLTSELSTSQAETS HHHCHHCCCCCCCCC	23.20	25332170
1774	N-linked_Glycosylation	TTMSPLTNTTTSQGT CCCCCCCCCCCCCCC	43.01	UniProtKB CARBOHYD
1775	Phosphorylation	TMSPLTNTTTSQGTT CCCCCCCCCCCCCCC	26.64	-
1790	C-linked_Glycosylation	RCQPKCEWTEWFDVD CCCCCCEEEEEEECC	14.75	-
1911	Phosphorylation	TWILTKPTTTATTTA EEEEECCCCEEEEEC	38.03	-
1912	Phosphorylation	WILTKPTTTATTTAS EEEECCCCEEEEECC	23.98	-
1913	Phosphorylation	ILTKPTTTATTTAST EEECCCCEEEEECCC	25.20	-
1915	Phosphorylation	TKPTTTATTTASTGS ECCCCEEEEECCCCC	23.69	-
1916	Phosphorylation	KPTTTATTTASTGST CCCCEEEEECCCCCC	20.21	-
1956	Phosphorylation	TSSKATPSSSPGTAT CCCCCCCCCCCCHHC	38.81	-
1957	Phosphorylation	SSKATPSSSPGTATA CCCCCCCCCCCHHCC	41.58	-
1958	Phosphorylation	SKATPSSSPGTATAL CCCCCCCCCCHHCCH	31.52	-
1963	O-linked_Glycosylation	SSSPGTATALPALRS CCCCCHHCCHHHHHC	28.68	OGP
1999	Phosphorylation	WTRLSQTTTPTATMS EEEECCCCCCCCEEE	24.12	-
2033	Phosphorylation	TATTTGATGSVATPS EEECCCCCCCEECCC	31.19	-
2035	Phosphorylation	TTTGATGSVATPSST ECCCCCCCEECCCCC	12.29	-
2038	Phosphorylation	GATGSVATPSSTPGT CCCCCEECCCCCCCC	22.88	-
2041	Phosphorylation	GSVATPSSTPGTAHT CCEECCCCCCCCCCC	39.56	-
2049	Phosphorylation	TPGTAHTTKVPTTTT CCCCCCCEECCCCEE	21.85	-
2064	Phosphorylation	TGFTATPSSSPGTAL CCEEECCCCCCCCCC	38.81	-
2066	Phosphorylation	FTATPSSSPGTALTP EEECCCCCCCCCCCC	31.52	-
2081	Phosphorylation	PVWISTTTTPTTRGS CEEEECCCCCCCCCC	30.76	-
2201	O-linked_Glycosylation	MATTHGRSLPPSSPH CCCCCCCCCCCCCCC	50.23	-
2201	Phosphorylation	MATTHGRSLPPSSPH CCCCCCCCCCCCCCC	50.23	-
2205	O-linked_Glycosylation	HGRSLPPSSPHTVRT CCCCCCCCCCCCHHH	55.34	-
2205	Phosphorylation	HGRSLPPSSPHTVRT CCCCCCCCCCCCHHH	55.34	27251275
2206	O-linked_Glycosylation	GRSLPPSSPHTVRTA CCCCCCCCCCCHHHH	26.86	-
2206	Phosphorylation	GRSLPPSSPHTVRTA CCCCCCCCCCCHHHH	26.86	27251275
2209	O-linked_Glycosylation	LPPSSPHTVRTAWTS CCCCCCCCHHHHHHH	18.31	-
2209	Phosphorylation	LPPSSPHTVRTAWTS CCCCCCCCHHHHHHH	18.31	27251275
2264	Phosphorylation	PSSRTTESPPSPGTT CCCCCCCCCCCCCCC	39.76	22496350
2267	Phosphorylation	RTTESPPSPGTTTPG CCCCCCCCCCCCCCC	39.07	-
2270	Phosphorylation	ESPPSPGTTTPGHTT CCCCCCCCCCCCCCC	30.77	30576142
2271	Phosphorylation	SPPSPGTTTPGHTTA CCCCCCCCCCCCCCC	36.59	-
2277	Phosphorylation	TTTPGHTTATSRTTA CCCCCCCCCCCCCCC	23.43	30576142
2279	Phosphorylation	TPGHTTATSRTTATA CCCCCCCCCCCCCEE	19.35	30576142
2282	Phosphorylation	HTTATSRTTATATPS CCCCCCCCCCEECCC	22.13	-
2283	Phosphorylation	TTATSRTTATATPSK CCCCCCCCCEECCCC	22.39	-
