dbPTM

E41L2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	E41L2_HUMAN
UniProt AC	O43491
Protein Name	Band 4.1-like protein 2
Gene Name	EPB41L2
Organism	Homo sapiens (Human).
Sequence Length	1005
Subcellular Localization	Cytoplasm, cytoskeleton. Cytoplasm, cell cortex . Cell membrane .
Protein Description	Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. [PubMed: 23870127]
Protein Sequence	MTTEVGSVSEVKKDSSQLGTDATKEKPKEVAENQQNQSSDPEEEKGSQPPPAAESQSSLRRQKREKETSESRGISRFIPPWLKKQKSYTLVVAKDGGDKKEPTQAVVEEQVLDKEEPLPEEQRQAKGDAEEMAQKKQEIKVEVKEEKPSVSKEEKPSVSKVEMQPTELVSKEREEKVKETQEDKLEGGAAKRETKEVQTNELKAEKASQKVTKKTKTVQCKVTLLDGTEYSCDLEKHAKGQVLFDKVCEHLNLLEKDYFGLLFQESPEQKNWLDPAKEIKRQLRNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAELGDYDPEEHGSIDLSEFQFAPTQTKELEEKVAELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKAKFLTLGSKFRYSGRTQAQTRQASTLIDRPAPHFERTSSKRVSRSLDGAPIGVMDQSLMKDFPGAAGEISAYGPGLVSIAVVQDGDGRREVRSPTKAPHLQLIEGKKNSLRVEGDNIYVRHSNLMLEELDKAQEDILKHQASISELKRNFMESTPEPRPNEWEKRRITPLSLQTQGSSHETLNIVEEKKRAEVGKDERVITEEMNGKEISPGSGPGEIRKVEPVTQKDSTSLSSESSSSSSESEEEDVGEYRPHHRVTEGTIREEQEYEEEVEEEPRPAAKVVEREEAVPEASPVTQAGASVITVETVIQENVGAQKIPGEKSVHEGALKQDMGEEAEEEPQKVNGEVSHVDIDVLPQIICCSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGTLLTAQTITSESVSTTTTTHITKTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGED

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MTTEVGSVS ------CCCCCCCHH	42.86	22223895
2	Phosphorylation	------MTTEVGSVS ------CCCCCCCHH	42.86	28450419
3	Phosphorylation	-----MTTEVGSVSE -----CCCCCCCHHH	40.30	28450419
7	Phosphorylation	-MTTEVGSVSEVKKD -CCCCCCCHHHCCCC	27.87	29255136
9	Phosphorylation	TTEVGSVSEVKKDSS CCCCCCHHHCCCCHH	38.07	28450419
12	2-Hydroxyisobutyrylation	VGSVSEVKKDSSQLG CCCHHHCCCCHHHCC	46.97	-
12	Ubiquitination	VGSVSEVKKDSSQLG CCCHHHCCCCHHHCC	46.97	-
13	Ubiquitination	GSVSEVKKDSSQLGT CCHHHCCCCHHHCCC	68.93	21890473
15	Phosphorylation	VSEVKKDSSQLGTDA HHHCCCCHHHCCCCC	28.94	26657352
16	Phosphorylation	SEVKKDSSQLGTDAT HHCCCCHHHCCCCCC	39.29	21815630
20	Phosphorylation	KDSSQLGTDATKEKP CCHHHCCCCCCCHHH	30.93	28450419
23	O-linked_Glycosylation	SQLGTDATKEKPKEV HHCCCCCCCHHHHHH	42.41	23301498
23	Phosphorylation	SQLGTDATKEKPKEV HHCCCCCCCHHHHHH	42.41	30576142
