| UniProt ID | CYTSB_HUMAN | |
|---|---|---|
| UniProt AC | Q5M775 | |
| Protein Name | Cytospin-B | |
| Gene Name | SPECC1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1068 | |
| Subcellular Localization |
Nucleus . Isoform 3: Membrane Lipid-anchor . Isoform 4: Membrane Lipid-anchor . Isoform 5: Membrane Lipid-anchor . |
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| Protein Description | ||
| Protein Sequence | MRSAAKPWNPAIRAGGHGPDRVRPLPAASSGMKSSKSSTSLAFESRLSRLKRASSEDTLNKPGSTAASGVVRLKKTATAGAISELTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTPSTKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAGRWPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQNISVHKTPRSPLSGIPVRTAPAAAVSPMQRHSTYSSVRPASRGVTQRLDLPDLPLSDILKGRTETLKPDPHLRKSPSLESLSRPPSLGFGDTRLLSASTRAWKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLYTDRPDWQSVMQYVAQIYKYFET | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 (in isoform 3) | Myristoylation | - | 46.43 | 25807930 | |
| 2 (in isoform 4) | Myristoylation | - | 46.43 | 25807930 | |
| 2 (in isoform 5) | Myristoylation | - | 46.43 | 25807930 | |
| 5 (in isoform 3) | Phosphorylation | - | 21.49 | 23322592 | |
| 5 (in isoform 4) | Phosphorylation | - | 21.49 | 23322592 | |
| 5 (in isoform 5) | Phosphorylation | - | 21.49 | 23322592 | |
| 34 | Phosphorylation | AASSGMKSSKSSTSL CCCCCCCCCCCHHHH | 33.82 | 28450419 | |
| 35 | Phosphorylation | ASSGMKSSKSSTSLA CCCCCCCCCCHHHHH | 30.91 | 28450419 | |
| 37 | Phosphorylation | SGMKSSKSSTSLAFE CCCCCCCCHHHHHHH | 40.57 | 26657352 | |
| 38 | Phosphorylation | GMKSSKSSTSLAFES CCCCCCCHHHHHHHH | 26.25 | 28450419 | |
| 39 | Phosphorylation | MKSSKSSTSLAFESR CCCCCCHHHHHHHHH | 34.55 | 28450419 | |
| 40 | Phosphorylation | KSSKSSTSLAFESRL CCCCCHHHHHHHHHH | 21.46 | 28450419 | |
| 45 | Phosphorylation | STSLAFESRLSRLKR HHHHHHHHHHHHHHH | 31.87 | 27251275 | |
| 48 | Phosphorylation | LAFESRLSRLKRASS HHHHHHHHHHHHCCC | 34.16 | 27251275 | |
| 50 (in isoform 3) | Phosphorylation | - | 3.85 | - | |
| 50 (in isoform 4) | Phosphorylation | - | 3.85 | - | |
| 52 (in isoform 3) | Phosphorylation | - | 44.27 | - | |
| 52 (in isoform 4) | Phosphorylation | - | 44.27 | - | |
| 53 (in isoform 3) | Phosphorylation | - | 18.80 | - | |
| 53 (in isoform 4) | Phosphorylation | - | 18.80 | - | |
| 54 | Phosphorylation | LSRLKRASSEDTLNK HHHHHHCCCCCCCCC | 37.99 | 25159151 | |
| 55 | Phosphorylation | SRLKRASSEDTLNKP HHHHHCCCCCCCCCC | 38.21 | 23401153 | |
| 55 (in isoform 3) | Phosphorylation | - | 38.21 | - | |
| 55 (in isoform 4) | Phosphorylation | - | 38.21 | - | |
| 56 (in isoform 3) | Phosphorylation | - | 53.14 | - | |
| 56 (in isoform 4) | Phosphorylation | - | 53.14 | - | |
| 57 (in isoform 3) | Phosphorylation | - | 59.44 | - | |