2285	Phosphorylation	ATSRTTATATPSKTR CCCCCCCEECCCCCC	29.04	-
2289	Phosphorylation	TTATATPSKTRTSTL CCCEECCCCCCCCCC	42.16	-
2291	Phosphorylation	ATATPSKTRTSTLLP CEECCCCCCCCCCCC	43.44	-
2320	C-linked_Glycosylation	GCEPQCAWSEWLDYS CCCCCCCHHHHEEEC	12.38	-
2531	Phosphorylation	ALRSTATTPTATSFT HHHCCCCCCCCCEEE	19.04	-
2542	Phosphorylation	TSFTAIPSSSLGTTW CEEEEECCCCCCCCE	26.84	-
2556	Phosphorylation	WTRLSQTTTPTATMS EEEECCCCCCCCEEE	24.12	-
2590	Phosphorylation	TATTTGATGSVATPS EECCCCCCCCEECCC	31.19	-
2592	Phosphorylation	TTTGATGSVATPSST CCCCCCCCEECCCCC	12.29	-
2595	Phosphorylation	GATGSVATPSSTPGT CCCCCEECCCCCCCC	22.88	-
2598	Phosphorylation	GSVATPSSTPGTAHT CCEECCCCCCCCCEE	39.56	-
2606	Phosphorylation	TPGTAHTTKVLTTTT CCCCCEEEEEEEEEC	14.86	-
2638	Phosphorylation	PVWISTTTTPTTRGS EEEEECCCCCCCCCC	30.76	-
2749	N-linked_Glycosylation	THTPPVPNTTATTHG CCCCCCCCCCCCCCC	50.74	-
2758	O-linked_Glycosylation	TATTHGRSLSPSSPH CCCCCCCCCCCCCCC	37.48	-
2758	Phosphorylation	TATTHGRSLSPSSPH CCCCCCCCCCCCCCC	37.48	23312004
2760	O-linked_Glycosylation	TTHGRSLSPSSPHTV CCCCCCCCCCCCCCC	24.79	-
2760	Phosphorylation	TTHGRSLSPSSPHTV CCCCCCCCCCCCCCC	24.79	28348404
2762	O-linked_Glycosylation	HGRSLSPSSPHTVRT CCCCCCCCCCCCCEE	53.80	-
2762	Phosphorylation	HGRSLSPSSPHTVRT CCCCCCCCCCCCCEE	53.80	28348404
2763	O-linked_Glycosylation	GRSLSPSSPHTVRTA CCCCCCCCCCCCEEE	24.88	-
2763	Phosphorylation	GRSLSPSSPHTVRTA CCCCCCCCCCCCEEE	24.88	23312004
2766	O-linked_Glycosylation	LSPSSPHTVRTAWTS CCCCCCCCCEEEEEE	18.31	-
2766	Phosphorylation	LSPSSPHTVRTAWTS CCCCCCCCCEEEEEE	18.31	23312004
2821	Phosphorylation	PSSRTTESPPSPGTT CCCCCCCCCCCCCCC	39.76	22496350
2824	Phosphorylation	RTTESPPSPGTTTPG CCCCCCCCCCCCCCC	39.07	-
2839	Phosphorylation	HTRATSRTTATATPS CCCCCCCCCCEECCC	22.13	-
2840	Phosphorylation	TRATSRTTATATPSK CCCCCCCCCEECCCC	22.39	-
2842	Phosphorylation	ATSRTTATATPSKTR CCCCCCCEECCCCCC	29.04	-
2846	Phosphorylation	TTATATPSKTRTSTL CCCEECCCCCCCCCC	42.16	-
2848	Phosphorylation	ATATPSKTRTSTLLP CEECCCCCCCCCCCC	43.44	-
2877	C-linked_Glycosylation	GCEPQCAWSEWLDYS CCCCCCCHHHHEEEC	12.38	-
3001	Phosphorylation	TEQTTAATTTATTGS ECCCCCCEEECCCCC	23.40	-
3014	Phosphorylation	GSTAIPSSTPGTAPP CCCCCCCCCCCCCCC	33.01	-
3030	Phosphorylation	KVLTSTATTPTATSS EEEEEEECCCCCCCC	33.14	-
3036	Phosphorylation	ATTPTATSSKATSSS ECCCCCCCCCCCCCC	27.64	-
3041	Phosphorylation	ATSSKATSSSSPRTA CCCCCCCCCCCCCCC	32.84	-
