UniProt ID | PB1_HUMAN | |
---|---|---|
UniProt AC | Q86U86 | |
Protein Name | Protein polybromo-1 | |
Gene Name | PBRM1 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 1689 | |
Subcellular Localization | Nucleus . | |
Protein Description | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.. | |
Protein Sequence | MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLMLRDTLNIRQAYNLENV | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
9 | Phosphorylation | GSKRRRATSPSSSVS CCCCCCCCCCCCCCC | 39.08 | 29255136 | |
9 (in isoform 3) | Phosphorylation | - | 39.08 | - | |
9 (in isoform 4) | Phosphorylation | - | 39.08 | - | |
9 (in isoform 5) | Phosphorylation | - | 39.08 | 24719451 | |
9 (in isoform 6) | Phosphorylation | - | 39.08 | - | |
10 | Phosphorylation | SKRRRATSPSSSVSG CCCCCCCCCCCCCCC | 23.07 | 29255136 | |
10 (in isoform 3) | Phosphorylation | - | 23.07 | - | |
10 (in isoform 4) | Phosphorylation | - | 23.07 | 27251275 | |
10 (in isoform 5) | Phosphorylation | - | 23.07 | - | |
10 (in isoform 6) | Phosphorylation | - | 23.07 | - | |
12 | Phosphorylation | RRRATSPSSSVSGDF CCCCCCCCCCCCCCC | 34.70 | 29255136 | |
12 (in isoform 3) | Phosphorylation | - | 34.70 | - | |
12 (in isoform 4) | Phosphorylation | - | 34.70 | - | |
12 (in isoform 5) | Phosphorylation | - | 34.70 | 24719451 | |
12 (in isoform 6) | Phosphorylation | - | 34.70 | - | |
13 | Phosphorylation | RRATSPSSSVSGDFD CCCCCCCCCCCCCCC | 37.84 | 29255136 | |
13 (in isoform 4) | Phosphorylation | - | 37.84 | 27251275 | |
13 (in isoform 5) | Phosphorylation | - | 37.84 | 24719451 | |
14 | Phosphorylation | RATSPSSSVSGDFDD CCCCCCCCCCCCCCC | 25.33 | 29255136 | |
14 (in isoform 3) | Phosphorylation | - | 25.33 | - | |
14 (in isoform 4) | Phosphorylation | - | 25.33 | 27251275 | |
14 (in isoform 5) | Phosphorylation | - | 25.33 | 24719451 | |
14 (in isoform 6) | Phosphorylation | - | 25.33 | - | |
16 | Phosphorylation | TSPSSSVSGDFDDGH CCCCCCCCCCCCCCC | 34.29 | 29255136 | |
16 (in isoform 3) | Phosphorylation | - | 34.29 | - | |
16 (in isoform 4) | Phosphorylation | - | 34.29 | 27251275 | |
16 (in isoform 5) | Phosphorylation | - | 34.29 | - | |
16 (in isoform 6) | Phosphorylation | - | 34.29 | - | |
25 | Phosphorylation | DFDDGHHSVSTPGPS CCCCCCCCCCCCCCC | 16.46 | 22167270 | |
25 (in isoform 3) | Phosphorylation | - | 16.46 | - | |
25 (in isoform 4) | Phosphorylation | - | 16.46 | 27251275 | |
25 (in isoform 5) | Phosphorylation | - | 16.46 | - | |
25 (in isoform 6) | Phosphorylation | - | 16.46 | - | |
26 | Phosphorylation | FDDGHHSVSTPGPSR CCCCCCCCCCCCCCH | 6.84 | 32142685 | |
27 | Phosphorylation | DDGHHSVSTPGPSRK CCCCCCCCCCCCCHH | 31.72 | 22167270 | |
28 | Phosphorylation | DGHHSVSTPGPSRKR CCCCCCCCCCCCHHC | 30.06 | 22167270 | |
28 (in isoform 3) | Phosphorylation | - | 30.06 | - | |
28 (in isoform 4) | Phosphorylation | - | 30.06 | - | |
28 (in isoform 5) | Phosphorylation | - | 30.06 | - | |
28 (in isoform 6) | Phosphorylation | - | 30.06 | - | |
30 | Phosphorylation | HHSVSTPGPSRKRRR CCCCCCCCCCHHCHH | 32.67 | 32142685 | |
31 | Phosphorylation | HSVSTPGPSRKRRRL CCCCCCCCCHHCHHH | 31.97 | 33259812 | |
32 | Phosphorylation | SVSTPGPSRKRRRLS CCCCCCCCHHCHHHH | 57.24 | 22167270 | |
33 | Phosphorylation | VSTPGPSRKRRRLSN CCCCCCCHHCHHHHC | 39.37 | 32142685 | |
34 | Phosphorylation | STPGPSRKRRRLSNL CCCCCCHHCHHHHCC | 55.37 | 32142685 | |
35 | Phosphorylation | TPGPSRKRRRLSNLP CCCCCHHCHHHHCCC | 28.04 | 33259812 | |
37 | Phosphorylation | GPSRKRRRLSNLPTV CCCHHCHHHHCCCCC | 46.64 | 32142685 | |
39 | Phosphorylation | SRKRRRLSNLPTVDP CHHCHHHHCCCCCCH | 34.21 | 25159151 | |
39 (in isoform 3) | Phosphorylation | - | 34.21 | - | |
39 (in isoform 4) | Phosphorylation | - | 34.21 | 27251275 | |
39 (in isoform 5) | Phosphorylation | - | 34.21 | 24719451 | |
39 (in isoform 6) | Phosphorylation | - | 34.21 | - | |
43 | Phosphorylation | RRLSNLPTVDPIAVC HHHHCCCCCCHHHHH | 40.48 | 22617229 | |
54 | Phosphorylation | IAVCHELYNTIRDYK HHHHHHHHHHHHHCC | 13.79 | 21082442 | |
54 (in isoform 3) | Phosphorylation | - | 13.79 | - | |
54 (in isoform 4) | Phosphorylation | - | 13.79 | - | |
54 (in isoform 5) | Phosphorylation | - | 13.79 | - | |
56 | Phosphorylation | VCHELYNTIRDYKDE HHHHHHHHHHHCCCH | 12.11 | 24732914 | |
57 | Phosphorylation | CHELYNTIRDYKDEQ HHHHHHHHHHCCCHH | 2.55 | 32645325 | |
60 | Phosphorylation | LYNTIRDYKDEQGRL HHHHHHHCCCHHHCH | 15.53 | 32645325 | |
84 | Phosphorylation | KRRNQPDYYEVVSQP CCCCCCCHHHHHCCC | 14.28 | 27642862 | |
85 | Phosphorylation | RRNQPDYYEVVSQPI CCCCCCHHHHHCCCC | 15.04 | 27642862 | |
89 | Phosphorylation | PDYYEVVSQPIDLMK CCHHHHHCCCCCHHH | 35.10 | 27050516 | |
96 | Sumoylation | SQPIDLMKIQQKLKM CCCCCHHHHHHHHCC | 44.66 | 28112733 | |
96 | Ubiquitination | SQPIDLMKIQQKLKM CCCCCHHHHHHHHCC | 44.66 | 29967540 | |
125 | Phosphorylation | LLFNNAKSYYKPDSP HHHCCCHHHCCCCCH | 31.14 | 29396449 | |
125 (in isoform 5) | Phosphorylation | - | 31.14 | 24719451 | |
127 | Phosphorylation | FNNAKSYYKPDSPEY HCCCHHHCCCCCHHH | 24.12 | 29396449 | |
127 (in isoform 5) | Phosphorylation | - | 24.12 | 24719451 | |
128 | Ubiquitination | NNAKSYYKPDSPEYK CCCHHHCCCCCHHHH | 33.83 | 29967540 | |
131 | Phosphorylation | KSYYKPDSPEYKAAC HHHCCCCCHHHHHHH | 28.32 | 25159151 | |
