| UniProt ID | GP149_HUMAN | |
|---|---|---|
| UniProt AC | Q86SP6 | |
| Protein Name | Probable G-protein coupled receptor 149 | |
| Gene Name | GPR149 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 731 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein. |
|
| Protein Description | Orphan receptor.. | |
| Protein Sequence | MSLFLSNLSTNDSSLWKENHNSTDLLNPPGTLNIYLFCLTCLMTFAALVGSIYSLISLLKMQNRTVVSMLVASWSVDDLMSVLSVTIFMFLQWPNEVPGYFQFLCTTSALMYLCQGLSSNLKATLLVSYNFYTMHRGVGSQTASRRSGQVLGVVLTVWAASLLLSALPLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCSEEPPRLHSNYQEISRGASIPGTPPTAGRVVSLSPEDAPGPSLRRSGGCSPSSDTVFGPGAPAAAGAEACRRENRGTLYGTRSFTVSVAQKRFALILALTKVVLWLPMMMHMVVQNVVGFQSLPLETFSFLLTLLATTVTPVFVLSKRWTHLPCGCIINCRQNAYAVASDGKKIKRKGFEFNLSFQKSYGIYKIAHEDYYDDDENSIFYHNLMNSECETTKDPQRDNRNIFNAIKVEISTTPSLDSSTQRGINKCTNTDITEAKQDSNNKKDAFSDKTGGDINYEETTFSEGPERRLSHEESQKPDLSDWEWCRSKSERTPRQRSGYALAIPLCAFQGTVSLHAPTGKTLSLSTYEVSAEGQKITPASKKIEVYRSKSVGHEPNSEDSSSTFVDTSVKIHLEVLEICDNEEALDTVSIISNISQSSTQVRSPSLRYSRKENRFVSCDLGETASYSLFLPTSNPDGDINISIPDTVEAHRQNSKRQHQERDGYQEEIQLLNKAYRKREEESKGS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
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||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | N-linked_Glycosylation | -MSLFLSNLSTNDSS -CCCCCCCCCCCCHH | 39.91 | UniProtKB CARBOHYD | |
| 11 | N-linked_Glycosylation | FLSNLSTNDSSLWKE CCCCCCCCCHHHHHC | 43.73 | UniProtKB CARBOHYD | |
| 21 | N-linked_Glycosylation | SLWKENHNSTDLLNP HHHHCCCCCCCCCCC | 59.18 | UniProtKB CARBOHYD | |
| 57 | Phosphorylation | GSIYSLISLLKMQNR HHHHHHHHHHHHCCH | 32.70 | 24719451 | |
| 124 | Phosphorylation | LSSNLKATLLVSYNF HCCCCCEEEEEEEEE | 21.02 | 27732954 | |
| 140 | Phosphorylation | TMHRGVGSQTASRRS ECCCCCCCCCCHHHH | 23.19 | 25072903 | |
| 142 | Phosphorylation | HRGVGSQTASRRSGQ CCCCCCCCCHHHHCC | 28.44 | 25072903 | |
| 144 | Phosphorylation | GVGSQTASRRSGQVL CCCCCCCHHHHCCHH | 31.45 | 25072903 | |
| 250 | Phosphorylation | PTAGRVVSLSPEDAP CCCCCEEEECCCCCC | 21.92 | - | |
| 252 | Phosphorylation | AGRVVSLSPEDAPGP CCCEEEECCCCCCCC | 20.81 | - | |
| 295 | Phosphorylation | CRRENRGTLYGTRSF HHHHCCCCCCCCCCE | 17.36 | - | |
| 303 | Phosphorylation | LYGTRSFTVSVAQKR CCCCCCEEEEHHHHH | 17.08 | - | |
| 318 | Phosphorylation | FALILALTKVVLWLP HHHHHHHHHHHHHHH | 19.04 | - | |
| 459 | Phosphorylation | IKVEISTTPSLDSST EEEEEECCCCCCCCC | 12.23 | - | |
| 535 | Phosphorylation | WEWCRSKSERTPRQR HHHHHCCCCCCCCCC | 33.29 | 22798277 | |
| 538 | Phosphorylation | CRSKSERTPRQRSGY HHCCCCCCCCCCCCE | 20.83 | 22798277 | |
| 543 | Phosphorylation | ERTPRQRSGYALAIP CCCCCCCCCEEEHHC | 28.02 | - | |
| 559 | Phosphorylation | CAFQGTVSLHAPTGK HHHCCEEEEECCCCC | 17.80 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GP149_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GP149_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GP149_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GP149_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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