24	Ubiquitination	QLGTDATKEKPKEVA HCCCCCCCHHHHHHH	66.51	-
28	Ubiquitination	DATKEKPKEVAENQQ CCCCHHHHHHHHHHC	75.73	21890473
38	Phosphorylation	AENQQNQSSDPEEEK HHHHCCCCCCHHHHC	44.23	29255136
39	Phosphorylation	ENQQNQSSDPEEEKG HHHCCCCCCHHHHCC	47.63	29255136
45	Ubiquitination	SSDPEEEKGSQPPPA CCCHHHHCCCCCCCH	68.11	21890473
47	Phosphorylation	DPEEEKGSQPPPAAE CHHHHCCCCCCCHHH	51.05	17525332
55	Phosphorylation	QPPPAAESQSSLRRQ CCCCHHHCHHHHHHH	30.54	29255136
57	Phosphorylation	PPAAESQSSLRRQKR CCHHHCHHHHHHHHH	40.39	29255136
58	Phosphorylation	PAAESQSSLRRQKRE CHHHCHHHHHHHHHH	20.47	29255136
72	Methylation	EKETSESRGISRFIP HHHHHHHCCCHHCCC	42.27	-
83	Methylation	RFIPPWLKKQKSYTL HCCCHHHHCCCEEEE	49.65	-
83	Ubiquitination	RFIPPWLKKQKSYTL HCCCHHHHCCCEEEE	49.65	-
84	Ubiquitination	FIPPWLKKQKSYTLV CCCHHHHCCCEEEEE	61.87	-
86	Ubiquitination	PPWLKKQKSYTLVVA CHHHHCCCEEEEEEE	55.07	-
87	Phosphorylation	PWLKKQKSYTLVVAK HHHHCCCEEEEEEEE	22.36	25159151
88	Phosphorylation	WLKKQKSYTLVVAKD HHHCCCEEEEEEEEC	15.89	25159151
89	Phosphorylation	LKKQKSYTLVVAKDG HHCCCEEEEEEEECC	21.84	22167270
94	Acetylation	SYTLVVAKDGGDKKE EEEEEEEECCCCCCC	45.34	19809279
94	Ubiquitination	SYTLVVAKDGGDKKE EEEEEEEECCCCCCC	45.34	-
99	Acetylation	VAKDGGDKKEPTQAV EEECCCCCCCCCCHH	63.41	19809289
99	Ubiquitination	VAKDGGDKKEPTQAV EEECCCCCCCCCCHH	63.41	21890473
100	Ubiquitination	AKDGGDKKEPTQAVV EECCCCCCCCCCHHH	73.91	21890473
103	Phosphorylation	GGDKKEPTQAVVEEQ CCCCCCCCCHHHHHH	30.19	23312004
114	Ubiquitination	VEEQVLDKEEPLPEE HHHHHCCCCCCCCHH	60.87	21890473
126	Ubiquitination	PEEQRQAKGDAEEMA CHHHHHHHCCHHHHH	49.32	21890473
132	Sulfoxidation	AKGDAEEMAQKKQEI HHCCHHHHHHHHHHH	3.44	30846556
135	Acetylation	DAEEMAQKKQEIKVE CHHHHHHHHHHHEEE	47.05	25953088
135	Ubiquitination	DAEEMAQKKQEIKVE CHHHHHHHHHHHEEE	47.05	21890473
140	Sumoylation	AQKKQEIKVEVKEEK HHHHHHHEEEEECCC	31.43	28112733
140	Ubiquitination	AQKKQEIKVEVKEEK HHHHHHHEEEEECCC	31.43	-
144	Sumoylation	QEIKVEVKEEKPSVS HHHEEEEECCCCCCC	46.80	28112733
144	Ubiquitination	QEIKVEVKEEKPSVS HHHEEEEECCCCCCC	46.80	21890473
149	Phosphorylation	EVKEEKPSVSKEEKP EEECCCCCCCCCCCC	50.52	26074081
151	Phosphorylation	KEEKPSVSKEEKPSV ECCCCCCCCCCCCCC	38.39	26074081
157	Phosphorylation	VSKEEKPSVSKVEMQ CCCCCCCCCCEEECC	50.52	28857561
159	Phosphorylation	KEEKPSVSKVEMQPT CCCCCCCCEEECCHH	35.01	28857561