131 (in isoform 3) | Phosphorylation | - | 28.32 | - | |
131 (in isoform 4) | Phosphorylation | - | 28.32 | 27251275 | |
131 (in isoform 5) | Phosphorylation | - | 28.32 | 24719451 | |
131 (in isoform 6) | Phosphorylation | - | 28.32 | - | |
134 | Phosphorylation | YKPDSPEYKAACKLW CCCCCHHHHHHHHHH | 14.87 | 29396449 | |
135 | Acetylation | KPDSPEYKAACKLWD CCCCHHHHHHHHHHH | 28.04 | 25953088 | |
139 | Acetylation | PEYKAACKLWDLYLR HHHHHHHHHHHHHHH | 48.13 | 26051181 | |
154 | Sumoylation | TRNEFVQKGEADDED HHHHHHHCCCCCCCC | 54.11 | 28112733 | |
154 | Ubiquitination | TRNEFVQKGEADDED HHHHHHHCCCCCCCC | 54.11 | 29967540 | |
172 | Phosphorylation | DGQDNQGTVTEGSSP CCCCCCCCCCCCCCH | 17.94 | 28450419 | |
174 | Phosphorylation | QDNQGTVTEGSSPAY CCCCCCCCCCCCHHH | 34.17 | 30278072 | |
177 | Phosphorylation | QGTVTEGSSPAYLKE CCCCCCCCCHHHHHH | 27.24 | 30278072 | |
178 | Phosphorylation | GTVTEGSSPAYLKEI CCCCCCCCHHHHHHH | 25.14 | 30278072 | |
178 (in isoform 3) | Phosphorylation | - | 25.14 | - | |
178 (in isoform 4) | Phosphorylation | - | 25.14 | 27251275 | |
178 (in isoform 5) | Phosphorylation | - | 25.14 | 24719451 | |
178 (in isoform 6) | Phosphorylation | - | 25.14 | - | |
181 | Phosphorylation | TEGSSPAYLKEILEQ CCCCCHHHHHHHHHH | 22.99 | 21955146 | |
210 | Sumoylation | LISELFQKLPSKVQY HHHHHHHHCCCCCCC | 55.84 | 28112733 | |
213 | Phosphorylation | ELFQKLPSKVQYPDY HHHHHCCCCCCCCCC | 56.76 | 24719451 | |
214 | Ubiquitination | LFQKLPSKVQYPDYY HHHHCCCCCCCCCCE | 31.27 | 29967540 | |
225 | Ubiquitination | PDYYAIIKEPIDLKT CCCEEEECCCCCHHH | 51.85 | 29967540 | |
231 | Ubiquitination | IKEPIDLKTIAQRIQ ECCCCCHHHHHHHHH | 33.85 | 29967540 | |
232 | Phosphorylation | KEPIDLKTIAQRIQN CCCCCHHHHHHHHHC | 28.92 | - | |
241 | Phosphorylation | AQRIQNGSYKSIHAM HHHHHCCCHHHHHHH | 36.62 | 28450419 | |
242 | Phosphorylation | QRIQNGSYKSIHAMA HHHHCCCHHHHHHHH | 15.34 | 28450419 | |
244 | Phosphorylation | IQNGSYKSIHAMAKD HHCCCHHHHHHHHHH | 16.04 | 28450419 | |
250 | Acetylation | KSIHAMAKDIDLLAK HHHHHHHHHHHHHHH | 41.97 | 26051181 | |
250 | Ubiquitination | KSIHAMAKDIDLLAK HHHHHHHHHHHHHHH | 41.97 | 29967540 | |
257 | Ubiquitination | KDIDLLAKNAKTYNE HHHHHHHHHCCCCCC | 58.36 | 29967540 | |
260 | Ubiquitination | DLLAKNAKTYNEPGS HHHHHHCCCCCCCCC | 62.02 | 29967540 | |
294 | Ubiquitination | IEHHEMAKSSLRMRT HCCHHHHHHHHHCCC | 38.99 | 29967540 | |
295 | Phosphorylation | EHHEMAKSSLRMRTP CCHHHHHHHHHCCCH | 25.68 | 29214152 | |
301 | Phosphorylation | KSSLRMRTPSNLAAA HHHHHCCCHHHHHHH | 23.02 | 30266825 | |
301 (in isoform 4) | Phosphorylation | - | 23.02 | 27251275 | |
301 (in isoform 5) | Phosphorylation | - | 23.02 | 24719451 | |
301 (in isoform 6) | Phosphorylation | - | 23.02 | - | |
303 | Phosphorylation | SLRMRTPSNLAAARL HHHCCCHHHHHHHHH | 43.81 | 30266825 | |
303 (in isoform 4) | Phosphorylation | - | 43.81 | - | |
303 (in isoform 5) | Phosphorylation | - | 43.81 | - | |
303 (in isoform 6) | Phosphorylation | - | 43.81 | - | |
311 | Phosphorylation | NLAAARLTGPSHSKG HHHHHHHHCCCCCCC | 41.30 | 24732914 | |
311 (in isoform 3) | Phosphorylation | - | 41.30 | - | |
314 | Phosphorylation | AARLTGPSHSKGSLG HHHHHCCCCCCCCCC | 41.56 | 26055452 | |
314 (in isoform 3) | Phosphorylation | - | 41.56 | - | |
314 (in isoform 4) | Phosphorylation | - | 41.56 | - | |
314 (in isoform 5) | Phosphorylation | - | 41.56 | - | |
314 (in isoform 6) | Phosphorylation | - | 41.56 | - | |
316 | Phosphorylation | RLTGPSHSKGSLGEE HHHCCCCCCCCCCCC | 42.95 | 26055452 | |
316 (in isoform 4) | Phosphorylation | - | 42.95 | 27251275 | |
316 (in isoform 5) | Phosphorylation | - | 42.95 | - | |
316 (in isoform 6) | Phosphorylation | - | 42.95 | - | |
317 | Ubiquitination | LTGPSHSKGSLGEER HHCCCCCCCCCCCCC | 47.28 | 24816145 | |
319 | Phosphorylation | GPSHSKGSLGEERNP CCCCCCCCCCCCCCC | 36.62 | 25159151 | |
319 (in isoform 3) | Phosphorylation | - | 36.62 | - | |
319 (in isoform 4) | Phosphorylation | - | 36.62 | 27251275 | |
319 (in isoform 5) | Phosphorylation | - | 36.62 | - | |
319 (in isoform 6) | Phosphorylation | - | 36.62 | - | |
321 (in isoform 3) | Phosphorylation | - | 36.09 | - | |
323 (in isoform 3) | Phosphorylation | - | 56.83 | - | |
326 | Ubiquitination | SLGEERNPTSKYYRN CCCCCCCCCCHHHHC | 44.25 | 24816145 | |
327 | Phosphorylation | LGEERNPTSKYYRNK CCCCCCCCCHHHHCH | 41.21 | 24732914 | |
328 | Phosphorylation | GEERNPTSKYYRNKR CCCCCCCCHHHHCHH | 21.66 | 24732914 | |
329 | "N6,N6-dimethyllysine" | EERNPTSKYYRNKRA CCCCCCCHHHHCHHH | 49.10 | - | |
329 | Methylation | EERNPTSKYYRNKRA CCCCCCCHHHHCHHH | 49.10 | - | |
329 | Ubiquitination | EERNPTSKYYRNKRA CCCCCCCHHHHCHHH | 49.10 | 29967540 | |
334 | Ubiquitination | TSKYYRNKRAVQGGR CCHHHHCHHHHHCCH | 32.51 | 24816145 | |
334 (in isoform 3) | Phosphorylation | - | 32.51 | - | |
335 | Ubiquitination | SKYYRNKRAVQGGRL CHHHHCHHHHHCCHH | 43.47 | 24816145 | |
338 | Ubiquitination | YRNKRAVQGGRLSAI HHCHHHHHCCHHHHH | 47.87 | 24816145 | |
339 | Phosphorylation | RNKRAVQGGRLSAIT HCHHHHHCCHHHHHH | 19.31 | 32142685 | |
339 (in isoform 3) | Phosphorylation | - | 19.31 | - | |
341 | Phosphorylation | KRAVQGGRLSAITMA HHHHHCCHHHHHHHH | 32.09 | 32142685 | |
343 | Phosphorylation | AVQGGRLSAITMALQ HHHCCHHHHHHHHHH | 19.10 | 28176443 | |
343 (in isoform 3) | Phosphorylation | - | 19.10 | - | |