| 57 (in isoform 4) | Phosphorylation | - | 59.44 | - | |
| 58 | Phosphorylation | KRASSEDTLNKPGST HHCCCCCCCCCCCCC | 28.33 | 22115753 | |
| 59 (in isoform 3) | Phosphorylation | - | 13.84 | - | |
| 59 (in isoform 4) | Phosphorylation | - | 13.84 | - | |
| 61 (in isoform 3) | Phosphorylation | - | 54.60 | - | |
| 61 (in isoform 4) | Phosphorylation | - | 54.60 | - | |
| 64 | Phosphorylation | DTLNKPGSTAASGVV CCCCCCCCCCCCCEE | 24.33 | 28450419 | |
| 65 | Phosphorylation | TLNKPGSTAASGVVR CCCCCCCCCCCCEEE | 31.96 | 28060719 | |
| 68 | Phosphorylation | KPGSTAASGVVRLKK CCCCCCCCCEEEEEE | 29.65 | 28060719 | |
| 68 (in isoform 3) | Phosphorylation | - | 29.65 | - | |
| 68 (in isoform 4) | Phosphorylation | - | 29.65 | - | |
| 76 | Phosphorylation | GVVRLKKTATAGAIS CEEEEEECCCCCHHH | 27.87 | 28450419 | |
| 78 | Phosphorylation | VRLKKTATAGAISEL EEEEECCCCCHHHHH | 30.75 | 28450419 | |
| 83 | Phosphorylation | TATAGAISELTESRL CCCCCHHHHHHHHHH | 26.48 | 23186163 | |
| 88 | Phosphorylation | AISELTESRLRSGTG HHHHHHHHHHHCCCC | 31.23 | - | |
| 108 (in isoform 3) | Phosphorylation | - | 30.86 | - | |
| 108 (in isoform 4) | Phosphorylation | - | 30.86 | - | |
| 112 | Phosphorylation | IPAPREFSVTVSRER CCCCCEEEEEEECCC | 16.48 | 28355574 | |
| 114 | Phosphorylation | APREFSVTVSRERSV CCCEEEEEEECCCCC | 16.15 | 23312004 | |
| 116 | Phosphorylation | REFSVTVSRERSVPR CEEEEEEECCCCCCC | 21.04 | 21815630 | |
| 120 | Phosphorylation | VTVSRERSVPRGPSN EEEECCCCCCCCCCC | 31.55 | 27422710 | |
| 130 | Ubiquitination | RGPSNPRKSVSSPTS CCCCCCCCCCCCCCC | 57.37 | - | |
| 131 | Phosphorylation | GPSNPRKSVSSPTSS CCCCCCCCCCCCCCC | 28.63 | 22167270 | |
| 131 (in isoform 2) | Phosphorylation | - | 28.63 | - | |
| 133 | Phosphorylation | SNPRKSVSSPTSSNT CCCCCCCCCCCCCCC | 37.38 | 22167270 | |
| 133 (in isoform 2) | Phosphorylation | - | 37.38 | - | |
| 134 | Phosphorylation | NPRKSVSSPTSSNTP CCCCCCCCCCCCCCC | 30.00 | 30278072 | |
| 134 (in isoform 2) | Phosphorylation | - | 30.00 | - | |
| 136 | Phosphorylation | RKSVSSPTSSNTPTP CCCCCCCCCCCCCCC | 46.89 | 30278072 | |
| 136 (in isoform 2) | Phosphorylation | - | 46.89 | - | |
| 137 | Phosphorylation | KSVSSPTSSNTPTPT CCCCCCCCCCCCCCC | 25.60 | 25159151 | |
| 137 (in isoform 2) | Phosphorylation | - | 25.60 | - | |
| 137 (in isoform 3) | Phosphorylation | - | 25.60 | - | |
| 137 (in isoform 4) | Phosphorylation | - | 25.60 | - | |
| 138 | Phosphorylation | SVSSPTSSNTPTPTK CCCCCCCCCCCCCCC | 47.39 | 23927012 | |
| 138 (in isoform 2) | Phosphorylation | - | 47.39 | - | |
| 140 | Phosphorylation | SSPTSSNTPTPTKHL CCCCCCCCCCCCCCC | 30.41 | 23927012 | |
| 140 (in isoform 2) | Phosphorylation | - | 30.41 | - | |
| 142 | Phosphorylation | PTSSNTPTPTKHLRT CCCCCCCCCCCCCCC | 41.36 | 23927012 | |