160	Ubiquitination	EEKPSVSKVEMQPTE CCCCCCCEEECCHHH	39.81	21890473
163	Sulfoxidation	PSVSKVEMQPTELVS CCCCEEECCHHHHHC	6.91	21406390
166	Phosphorylation	SKVEMQPTELVSKER CEEECCHHHHHCHHH	25.67	29523821
170	Phosphorylation	MQPTELVSKEREEKV CCHHHHHCHHHHHHH	41.23	25850435
171	Acetylation	QPTELVSKEREEKVK CHHHHHCHHHHHHHH	54.00	7706837
171	Ubiquitination	QPTELVSKEREEKVK CHHHHHCHHHHHHHH	54.00	21890473
176	Acetylation	VSKEREEKVKETQED HCHHHHHHHHHHHHH	54.58	20167786
178	Ubiquitination	KEREEKVKETQEDKL HHHHHHHHHHHHHHH	67.14	21890473
180	Phosphorylation	REEKVKETQEDKLEG HHHHHHHHHHHHHCC	31.38	29214152
184	Acetylation	VKETQEDKLEGGAAK HHHHHHHHHCCCCCC	47.92	20167786
184	Ubiquitination	VKETQEDKLEGGAAK HHHHHHHHHCCCCCC	47.92	21890473
191	Acetylation	KLEGGAAKRETKEVQ HHCCCCCCCCCCHHH	50.67	20167786
194	Phosphorylation	GGAAKRETKEVQTNE CCCCCCCCCHHHHHH	36.22	29214152
195	Ubiquitination	GAAKRETKEVQTNEL CCCCCCCCHHHHHHH	51.65	21890473
199	Phosphorylation	RETKEVQTNELKAEK CCCCHHHHHHHHHHH	35.52	23312004
203	Ubiquitination	EVQTNELKAEKASQK HHHHHHHHHHHHHHH	48.60	21890473
206	Ubiquitination	TNELKAEKASQKVTK HHHHHHHHHHHHCCC	59.19	-
208	Phosphorylation	ELKAEKASQKVTKKT HHHHHHHHHHCCCCC	41.42	22817900
212	Phosphorylation	EKASQKVTKKTKTVQ HHHHHHCCCCCCEEE	33.58	23312004
221	Ubiquitination	KTKTVQCKVTLLDGT CCCEEEEEEEECCCC	22.59	-
232	Glutathionylation	LDGTEYSCDLEKHAK CCCCEEECCCHHHCC	7.29	22555962
239	2-Hydroxyisobutyrylation	CDLEKHAKGQVLFDK CCCHHHCCCCHHHHH	49.98	-
239	Ubiquitination	CDLEKHAKGQVLFDK CCCHHHCCCCHHHHH	49.98	-
246	Ubiquitination	KGQVLFDKVCEHLNL CCCHHHHHHHHHHCH	41.26	21890473
266	Phosphorylation	FGLLFQESPEQKNWL HHHHCCCCHHHCCCC	23.97	-
270	Ubiquitination	FQESPEQKNWLDPAK CCCCHHHCCCCCHHH	48.72	21890473
291	Phosphorylation	RNLPWLFTFNVKFYP HCCCEEEEEEEEECC	16.48	20068231
297	Phosphorylation	FTFNVKFYPPDPSQL EEEEEEECCCCHHHC	14.24	20068231
302	Phosphorylation	KFYPPDPSQLTEDIT EECCCCHHHCCHHHH	45.24	20068231
305	Phosphorylation	PPDPSQLTEDITRYF CCCHHHCCHHHHHHH	24.79	20068231
309	Phosphorylation	SQLTEDITRYFLCLQ HHCCHHHHHHHHHHH	31.47	20068231
369	Ubiquitination	QFAPTQTKELEEKVA EECCCCHHHHHHHHH	50.95	-
374	Acetylation	QTKELEEKVAELHKT CHHHHHHHHHHHHHH	37.05	23236377
374	Ubiquitination	QTKELEEKVAELHKT CHHHHHHHHHHHHHH	37.05	21890473