343 (in isoform 4) | Phosphorylation | - | 19.10 | - | |
343 (in isoform 5) | Phosphorylation | - | 19.10 | - | |
343 (in isoform 6) | Phosphorylation | - | 19.10 | - | |
344 | Ubiquitination | VQGGRLSAITMALQY HHCCHHHHHHHHHHH | 13.08 | 24816145 | |
345 (in isoform 3) | Phosphorylation | - | 2.13 | - | |
346 | Phosphorylation | GGRLSAITMALQYGS CCHHHHHHHHHHHCC | 8.98 | 28176443 | |
346 (in isoform 4) | Phosphorylation | - | 8.98 | - | |
346 (in isoform 5) | Phosphorylation | - | 8.98 | - | |
346 (in isoform 6) | Phosphorylation | - | 8.98 | - | |
347 | Ubiquitination | GRLSAITMALQYGSE CHHHHHHHHHHHCCC | 2.61 | 24816145 | |
351 | Phosphorylation | AITMALQYGSESEED HHHHHHHHCCCCHHH | 24.38 | 28176443 | |
351 (in isoform 4) | Phosphorylation | - | 24.38 | - | |
351 (in isoform 5) | Phosphorylation | - | 24.38 | - | |
351 (in isoform 6) | Phosphorylation | - | 24.38 | - | |
353 | Phosphorylation | TMALQYGSESEEDAA HHHHHHCCCCHHHHH | 32.77 | 28176443 | |
353 (in isoform 4) | Phosphorylation | - | 32.77 | 27251275 | |
353 (in isoform 5) | Phosphorylation | - | 32.77 | - | |
353 (in isoform 6) | Phosphorylation | - | 32.77 | - | |
355 | Phosphorylation | ALQYGSESEEDAALA HHHHCCCCHHHHHHH | 48.24 | 28176443 | |
355 (in isoform 4) | Phosphorylation | - | 48.24 | 27251275 | |
355 (in isoform 5) | Phosphorylation | - | 48.24 | - | |
355 (in isoform 6) | Phosphorylation | - | 48.24 | - | |
366 | Phosphorylation | AALAAARYEEGESEA HHHHHHHHHCCCCHH | 17.38 | 22115753 | |
366 (in isoform 4) | Phosphorylation | - | 17.38 | - | |
366 (in isoform 5) | Phosphorylation | - | 17.38 | - | |
366 (in isoform 6) | Phosphorylation | - | 17.38 | - | |
370 | Phosphorylation | AARYEEGESEAESIT HHHHHCCCCHHHHHH | 49.00 | 32142685 | |
371 | Phosphorylation | ARYEEGESEAESITS HHHHCCCCHHHHHHH | 53.62 | 27362937 | |
371 (in isoform 4) | Phosphorylation | - | 53.62 | 27251275 | |
371 (in isoform 5) | Phosphorylation | - | 53.62 | 24719451 | |
371 (in isoform 6) | Phosphorylation | - | 53.62 | - | |
372 | Phosphorylation | RYEEGESEAESITSF HHHCCCCHHHHHHHH | 52.75 | 32142685 | |
373 | Phosphorylation | YEEGESEAESITSFM HHCCCCHHHHHHHHH | 25.72 | 32142685 | |
374 | Phosphorylation | EEGESEAESITSFMD HCCCCHHHHHHHHHC | 38.33 | 32142685 | |
375 | Phosphorylation | EGESEAESITSFMDV CCCCHHHHHHHHHCC | 37.91 | 27362937 | |
375 (in isoform 4) | Phosphorylation | - | 37.91 | 27251275 | |
375 (in isoform 5) | Phosphorylation | - | 37.91 | - | |
375 (in isoform 6) | Phosphorylation | - | 37.91 | - | |
376 | Phosphorylation | GESEAESITSFMDVS CCCHHHHHHHHHCCC | 2.55 | 32142685 | |
377 | Phosphorylation | ESEAESITSFMDVSN CCHHHHHHHHHCCCC | 25.78 | 22115753 | |
377 (in isoform 4) | Phosphorylation | - | 25.78 | - | |
377 (in isoform 5) | Phosphorylation | - | 25.78 | 24719451 | |
377 (in isoform 6) | Phosphorylation | - | 25.78 | - | |
378 | Phosphorylation | SEAESITSFMDVSNP CHHHHHHHHHCCCCH | 19.53 | 28464451 | |
383 | Phosphorylation | ITSFMDVSNPFYQLY HHHHHCCCCHHHHHH | 34.22 | 28464451 | |
387 | Phosphorylation | MDVSNPFYQLYDTVR HCCCCHHHHHHHHHH | 10.00 | 21406692 | |
390 | Phosphorylation | SNPFYQLYDTVRSCR CCHHHHHHHHHHHHH | 8.27 | 21406692 | |
392 | Phosphorylation | PFYQLYDTVRSCRNN HHHHHHHHHHHHHCC | 12.31 | 21406692 | |
413 | Phosphorylation | EPFYHLPSKKKYPDY ECEECCCCCCCCCCH | 64.56 | 24719451 | |
414 | Acetylation | PFYHLPSKKKYPDYY CEECCCCCCCCCCHH | 51.88 | 23749302 | |
415 | Acetylation | FYHLPSKKKYPDYYQ EECCCCCCCCCCHHH | 62.97 | 24848071 | |
425 | Sumoylation | PDYYQQIKMPISLQQ CCHHHHCCCCCCHHH | 34.00 | 28112733 | |
425 | Ubiquitination | PDYYQQIKMPISLQQ CCHHHHCCCCCCHHH | 34.00 | 29967540 | |
462 | Phosphorylation | MFENAKRYNVPNSAI HHCCHHHCCCCCHHH | 21.58 | 21406692 | |
466 (in isoform 3) | Phosphorylation | - | 39.53 | - | |
467 | Phosphorylation | KRYNVPNSAIYKRVL HHCCCCCHHHHHHHH | 15.24 | 21406692 | |
470 | Phosphorylation | NVPNSAIYKRVLKLQ CCCCHHHHHHHHHHH | 7.77 | 21406692 | |
471 | Sumoylation | VPNSAIYKRVLKLQQ CCCHHHHHHHHHHHH | 29.89 | 28112733 | |
475 | Acetylation | AIYKRVLKLQQVMQA HHHHHHHHHHHHHHH | 41.20 | 25953088 | |
475 (in isoform 3) | Phosphorylation | - | 41.20 | - | |
477 (in isoform 3) | Phosphorylation | - | 32.03 | - | |
498 | Phosphorylation | DDIEDGDSMISSATS CCCCCCCCHHHHHCC | 24.44 | 23401153 | |
498 (in isoform 4) | Phosphorylation | - | 24.44 | 27251275 | |
498 (in isoform 5) | Phosphorylation | - | 24.44 | - | |
498 (in isoform 6) | Phosphorylation | - | 24.44 | - | |
499 | Sulfoxidation | DIEDGDSMISSATSD CCCCCCCHHHHHCCC | 4.02 | 21406390 | |
501 | Phosphorylation | EDGDSMISSATSDTG CCCCCHHHHHCCCCC | 12.79 | 30266825 | |
501 (in isoform 7) | Phosphorylation | - | 12.79 | 25159151 | |
501 (in isoform 8) | Phosphorylation | - | 12.79 | 25159151 | |
502 | Phosphorylation | DGDSMISSATSDTGS CCCCHHHHHCCCCCC | 25.33 | 30266825 | |
502 (in isoform 4) | Phosphorylation | - | 25.33 | 27251275 | |
502 (in isoform 7) | Phosphorylation | - | 25.33 | 25159151 | |
502 (in isoform 8) | Phosphorylation | - | 25.33 | 25159151 | |
504 | Phosphorylation | DSMISSATSDTGSAK CCHHHHHCCCCCCCC | 29.14 | 30266825 | |
504 (in isoform 7) | Phosphorylation | - | 29.14 | 25627689 | |
504 (in isoform 8) | Phosphorylation | - | 29.14 | 25627689 | |
505 | Phosphorylation | SMISSATSDTGSAKR CHHHHHCCCCCCCCH | 32.65 | 23401153 | |