| 142 (in isoform 2) | Phosphorylation | - | 41.36 | - | |
| 144 | Phosphorylation | SSNTPTPTKHLRTPS CCCCCCCCCCCCCCC | 33.31 | 23927012 | |
| 145 | Ubiquitination | SNTPTPTKHLRTPST CCCCCCCCCCCCCCC | 41.67 | - | |
| 149 | Phosphorylation | TPTKHLRTPSTKPKQ CCCCCCCCCCCCCCC | 28.13 | 20068231 | |
| 149 (in isoform 2) | Phosphorylation | - | 28.13 | - | |
| 151 | Phosphorylation | TKHLRTPSTKPKQEN CCCCCCCCCCCCCCC | 48.74 | 20068231 | |
| 152 | Phosphorylation | KHLRTPSTKPKQENE CCCCCCCCCCCCCCC | 53.20 | 20068231 | |
| 160 (in isoform 3) | Phosphorylation | - | 62.23 | - | |
| 160 (in isoform 4) | Phosphorylation | - | 62.23 | - | |
| 163 | Ubiquitination | QENEGGEKAALESQV CCCCHHHHHHHHHHH | 42.08 | - | |
| 168 | Phosphorylation | GEKAALESQVRELLA HHHHHHHHHHHHHHH | 34.52 | 25159151 | |
| 178 | Ubiquitination | RELLAEAKAKDSEIN HHHHHHHHHHHHHHH | 47.69 | - | |
| 189 | Phosphorylation | SEINRLRSELKKYKE HHHHHHHHHHHHHHH | 52.45 | 20068231 | |
| 189 (in isoform 2) | Phosphorylation | - | 52.45 | - | |
| 194 | Phosphorylation | LRSELKKYKEKRTLN HHHHHHHHHHHHCCC | 23.85 | 22468782 | |
| 199 | Phosphorylation | KKYKEKRTLNAEGTD HHHHHHHCCCCCCCC | 35.12 | 24732914 | |
| 205 | Phosphorylation | RTLNAEGTDALGPNV HCCCCCCCCCCCCCC | 15.03 | 24732914 | |
| 215 | Phosphorylation | LGPNVDGTSVSPGDT CCCCCCCCCCCCCCC | 22.84 | 21712546 | |
| 216 | Phosphorylation | GPNVDGTSVSPGDTE CCCCCCCCCCCCCCH | 26.57 | 25159151 | |
| 218 | Phosphorylation | NVDGTSVSPGDTEPM CCCCCCCCCCCCHHH | 23.96 | 25159151 | |
| 218 (in isoform 2) | Phosphorylation | - | 23.96 | - | |
| 222 | Phosphorylation | TSVSPGDTEPMIRAL CCCCCCCCHHHHHHH | 48.15 | 21712546 | |
| 230 (in isoform 3) | Phosphorylation | - | 66.97 | - | |
| 230 (in isoform 4) | Phosphorylation | - | 66.97 | - | |
| 231 (in isoform 3) | Phosphorylation | - | 63.88 | - | |
| 231 (in isoform 4) | Phosphorylation | - | 63.88 | - | |
| 233 (in isoform 3) | Phosphorylation | - | 48.02 | - | |
| 233 (in isoform 4) | Phosphorylation | - | 48.02 | - | |
| 234 (in isoform 3) | Phosphorylation | - | 70.93 | - | |
| 234 (in isoform 4) | Phosphorylation | - | 70.93 | - | |
| 235 (in isoform 3) | Phosphorylation | - | 54.71 | - | |
| 235 (in isoform 4) | Phosphorylation | - | 54.71 | - | |
| 236 (in isoform 3) | Phosphorylation | - | 13.50 | - | |
| 236 (in isoform 4) | Phosphorylation | - | 13.50 | - | |
| 238 | Acetylation | EKNKNFQKELSDLEE HHCHHHHHHHHHHHH | 57.39 | 26051181 | |
| 238 | Ubiquitination | EKNKNFQKELSDLEE HHCHHHHHHHHHHHH | 57.39 | - | |
| 239 (in isoform 3) | Phosphorylation | - | 42.60 | - | |
| 239 (in isoform 4) | Phosphorylation | - | 42.60 | - | |
| 241 | Phosphorylation | KNFQKELSDLEEENR HHHHHHHHHHHHHHH | 41.04 | 30266825 | |
| 241 (in isoform 2) | Phosphorylation | - | 41.04 | - | |
