FA71B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FA71B_HUMAN
• UniProt AC: Q8TC56
• Protein Name: Protein FAM71B
• Gene Name: FAM71B
• Organism: Homo sapiens (Human).
• Sequence Length: 605
• Subcellular Localization: Nucleus . Cajal body and speckle localization.
• Protein Description: May be involved in RNA biogenesis..
• Protein Sequence: MSNESCLPYYTAHSYSSMSAFKTSMGDLQRQLYNRGEYNIFKYAPMFESNFIQINKKGEVIDVHNRVRMVTVGIVCTSPILPLPDVMVLAQPTKICEQHVRWGRFAKGRGRRPVKTLELTRLLPLKFVKISIHDHEKQQLRLKLATGRTFYLQLCPSSDTREDLFCYWEKLVYLLRPPVESYCSTPTLLSGDAPPEDNKSLVAAELHREGDQSETGLYKPCDVSAATSSAYAGGEGIQHASHGTASAASPSTSTPGAAEGGAARTAGGMAVAGTATGPRTDVAIAGAAMSPATGAMSIATTKSAGPGQVTTALAGAAIKNPGENESSKSMAGAANISSEGISLALVGAASTSLEGTSTSMAGAASLSQDSSLSAAFAGSITTSKCAAERTEGPAVGPLISTLQSEGYMSERDGSQKVSQPSAEVWNENKERREKKDRHPSRKSSHHRKAGESHRRRAGDKNQKASSHRSASGHKNTRDDKKEKGYSNVRGKRHGSSRKSSTHSSTKKESRTTQELGKNQSASSTGALQKKASKISSFLRSLRATPGSKTRVTSHDREVDIVAKMVEKQNIEAKVEKAQGGQELEMISGTMTSEKTEMIVFETKSI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSNESCLPY ------CCCCCCCCC	49.67	25693802
5	Phosphorylation	---MSNESCLPYYTA ---CCCCCCCCCCCC	25.79	25693802
9	Phosphorylation	SNESCLPYYTAHSYS CCCCCCCCCCCCCCC	10.66	25693802
10	Phosphorylation	NESCLPYYTAHSYSS CCCCCCCCCCCCCCC	8.77	25693802
11	Phosphorylation	ESCLPYYTAHSYSSM CCCCCCCCCCCCCCH	16.43	25693802
14	Phosphorylation	LPYYTAHSYSSMSAF CCCCCCCCCCCHHHH	25.01	25693802
15	Phosphorylation	PYYTAHSYSSMSAFK CCCCCCCCCCHHHHH	8.56	25693802
16	Phosphorylation	YYTAHSYSSMSAFKT CCCCCCCCCHHHHHC	23.68	25693802
17	Phosphorylation	YTAHSYSSMSAFKTS CCCCCCCCHHHHHCC	14.44	25693802
19	Phosphorylation	AHSYSSMSAFKTSMG CCCCCCHHHHHCCHH	32.28	25693802
23	Phosphorylation	SSMSAFKTSMGDLQR CCHHHHHCCHHHHHH	19.93	30622161
24	Phosphorylation	SMSAFKTSMGDLQRQ CHHHHHCCHHHHHHH	22.74	30622161
42	Acetylation	RGEYNIFKYAPMFES HCCCCHHHCCCCCCC	36.38	25038526
43	Phosphorylation	GEYNIFKYAPMFESN CCCCHHHCCCCCCCC	12.75	-
49	Phosphorylation	KYAPMFESNFIQINK HCCCCCCCCEEEECC	26.27	30622161
131	Phosphorylation	PLKFVKISIHDHEKQ EEEEEEEEECCHHHH	14.25	30622161
173	Phosphorylation	CYWEKLVYLLRPPVE HHHHHHHHHHCCCHH	15.51	25693802
181	Phosphorylation	LLRPPVESYCSTPTL HHCCCHHHHCCCCCE	31.50	30622161
182	Phosphorylation	LRPPVESYCSTPTLL HCCCHHHHCCCCCEE	4.12	30622161
184	Phosphorylation	PPVESYCSTPTLLSG CCHHHHCCCCCEECC	29.23	30622161
185	Phosphorylation	PVESYCSTPTLLSGD CHHHHCCCCCEECCC	19.41	30622161
187	Phosphorylation	ESYCSTPTLLSGDAP HHHCCCCCEECCCCC	40.18	30622161
190	Phosphorylation	CSTPTLLSGDAPPED CCCCCEECCCCCCCC	37.43	30622161
200	Phosphorylation	APPEDNKSLVAAELH CCCCCCCHHEEEEHH	34.04	30622161
213	Phosphorylation	LHREGDQSETGLYKP HHCCCCCCCCCCCCC	41.69	30622161
215	Phosphorylation	REGDQSETGLYKPCD CCCCCCCCCCCCCCC	37.42	30622161
265	Phosphorylation	AEGGAARTAGGMAVA CCCCCCCCCCCEEEE	25.57	28674151
274	Phosphorylation	GGMAVAGTATGPRTD CCEEEECCCCCCCCC	16.00	28674151
280	Phosphorylation	GTATGPRTDVAIAGA CCCCCCCCCEEEEHH	37.65	-
290	Phosphorylation	AIAGAAMSPATGAMS EEEHHHCCCCCCCCE	13.47	22210691
293	Phosphorylation	GAAMSPATGAMSIAT HHHCCCCCCCCEECC	28.94	25693802
297	Phosphorylation	SPATGAMSIATTKSA CCCCCCCEECCCCCC	14.45	25693802
301	Phosphorylation	GAMSIATTKSAGPGQ CCCEECCCCCCCCCH	17.61	-
303	Phosphorylation	MSIATTKSAGPGQVT CEECCCCCCCCCHHH	36.04	30622161