505 (in isoform 5) | Phosphorylation | - | 32.65 | 24719451 | |
505 (in isoform 7) | Phosphorylation | - | 32.65 | 25849741 | |
505 (in isoform 8) | Phosphorylation | - | 32.65 | 25849741 | |
507 | Phosphorylation | ISSATSDTGSAKRKS HHHHCCCCCCCCHHC | 32.57 | 30266825 | |
507 (in isoform 4) | Phosphorylation | - | 32.57 | 27251275 | |
507 (in isoform 5) | Phosphorylation | - | 32.57 | - | |
507 (in isoform 6) | Phosphorylation | - | 32.57 | - | |
507 (in isoform 7) | Phosphorylation | - | 32.57 | 25159151 | |
507 (in isoform 8) | Phosphorylation | - | 32.57 | 25159151 | |
509 | Phosphorylation | SATSDTGSAKRKSKK HHCCCCCCCCHHCHH | 32.48 | 30266825 | |
509 (in isoform 4) | Phosphorylation | - | 32.48 | - | |
509 (in isoform 5) | Phosphorylation | - | 32.48 | - | |
509 (in isoform 6) | Phosphorylation | - | 32.48 | - | |
509 (in isoform 7) | Phosphorylation | - | 32.48 | 25849741 | |
509 (in isoform 8) | Phosphorylation | - | 32.48 | 25849741 | |
511 | Acetylation | TSDTGSAKRKSKKNI CCCCCCCCHHCHHHH | 63.15 | 25953088 | |
511 | Sumoylation | TSDTGSAKRKSKKNI CCCCCCCCHHCHHHH | 63.15 | 28112733 | |
516 (in isoform 7) | Phosphorylation | - | 65.77 | 25159151 | |
516 (in isoform 8) | Phosphorylation | - | 65.77 | 25159151 | |
519 (in isoform 7) | Phosphorylation | - | 38.15 | 25159151 | |
519 (in isoform 8) | Phosphorylation | - | 38.15 | 25159151 | |
549 | Acetylation | LCDLFMVKPSKKDYP CEEEEEECCCCCCCC | 31.61 | 26051181 | |
569 | Acetylation | ILEPMDLKIIEHNIR EECCCCHHHHHHCCC | 37.06 | 7964249 | |
569 | Ubiquitination | ILEPMDLKIIEHNIR EECCCCHHHHHHCCC | 37.06 | 32015554 | |
570 | Ubiquitination | LEPMDLKIIEHNIRN ECCCCHHHHHHCCCC | 6.09 | 32015554 | |
579 | Acetylation | EHNIRNDKYAGEEGM HHCCCCCCCCCCCCC | 40.32 | 27452117 | |
579 | Ubiquitination | EHNIRNDKYAGEEGM HHCCCCCCCCCCCCC | 40.32 | - | |
586 | Ubiquitination | KYAGEEGMIEDMKLM CCCCCCCCHHHHHHH | 3.25 | 32015554 | |
587 | Ubiquitination | YAGEEGMIEDMKLMF CCCCCCCHHHHHHHH | 6.29 | 32015554 | |
590 | Ubiquitination | EEGMIEDMKLMFRNA CCCCHHHHHHHHHCC | 2.02 | 32015554 | |
591 | Sumoylation | EGMIEDMKLMFRNAR CCCHHHHHHHHHCCC | 49.47 | 28112733 | |
591 | Ubiquitination | EGMIEDMKLMFRNAR CCCHHHHHHHHHCCC | 49.47 | 32015554 | |
592 | Ubiquitination | GMIEDMKLMFRNARH CCHHHHHHHHHCCCC | 2.92 | 32015554 | |
602 | Ubiquitination | RNARHYNEEGSQVYN HCCCCCCCCCCHHHC | 57.48 | 32015554 | |
604 (in isoform 3) | Phosphorylation | - | 19.73 | - | |
605 | Phosphorylation | RHYNEEGSQVYNDAH CCCCCCCCHHHCHHH | 21.54 | 24247654 | |
605 | Ubiquitination | RHYNEEGSQVYNDAH CCCCCCCCHHHCHHH | 21.54 | 32015554 | |
608 | Ubiquitination | NEEGSQVYNDAHILE CCCCCHHHCHHHHHH | 10.33 | 32015554 | |
609 | Ubiquitination | EEGSQVYNDAHILEK CCCCHHHCHHHHHHH | 40.93 | 32015554 | |
612 | Ubiquitination | SQVYNDAHILEKLLK CHHHCHHHHHHHHHH | 28.20 | 32015554 | |
613 (in isoform 3) | Phosphorylation | - | 5.95 | - | |
616 | Acetylation | NDAHILEKLLKEKRK CHHHHHHHHHHHHHH | 56.53 | 25953088 | |
616 | Ubiquitination | NDAHILEKLLKEKRK CHHHHHHHHHHHHHH | 56.53 | 29967540 | |
616 (in isoform 3) | Phosphorylation | - | 56.53 | - | |
623 | Ubiquitination | KLLKEKRKELGPLPD HHHHHHHHHHCCCCC | 69.25 | 29967540 | |
624 | Ubiquitination | LLKEKRKELGPLPDD HHHHHHHHHCCCCCC | 64.09 | 32015554 | |
627 | Ubiquitination | EKRKELGPLPDDDDM HHHHHHCCCCCCCCC | 54.03 | 32015554 | |
634 | Sulfoxidation | PLPDDDDMASPKLKL CCCCCCCCCCCCHHH | 5.24 | 21406390 | |
636 | Phosphorylation | PDDDDMASPKLKLSR CCCCCCCCCCHHHHH | 18.87 | 25159151 | |
636 (in isoform 4) | Phosphorylation | - | 18.87 | 27251275 | |
636 (in isoform 5) | Phosphorylation | - | 18.87 | 24719451 | |
636 (in isoform 6) | Phosphorylation | - | 18.87 | - | |
638 | Sumoylation | DDDMASPKLKLSRKS CCCCCCCCHHHHHCC | 56.62 | 28112733 | |
642 | Phosphorylation | ASPKLKLSRKSGISP CCCCHHHHHCCCCCC | 35.75 | 30001349 | |
645 | Phosphorylation | KLKLSRKSGISPKKS CHHHHHCCCCCCCCC | 40.00 | 30266825 | |
645 (in isoform 4) | Phosphorylation | - | 40.00 | - | |
645 (in isoform 5) | Phosphorylation | - | 40.00 | - | |
645 (in isoform 6) | Phosphorylation | - | 40.00 | - | |
648 | Phosphorylation | LSRKSGISPKKSKYM HHHCCCCCCCCCCCC | 33.90 | 30266825 | |
648 (in isoform 4) | Phosphorylation | - | 33.90 | 27251275 | |
648 (in isoform 5) | Phosphorylation | - | 33.90 | 24719451 | |
648 (in isoform 6) | Phosphorylation | - | 33.90 | - | |
653 | Sumoylation | GISPKKSKYMTPMQQ CCCCCCCCCCCHHHH | 48.17 | 28112733 | |
654 | Phosphorylation | ISPKKSKYMTPMQQK CCCCCCCCCCHHHHH | 17.20 | 26552605 | |
656 | Phosphorylation | PKKSKYMTPMQQKLN CCCCCCCCHHHHHHH | 16.72 | 26552605 | |
657 (in isoform 3) | Phosphorylation | - | 11.31 | - | |
666 | Phosphorylation | QQKLNEVYEAVKNYT HHHHHHHHHHHHCCC | 7.62 | 26552605 | |
669 (in isoform 3) | Ubiquitination | - | 2.49 | 21890473 | |
670 | Ubiquitination | NEVYEAVKNYTDKRG HHHHHHHHCCCCCCC | 51.81 | 32015554 | |
671 | Ubiquitination | EVYEAVKNYTDKRGR HHHHHHHCCCCCCCC | 38.03 | 32015554 | |
672 | Phosphorylation | VYEAVKNYTDKRGRR HHHHHHCCCCCCCCE | 15.59 | 26552605 | |
673 | Phosphorylation | YEAVKNYTDKRGRRL HHHHHCCCCCCCCEE | 44.42 | 26552605 | |
681 | O-linked_Glycosylation | DKRGRRLSAIFLRLP CCCCCEEEEEEECCC | 19.94 | 30379171 | |
681 | Phosphorylation | DKRGRRLSAIFLRLP CCCCCEEEEEEECCC | 19.94 | 28450419 | |
681 (in isoform 4) | Phosphorylation | - | 19.94 | 27251275 | |