380	Ubiquitination	EKVAELHKTHRGLSP HHHHHHHHHCCCCCH	59.66	-
386	Phosphorylation	HKTHRGLSPAQADSQ HHHCCCCCHHHHHHH	22.48	23401153
399	2-Hydroxyisobutyrylation	SQFLENAKRLSMYGV HHHHHHHHHHHHHCC	66.51	-
399	Ubiquitination	SQFLENAKRLSMYGV HHHHHHHHHHHHHCC	66.51	21890473
402	Phosphorylation	LENAKRLSMYGVDLH HHHHHHHHHHCCCCH	17.62	30108239
404	Phosphorylation	NAKRLSMYGVDLHHA HHHHHHHHCCCCHHC	15.60	29214152
444	Ubiquitination	INRFAWPKILKISYK CCCCHHHEEEEEEEE	50.39	21890473
449	Phosphorylation	WPKILKISYKRSNFY HHEEEEEEEECCCEE	24.02	20068231
450	Phosphorylation	PKILKISYKRSNFYI HEEEEEEEECCCEEE	17.56	20068231
474	Ubiquitination	FESTIGFKLPNHRAA HHHHHCCCCCCHHHH	58.80	21890473
493	Phosphorylation	KVCVEHHTFYRLVSP HHHHHHCCEEEECCC	25.03	30301811
495	Phosphorylation	CVEHHTFYRLVSPEQ HHHHCCEEEECCCCC	12.28	30301811
499	Phosphorylation	HTFYRLVSPEQPPKA CCEEEECCCCCCCCC	27.58	30266825
505	Ubiquitination	VSPEQPPKAKFLTLG CCCCCCCCCEEEECC	71.53	-
507	Ubiquitination	PEQPPKAKFLTLGSK CCCCCCCEEEECCCC	47.21	-
510	Phosphorylation	PPKAKFLTLGSKFRY CCCCEEEECCCCCCC	32.00	23911959
513	Phosphorylation	AKFLTLGSKFRYSGR CEEEECCCCCCCCCC	31.56	23403867
514	Ubiquitination	KFLTLGSKFRYSGRT EEEECCCCCCCCCCC	31.87	21890473
514	Acetylation	KFLTLGSKFRYSGRT EEEECCCCCCCCCCC	31.87	19608861
514	Ubiquitination	KFLTLGSKFRYSGRT EEEECCCCCCCCCCC	31.87	21906983
514	Ubiquitination	KFLTLGSKFRYSGRT EEEECCCCCCCCCCC	31.87	21890473
517	Phosphorylation	TLGSKFRYSGRTQAQ ECCCCCCCCCCCHHC	20.71	20873877
518	Phosphorylation	LGSKFRYSGRTQAQT CCCCCCCCCCCHHCH	19.97	28355574
529	Phosphorylation	QAQTRQASTLIDRPA HHCHHCHHHHCCCCC	18.53	27273156
530	Phosphorylation	AQTRQASTLIDRPAP HCHHCHHHHCCCCCC	30.65	20068231
534	Methylation	QASTLIDRPAPHFER CHHHHCCCCCCCCCC	23.45	-
548	Phosphorylation	RTSSKRVSRSLDGAP CCCCCHHHHCCCCCC	21.86	23401153
550	Phosphorylation	SSKRVSRSLDGAPIG CCCHHHHCCCCCCCC	24.25	29255136
559	Sulfoxidation	DGAPIGVMDQSLMKD CCCCCCEECHHHHHC	3.06	21406390
562	Phosphorylation	PIGVMDQSLMKDFPG CCCEECHHHHHCCCC	26.60	30266825
575	Phosphorylation	PGAAGEISAYGPGLV CCCCCCCEEECCCEE	15.90	29978859
577	Phosphorylation	AAGEISAYGPGLVSI CCCCCEEECCCEEEE	19.64	27259358
583	Phosphorylation	AYGPGLVSIAVVQDG EECCCEEEEEEEECC	15.18	28442448
598	Phosphorylation	DGRREVRSPTKAPHL CCCEEECCCCCCCCE	41.94	22167270
598 (in isoform 4)	Phosphorylation	-	41.94	25849741
600	Phosphorylation	RREVRSPTKAPHLQL CEEECCCCCCCCEEE	40.88	30266825
600 (in isoform 4)	Phosphorylation	-	40.88	25849741
601	Ubiquitination	REVRSPTKAPHLQLI EEECCCCCCCCEEEE	64.40	-
611	Ubiquitination	HLQLIEGKKNSLRVE CEEEECCCCCCEEEE	35.67	-
612 (in isoform 2)	Phosphorylation	-	63.73	28842319
612 (in isoform 4)	Phosphorylation	-	63.73	25849741
613 (in isoform 4)	Phosphorylation	-	50.16	25849741
614	Phosphorylation	LIEGKKNSLRVEGDN EECCCCCCEEEECCE	26.82	23927012
616 (in isoform 4)	Phosphorylation	-	25.02	29116813
623	Phosphorylation	RVEGDNIYVRHSNLM EEECCEEEEECCHHH	9.55	27273156
627	Phosphorylation	DNIYVRHSNLMLEEL CEEEEECCHHHHHHH	22.54	26657352
643	Methylation	KAQEDILKHQASISE HHHHHHHHHHHHHHH	33.72	-
643	Ubiquitination	KAQEDILKHQASISE HHHHHHHHHHHHHHH	33.72	-
647	Phosphorylation	DILKHQASISELKRN HHHHHHHHHHHHHHH	21.78	23401153
649	Phosphorylation	LKHQASISELKRNFM HHHHHHHHHHHHHHH	34.09	29255136
652	Methylation	QASISELKRNFMEST HHHHHHHHHHHHHCC	41.04	-
652	Ubiquitination	QASISELKRNFMEST HHHHHHHHHHHHHCC	41.04	-
658	Phosphorylation	LKRNFMESTPEPRPN HHHHHHHCCCCCCCC	37.16	29255136
659	Phosphorylation	KRNFMESTPEPRPNE HHHHHHCCCCCCCCH	20.54	29255136
669	Acetylation	PRPNEWEKRRITPLS CCCCHHHHCCCCCCE	48.31	7925951
673	Phosphorylation	EWEKRRITPLSLQTQ HHHHCCCCCCEEECC	19.16	30266825
676	Phosphorylation	KRRITPLSLQTQGSS HCCCCCCEEECCCCC	21.45	30266825
679	Phosphorylation	ITPLSLQTQGSSHET CCCCEEECCCCCCCH	39.94	30266825
682	Phosphorylation	LSLQTQGSSHETLNI CEEECCCCCCCHHHH	20.78	30266825
683	Phosphorylation	SLQTQGSSHETLNIV EEECCCCCCCHHHHH	31.97	29255136
686	Phosphorylation	TQGSSHETLNIVEEK CCCCCCCHHHHHHHH	21.49	30266825
693	Ubiquitination	TLNIVEEKKRAEVGK HHHHHHHHHHHHCCC	33.77	21890473
694	Acetylation	LNIVEEKKRAEVGKD HHHHHHHHHHHCCCC	61.18	2520145
703 (in isoform 4)	Phosphorylation	-	34.96	27642862
706	Phosphorylation	GKDERVITEEMNGKE CCCCCEEEECCCCEE	24.04	24732914
712	Ubiquitination	ITEEMNGKEISPGSG EEECCCCEECCCCCC	47.04	21890473
715	Phosphorylation	EMNGKEISPGSGPGE CCCCEECCCCCCCCC	25.05	19664994
718	Phosphorylation	GKEISPGSGPGEIRK CEECCCCCCCCCEEE	45.24	19664994
734	Phosphorylation	EPVTQKDSTSLSSES EECCCCCCCCCCCCC	27.25	-
741	Phosphorylation	STSLSSESSSSSSES CCCCCCCCCCCCCCC	37.15	28348404
742	Phosphorylation	TSLSSESSSSSSESE CCCCCCCCCCCCCCC	30.13	28348404
743	Phosphorylation	SLSSESSSSSSESEE CCCCCCCCCCCCCCC	43.44	28348404
744	Phosphorylation	LSSESSSSSSESEEE CCCCCCCCCCCCCCC	39.57	28348404
745	Phosphorylation	SSESSSSSSESEEED CCCCCCCCCCCCCCC	39.82	28348404
746	Phosphorylation	SESSSSSSESEEEDV CCCCCCCCCCCCCCC	47.27	29523821
748	Phosphorylation	SSSSSSESEEEDVGE CCCCCCCCCCCCCCC	52.86	29523821
756	Phosphorylation	EEEDVGEYRPHHRVT CCCCCCCCCCCCCCC	24.42	-
763	Phosphorylation	YRPHHRVTEGTIREE CCCCCCCCCCCCCCH	28.75	26657352
766	Phosphorylation	HHRVTEGTIREEQEY CCCCCCCCCCCHHHH	15.61	28796482
768	Methylation	RVTEGTIREEQEYEE CCCCCCCCCHHHHHH	41.03	-
773	Phosphorylation	TIREEQEYEEEVEEE CCCCHHHHHHHHHCC	28.47	28674151
798	Phosphorylation	EEAVPEASPVTQAGA HHHCCCCCCCCCCCC	20.45	25159151
801	Phosphorylation	VPEASPVTQAGASVI CCCCCCCCCCCCEEE	18.98	28387310
806	Phosphorylation	PVTQAGASVITVETV CCCCCCCEEEEEEEE	17.09	26657352
809	Phosphorylation	QAGASVITVETVIQE CCCCEEEEEEEEEHH	15.33	24732914
812	Phosphorylation	ASVITVETVIQENVG CEEEEEEEEEHHCCC	20.69	29496963
827	Ubiquitination	AQKIPGEKSVHEGAL CCCCCCCCCCCCCCC	64.79	21890473
828	Phosphorylation	QKIPGEKSVHEGALK CCCCCCCCCCCCCCC	25.14	25755297
875	Phosphorylation	SEPPVVKTEMVTISD CCCCEEEEEEEEECC	20.08	-
877	Sulfoxidation	PPVVKTEMVTISDAS CCEEEEEEEEECCHH	3.79	21406390
879	Phosphorylation	VVKTEMVTISDASQR EEEEEEEEECCHHHC	17.29	29978859
881	Phosphorylation	KTEMVTISDASQRTE EEEEEEECCHHHCCC	20.12	29978859
884	Phosphorylation	MVTISDASQRTEIST EEEECCHHHCCCCCC	25.78	29978859
892	Ubiquitination	QRTEISTKEVPIVQT HCCCCCCCCCCEEEE	50.34	21890473
899	O-linked_Glycosylation	KEVPIVQTETKTITY CCCCEEEEEEEEEEE	34.43	23301498
903	Phosphorylation	IVQTETKTITYESPQ EEEEEEEEEEEECCC	26.43	29978859
905	Phosphorylation	QTETKTITYESPQID EEEEEEEEEECCCCC	26.85	28796482
906	Phosphorylation	TETKTITYESPQIDG EEEEEEEEECCCCCC	15.57	28796482
908	O-linked_Glycosylation	TKTITYESPQIDGGA EEEEEEECCCCCCCC	16.22	23301498
908	Phosphorylation	TKTITYESPQIDGGA EEEEEEECCCCCCCC	16.22	28796482
919	Phosphorylation	DGGAGGDSGTLLTAQ CCCCCCCCCEEEEEE	36.63	29978859
921	O-linked_Glycosylation	GAGGDSGTLLTAQTI CCCCCCCEEEEEEEE	23.65	23301498
921	Phosphorylation	GAGGDSGTLLTAQTI CCCCCCCEEEEEEEE	23.65	29978859
924	Phosphorylation	GDSGTLLTAQTITSE CCCCEEEEEEEEECC	21.60	29978859
927	O-linked_Glycosylation	GTLLTAQTITSESVS CEEEEEEEEECCCCC	24.61	23301498
927	Phosphorylation	GTLLTAQTITSESVS CEEEEEEEEECCCCC	24.61	29978859
929	Phosphorylation	LLTAQTITSESVSTT EEEEEEEECCCCCCE	29.81	29978859
930	O-linked_Glycosylation	LTAQTITSESVSTTT EEEEEEECCCCCCEE	24.83	23301498
930	Phosphorylation	LTAQTITSESVSTTT EEEEEEECCCCCCEE	24.83	29978859
944	Phosphorylation	TTTHITKTVKGGISE EEEEEEEECCCCCCC	20.85	-
946	Ubiquitination	THITKTVKGGISETR EEEEEECCCCCCCCE	57.56	-
950	Phosphorylation	KTVKGGISETRIEKR EECCCCCCCCEEEEE	35.87	23025827
952	Phosphorylation	VKGGISETRIEKRIV CCCCCCCCEEEEEEE	30.10	23186163
987	Phosphorylation	REQHPDMSVTRVVVH HHHCCCCCEEEEEEE	27.93	25159151
989	Phosphorylation	QHPDMSVTRVVVHKE HCCCCCEEEEEEECH	15.50	24719451
995	Ubiquitination	VTRVVVHKETELAEE EEEEEEECHHHHHHC	55.51	21890473
997	Phosphorylation	RVVVHKETELAEEGE EEEEECHHHHHHCCC	40.89	28857561

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of E41L2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of E41L2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of E41L2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
CALD1_HUMAN	CALD1	physical	22863883
CSN4_HUMAN	COPS4	physical	22863883
CSK21_HUMAN	CSNK2A1	physical	22863883
MEP50_HUMAN	WDR77	physical	22863883
E41L1_HUMAN	EPB41L1	physical	28514442
ENL_HUMAN	MLLT1	physical	28514442
AF9_HUMAN	MLLT3	physical	28514442
RNPS1_HUMAN	RNPS1	physical	28514442
PININ_HUMAN	PNN	physical	28514442
ACINU_HUMAN	ACIN1	physical	28514442
GPTC8_HUMAN	GPATCH8	physical	28514442
CWC22_HUMAN	CWC22	physical	28514442
E41L3_HUMAN	EPB41L3	physical	28514442
SET1A_HUMAN	SETD1A	physical	28514442
ZRAB2_HUMAN	ZRANB2	physical	28514442
ICLN_HUMAN	CLNS1A	physical	28514442
SRRM2_HUMAN	SRRM2	physical	28514442
CLK2_HUMAN	CLK2	physical	28514442
NKAP_HUMAN	NKAP	physical	28514442
SRP68_HUMAN	SRP68	physical	28514442
POTEI_HUMAN	POTEI	physical	28514442
AP3B1_HUMAN	AP3B1	physical	28514442
PPIG_HUMAN	PPIG	physical	28514442
1433G_HUMAN	YWHAG	physical	28514442
1433Z_HUMAN	YWHAZ	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of E41L2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-386 AND SER-550, ANDMASS SPECTROMETRY.	19690332 [Abstract]
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