3042	Phosphorylation	TSSKATSSSSPRTAT CCCCCCCCCCCCCCC	30.40	-
3043	Phosphorylation	SSKATSSSSPRTATT CCCCCCCCCCCCCCC	44.09	-
3044	Phosphorylation	SKATSSSSPRTATTL CCCCCCCCCCCCCCC	21.98	-
3050	Phosphorylation	SSPRTATTLPVLTST CCCCCCCCCCEEEEC	26.97	-
3059	Phosphorylation	PVLTSTATKSTATSF CEEEECCCCCCCCCC	26.14	-
3061	Phosphorylation	LTSTATKSTATSFTP EEECCCCCCCCCCCC	20.94	-
3092	Phosphorylation	TTPMATMSTIHPSST CCCCEEECCCCCCCC	21.61	-
3099	Phosphorylation	STIHPSSTPETTHTS CCCCCCCCCCCCCCC	29.49	-
3207	Phosphorylation	ATTPTVISSRATPSS CCCCEEEECCCCCCC	14.94	-
3208	Phosphorylation	TTPTVISSRATPSSS CCCEEEECCCCCCCC	18.14	24719451
3213	Phosphorylation	ISSRATPSSSPGTAT EECCCCCCCCCCHHC	38.81	-
3214	Phosphorylation	SSRATPSSSPGTATA ECCCCCCCCCCHHCH	41.58	-
3256	Phosphorylation	WTRLSQTTTPTATMS HHHCCCCCCCCCEEC	24.12	-
3290	Phosphorylation	TTTTTRATGSVATPS ECCEECCCCCEECCC	27.05	-
3292	Phosphorylation	TTTRATGSVATPSST CEECCCCCEECCCCC	12.29	-
3295	Phosphorylation	RATGSVATPSSTPGT CCCCCEECCCCCCCC	22.88	-
3298	Phosphorylation	GSVATPSSTPGTAHT CCEECCCCCCCCCCC	39.56	-
3306	Phosphorylation	TPGTAHTTKVPTTTT CCCCCCCEECCCCEE	21.85	-
3321	Phosphorylation	TGFTATPSSSPGTAL CCEEECCCCCCCCCC	38.81	-
3323	Phosphorylation	FTATPSSSPGTALTP EEECCCCCCCCCCCC	31.52	-
3338	Phosphorylation	PVWISTTTTPTTRGS CEEEECCCCCCCCCC	30.76	-
3449	N-linked_Glycosylation	THTPPVPNTTATTHG CCCCCCCCCCCCCCC	50.74	UniProtKB CARBOHYD
3458	O-linked_Glycosylation	TATTHGRSLPPSSPH CCCCCCCCCCCCCCC	50.23	-
3462	O-linked_Glycosylation	HGRSLPPSSPHTVRT CCCCCCCCCCCCHHH	55.34	-
3462	Phosphorylation	HGRSLPPSSPHTVRT CCCCCCCCCCCCHHH	55.34	27251275
3463	O-linked_Glycosylation	GRSLPPSSPHTVRTA CCCCCCCCCCCHHHH	26.86	-
3463	Phosphorylation	GRSLPPSSPHTVRTA CCCCCCCCCCCHHHH	26.86	27251275
3466	O-linked_Glycosylation	LPPSSPHTVRTAWTS CCCCCCCCHHHHHHH	18.31	-
3466	Phosphorylation	LPPSSPHTVRTAWTS CCCCCCCCHHHHHHH	18.31	27251275
3521	Phosphorylation	PSSRTTESPPSPGTT CCCCCCCCCCCCCCC	39.76	22496350
3524	Phosphorylation	RTTESPPSPGTTTPG CCCCCCCCCCCCCCC	39.07	-
3528	Phosphorylation	SPPSPGTTTPGHTRG CCCCCCCCCCCCCCC	36.59	-
3536	Phosphorylation	TPGHTRGTSRTTATA CCCCCCCCCCCCCCC	16.25	-
3546	Phosphorylation	TTATATPSKTRTSTL CCCCCCCCCCCCCCC	42.16	-
3548	Phosphorylation	ATATPSKTRTSTLLP CCCCCCCCCCCCCCC	43.44	-
3577	C-linked_Glycosylation	GCEPQCAWSEWLDYS CCCCCCCHHHHEEEC	12.38	-
3788	Phosphorylation	ALRSTATTPTATSFT HHHCCCCCCCCCEEE	19.04	-
3799	Phosphorylation	TSFTAIPSSSLGTTW CEEEEECCCCCCCCE	26.84	-