681 (in isoform 5) | Phosphorylation | - | 19.94 | 24719451 | |
687 | Ubiquitination | LSAIFLRLPSRSELP EEEEEECCCCCCCCC | 4.99 | 32015554 | |
688 | Ubiquitination | SAIFLRLPSRSELPD EEEEECCCCCCCCCC | 22.66 | 32015554 | |
689 | Phosphorylation | AIFLRLPSRSELPDY EEEECCCCCCCCCCE | 53.70 | 28450419 | |
689 (in isoform 4) | Phosphorylation | - | 53.70 | 27251275 | |
689 (in isoform 5) | Phosphorylation | - | 53.70 | - | |
689 (in isoform 6) | Phosphorylation | - | 53.70 | - | |
691 | Phosphorylation | FLRLPSRSELPDYYL EECCCCCCCCCCEEE | 48.07 | 28450419 | |
691 | Ubiquitination | FLRLPSRSELPDYYL EECCCCCCCCCCEEE | 48.07 | 32015554 | |
696 | Phosphorylation | SRSELPDYYLTIKKP CCCCCCCEEEEECCC | 9.83 | 29759185 | |
697 | Phosphorylation | RSELPDYYLTIKKPM CCCCCCEEEEECCCC | 12.54 | 29759185 | |
699 | Phosphorylation | ELPDYYLTIKKPMDM CCCCEEEEECCCCCH | 18.03 | 29449344 | |
701 | Ubiquitination | PDYYLTIKKPMDMEK CCEEEEECCCCCHHH | 45.66 | 21890473 | |
701 (in isoform 1) | Ubiquitination | - | 45.66 | 21890473 | |
701 (in isoform 2) | Ubiquitination | - | 45.66 | 21890473 | |
701 (in isoform 4) | Ubiquitination | - | 45.66 | 21890473 | |
701 (in isoform 5) | Ubiquitination | - | 45.66 | 21890473 | |
701 (in isoform 6) | Ubiquitination | - | 45.66 | 21890473 | |
701 (in isoform 9) | Ubiquitination | - | 45.66 | 21890473 | |
703 | Ubiquitination | YYLTIKKPMDMEKIR EEEEECCCCCHHHHH | 21.00 | 32015554 | |
706 | Ubiquitination | TIKKPMDMEKIRSHM EECCCCCHHHHHHHH | 4.61 | 32015554 | |
708 | Ubiquitination | KKPMDMEKIRSHMMA CCCCCHHHHHHHHHH | 36.46 | 29967540 | |
714 | Ubiquitination | EKIRSHMMANKYQDI HHHHHHHHHHCCCCH | 2.88 | 21890473 | |
716 | Ubiquitination | IRSHMMANKYQDIDS HHHHHHHHCCCCHHH | 26.18 | 21890473 | |
716 (in isoform 7) | Ubiquitination | - | 26.18 | 21890473 | |
716 (in isoform 8) | Ubiquitination | - | 26.18 | 21890473 | |
719 | Ubiquitination | HMMANKYQDIDSMVE HHHHHCCCCHHHHHH | 42.67 | 21890473 | |
722 | Ubiquitination | ANKYQDIDSMVEDFV HHCCCCHHHHHHHHH | 38.68 | 21890473 | |
722 (in isoform 3) | Ubiquitination | - | 38.68 | 21890473 | |
725 | Ubiquitination | YQDIDSMVEDFVMMF CCCHHHHHHHHHHHH | 8.06 | 21890473 | |
731 | Ubiquitination | MVEDFVMMFNNACTY HHHHHHHHHHCCCCC | 2.46 | 21890473 | |
733 | Ubiquitination | EDFVMMFNNACTYNE HHHHHHHHCCCCCCC | 19.79 | 21890473 | |
734 | Ubiquitination | DFVMMFNNACTYNEP HHHHHHHCCCCCCCC | 25.73 | 21890473 | |
737 | Ubiquitination | MMFNNACTYNEPESL HHHHCCCCCCCCHHH | 27.29 | 21890473 | |
743 | Ubiquitination | CTYNEPESLIYKDAL CCCCCCHHHHHHHHH | 30.68 | 21890473 | |
746 | Ubiquitination | NEPESLIYKDALVLH CCCHHHHHHHHHHHH | 14.22 | 21890473 | |
754 | Ubiquitination | KDALVLHKVLLETRR HHHHHHHHHHHHHHH | 30.34 | 21890473 | |
754 (in isoform 1) | Ubiquitination | - | 30.34 | 21890473 | |
754 (in isoform 2) | Ubiquitination | - | 30.34 | 21890473 | |
754 (in isoform 4) | Ubiquitination | - | 30.34 | 21890473 | |
754 (in isoform 5) | Ubiquitination | - | 30.34 | 21890473 | |
754 (in isoform 6) | Ubiquitination | - | 30.34 | 21890473 | |
754 (in isoform 9) | Ubiquitination | - | 30.34 | 21890473 | |
767 | Ubiquitination | RRDLEGDEDSHVPNV HHHHCCCCCCCCCCH | 72.73 | 21890473 | |
769 | Ubiquitination | DLEGDEDSHVPNVTL HHCCCCCCCCCCHHH | 25.08 | 21890473 | |
769 (in isoform 7) | Ubiquitination | - | 25.08 | 21890473 | |
769 (in isoform 8) | Ubiquitination | - | 25.08 | 21890473 | |
772 | Ubiquitination | GDEDSHVPNVTLLIQ CCCCCCCCCHHHHHH | 24.93 | 21890473 | |
775 | Ubiquitination | DSHVPNVTLLIQELI CCCCCCHHHHHHHHH | 23.61 | 21890473 | |
778 | Ubiquitination | VPNVTLLIQELIHNL CCCHHHHHHHHHHHH | 3.17 | 21890473 | |
784 | Ubiquitination | LIQELIHNLFVSVMS HHHHHHHHHHHHHHC | 28.34 | 21890473 | |
786 | Ubiquitination | QELIHNLFVSVMSHQ HHHHHHHHHHHHCCC | 4.71 | 21890473 | |
787 | Ubiquitination | ELIHNLFVSVMSHQD HHHHHHHHHHHCCCC | 4.80 | 21890473 | |
790 | Ubiquitination | HNLFVSVMSHQDDEG HHHHHHHHCCCCCCC | 2.00 | 21890473 | |
796 | Ubiquitination | VMSHQDDEGRCYSDS HHCCCCCCCCCCCCC | 57.75 | 21890473 | |
799 | Ubiquitination | HQDDEGRCYSDSLAE CCCCCCCCCCCCCCC | 5.84 | 21890473 | |
881 | Ubiquitination | KIRDELCKNGEILLS HHHHHHHHCCCEEEC | 79.29 | 29967540 | |
916 (in isoform 3) | Phosphorylation | - | 67.13 | - | |
930 | Ubiquitination | EEKREAEKSEDSSGA HHHHHHHHCCCCCCC | 67.22 | 24816145 | |
931 | Phosphorylation | EKREAEKSEDSSGAA HHHHHHHCCCCCCCC | 37.83 | 30108239 | |
934 | Phosphorylation | EAEKSEDSSGAAGLS HHHHCCCCCCCCCCC | 26.98 | 25159151 | |
934 (in isoform 4) | Phosphorylation | - | 26.98 | 27251275 | |
935 | Phosphorylation | AEKSEDSSGAAGLSG HHHCCCCCCCCCCCC | 44.78 | 28450419 | |
941 | Phosphorylation | SSGAAGLSGLHRTYS CCCCCCCCCCCCCCC | 38.09 | 28450419 | |
943 | Ubiquitination | GAAGLSGLHRTYSQD CCCCCCCCCCCCCCC | 1.91 | 24816145 | |
945 | Ubiquitination | AGLSGLHRTYSQDCS CCCCCCCCCCCCCCC | 40.16 | 24816145 | |
946 | Phosphorylation | GLSGLHRTYSQDCSF CCCCCCCCCCCCCCC | 19.44 | 29691806 | |
947 | Phosphorylation | LSGLHRTYSQDCSFK CCCCCCCCCCCCCCC | 12.32 | 26552605 | |
948 | Phosphorylation | SGLHRTYSQDCSFKN CCCCCCCCCCCCCCC | 20.94 | 23401153 | |
948 | Ubiquitination | SGLHRTYSQDCSFKN CCCCCCCCCCCCCCC | 20.94 | 24816145 | |
948 (in isoform 4) | Phosphorylation | - | 20.94 | 27251275 | |
948 (in isoform 5) | Phosphorylation | - | 20.94 | 24719451 | |