| 248 (in isoform 3) | Phosphorylation | - | 38.12 | - | |
| 248 (in isoform 4) | Phosphorylation | - | 38.12 | - | |
| 254 (in isoform 3) | Phosphorylation | - | 3.06 | - | |
| 254 (in isoform 4) | Phosphorylation | - | 3.06 | - | |
| 256 | Phosphorylation | VLKEKLIYLEHSPNS HHHHHEEEEECCCCC | 19.24 | 30576142 | |
| 257 (in isoform 3) | Phosphorylation | - | 3.65 | - | |
| 257 (in isoform 4) | Phosphorylation | - | 3.65 | - | |
| 259 (in isoform 3) | Phosphorylation | - | 46.06 | - | |
| 259 (in isoform 4) | Phosphorylation | - | 46.06 | - | |
| 260 | Phosphorylation | KLIYLEHSPNSEGAA HEEEEECCCCCCCCC | 19.19 | 30576142 | |
| 263 | Phosphorylation | YLEHSPNSEGAASHT EEECCCCCCCCCCCC | 40.57 | 20068231 | |
| 263 (in isoform 3) | Phosphorylation | - | 40.57 | - | |
| 263 (in isoform 4) | Phosphorylation | - | 40.57 | - | |
| 268 | Phosphorylation | PNSEGAASHTGDSSC CCCCCCCCCCCCCCC | 22.50 | 30576142 | |
| 275 (in isoform 3) | Phosphorylation | - | 5.02 | - | |
| 275 (in isoform 4) | Phosphorylation | - | 5.02 | - | |
| 276 (in isoform 3) | Phosphorylation | - | 31.00 | - | |
| 276 (in isoform 4) | Phosphorylation | - | 31.00 | - | |
| 277 | Phosphorylation | TGDSSCPTSITQESS CCCCCCCCCCCCCCC | 36.77 | 28348404 | |
| 278 | Phosphorylation | GDSSCPTSITQESSF CCCCCCCCCCCCCCC | 14.58 | 28348404 | |
| 279 (in isoform 3) | Phosphorylation | - | 5.19 | - | |
| 279 (in isoform 4) | Phosphorylation | - | 5.19 | - | |
| 280 | Phosphorylation | SSCPTSITQESSFGS CCCCCCCCCCCCCCC | 26.50 | 28348404 | |
| 280 (in isoform 3) | Phosphorylation | - | 26.50 | - | |
| 280 (in isoform 4) | Phosphorylation | - | 26.50 | - | |
| 283 | Phosphorylation | PTSITQESSFGSPTG CCCCCCCCCCCCCCC | 22.58 | 30576142 | |
| 283 (in isoform 3) | Phosphorylation | - | 22.58 | - | |
| 283 (in isoform 4) | Phosphorylation | - | 22.58 | - | |
| 284 | Phosphorylation | TSITQESSFGSPTGN CCCCCCCCCCCCCCC | 32.64 | 28348404 | |
| 285 (in isoform 3) | Phosphorylation | - | 18.29 | - | |
| 285 (in isoform 4) | Phosphorylation | - | 18.29 | - | |
| 287 | Phosphorylation | TQESSFGSPTGNQMS CCCCCCCCCCCCCCC | 19.78 | 28348404 | |
| 294 | Phosphorylation | SPTGNQMSSDIDEYK CCCCCCCCCCHHHHH | 18.33 | 30576142 | |
| 302 | Ubiquitination | SDIDEYKKNIHGNAL CCHHHHHHHHCCCCC | 61.30 | - | |
| 311 | Phosphorylation | IHGNALRTSGSSSSD HCCCCCCCCCCCHHH | 37.99 | 25159151 | |
| 311 (in isoform 2) | Phosphorylation | - | 37.99 | - | |
| 312 | Phosphorylation | HGNALRTSGSSSSDV CCCCCCCCCCCHHHC | 30.18 | 25159151 | |
| 312 (in isoform 2) | Phosphorylation | - | 30.18 | - | |
| 314 | Phosphorylation | NALRTSGSSSSDVTK CCCCCCCCCHHHCCH | 27.15 | 25159151 | |
| 314 (in isoform 2) | Phosphorylation | - | 27.15 | - | |
| 315 | Phosphorylation | ALRTSGSSSSDVTKA CCCCCCCCHHHCCHH | 37.07 | 25159151 | |
