T4S19_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T4S19_HUMAN
• UniProt AC: Q96DZ7
• Protein Name: Transmembrane 4 L6 family member 19
• Gene Name: TM4SF19
• Organism: Homo sapiens (Human).
• Sequence Length: 209
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MVSSPCTQASSRTCSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALKDGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCISLLQLLLVVVHVINSLLGLFCSLCEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MVSSPCTQAS -----CCCCCCCHHH	27.54	18691976
4	Phosphorylation	----MVSSPCTQASS ----CCCCCCCHHHH	16.75	29083192
7	Phosphorylation	-MVSSPCTQASSRTC -CCCCCCCHHHHCHH	30.47	29083192
10	Phosphorylation	SSPCTQASSRTCSRI CCCCCHHHHCHHHHH	15.55	29083192
11	Phosphorylation	SPCTQASSRTCSRIL CCCCHHHHCHHHHHH	34.33	29083192
133	N-linked_Glycosylation	MFDVSSFNQTQAWKY EEECCCCCCHHHHHC	46.03	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T4S19_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T4S19_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T4S19_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of T4S19_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-3, AND MASSSPECTROMETRY.
PubMed: 18691976