951 | Ubiquitination | HRTYSQDCSFKNSMY CCCCCCCCCCCCCCE | 3.90 | 24816145 | |
952 | Phosphorylation | RTYSQDCSFKNSMYH CCCCCCCCCCCCCEE | 47.77 | 29691806 | |
954 | Acetylation | YSQDCSFKNSMYHVG CCCCCCCCCCCEEEC | 31.64 | 26051181 | |
954 | Ubiquitination | YSQDCSFKNSMYHVG CCCCCCCCCCCEEEC | 31.64 | 24816145 | |
960 | Ubiquitination | FKNSMYHVGDYVYVE CCCCCEEECCEEEEC | 3.26 | 24816145 | |
962 | Ubiquitination | NSMYHVGDYVYVEPA CCCEEECCEEEECCH | 28.74 | 24816145 | |
963 | Ubiquitination | SMYHVGDYVYVEPAE CCEEECCEEEECCHH | 6.43 | 24816145 | |
966 | Ubiquitination | HVGDYVYVEPAEANL EECCEEEECCHHHCC | 5.18 | 24816145 | |
972 | Ubiquitination | YVEPAEANLQPHIVC EECCHHHCCCCEEEE | 30.62 | 24816145 | |
975 | Ubiquitination | PAEANLQPHIVCIER CHHHCCCCEEEEEEE | 23.49 | 24816145 | |
987 | Phosphorylation | IERLWEDSAGEKWLY EEECCCCCCCCEEEE | 27.02 | 28355574 | |
990 | Ubiquitination | LWEDSAGEKWLYGCW CCCCCCCCEEEEEEE | 40.55 | 29967540 | |
994 | Ubiquitination | SAGEKWLYGCWFYRP CCCCEEEEEEEEECC | 14.77 | 29967540 | |
1005 | Ubiquitination | FYRPNETFHLATRKF EECCCCCEEHHHHHH | 3.47 | 27667366 | |
1019 | Acetylation | FLEKEVFKSDYYNKV HHHHHHHCCCCCCCC | 47.82 | 25953088 | |
1019 | Ubiquitination | FLEKEVFKSDYYNKV HHHHHHHCCCCCCCC | 47.82 | 29967540 | |
1025 | Acetylation | FKSDYYNKVPVSKIL HCCCCCCCCCHHHHH | 31.62 | 26051181 | |
1025 | Ubiquitination | FKSDYYNKVPVSKIL HCCCCCCCCCHHHHH | 31.62 | - | |
1026 | Ubiquitination | KSDYYNKVPVSKILG CCCCCCCCCHHHHHH | 5.15 | 27667366 | |
1030 | Ubiquitination | YNKVPVSKILGKCVV CCCCCHHHHHHHHHH | 42.03 | 27667366 | |
1043 | Ubiquitination | VVMFVKEYFKLCPEN HHHHHHHHHHHCCCC | 10.57 | 27667366 | |
1045 | Ubiquitination | MFVKEYFKLCPENFR HHHHHHHHHCCCCCC | 48.56 | 27667366 | |
1048 | Ubiquitination | KEYFKLCPENFRDED HHHHHHCCCCCCCCC | 50.42 | 27667366 | |
1050 | Ubiquitination | YFKLCPENFRDEDVF HHHHCCCCCCCCCEE | 23.54 | 27667366 | |
1051 | Ubiquitination | FKLCPENFRDEDVFV HHHCCCCCCCCCEEE | 11.25 | 27667366 | |
1054 | Ubiquitination | CPENFRDEDVFVCES CCCCCCCCCEEEECC | 52.39 | 27667366 | |
1059 | Ubiquitination | RDEDVFVCESRYSAK CCCCEEEECCCCCCC | 2.39 | 27667366 | |
1060 | Ubiquitination | DEDVFVCESRYSAKT CCCEEEECCCCCCCC | 32.71 | 27667366 | |
1062 | Ubiquitination | DVFVCESRYSAKTKS CEEEECCCCCCCCCC | 13.71 | 27667366 | |
1063 | Ubiquitination | VFVCESRYSAKTKSF EEEECCCCCCCCCCC | 23.43 | 27667366 | |
1065 | Ubiquitination | VCESRYSAKTKSFKK EECCCCCCCCCCCCE | 18.01 | 27667366 | |
1066 | Ubiquitination | CESRYSAKTKSFKKI ECCCCCCCCCCCCEE | 51.01 | 27667366 | |
1069 | Phosphorylation | RYSAKTKSFKKIKLW CCCCCCCCCCEEEEE | 47.75 | - | |
1072 | Ubiquitination | AKTKSFKKIKLWTMP CCCCCCCEEEEEEEE | 42.96 | 27667366 | |
1074 | Ubiquitination | TKSFKKIKLWTMPIS CCCCCEEEEEEEECC | 47.02 | 27667366 | |
1074 (in isoform 4) | Phosphorylation | - | 47.02 | 27251275 | |
1075 | Ubiquitination | KSFKKIKLWTMPISS CCCCEEEEEEEECCC | 5.39 | 27667366 | |
1081 | Phosphorylation | KLWTMPISSVRFVPR EEEEEECCCEEEECC | 19.53 | 24719451 | |
1091 (in isoform 4) | Phosphorylation | - | 34.92 | 27251275 | |
1094 (in isoform 4) | Phosphorylation | - | 5.90 | 27251275 | |
1099 | Phosphorylation | LPVVRVASVFANADK CCEEEEEEECCCCCC | 18.21 | 27251275 | |
1106 | Sumoylation | SVFANADKGDDEKNT EECCCCCCCCCCCCC | 62.93 | 28112733 | |
1111 | Sumoylation | ADKGDDEKNTDNSED CCCCCCCCCCCCCCC | 72.62 | 28112733 | |
1113 | Phosphorylation | KGDDEKNTDNSEDSR CCCCCCCCCCCCCHH | 47.85 | 30108239 | |
1116 | Phosphorylation | DEKNTDNSEDSRAED CCCCCCCCCCHHHHH | 45.66 | 25159151 | |
1119 | Phosphorylation | NTDNSEDSRAEDNFN CCCCCCCHHHHHHCC | 29.37 | 23401153 | |
1136 (in isoform 3) | Phosphorylation | - | 10.95 | - | |
1142 | Ubiquitination | PVEMSNGEPGCHYFE CCCCCCCCCCCCCHH | 42.65 | 29967540 | |
1143 (in isoform 4) | Phosphorylation | - | 52.70 | - | |
1156 | Ubiquitination | EQLHYNDMWLKVGDC HHCCCCCEEEEECCE | 3.93 | 29967540 | |
1167 | Acetylation | VGDCVFIKSHGLVRP ECCEEEEECCCCCCC | 25.57 | 25953088 | |
1167 | Sumoylation | VGDCVFIKSHGLVRP ECCEEEEECCCCCCC | 25.57 | 28112733 | |
1167 | Ubiquitination | VGDCVFIKSHGLVRP ECCEEEEECCCCCCC | 25.57 | 29967540 | |
1168 | Phosphorylation | GDCVFIKSHGLVRPR CCEEEEECCCCCCCC | 20.26 | 20068231 | |
1168 (in isoform 5) | Phosphorylation | - | 20.26 | - | |
1181 | Ubiquitination | PRVGRIEKVWVRDGA CCCCCEEEEEEECCC | 38.74 | 29967540 | |
1188 | Ubiquitination | KVWVRDGAAYFYGPI EEEEECCCEEEECCE | 11.86 | 29967540 | |
1213 | Ubiquitination | PTKMFYKKEVFLSNL CCCCCCCHHHHHHCH | 47.97 | 29967540 | |
1237 | Phosphorylation | LGKCAVLSFKDFLSC HCCEEEEEHHHHHCC | 24.53 | 24719451 | |
1253 (in isoform 4) | Phosphorylation | - | 31.11 | 27251275 | |
1261 | Phosphorylation | ILLCESRYNESDKQM EEEECCCCCCCHHHH | 32.34 | 25367160 | |
1268 | Neddylation | YNESDKQMKKFKGLK CCCCHHHHHHCCCCC | 6.67 | 32015554 | |
1268 | Ubiquitination | YNESDKQMKKFKGLK CCCCHHHHHHCCCCC | 6.67 | 29967540 | |
1274 | Ubiquitination | QMKKFKGLKRFSLSA HHHHCCCCCCEECEE | 3.57 | 29967540 | |
1278 | Phosphorylation | FKGLKRFSLSAKVVD CCCCCCEECEEEEEC | 26.00 | 30108239 | |
1278 (in isoform 5) | Phosphorylation | - | 26.00 | 24719451 | |
1280 | Phosphorylation | GLKRFSLSAKVVDDE CCCCEECEEEEECCE | 25.50 | 30108239 | |
1282 | Ubiquitination | KRFSLSAKVVDDEIY CCEECEEEEECCEEE | 39.14 | 29967540 | |
1283 | Ubiquitination | RFSLSAKVVDDEIYY CEECEEEEECCEEEE | 5.96 | 29967540 | |