| 315 (in isoform 2) | Phosphorylation | - | 37.07 | - | |
| 316 | Phosphorylation | LRTSGSSSSDVTKAS CCCCCCCHHHCCHHH | 32.05 | 25159151 | |
| 316 (in isoform 2) | Phosphorylation | - | 32.05 | - | |
| 317 | Phosphorylation | RTSGSSSSDVTKASL CCCCCCHHHCCHHHC | 37.74 | 25159151 | |
| 317 (in isoform 2) | Phosphorylation | - | 37.74 | - | |
| 320 | Phosphorylation | GSSSSDVTKASLSPD CCCHHHCCHHHCCCC | 26.36 | 20068231 | |
| 320 (in isoform 2) | Phosphorylation | - | 26.36 | - | |
| 323 | Phosphorylation | SSDVTKASLSPDASD HHHCCHHHCCCCHHH | 30.82 | 22167270 | |
| 325 | Phosphorylation | DVTKASLSPDASDFE HCCHHHCCCCHHHHC | 20.45 | 23401153 | |
| 329 | Phosphorylation | ASLSPDASDFEHITA HHCCCCHHHHCCCCC | 50.65 | 22167270 | |
| 329 (in isoform 2) | Phosphorylation | - | 50.65 | - | |
| 335 | Phosphorylation | ASDFEHITAETPSRP HHHHCCCCCCCCCCC | 21.98 | 22167270 | |
| 335 (in isoform 2) | Phosphorylation | - | 21.98 | - | |
| 338 | Phosphorylation | FEHITAETPSRPLSS HCCCCCCCCCCCCCC | 24.89 | 22167270 | |
| 338 (in isoform 2) | Phosphorylation | - | 24.89 | - | |
| 340 | Phosphorylation | HITAETPSRPLSSTS CCCCCCCCCCCCCCC | 54.68 | 22167270 | |
| 340 (in isoform 2) | Phosphorylation | - | 54.68 | - | |
| 344 | Phosphorylation | ETPSRPLSSTSNPFK CCCCCCCCCCCCCCC | 33.96 | 22167270 | |
| 344 (in isoform 2) | Phosphorylation | - | 33.96 | - | |
| 344 (in isoform 3) | Phosphorylation | - | 33.96 | - | |
| 344 (in isoform 4) | Phosphorylation | - | 33.96 | - | |
| 345 | Phosphorylation | TPSRPLSSTSNPFKS CCCCCCCCCCCCCCC | 43.46 | 22167270 | |
| 346 | Phosphorylation | PSRPLSSTSNPFKSS CCCCCCCCCCCCCCC | 29.19 | 22167270 | |
| 347 | Phosphorylation | SRPLSSTSNPFKSSK CCCCCCCCCCCCCCC | 44.44 | 22167270 | |
| 351 | Ubiquitination | SSTSNPFKSSKCSTA CCCCCCCCCCCCCCC | 55.89 | - | |
| 352 | Phosphorylation | STSNPFKSSKCSTAG CCCCCCCCCCCCCCC | 35.09 | 23312004 | |
| 353 | Phosphorylation | TSNPFKSSKCSTAGS CCCCCCCCCCCCCCC | 37.97 | 23312004 | |
| 356 | Phosphorylation | PFKSSKCSTAGSSPN CCCCCCCCCCCCCCC | 25.65 | 22167270 | |
| 356 (in isoform 2) | Phosphorylation | - | 25.65 | - | |
| 357 | Phosphorylation | FKSSKCSTAGSSPNS CCCCCCCCCCCCCCC | 44.50 | 22167270 | |
| 357 (in isoform 2) | Phosphorylation | - | 44.50 | - | |
| 360 | Phosphorylation | SKCSTAGSSPNSVSE CCCCCCCCCCCCHHH | 39.91 | 22167270 | |
| 360 (in isoform 2) | Phosphorylation | - | 39.91 | - | |
| 361 | Phosphorylation | KCSTAGSSPNSVSEL CCCCCCCCCCCHHHH | 27.47 | 22167270 | |
| 361 (in isoform 2) | Phosphorylation | - | 27.47 | - | |
| 364 | Phosphorylation | TAGSSPNSVSELSLA CCCCCCCCHHHHHHH | 30.33 | 22167270 | |
| 364 (in isoform 2) | Phosphorylation | - | 30.33 | - | |
| 366 | Phosphorylation | GSSPNSVSELSLASL CCCCCCHHHHHHHHH | 32.42 | 22167270 | |
| 366 (in isoform 2) | Phosphorylation | - | 32.42 | - | |
