RAB2B_HUMAN - dbPTM
RAB2B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RAB2B_HUMAN
UniProt AC Q8WUD1
Protein Name Ras-related protein Rab-2B
Gene Name RAB2B
Organism Homo sapiens (Human).
Sequence Length 216
Subcellular Localization Cell membrane
Lipid-anchor
Cytoplasmic side . Endoplasmic reticulum membrane . Golgi apparatus membrane .
Protein Description Required for protein transport from the endoplasmic reticulum to the Golgi complex..
Protein Sequence MTYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPSASQRNSRDIGSNSGCC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTYAYLFKY
------CCCEEEEEE		19.5028442448
3Phosphorylation-----MTYAYLFKYI
-----CCCEEEEEEE		7.6125884760
5Phosphorylation---MTYAYLFKYIII
---CCCEEEEEEEEE		11.4028152594
9PhosphorylationTYAYLFKYIIIGDTG
CCEEEEEEEEECCCC		7.0421945579
15PhosphorylationKYIIIGDTGVGKSCL
EEEEECCCCCCHHHE		28.6721945579
20PhosphorylationGDTGVGKSCLLLQFT
CCCCCCHHHEEEEEE		12.2220068231
27PhosphorylationSCLLLQFTDKRFQPV
HHEEEEEECCCCCCC		27.8720068231
56UbiquitinationNIDGKQIKLQIWDTA
EECCEEEEEEEEECC		31.6721906983
62PhosphorylationIKLQIWDTAGQESFR
EEEEEEECCCHHHHH		20.0728450419
67PhosphorylationWDTAGQESFRSITRS
EECCCHHHHHHHHHH		20.3325693802
70PhosphorylationAGQESFRSITRSYYR
CCHHHHHHHHHHHHC		26.7128450419
72PhosphorylationQESFRSITRSYYRGA
HHHHHHHHHHHHCCC		18.1428450419
86PhosphorylationAAGALLVYDITRRET
CCEEEEEEECCHHHH		11.12-
89PhosphorylationALLVYDITRRETFNH
EEEEEECCHHHHHHH		22.30-
121PhosphorylationIMLIGNKSDLESRRD
EEEECCHHHHHHHHH		51.9726437602
125PhosphorylationGNKSDLESRRDVKRE
CCHHHHHHHHHHHHH		39.6526437602
165UbiquitinationEAFINTAKEIYRKIQ
HHHHHHHHHHHHHHH		42.48-
192PhosphorylationIKIGPQQSISTSVGP
EEECCCCEECCCCCC		17.1725307156
194PhosphorylationIGPQQSISTSVGPSA
ECCCCEECCCCCCCH		21.6328857561
195PhosphorylationGPQQSISTSVGPSAS
CCCCEECCCCCCCHH		26.2627732954
196PhosphorylationPQQSISTSVGPSASQ
CCCEECCCCCCCHHH		20.4927732954
200PhosphorylationISTSVGPSASQRNSR
ECCCCCCCHHHCCCC		34.3227732954
202PhosphorylationTSVGPSASQRNSRDI
CCCCCCHHHCCCCCC		33.7317525332
206PhosphorylationPSASQRNSRDIGSNS
CCHHHCCCCCCCCCC		33.2525693802
215GeranylgeranylationDIGSNSGCC------
CCCCCCCCC------		2.21-
216GeranylgeranylationIGSNSGCC-------
CCCCCCCC-------		7.73-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RAB2B_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RAB2B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RAB2B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
NXP20_HUMANFAM114A1physical
25416956
FA71C_HUMANFAM71Cphysical
25416956
RAB2A_HUMANRAB2Aphysical
28514442
GDIA_HUMANGDI1physical
28514442
RAB5B_HUMANRAB5Bphysical
28514442
RAB14_HUMANRAB14physical
28514442
PRUN1_HUMANPRUNEphysical
28514442
RAB4A_HUMANRAB4Aphysical
28514442
RAB9A_HUMANRAB9Aphysical
28514442
TTF2_HUMANTTF2physical
28514442
FMN2_HUMANFMN2physical
28514442
DUSTY_HUMANDSTYKphysical
28514442
RAB21_HUMANRAB21physical
28514442
RAB5A_HUMANRAB5Aphysical
28514442
REXO5_HUMANLOC81691physical
28514442
RAB1B_HUMANRAB1Bphysical
28514442
UBA6_HUMANUBA6physical
28514442
DD19B_HUMANDDX19Bphysical
28514442
DMWD_HUMANDMWDphysical
28514442
RAB18_HUMANRAB18physical
28514442
RAB1A_HUMANRAB1Aphysical
28514442
AT12A_HUMANATP12Aphysical
28514442
TBCD4_HUMANTBC1D4physical
28514442
BCAS3_HUMANBCAS3physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RAB2B_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory