SWT1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SWT1_HUMAN
• UniProt AC: Q5T5J6
• Protein Name: Transcriptional protein SWT1
• Gene Name: SWT1
• Organism: Homo sapiens (Human).
• Sequence Length: 900
• Protein Sequence: MSSKESCGKKETSQRKDTTTSSPNFGEKDKKERKTPASSTSSSSIRSVSSEKRKLKSDHTDVLYYNIKRRQGLKRLSVEIDTLRRRPKIGSSSQRPIKLKEASYSNDNQIILQSPSSNGTKKDIHKCVDFKPKDIKLTNAGSKLDHGIKSLSSPKIASDVKPKAEGQASENKWSHLLVQREKMKELKKGRNSKFRDNSEKCVLEKWKRNQFSQDYNSNKIIKEPLGSRRQKISFKIPIKSRDTLQKLVEENVFNIDSNNSKTKQEEREYLESSQVSLNVTRQKTEHLLSDFTYKRTVHEWKRKHHYDHQESNDSHSRENLTQSFEAPCCSVSSESIQDADQEMQIVEELHAARVGKSVDLPGELMSMEIDLEDDVHSSSANNTSDRKLLIVIDTNILMNHLKFVRILKTTEVPGFDKLVLIIPWVVMQELDRMKEGKLLKRAQHKAIPAVHFINDSLKNQDRKLWGQSIQLASQKHYGLSDENNDDRVLKCCLQHQELFPCSFVILCTDDRNLRNKGLISGVKSLSKEELSAELLHLSLNTDVCHQPCIPKQQLKAETTPLKESYKEESTNSGLSILLESIVSDLEKSLGTGLSSILETEMKIAFGNLWMEILYLKPPWTLLHLLQCFKKHWLAVFGLVMEKNLLLTIESLYKNLRKANKAVDFTTVKFLLQDSRSLLHAFSTRSNYDGILPQTFAQVNNLLQTFAEVKTKLKPNSSENTVTKKQEGTSLKNSHNQEITVFSSSHLPQPSRHQEIWSILESVWITIYQNSTDVFQRLGSNSALTTSNIASFEEAFICLQKLMAAVRDILEGIQRILAPNSNYQDVETLYNFLIKYEVNKNVKFTAQEIYDCVSQTEYREKLTIGCRQLVEMEYTMQQCNASVYMEAKNRGWCEDMLNYRI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSKESCGK ------CCCHHCCCC	50.55	27174698
3	Phosphorylation	-----MSSKESCGKK -----CCCHHCCCCC	38.86	27174698
6	O-linked_Glycosylation	--MSSKESCGKKETS --CCCHHCCCCCCCC	31.72	30379171
6	Phosphorylation	--MSSKESCGKKETS --CCCHHCCCCCCCC	31.72	27174698
10	Acetylation	SKESCGKKETSQRKD CHHCCCCCCCCCCCC	52.05	7220233
12	Phosphorylation	ESCGKKETSQRKDTT HCCCCCCCCCCCCCC	38.75	27174698
13	Phosphorylation	SCGKKETSQRKDTTT CCCCCCCCCCCCCCC	29.13	27174698
18	Phosphorylation	ETSQRKDTTTSSPNF CCCCCCCCCCCCCCC	34.70	-
20	Phosphorylation	SQRKDTTTSSPNFGE CCCCCCCCCCCCCCC	29.33	-
21	Phosphorylation	QRKDTTTSSPNFGEK CCCCCCCCCCCCCCC	41.53	25159151
22	Phosphorylation	RKDTTTSSPNFGEKD CCCCCCCCCCCCCCC	23.05	21815630
43	Phosphorylation	PASSTSSSSIRSVSS CCCCCCHHHHHHCCH	29.56	-
47	Phosphorylation	TSSSSIRSVSSEKRK CCHHHHHHCCHHCCC	25.36	-
49	Phosphorylation	SSSIRSVSSEKRKLK HHHHHHCCHHCCCCC	33.74	-
64	Phosphorylation	SDHTDVLYYNIKRRQ CCCCHHHHHHHHHHC	8.36	25627689
77	Phosphorylation	RQGLKRLSVEIDTLR HCCCCEEEEEHHHHH	23.03	27251275
91	Phosphorylation	RRRPKIGSSSQRPIK HCCCCCCCCCCCCEE	30.23	26074081
92	Phosphorylation	RRPKIGSSSQRPIKL CCCCCCCCCCCCEEE	25.85	26074081
93	Phosphorylation	RPKIGSSSQRPIKLK CCCCCCCCCCCEEEE	31.72	26074081
138	O-linked_Glycosylation	KPKDIKLTNAGSKLD CCCCCEECCCCCCCC	20.30	30379171
150	Phosphorylation	KLDHGIKSLSSPKIA CCCHHHHHCCCCCCC	31.40	23312004
152	Phosphorylation	DHGIKSLSSPKIASD CHHHHHCCCCCCCCC	52.24	23312004
158	Phosphorylation	LSSPKIASDVKPKAE CCCCCCCCCCCCCCC	46.54	-
169	Phosphorylation	PKAEGQASENKWSHL CCCCCCCCCCHHHHH	33.54	-
233	Phosphorylation	GSRRQKISFKIPIKS CCCCCEEEEECCCCC	27.76	24719451
257	Phosphorylation	ENVFNIDSNNSKTKQ HCCCCCCCCCCCCHH	33.83	24275569
293	Phosphorylation	HLLSDFTYKRTVHEW HHHCCCCCCCCHHHH	9.85	-
520	Phosphorylation	LRNKGLISGVKSLSK HHCCCCCHHHHCCCH	42.44	-
526	Phosphorylation	ISGVKSLSKEELSAE CHHHHCCCHHHHHHH	45.15	-
665	Phosphorylation	ANKAVDFTTVKFLLQ HHHCCCHHHHHHHHH	26.64	20873877
666	Phosphorylation	NKAVDFTTVKFLLQD HHCCCHHHHHHHHHC	22.99	20873877
711	Ubiquitination	TFAEVKTKLKPNSSE HHHHHHHHCCCCCCC	49.12	-
733	Phosphorylation	EGTSLKNSHNQEITV CCCCCCCCCCCEEEE	23.40	27732954
739	Phosphorylation	NSHNQEITVFSSSHL CCCCCEEEEEECCCC	18.10	27732954
742	Phosphorylation	NQEITVFSSSHLPQP CCEEEEEECCCCCCC	26.96	27732954
743	Phosphorylation	QEITVFSSSHLPQPS CEEEEEECCCCCCCC	15.43	27732954
744	Phosphorylation	EITVFSSSHLPQPSR EEEEEECCCCCCCCC	28.04	27732954
750	Phosphorylation	SSHLPQPSRHQEIWS CCCCCCCCCHHHHHH	36.83	27732954
842	Ubiquitination	YEVNKNVKFTAQEIY HHCCCCCCEEHHHHH	46.52	-
873	Phosphorylation	RQLVEMEYTMQQCNA HHHHHHHHHHHHCCC	13.25	-
874	Phosphorylation	QLVEMEYTMQQCNAS HHHHHHHHHHHCCCC	8.66	-
881	Phosphorylation	TMQQCNASVYMEAKN HHHHCCCCCEEECCC	10.37	-
883	Phosphorylation	QQCNASVYMEAKNRG HHCCCCCEEECCCCC	6.17	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SWT1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SWT1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SWT1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of SWT1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.