| 369 | Phosphorylation | PNSVSELSLASLTEK CCCHHHHHHHHHHHH | 20.17 | 24732914 | |
| 372 | Phosphorylation | VSELSLASLTEKIQK HHHHHHHHHHHHHHH | 40.91 | 24732914 | |
| 374 | Phosphorylation | ELSLASLTEKIQKME HHHHHHHHHHHHHHH | 32.51 | 24732914 | |
| 376 | Ubiquitination | SLASLTEKIQKMEEN HHHHHHHHHHHHHHC | 45.24 | - | |
| 414 | Ubiquitination | ELTAENEKLVDEKTI HHHHHHHHHCCHHHH | 66.45 | - | |
| 419 | 2-Hydroxyisobutyrylation | NEKLVDEKTILETSF HHHHCCHHHHHHHHH | 36.08 | - | |
| 419 | Ubiquitination | NEKLVDEKTILETSF HHHHCCHHHHHHHHH | 36.08 | - | |
| 420 | Phosphorylation | EKLVDEKTILETSFH HHHCCHHHHHHHHHH | 28.84 | 24732914 | |
| 424 | Phosphorylation | DEKTILETSFHQHRE CHHHHHHHHHHHHHH | 32.99 | 30266825 | |
| 425 | Phosphorylation | EKTILETSFHQHRER HHHHHHHHHHHHHHH | 16.03 | 30266825 | |
| 425 (in isoform 2) | Phosphorylation | - | 16.03 | - | |
| 437 | Phosphorylation | RERAEQLSQENEKLM HHHHHHHHHHHHHHH | 34.83 | 21815630 | |
| 442 | Ubiquitination | QLSQENEKLMNLLQE HHHHHHHHHHHHHHH | 65.70 | - | |
| 452 | Ubiquitination | NLLQERVKNEEPTTQ HHHHHHHHCCCCCCC | 65.93 | - | |
| 462 | Acetylation | EPTTQEGKIIELEQK CCCCCCCCEEEHHHH | 39.49 | 26051181 | |
| 462 | Ubiquitination | EPTTQEGKIIELEQK CCCCCCCCEEEHHHH | 39.49 | - | |
| 469 | Ubiquitination | KIIELEQKCTGILEQ CEEEHHHHHHHHHHC | 25.12 | - | |
| 497 | Acetylation | QLTCSLRKVEEENQG HHHHHHHHHHHHCHH | 60.33 | 26051181 | |
| 518 | Ubiquitination | RLKEENEKLNEFLEL HHHHHHHHHHHHHHH | 69.10 | - | |
| 535 | Ubiquitination | HNNNMMAKTLEECRV HCCCHHHHHHHHHCH | 35.43 | - | |
| 562 | 2-Hydroxyisobutyrylation | KSHLQGEKQKATEAS HHHHCCHHHHHHHHH | 65.01 | - | |
| 573 (in isoform 3) | Phosphorylation | - | 39.14 | - | |
| 573 (in isoform 4) | Phosphorylation | - | 39.14 | - | |
| 591 | Ubiquitination | LKVARAEKDLLELSC HHHHHHHHHHHHHHH | 53.33 | - | |
| 597 | Phosphorylation | EKDLLELSCNELRQE HHHHHHHHHHHHHHH | 12.91 | 21815630 | |
| 616 | Phosphorylation | NGEIKHVSSLLAKVE CCCHHCHHHHHHHHH | 18.26 | 30108239 | |
| 617 | Phosphorylation | GEIKHVSSLLAKVEK CCHHCHHHHHHHHHH | 26.72 | 30108239 | |
| 624 | Ubiquitination | SLLAKVEKDYSYLKE HHHHHHHHCHHHHHH | 66.02 | - | |
| 626 | Phosphorylation | LAKVEKDYSYLKEIC HHHHHHCHHHHHHHH | 15.41 | 25884760 | |
| 628 | Phosphorylation | KVEKDYSYLKEICDH HHHHCHHHHHHHHHH | 18.63 | 25884760 | |
| 630 | 2-Hydroxyisobutyrylation | EKDYSYLKEICDHQA HHCHHHHHHHHHHHH | 36.48 | - | |
| 630 | Ubiquitination | EKDYSYLKEICDHQA HHCHHHHHHHHHHHH | 36.48 | - | |
| 646 | Ubiquitination | QLSRTSLKLQEKASE HHHHHHHHHHHHHCC | 48.14 | - | |
| 652 | Phosphorylation | LKLQEKASESDAEIK HHHHHHHCCCHHHHH | 49.02 | 30108239 | |
| 654 | Phosphorylation | LQEKASESDAEIKDM HHHHHCCCHHHHHHH | 39.36 | 27794612 | |
| 654 (in isoform 2) | Phosphorylation | - | 39.36 | - | |
