SRTD4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SRTD4_HUMAN
• UniProt AC: Q9NUC0
• Protein Name: SERTA domain-containing protein 4
• Gene Name: SERTAD4
• Organism: Homo sapiens (Human).
• Sequence Length: 356
• Protein Sequence: MTLVLSMNRFCEPIVSEGAAEIAGYQTLWEADSYGGPSPPGPAQAPLQGDRGAGPPLAGSHYRGISNPITTSKITYFKRKYVEEEDFHPPLSSCSHKTISIFEERAHILYMSLEKLKFIDDPEVYLRRSVLINNLMKRIHGEIIMQNNWCFPACSFNGTSAQEWFMAQDCPYRKRPRMAKEECEKFHACCFYQECGGHYLNLPLSVNANVGSASTAASSPSASSSSSSSSSSPPLPLPSCSRQVDFDVGSASIYKSDGQIPANEIFVTNVRSLGVQEKAKLNDEKANDDTNRDGGPLSHEPVGNDLAFECKGQFYDYFETGYNERNNVNESWKKSLRKKEASPPSNKLCCSKGSKI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MTLVLSMNRFCEP --CEEEEECCCCCCC	13.41	22985185
51	Methylation	QAPLQGDRGAGPPLA CCCCCCCCCCCCCCC	43.62	54559143
60	Phosphorylation	AGPPLAGSHYRGISN CCCCCCCCCCCCCCC	16.25	30631047
225	Phosphorylation	SSPSASSSSSSSSSS CCCCCCCCCCCCCCC	31.57	-
226	Phosphorylation	SPSASSSSSSSSSSP CCCCCCCCCCCCCCC	35.87	-
227	Phosphorylation	PSASSSSSSSSSSPP CCCCCCCCCCCCCCC	35.87	-
228	Phosphorylation	SASSSSSSSSSSPPL CCCCCCCCCCCCCCC	35.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SRTD4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SRTD4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SRTD4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
POTEF_HUMAN	POTEF	physical	26186194
ZFP1_HUMAN	ZFP1	physical	26186194
2AAB_HUMAN	PPP2R1B	physical	26186194
2AAA_HUMAN	PPP2R1A	physical	26186194
2ABD_HUMAN	PPP2R2D	physical	26186194
2ABA_HUMAN	PPP2R2A	physical	26186194
PP2AA_HUMAN	PPP2CA	physical	26186194
PP2AB_HUMAN	PPP2CB	physical	26186194
2ABD_HUMAN	PPP2R2D	physical	28514442
ZFP1_HUMAN	ZFP1	physical	28514442
PP2AA_HUMAN	PPP2CA	physical	28514442
2AAB_HUMAN	PPP2R1B	physical	28514442
2ABA_HUMAN	PPP2R2A	physical	28514442
POTEF_HUMAN	POTEF	physical	28514442
2AAA_HUMAN	PPP2R1A	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.