| UniProt ID | DPPA4_HUMAN | |
|---|---|---|
| UniProt AC | Q7L190 | |
| Protein Name | Developmental pluripotency-associated protein 4 | |
| Gene Name | DPPA4 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 304 | |
| Subcellular Localization | Nucleus . Associated with transcriptionally active chromatin. | |
| Protein Description | May be involved in the maintenance of active epigenetic status of target genes. May inhibit differentiation of embryonic cells into a primitive ectoderm lineage.. | |
| Protein Sequence | MLRGSASSTSMEKAKGKEWTSTEKSREEDQQASNQPNSIALPGTSAKRTKEKMSIKGSKVLCPKKKAEHTDNPRPQKKIPIPPLPSKLPPVNLIHRDILRAWCQQLKLSSKGQKLDAYKRLCAFAYPNQKDFPSTAKEAKIRKSLQKKLKVEKGETSLQSSETHPPEVALPPVGEPPALENSTALLEGVNTVVVTTSAPEALLASWARISARARTPEAVESPQEASGVRWCVVHGKSLPADTDGWVHLQFHAGQAWVPEKQEGRVSALFLLPASNFPPPHLEDNMLCPKCVHRNKVLIKSLQWE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MLRGSASSTSME ---CCCCCCCCCHHH | 20.67 | 21406692 | |
| 7 | Phosphorylation | -MLRGSASSTSMEKA -CCCCCCCCCHHHHH | 35.53 | 21406692 | |
| 8 | Phosphorylation | MLRGSASSTSMEKAK CCCCCCCCCHHHHHC | 24.98 | 21406692 | |
| 9 | Phosphorylation | LRGSASSTSMEKAKG CCCCCCCCHHHHHCC | 29.60 | 21406692 | |
| 10 | Phosphorylation | RGSASSTSMEKAKGK CCCCCCCHHHHHCCC | 27.22 | 21406692 | |
| 25 | Phosphorylation | EWTSTEKSREEDQQA CCCCCHHHHHHHHHH | 38.40 | - | |
| 47 | Ubiquitination | ALPGTSAKRTKEKMS ECCCCCCCCCCCCCC | 61.44 | - | |
| 54 | Phosphorylation | KRTKEKMSIKGSKVL CCCCCCCCCCCCEEE | 32.01 | 16674116 | |
| 86 | Phosphorylation | IPIPPLPSKLPPVNL CCCCCCCCCCCCCCC | 55.28 | 24719451 | |
| 87 | Ubiquitination | PIPPLPSKLPPVNLI CCCCCCCCCCCCCCC | 64.17 | - | |
| 215 | Phosphorylation | RISARARTPEAVESP HHHHHCCCHHHHCCC | 25.21 | 19664994 | |
| 221 | Phosphorylation | RTPEAVESPQEASGV CCHHHHCCCHHHCCC | 25.86 | 19664995 | |
| 226 | Phosphorylation | VESPQEASGVRWCVV HCCCHHHCCCCEEEE | 36.75 | 14702039 | |
| 299 | Ubiquitination | HRNKVLIKSLQWE-- HCCCEEEEECCCC-- | 40.74 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DPPA4_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DPPA4_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DPPA4_HUMAN !! | ||||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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