1289 | Neddylation | KVVDDEIYYFRKPIV EEECCEEEEECCCCC | 8.43 | 32015554 | |
1289 | Phosphorylation | KVVDDEIYYFRKPIV EEECCEEEEECCCCC | 8.43 | 22817900 | |
1293 | Sumoylation | DEIYYFRKPIVPQKE CEEEEECCCCCCCCC | 29.24 | - | |
1293 | Acetylation | DEIYYFRKPIVPQKE CEEEEECCCCCCCCC | 29.24 | 26051181 | |
1293 | Neddylation | DEIYYFRKPIVPQKE CEEEEECCCCCCCCC | 29.24 | 32015554 | |
1293 | Sumoylation | DEIYYFRKPIVPQKE CEEEEECCCCCCCCC | 29.24 | 25114211 | |
1293 | Ubiquitination | DEIYYFRKPIVPQKE CEEEEECCCCCCCCC | 29.24 | 29967540 | |
1294 | Neddylation | EIYYFRKPIVPQKEP EEEEECCCCCCCCCC | 28.66 | 32015554 | |
1299 | Ubiquitination | RKPIVPQKEPSPLLE CCCCCCCCCCCCHHH | 66.57 | 29967540 | |
1302 | Phosphorylation | IVPQKEPSPLLEKKI CCCCCCCCCHHHHHH | 29.31 | 28555341 | |
1304 | Neddylation | PQKEPSPLLEKKIQL CCCCCCCHHHHHHHH | 13.00 | 32015554 | |
1307 | Ubiquitination | EPSPLLEKKIQLLEA CCCCHHHHHHHHHHH | 55.96 | 29967540 | |
1308 | Sumoylation | PSPLLEKKIQLLEAK CCCHHHHHHHHHHHH | 26.72 | 28112733 | |
1308 | Ubiquitination | PSPLLEKKIQLLEAK CCCHHHHHHHHHHHH | 26.72 | 29967540 | |
1310 | Neddylation | PLLEKKIQLLEAKFA CHHHHHHHHHHHHHH | 49.20 | 32015554 | |
1311 | Neddylation | LLEKKIQLLEAKFAE HHHHHHHHHHHHHHH | 5.48 | 32015554 | |
1314 | Neddylation | KKIQLLEAKFAELEG HHHHHHHHHHHHHCC | 16.55 | 32015554 | |
1326 | Neddylation | LEGGDDDIEEMGEED HCCCCCCHHHCCCCC | 6.59 | 32015554 | |
1328 | Neddylation | GGDDDIEEMGEEDSE CCCCCHHHCCCCCCC | 53.47 | 32015554 | |
1329 | Neddylation | GDDDIEEMGEEDSEV CCCCHHHCCCCCCCC | 5.48 | 32015554 | |
1346 | Ubiquitination | PPSLPQLQTPLASEL CCCCCCCCCCCCCCC | 35.51 | 21890473 | |
1346 (in isoform 4) | Ubiquitination | - | 35.51 | 21890473 | |
1353 (in isoform 4) | Phosphorylation | - | 5.93 | 27251275 | |
1359 | Phosphorylation | ELDLMPYTPPQSTPK CCCCCCCCCCCCCCC | 23.71 | 24275569 | |
1363 | Phosphorylation | MPYTPPQSTPKSAKG CCCCCCCCCCCCCCC | 53.07 | 24275569 | |
1366 (in isoform 3) | Ubiquitination | - | 64.23 | 21890473 | |
1367 | Phosphorylation | PPQSTPKSAKGSAKK CCCCCCCCCCCCCCC | 36.09 | - | |
1371 | Phosphorylation | TPKSAKGSAKKEGSK CCCCCCCCCCCCCCC | 35.89 | - | |
1373 (in isoform 3) | Phosphorylation | - | 53.72 | - | |
1373 (in isoform 9) | Ubiquitination | - | 53.72 | 21890473 | |
1384 | Phosphorylation | SKRKINMSGYILFSS CCCCCCCCEEEEEEH | 24.77 | 28555341 | |
1386 | Phosphorylation | RKINMSGYILFSSEM CCCCCCEEEEEEHHH | 6.27 | 29449344 | |
1390 | Phosphorylation | MSGYILFSSEMRAVI CCEEEEEEHHHHHHH | 23.19 | 29116813 | |
1391 | Phosphorylation | SGYILFSSEMRAVIK CEEEEEEHHHHHHHH | 28.25 | 29116813 | |
1394 | Ubiquitination | ILFSSEMRAVIKAQH EEEEHHHHHHHHHHC | 22.96 | 21890473 | |
1398 | Sumoylation | SEMRAVIKAQHPDYS HHHHHHHHHHCCCCC | 35.08 | - | |
1398 | Sumoylation | SEMRAVIKAQHPDYS HHHHHHHHHHCCCCC | 35.08 | 28112733 | |
1398 | Ubiquitination | SEMRAVIKAQHPDYS HHHHHHHHHHCCCCC | 35.08 | 23000965 | |
1398 (in isoform 1) | Ubiquitination | - | 35.08 | 21890473 | |
1398 (in isoform 2) | Ubiquitination | - | 35.08 | 21890473 | |
1398 (in isoform 5) | Ubiquitination | - | 35.08 | 21890473 | |
1404 | Phosphorylation | IKAQHPDYSFGELSR HHHHCCCCCHHHHHH | 15.45 | 21712546 | |
1405 | Phosphorylation | KAQHPDYSFGELSRL HHHCCCCCHHHHHHH | 33.87 | 23401153 | |
1405 (in isoform 5) | Phosphorylation | - | 33.87 | 24719451 | |
1410 | Phosphorylation | DYSFGELSRLVGTEW CCCHHHHHHHHCCCC | 21.18 | 25159151 | |
1411 | Ubiquitination | YSFGELSRLVGTEWR CCHHHHHHHHCCCCC | 46.12 | 21890473 | |
1413 | Ubiquitination | FGELSRLVGTEWRNL HHHHHHHHCCCCCCH | 9.66 | 21890473 | |
1413 (in isoform 7) | Ubiquitination | - | 9.66 | 21890473 | |
1413 (in isoform 8) | Ubiquitination | - | 9.66 | 21890473 | |
1416 | Ubiquitination | LSRLVGTEWRNLETA HHHHHCCCCCCHHHH | 38.21 | 21890473 | |
1418 | Ubiquitination | RLVGTEWRNLETAKK HHHCCCCCCHHHHHH | 31.46 | 21890473 | |
1419 | Ubiquitination | LVGTEWRNLETAKKA HHCCCCCCHHHHHHH | 43.21 | 21890473 | |
1422 | Phosphorylation | TEWRNLETAKKAEYE CCCCCHHHHHHHHHH | 47.12 | 21712546 | |
1422 | Ubiquitination | TEWRNLETAKKAEYE CCCCCHHHHHHHHHH | 47.12 | 21890473 | |
1427 | Ubiquitination | LETAKKAEYEERAAK HHHHHHHHHHHHHHH | 63.46 | 21890473 | |
1428 | Ubiquitination | ETAKKAEYEERAAKV HHHHHHHHHHHHHHH | 28.13 | 21890473 | |
1430 | Ubiquitination | AKKAEYEERAAKVAE HHHHHHHHHHHHHHH | 46.87 | 21890473 | |
1431 | Ubiquitination | KKAEYEERAAKVAEQ HHHHHHHHHHHHHHH | 28.09 | 21890473 | |
1433 | Ubiquitination | AEYEERAAKVAEQQE HHHHHHHHHHHHHHH | 17.05 | 21890473 | |
1434 | Ubiquitination | EYEERAAKVAEQQER HHHHHHHHHHHHHHH | 40.78 | 21890473 | |
1440 | Ubiquitination | AKVAEQQERERAAQQ HHHHHHHHHHHHHHH | 57.09 | 21890473 | |
1442 | Ubiquitination | VAEQQERERAAQQQQ HHHHHHHHHHHHHHC | 46.01 | 21890473 | |
1443 | Ubiquitination | AEQQERERAAQQQQP HHHHHHHHHHHHHCC | 41.25 | 21890473 | |
1451 | Phosphorylation | AAQQQQPSASPRAGT HHHHHCCCCCCCCCC | 36.72 | 29255136 | |
1453 | Phosphorylation | QQQQPSASPRAGTPV HHHCCCCCCCCCCCC | 21.18 | 29255136 | |
1505 | Ubiquitination | QGPVDGLVSMGSMQP CCCCCCCEECCCCCC | 4.53 | 29967540 | |
1519 | Ubiquitination | PLHPGGPPPHHLPPG CCCCCCCCCCCCCCC | 44.10 | 29967540 | |
1531 | Ubiquitination | PPGVPGLPGIPPPGV CCCCCCCCCCCCCCC | 44.58 | 33845483 | |
1535 | Ubiquitination | PGLPGIPPPGVMNQG CCCCCCCCCCCCCCC | 36.03 | 33845483 | |