310	Phosphorylation	SAGPGQVTTALAGAA CCCCCHHHHHEEECE	9.85	25693802
311	Phosphorylation	AGPGQVTTALAGAAI CCCCHHHHHEEECEE	22.33	25693802
326	Phosphorylation	KNPGENESSKSMAGA CCCCCCCCHHHHCHH	55.43	25693802
327	Phosphorylation	NPGENESSKSMAGAA CCCCCCCHHHHCHHH	23.67	25693802
400	Phosphorylation	PAVGPLISTLQSEGY CCCHHHHHHHHHCCC	30.65	30622161
401	Phosphorylation	AVGPLISTLQSEGYM CCHHHHHHHHHCCCC	23.09	25693802
404	Phosphorylation	PLISTLQSEGYMSER HHHHHHHHCCCCCCC	35.78	30622161
407	Phosphorylation	STLQSEGYMSERDGS HHHHHCCCCCCCCCC	8.07	25693802
409	Phosphorylation	LQSEGYMSERDGSQK HHHCCCCCCCCCCCC	22.46	30622161
414	Phosphorylation	YMSERDGSQKVSQPS CCCCCCCCCCCCCCC	30.99	30622161
421	Phosphorylation	SQKVSQPSAEVWNEN CCCCCCCCHHHHHHH	29.44	30622161
440	Phosphorylation	EKKDRHPSRKSSHHR HHHHCCCCCHHHHHH	46.33	23532336
443	Phosphorylation	DRHPSRKSSHHRKAG HCCCCCHHHHHHHHH	33.52	-
444	Phosphorylation	RHPSRKSSHHRKAGE CCCCCHHHHHHHHHH	26.75	-
466	Phosphorylation	DKNQKASSHRSASGH CCCHHHHHCCCCCCC	27.98	-
485	Phosphorylation	DDKKEKGYSNVRGKR HHHHHHCCCCCCCCC	14.24	24719451
486	Phosphorylation	DKKEKGYSNVRGKRH HHHHHCCCCCCCCCC	37.20	24719451
495	Phosphorylation	VRGKRHGSSRKSSTH CCCCCCCCCCCCCCC	22.35	29083192
496	Phosphorylation	RGKRHGSSRKSSTHS CCCCCCCCCCCCCCC	48.60	29083192
499	Phosphorylation	RHGSSRKSSTHSSTK CCCCCCCCCCCCCCC	39.08	29083192
500	Phosphorylation	HGSSRKSSTHSSTKK CCCCCCCCCCCCCCC	32.92	29759185
501	Phosphorylation	GSSRKSSTHSSTKKE CCCCCCCCCCCCCCC	32.63	29759185
503	Phosphorylation	SRKSSTHSSTKKESR CCCCCCCCCCCCCCC	39.53	23836654
504	Phosphorylation	RKSSTHSSTKKESRT CCCCCCCCCCCCCCC	36.32	23836654
505	Phosphorylation	KSSTHSSTKKESRTT CCCCCCCCCCCCCCH	49.50	23836654
509	Phosphorylation	HSSTKKESRTTQELG CCCCCCCCCCHHHHC	43.75	30622161
511	Phosphorylation	STKKESRTTQELGKN CCCCCCCCHHHHCCC	41.95	30622161
512	Phosphorylation	TKKESRTTQELGKNQ CCCCCCCHHHHCCCC	20.95	30622161
520	Phosphorylation	QELGKNQSASSTGAL HHHCCCCCCCHHHHH	39.24	30622161
520	O-linked_Glycosylation	QELGKNQSASSTGAL HHHCCCCCCCHHHHH	39.24	30379171
522	Phosphorylation	LGKNQSASSTGALQK HCCCCCCCHHHHHHH	33.41	30622161
523	Phosphorylation	GKNQSASSTGALQKK CCCCCCCHHHHHHHH	30.49	30622161
524	Phosphorylation	KNQSASSTGALQKKA CCCCCCHHHHHHHHH	24.79	30622161
532	Phosphorylation	GALQKKASKISSFLR HHHHHHHHHHHHHHH	39.13	30622161
535	Phosphorylation	QKKASKISSFLRSLR HHHHHHHHHHHHHHH	20.83	30622161
536	Phosphorylation	KKASKISSFLRSLRA HHHHHHHHHHHHHHC	31.60	24719451
544	Phosphorylation	FLRSLRATPGSKTRV HHHHHHCCCCCCCCC	23.04	22985185
547	Phosphorylation	SLRATPGSKTRVTSH HHHCCCCCCCCCCCC	31.86	22985185
552	Phosphorylation	PGSKTRVTSHDREVD CCCCCCCCCCCHHHH	19.63	30622161
553	Phosphorylation	GSKTRVTSHDREVDI CCCCCCCCCCHHHHH	22.12	30622161
587	Phosphorylation	GQELEMISGTMTSEK CCEEEEEEEECCCCC	27.22	25693802
589	Phosphorylation	ELEMISGTMTSEKTE EEEEEEEECCCCCEE	15.53	29978859
591	Phosphorylation	EMISGTMTSEKTEMI EEEEEECCCCCEEEE	33.31	22210691
592	Phosphorylation	MISGTMTSEKTEMIV EEEEECCCCCEEEEE	26.69	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FA71B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FA71B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FA71B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FA71B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.