TMG2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMG2_HUMAN
• UniProt AC: O14669
• Protein Name: Transmembrane gamma-carboxyglutamic acid protein 2
• Gene Name: PRRG2
• Organism: Homo sapiens (Human).
• Sequence Length: 202
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Sequence: MRGHPSLLLLYMALTTCLDTSPSEETDQEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTGGILLIVLAGLGAFWYLRWRQHRGQQPCPQEAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYTSLRRPH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Gamma-carboxyglutamic_acid	LERECLEERCSWEEA HHHHHHHHHCCHHHH	46.14	-
109	Phosphorylation	RGRVDVASLAVGLTG CCCCCHHHHHHHHHH	19.40	-
115	Phosphorylation	ASLAVGLTGGILLIV HHHHHHHHHHHHHHH	27.68	-
131	Phosphorylation	AGLGAFWYLRWRQHR HHCHHHHHHHHHHHC	4.67	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMG2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMG2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMG2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FATE1_HUMAN	FATE1	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.