1535 (in isoform 4) | Ubiquitination | - | 36.03 | 21890473 | |
1535 (in isoform 5) | Ubiquitination | - | 36.03 | 21890473 | |
1536 | Ubiquitination | GLPGIPPPGVMNQGV CCCCCCCCCCCCCCC | 42.53 | 33845483 | |
1546 | Ubiquitination | MNQGVAPMVGTPAPG CCCCCCCCCCCCCCC | 2.90 | 33845483 | |
1547 | Ubiquitination | NQGVAPMVGTPAPGG CCCCCCCCCCCCCCC | 8.22 | 29967540 | |
1550 (in isoform 7) | Ubiquitination | - | 30.45 | 21890473 | |
1552 | Ubiquitination | PMVGTPAPGGSPYGQ CCCCCCCCCCCCCCC | 49.21 | 33845483 | |
1553 | Ubiquitination | MVGTPAPGGSPYGQQ CCCCCCCCCCCCCCC | 51.85 | 33845483 | |
1555 (in isoform 3) | Ubiquitination | - | 22.36 | 21890473 | |
1556 | Ubiquitination | TPAPGGSPYGQQVGV CCCCCCCCCCCCCCC | 40.31 | 33845483 | |
1562 (in isoform 9) | Ubiquitination | - | 12.47 | 21890473 | |
1568 | Ubiquitination | VGVLGPPGQQAPPPY CCCCCCCCCCCCCCC | 35.05 | 33845483 | |
1570 | Ubiquitination | VLGPPGQQAPPPYPG CCCCCCCCCCCCCCC | 62.85 | 33845483 | |
1571 | Ubiquitination | LGPPGQQAPPPYPGP CCCCCCCCCCCCCCC | 15.64 | 33845483 | |
1587 | Ubiquitination | PAGPPVIQQPTTPMF CCCCCCCCCCCCCCC | 43.35 | 33845483 | |
1587 (in isoform 2) | Ubiquitination | - | 43.35 | 21890473 | |
1605 (in isoform 8) | Ubiquitination | - | 4.56 | 21890473 | |
1611 | Ubiquitination | LLHSEAYLKYIEGLS HHCCHHHHHHHHHCC | 4.35 | 33845483 | |
1612 | Ubiquitination | LHSEAYLKYIEGLSA HCCHHHHHHHHHCCC | 31.35 | - | |
1618 | Phosphorylation | LKYIEGLSAESNSIS HHHHHHCCCCCCCCC | 40.63 | 26074081 | |
1621 | Phosphorylation | IEGLSAESNSISKWD HHHCCCCCCCCCHHH | 35.28 | 26074081 | |
1623 | Phosphorylation | GLSAESNSISKWDQT HCCCCCCCCCHHHHH | 37.20 | 26074081 | |
1625 | Phosphorylation | SAESNSISKWDQTLA CCCCCCCCHHHHHHH | 27.75 | 26074081 | |
1626 | Acetylation | AESNSISKWDQTLAA CCCCCCCHHHHHHHH | 53.79 | 26051181 | |
1626 | Ubiquitination | AESNSISKWDQTLAA CCCCCCCHHHHHHHH | 53.79 | - | |
1630 | Phosphorylation | SISKWDQTLAARRRD CCCHHHHHHHHHHHH | 18.85 | 26074081 | |
1641 | Phosphorylation | RRRDVHLSKEQESRL HHHHHCCCHHHHHCC | 21.19 | 26074081 | |
1642 | Sumoylation | RRDVHLSKEQESRLP HHHHCCCHHHHHCCC | 70.54 | 28112733 | |
1642 | Ubiquitination | RRDVHLSKEQESRLP HHHHCCCHHHHHCCC | 70.54 | 2190698 | |
1642 (in isoform 1) | Ubiquitination | - | 70.54 | 21890473 | |
1654 | Methylation | RLPSHWLKSKGAHTT CCCHHHHHHCCCCCH | 44.95 | 115975379 | |
1654 | Sumoylation | RLPSHWLKSKGAHTT CCCHHHHHHCCCCCH | 44.95 | 28112733 | |
1654 | Ubiquitination | RLPSHWLKSKGAHTT CCCHHHHHHCCCCCH | 44.95 | - | |
1656 | Sumoylation | PSHWLKSKGAHTTMA CHHHHHHCCCCCHHH | 59.54 | 28112733 | |
1656 | Ubiquitination | PSHWLKSKGAHTTMA CHHHHHHCCCCCHHH | 59.54 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
948 | S | Phosphorylation | Kinase | ATM | Q13315 | PSP |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PB1_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PB1_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
H31_HUMAN | HIST1H3A | physical | 20368734 | |
H2B2E_HUMAN | HIST2H2BE | physical | 20368734 | |
H2A2C_HUMAN | HIST2H2AC | physical | 20368734 | |
TAT_HV1H2 | tat | physical | 20368734 | |
CHD7_HUMAN | CHD7 | physical | 20130577 | |
ARID2_HUMAN | ARID2 | physical | 15985610 | |
SMRC2_HUMAN | SMARCC2 | physical | 15985610 | |
SMRC1_HUMAN | SMARCC1 | physical | 15985610 | |
SMRD1_HUMAN | SMARCD1 | physical | 15985610 | |
SMCE1_HUMAN | SMARCE1 | physical | 15985610 | |
ACL6A_HUMAN | ACTL6A | physical | 15985610 | |
SNF5_HUMAN | SMARCB1 | physical | 15985610 | |
SMCA4_HUMAN | SMARCA4 | physical | 15985610 | |
H31T_HUMAN | HIST3H3 | physical | 17320048 | |
CALL5_HUMAN | CALML5 | physical | 16934469 | |
A4_HUMAN | APP | physical | 21832049 | |
TF3C5_HUMAN | GTF3C5 | physical | 22939629 | |
TCHL1_HUMAN | TCHHL1 | physical | 22939629 | |
ARID2_HUMAN | ARID2 | physical | 26344197 | |
CSN3_HUMAN | COPS3 | physical | 26344197 | |
TOP1_HUMAN | TOP1 | genetic | 28319113 | |
VHL_HUMAN | VHL | genetic | 28319113 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
144700 | Renal cell carcinoma (RCC) | |||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10, AND MASSSPECTROMETRY. | |
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-948, AND MASSSPECTROMETRY. | |
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-636 AND SER-1453, ANDMASS SPECTROMETRY. | |
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-39, AND MASSSPECTROMETRY. | |
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10; SER-39; SER-353;SER-355; SER-371; SER-375; SER-498 AND SER-636, AND MASS SPECTROMETRY. | |
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-178; SER-636 ANDSER-1453, AND MASS SPECTROMETRY. | |
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-39; SER-131; SER-314;SER-316; SER-319; SER-353; SER-355; SER-636 AND SER-1405, AND MASSSPECTROMETRY. | |
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-636, AND MASSSPECTROMETRY. | |
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-301, AND MASSSPECTROMETRY. | |
"Quantitative phosphoproteome analysis using a dendrimer conjugationchemistry and tandem mass spectrometry."; Tao W.A., Wollscheid B., O'Brien R., Eng J.K., Li X.-J.,Bodenmiller B., Watts J.D., Hood L., Aebersold R.; Nat. Methods 2:591-598(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-54, AND MASSSPECTROMETRY. |