CI131_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CI131_HUMAN
• UniProt AC: Q5VYM1
• Protein Name: Uncharacterized protein C9orf131
• Gene Name: C9orf131
• Organism: Homo sapiens (Human).
• Sequence Length: 1079
• Protein Sequence: MEWLLEDLLGAKGDMGLLWGQLTHALACRHCGSSCFQSPGNLVTLFLFVVWQIQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
77	Ubiquitination	SGNMVQGKELPLLHR CCCCCCCCCCCHHHH	38.70	-
162	Phosphorylation	QTVMQPVSPSRSFPI CCEECCCCCCCCCCH	24.68	29083192
164	Phosphorylation	VMQPVSPSRSFPIFQ EECCCCCCCCCCHHH	32.81	29083192
218	Phosphorylation	FLSSGGPSPLKWSVC HHCCCCCCCCCHHHH	46.25	27794612
402	Phosphorylation	LPELQRESSLEDPSR CHHHHHHCCCCCHHH	42.27	26552605
403	Phosphorylation	PELQRESSLEDPSRY HHHHHHCCCCCHHHC	30.90	26552605
408	Phosphorylation	ESSLEDPSRYKPQWE HCCCCCHHHCCCCCE	61.64	26552605
410	Phosphorylation	SLEDPSRYKPQWECR CCCCHHHCCCCCEEE	31.21	26552605
943	Acetylation	ASASSSAKKREHPRK CCCCCCHHHCCCCCC	55.07	24848059
950	Acetylation	KKREHPRKPKAGDHR HHCCCCCCCCCCCCC	56.15	7960511
960	Phosphorylation	AGDHRRGTARLGLST CCCCCCCCCCCCCEE	13.54	-
969	Phosphorylation	RLGLSTVTGKNHPAQ CCCCEECCCCCCHHH	42.39	-
998	Phosphorylation	RSQHRGQSSQHTALP CCCCCCCCCCCCCHH	34.49	29083192
999	Phosphorylation	SQHRGQSSQHTALPQ CCCCCCCCCCCCHHH	20.35	29083192
1002	Phosphorylation	RGQSSQHTALPQLLL CCCCCCCCCHHHHHC	23.42	18491316
1013	Phosphorylation	QLLLPKASGPQDQPE HHHCCCCCCCCCCCH	58.07	22468782
1026	Phosphorylation	PEAGRRASDILTPRH CHHHCCHHHCCCHHH	24.31	22468782
1050	Phosphorylation	EKYLSFPTLKASLTR HHHHHHHHHHHHHHH	38.59	18491316
1061	Ubiquitination	SLTRGLQKVLAKCLD HHHHHHHHHHHHHHH	44.23	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CI131_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CI131_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CI131_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CI131_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.