| 679 | Ubiquitination | VEQHRAVKLHNNQLI HHHHHHHHHHCCHHH | 42.94 | - | |
| 692 | Phosphorylation | LISELESSVIKLEEQ HHHHHHHHHHHHHHH | 20.63 | 28555341 | |
| 695 | Ubiquitination | ELESSVIKLEEQKSD HHHHHHHHHHHHHHH | 47.92 | - | |
| 704 (in isoform 3) | Phosphorylation | - | 43.29 | 20068231 | |
| 707 (in isoform 3) | Phosphorylation | - | 5.99 | 20068231 | |
| 709 (in isoform 3) | Phosphorylation | - | 48.53 | 25159151 | |
| 718 | O-linked_Glycosylation | TKQMKEETEEWRRFQ HHHHHHHHHHHHHHH | 40.05 | 30379171 | |
| 728 (in isoform 4) | Phosphorylation | - | 5.66 | - | |
| 729 (in isoform 4) | Phosphorylation | - | 28.14 | - | |
| 739 | Ubiquitination | VVVANDIKCEAQQEL EEECCCHHCHHHHHH | 28.96 | - | |
| 745 (in isoform 4) | Phosphorylation | - | 28.30 | - | |
| 763 (in isoform 4) | Phosphorylation | - | 8.73 | - | |
| 765 | Ubiquitination | EKNARLQKELGDVQG HHHHHHHHHHCCCCC | 60.54 | - | |
| 766 (in isoform 4) | Phosphorylation | - | 45.05 | - | |
| 779 | Phosphorylation | GHGRVVTSRAAPPPV CCCEEEECCCCCCCC | 14.33 | 24719451 | |
| 782 (in isoform 4) | Phosphorylation | - | 18.93 | - | |
| 785 (in isoform 2) | Phosphorylation | - | 45.17 | 20068231 | |
| 788 (in isoform 2) | Phosphorylation | - | 75.56 | 20068231 | |
| 790 (in isoform 2) | Phosphorylation | - | 44.73 | 25159151 | |
| 792 | Phosphorylation | PVDEEPESSEVDAAG CCCCCCCCCCCCCCC | 42.38 | 27174698 | |
| 793 | Phosphorylation | VDEEPESSEVDAAGR CCCCCCCCCCCCCCC | 39.72 | 27174698 | |
| 807 | Phosphorylation | RWPGVCVSRTSPTPP CCCCEEEECCCCCCC | 25.39 | 25159151 | |
| 809 | Phosphorylation | PGVCVSRTSPTPPES CCEEEECCCCCCCCH | 31.39 | 30266825 | |
| 810 | Phosphorylation | GVCVSRTSPTPPESA CEEEECCCCCCCCHH | 26.18 | 22167270 | |
| 812 | Phosphorylation | CVSRTSPTPPESATT EEECCCCCCCCHHHH | 51.77 | 22167270 | |
| 816 | Phosphorylation | TSPTPPESATTVKSL CCCCCCCHHHHHHHH | 36.37 | 23403867 | |
| 816 (in isoform 4) | Ubiquitination | - | 36.37 | 21906983 | |
| 818 | Phosphorylation | PTPPESATTVKSLIK CCCCCHHHHHHHHHH | 41.21 | 23403867 | |
| 819 | Phosphorylation | TPPESATTVKSLIKS CCCCHHHHHHHHHHH | 26.17 | 27174698 | |
| 822 | Phosphorylation | ESATTVKSLIKSFDL CHHHHHHHHHHHCCC | 30.87 | 24719451 | |
| 826 | Phosphorylation | TVKSLIKSFDLGRPG HHHHHHHHCCCCCCC | 19.59 | 20068231 | |
| 831 (in isoform 4) | Phosphorylation | - | 33.71 | - | |
| 840 | Phosphorylation | GGAGQNISVHKTPRS CCCCCCCEEECCCCC | 26.22 | 24732914 | |
| 844 | Phosphorylation | QNISVHKTPRSPLSG CCCEEECCCCCCCCC | 14.73 | 22617229 | |
| 847 | Phosphorylation | SVHKTPRSPLSGIPV EEECCCCCCCCCCCC | 31.25 | 19664994 | |
| 850 | Phosphorylation | KTPRSPLSGIPVRTA CCCCCCCCCCCCCCC | 37.75 | 30266825 | |
| 856 | Phosphorylation | LSGIPVRTAPAAAVS CCCCCCCCCCCCCCC | 36.91 | 21815630 | |