3813	Phosphorylation	WTRLSQTTTPTATMS EEEECCCCCCCCEEE	24.12	-
3847	Phosphorylation	TATTTRATGSVATPS EECCCCCCCCEECCC	27.05	-
3849	Phosphorylation	TTTRATGSVATPSST CCCCCCCCEECCCCC	12.29	-
3852	Phosphorylation	RATGSVATPSSTPGT CCCCCEECCCCCCCC	22.88	-
3855	Phosphorylation	GSVATPSSTPGTAHT CCEECCCCCCCCCCC	39.56	-
3863	Phosphorylation	TPGTAHTTKVPTTTT CCCCCCCEECCCEEE	21.85	-
4006	N-linked_Glycosylation	THTPPVPNTTATTHG CCCCCCCCCCCCCCC	50.74	-
4015	O-linked_Glycosylation	TATTHGRSLSPSSPH CCCCCCCCCCCCCCC	37.48	-
4015	Phosphorylation	TATTHGRSLSPSSPH CCCCCCCCCCCCCCC	37.48	23312004
4017	O-linked_Glycosylation	TTHGRSLSPSSPHTV CCCCCCCCCCCCCCC	24.79	-
4017	Phosphorylation	TTHGRSLSPSSPHTV CCCCCCCCCCCCCCC	24.79	28348404
4019	O-linked_Glycosylation	HGRSLSPSSPHTVRT CCCCCCCCCCCCCEE	53.80	-
4019	Phosphorylation	HGRSLSPSSPHTVRT CCCCCCCCCCCCCEE	53.80	28348404
4020	O-linked_Glycosylation	GRSLSPSSPHTVRTA CCCCCCCCCCCCEEE	24.88	-
4020	Phosphorylation	GRSLSPSSPHTVRTA CCCCCCCCCCCCEEE	24.88	23312004
4023	O-linked_Glycosylation	LSPSSPHTVRTAWTS CCCCCCCCCEEEEEE	18.31	-
4023	Phosphorylation	LSPSSPHTVRTAWTS CCCCCCCCCEEEEEE	18.31	23312004
4078	Phosphorylation	PSSRTTESPPSPGTT CCCCCCCCCCCCCCC	39.76	22496350
4081	Phosphorylation	RTTESPPSPGTTTPG CCCCCCCCCCCCCCC	39.07	-
4084	Phosphorylation	ESPPSPGTTTPGHTT CCCCCCCCCCCCCCC	30.77	30576142
4085	Phosphorylation	SPPSPGTTTPGHTTA CCCCCCCCCCCCCCC	36.59	-
4091	Phosphorylation	TTTPGHTTATSRTTA CCCCCCCCCCCCCCC	23.43	30576142
4093	Phosphorylation	TPGHTTATSRTTATA CCCCCCCCCCCCCEE	19.35	30576142
4096	Phosphorylation	HTTATSRTTATATPS CCCCCCCCCCEECCC	22.13	-
4097	Phosphorylation	TTATSRTTATATPSK CCCCCCCCCEECCCC	22.39	-
4099	Phosphorylation	ATSRTTATATPSKTR CCCCCCCEECCCCCC	29.04	-
4103	Phosphorylation	TTATATPSKTRTSTL CCCEECCCCCCCCCC	42.16	-
4105	Phosphorylation	ATATPSKTRTSTLLP CEECCCCCCCCCCCC	43.44	-
4134	C-linked_Glycosylation	GCEPQCAWSEWLDYS CCCCCCCHHHHEEEC	12.38	-
4283	Phosphorylation	APPPKVLTSPATTPT CCCCCEECCCCCCCC	35.33	-
4284	Phosphorylation	PPPKVLTSPATTPTA CCCCEECCCCCCCCC	14.37	-
4288	Phosphorylation	VLTSPATTPTATSSK EECCCCCCCCCCCCC	22.28	-
4293	Phosphorylation	ATTPTATSSKATSSS CCCCCCCCCCCCCCC	27.64	-
4298	Phosphorylation	ATSSKATSSSSPRTA CCCCCCCCCCCCCCC	32.84	-
4299	Phosphorylation	TSSKATSSSSPRTAT CCCCCCCCCCCCCCC	30.40	-
4300	Phosphorylation	SSKATSSSSPRTATT CCCCCCCCCCCCCCC	44.09	-
4301	Phosphorylation	SKATSSSSPRTATTL CCCCCCCCCCCCCCC	21.98	-
