SETD9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SETD9_HUMAN
• UniProt AC: Q8NE22
• Protein Name: SET domain-containing protein 9
• Gene Name: SETD9
• Organism: Homo sapiens (Human).
• Sequence Length: 299
• Protein Sequence: MPGRLLRGLWQRWRRYKYRFVPWIALNLSHNPRTLRYVPEESKDKVISDEDVLGTLLKVFQALFLNDFNKQSEILSMLPESVKSKYQDLLAVEHQGVKLLENRHQQQSTFKPEEILYKTLGFSVAQATSSLISAGKGVFVTKGLVPKGAVVSMYPGTVYQKYEPIFFQSIGNPFIFRCLDGVLIDGNDKGISKVVYRSCNGRDRLGPLKMSDSTWLTSEIHNPLAVGQYVNNCSNDRAANVCYQEFDVPAVFPIELKQYLPNIAYSYDKQSPLRCVVLVALRDINQGEELFSNYYTIVS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
81	Phosphorylation	ILSMLPESVKSKYQD HHHCCCHHHHHHHHH	32.67	-
111	Acetylation	HQQQSTFKPEEILYK HHCCCCCCHHHHHHH	52.16	25038526
157	Phosphorylation	VVSMYPGTVYQKYEP EEEECCCCCEEEEEE	16.13	20067319
292	Phosphorylation	NQGEELFSNYYTIVS CCCCCHHHCCEEEEC	36.22	23663014
294	Phosphorylation	GEELFSNYYTIVS-- CCCHHHCCEEEEC--	10.78	23663014
295	Phosphorylation	EELFSNYYTIVS--- CCHHHCCEEEEC---	8.34	23663014
296	Phosphorylation	ELFSNYYTIVS---- CHHHCCEEEEC----	12.44	23663014
299	Phosphorylation	SNYYTIVS------- HCCEEEEC-------	30.56	23663014

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SETD9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SETD9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SETD9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
USO1_HUMAN	USO1	physical	26186194
USO1_HUMAN	USO1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.