| 863 | Phosphorylation | TAPAAAVSPMQRHST CCCCCCCCCCCCCCC | 15.21 | 25159151 | |
| 870 | Phosphorylation | SPMQRHSTYSSVRPA CCCCCCCCCCCCCCC | 22.69 | 28555341 | |
| 871 | Phosphorylation | PMQRHSTYSSVRPAS CCCCCCCCCCCCCCC | 11.27 | 28985074 | |
| 872 | Phosphorylation | MQRHSTYSSVRPASR CCCCCCCCCCCCCCC | 23.57 | 30576142 | |
| 873 | Phosphorylation | QRHSTYSSVRPASRG CCCCCCCCCCCCCCC | 16.25 | 30576142 | |
| 878 | Phosphorylation | YSSVRPASRGVTQRL CCCCCCCCCCCCCCC | 32.05 | 26330541 | |
| 897 | Ubiquitination | LPLSDILKGRTETLK CCHHHHHCCCCCCCC | 46.83 | 2190698 | |
| 897 (in isoform 1) | Ubiquitination | - | 46.83 | 21906983 | |
| 904 | Ubiquitination | KGRTETLKPDPHLRK CCCCCCCCCCCCCCC | 55.59 | - | |
| 911 | Ubiquitination | KPDPHLRKSPSLESL CCCCCCCCCCCHHHC | 73.42 | - | |
| 912 | Phosphorylation | PDPHLRKSPSLESLS CCCCCCCCCCHHHCC | 17.18 | 30266825 | |
| 914 | Phosphorylation | PHLRKSPSLESLSRP CCCCCCCCHHHCCCC | 52.43 | 22167270 | |
| 917 | Phosphorylation | RKSPSLESLSRPPSL CCCCCHHHCCCCCCC | 36.62 | 30266825 | |
| 919 | Phosphorylation | SPSLESLSRPPSLGF CCCHHHCCCCCCCCC | 52.61 | 25159151 | |
| 923 | Phosphorylation | ESLSRPPSLGFGDTR HHCCCCCCCCCCCHH | 43.75 | 25159151 | |
| 929 | Phosphorylation | PSLGFGDTRLLSAST CCCCCCCHHCCCCCC | 24.48 | 24732914 | |
| 933 | Phosphorylation | FGDTRLLSASTRAWK CCCHHCCCCCCCCCC | 25.43 | 23312004 | |
| 935 | Phosphorylation | DTRLLSASTRAWKPQ CHHCCCCCCCCCCCC | 18.30 | 24719451 | |
| 936 | Phosphorylation | TRLLSASTRAWKPQS HHCCCCCCCCCCCCC | 24.91 | 20068231 | |
| 940 | Ubiquitination | SASTRAWKPQSKLSV CCCCCCCCCCCCCCC | 31.99 | - | |
| 943 | Phosphorylation | TRAWKPQSKLSVERK CCCCCCCCCCCCCCC | 44.05 | 29978859 | |
| 946 | Phosphorylation | WKPQSKLSVERKDPL CCCCCCCCCCCCCHH | 26.18 | 29978859 | |
| 950 | Ubiquitination | SKLSVERKDPLAALA CCCCCCCCCHHHHHH | 50.63 | - | |
| 964 | Acetylation | AREYGGSKRNALLKW HHHHCCHHHHHHHHH | 53.60 | 20167786 | |
| 970 | Acetylation | SKRNALLKWCQKKTQ HHHHHHHHHHHHHCC | 46.93 | 20167786 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CYTSB_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CYTSB_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CYTSB_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DAXX_HUMAN | DAXX | physical | 22170762 | |
| TRAF2_HUMAN | TRAF2 | physical | 22170762 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-131; SER-134; THR-136;THR-140; THR-142; SER-360 AND SER-810, AND MASS SPECTROMETRY. | |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-131; SER-134; SER-138;THR-142; SER-218; SER-847; SER-863 AND SER-912, AND MASS SPECTROMETRY. | |
| "Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-847, AND MASSSPECTROMETRY. | |
| "Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-360; SER-361 ANDSER-366, AND MASS SPECTROMETRY. | |