4307	Phosphorylation	SSPRTATTLPVLTST CCCCCCCCCCEEECC	26.97	-
4316	Phosphorylation	PVLTSTATKSTATSV CEEECCCCCCCCCCC	26.14	-
4318	Phosphorylation	LTSTATKSTATSVTP EECCCCCCCCCCCCC	20.94	-
4343	Phosphorylation	TLPEQTTTPVATMST CCCCCCCCCEEEEEE	21.10	30576142
4347	Phosphorylation	QTTTPVATMSTIHPS CCCCCEEEEEEECCC	16.34	-
4349	Phosphorylation	TTPVATMSTIHPSST CCCEEEEEEECCCCC	21.61	-
4356	Phosphorylation	STIHPSSTPETTHTS EEECCCCCCCCCCEE	29.49	-
4362	Phosphorylation	STPETTHTSTVLTTK CCCCCCCEEEEEEEC	24.81	30576142
4368	Phosphorylation	HTSTVLTTKATTTRA CEEEEEEECEEECCC	17.96	30576142
4498	Phosphorylation	TSSKATPSSSPGTAT ECCCCCCCCCCCHHC	38.81	-
4499	Phosphorylation	SSKATPSSSPGTATA CCCCCCCCCCCHHCC	41.58	-
4500	Phosphorylation	SKATPSSSPGTATAL CCCCCCCCCCHHCCH	31.52	-
4516	Phosphorylation	ALRSTATTPTATSFT HHHCCCCCCCCCEEE	19.04	-
4527	Phosphorylation	TSFTAIPSSSLGTTW CEEEEECCCCCCCCE	26.84	-
4541	Phosphorylation	WTRLSQTTTPTATMS EEEECCCCCCCCEEE	24.12	-
4575	Phosphorylation	TATTTGATGSVATPS EEECCCCCCCEECCC	31.19	-
4577	Phosphorylation	TTTGATGSVATPSST ECCCCCCCEECCCCC	12.29	-
4580	Phosphorylation	GATGSVATPSSTPGT CCCCCEECCCCCCCC	22.88	-
4583	Phosphorylation	GSVATPSSTPGTAHT CCEECCCCCCCCCCC	39.56	-
4591	Phosphorylation	TPGTAHTTKVPTTTT CCCCCCCEECCCCEE	21.85	-
4606	Phosphorylation	TGFTATPSSSPGTAL CCEEECCCCCCCCCC	38.81	-
4608	Phosphorylation	FTATPSSSPGTALTP EEECCCCCCCCCCCC	31.52	-
4725	Phosphorylation	ATSSKATSSSSPRTA CCCCCCCCCCCCCCC	32.84	-
4726	Phosphorylation	TSSKATSSSSPRTAT CCCCCCCCCCCCCCC	30.40	-
4727	Phosphorylation	SSKATSSSSPRTATT CCCCCCCCCCCCCCC	44.09	-
4728	Phosphorylation	SKATSSSSPRTATTL CCCCCCCCCCCCCCC	21.98	-
4734	Phosphorylation	SSPRTATTLPVLTST CCCCCCCCCCEEEEC	26.97	-
4743	Phosphorylation	PVLTSTATKSTATSF CEEEECCCCCCCCCC	26.14	-
4745	Phosphorylation	LTSTATKSTATSFTP EEECCCCCCCCCCCC	20.94	-
4804	N-linked_Glycosylation	ATMTRATNSTATPSS EEEEECCCCCCCCCC	36.06	UniProtKB CARBOHYD
4869	Phosphorylation	GSTATASSTLGTAHT CCCCCCCCCCCCCCC	25.78	21299198
4960	N-linked_Glycosylation	SPGEVIYNKTDRAGC CCCCEEECCCCCCCC	29.62	16740002
5017	N-linked_Glycosylation	AIPLRQVNETWTLEN CCCHHCCCCCEEEEC	32.42	16740002
5024	N-linked_Glycosylation	NETWTLENCTVARCV CCCEEEECCEEEEEE	29.85	16740002
5046	N-linked_Glycosylation	LDPKPVANVTCVNKH ECCCCCCEEEEECCC	29.84	16740002
5096	N-linked_Glycosylation	TSYTFRGNCTYVLMR CCEEECCCEEEEEEE	15.65	16740002
5111	N-linked_Glycosylation	EIHARFGNLSLYLDN HHHHHHCCEEEEECC	24.60	16740002
5142	Phosphorylation	ALSIHYKSMDIVLTV EEEEEEECCCEEEEE	17.96	-
5172	Phosphorylation	IPVSSGFSKNGVLVS EECCCCCCCCCEEEE	28.83	23403867
5215	N-linked_Glycosylation	LPYSLFHNNTEGQCG CCEEECCCCCCCCCC	50.19	16740002
5441	Phosphorylation	SCVCDEGSVSVQCKP CEEECCCCEEEEEEE	14.79	30631047
5486	N-linked_Glycosylation	PETVCVCNTTTCPQS CCCEEEECCCCCCCC	21.77	UniProtKB CARBOHYD
5526	N-linked_Glycosylation	RPQLCSYNGTFYGVG CCCEECCCCEEEECC	27.08	UniProtKB CARBOHYD
5565	N-linked_Glycosylation	QCQEDACNNTTCPQG CCCCCCCCCCCCCCC	51.07	UniProtKB CARBOHYD
5566	N-linked_Glycosylation	CQEDACNNTTCPQGF CCCCCCCCCCCCCCC	36.33	UniProtKB CARBOHYD
5602	N-linked_Glycosylation	DGQPVQLNETWVNSH CCCEEECCCCEECCC	27.79	UniProtKB CARBOHYD
5612	N-linked_Glycosylation	WVNSHVDNCTVYLCE EECCCCCCEEEEEEE	23.44	UniProtKB CARBOHYD
5647	Phosphorylation	CRGSLRKTGCCYSCE CCCCCCCCCCCEECC	29.08	24114839
5651	Phosphorylation	LRKTGCCYSCEEDSC CCCCCCCEECCCCCE	22.04	24114839
5652	Phosphorylation	RKTGCCYSCEEDSCQ CCCCCCEECCCCCEE	10.92	24114839
5657	Phosphorylation	CYSCEEDSCQVRINT CEECCCCCEEEEEEC	15.10	24114839
5663	N-linked_Glycosylation	DSCQVRINTTILWHQ CCEEEEEECEEEEEC	22.17	UniProtKB CARBOHYD
5677	N-linked_Glycosylation	QGCETEVNITFCEGS CCCCEEEEEEEECCC	22.73	UniProtKB CARBOHYD
5692	Phosphorylation	CPGASKYSAEAQAMQ CCCCCHHHHHHHHHH	24.30	29038488
5721	N-linked_Glycosylation	TVPLHCPNGSAILHT CCCEECCCCCEEEEE	63.55	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MUC5B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MUC5B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
144	Phosphorylation	148 (4)	V ⇒ I	rs56293203	Major depressive disorder	27777418
145	N-linked Glycosylation	148 (3)	V ⇒ I	rs56293203	Major depressive disorder	27777418

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AMY1_HUMAN	AMY1A	physical	9109822
STAT_HUMAN	STATH	physical	9109822
HIS1_HUMAN	HTN1	physical	9109822

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 178500: Pulmonary fibrosis, idiopathic (IPF)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

N-linked Glycosylation

"Identification of N-linked glycoproteins in human saliva byglycoprotein capture and mass spectrometry.";
Ramachandran P., Boontheung P., Xie Y., Sondej M., Wong D.T.,Loo J.A.;
J. Proteome Res. 5:1493-1503(2006).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-145; ASN-254; ASN-1556;ASN-4960; ASN-5017; ASN-5024; ASN-5046; ASN-5096; ASN-5111 ANDASN-5215, AND MASS SPECTROMETRY.
PubMed: 16740002