| UniProt ID | AIPL1_HUMAN | |
|---|---|---|
| UniProt AC | Q9NZN9 | |
| Protein Name | Aryl-hydrocarbon-interacting protein-like 1 | |
| Gene Name | AIPL1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 384 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | May be important in protein trafficking and/or protein folding and stabilization.. | |
| Protein Sequence | MDAALLLNVEGVKKTILHGGTGELPNFITGSRVIFHFRTMKCDEERTVIDDSRQVGQPMHIIIGNMFKLEVWEILLTSMRVHEVAEFWCDTIHTGVYPILSRSLRQMAQGKDPTEWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLVFVIELLQVDAPSDYQRETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLRNLQTKEKPWEVQWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPTEPPAQSSTEPPAEPPTAPSAELSAGPPAEPATEPPPSPGHSLQH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 34 (in isoform 2) | Phosphorylation | - | 1.84 | 22210691 | |
| 47 | Phosphorylation | MKCDEERTVIDDSRQ EECCCCCEEECCCCC | 25.70 | 22468782 | |
| 52 | Phosphorylation | ERTVIDDSRQVGQPM CCEEECCCCCCCCCE | 22.36 | 22468782 | |
| 101 | Phosphorylation | TGVYPILSRSLRQMA HCHHHHHHHHHHHHH | 22.12 | 23927012 | |
| 103 | Phosphorylation | VYPILSRSLRQMAQG HHHHHHHHHHHHHCC | 25.24 | 25954137 | |
| 214 | Ubiquitination | CLRNLQTKEKPWEVQ HHHCCCCCCCCCHHH | 51.27 | - | |
| 247 | Phosphorylation | LLKKEEYYEVLEHTS HHCHHHHHHHHHHHH | 11.66 | 22817900 | |
| 267 | Phosphorylation | HPGIVKAYYVRARAH CCCHHEEEEHHHHHH | 9.22 | 22817900 | |
| 268 | Phosphorylation | PGIVKAYYVRARAHA CCHHEEEEHHHHHHH | 6.58 | 22817900 | |
| 275 | Methylation | YVRARAHAEVWNEAE EHHHHHHHHHHCHHH | 16.44 | - | |
| 299 | Trimethylation | ELEPSMQKAVRRELR HCCHHHHHHHHHHHH | 39.96 | - | |
| 299 | Methylation | ELEPSMQKAVRRELR HCCHHHHHHHHHHHH | 39.96 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of AIPL1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of AIPL1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of AIPL1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NUB1_HUMAN | NUB1 | physical | 12374762 | |
| NUB1_HUMAN | NUB1 | physical | 22347407 | |
| UBD_HUMAN | UBD | physical | 22347407 | |
| UBA6_HUMAN | UBA6 | physical | 22347407 | |
| NUB1_HUMAN | NUB1 | physical | 15081406 | |
| HS90A_BOVIN | HSP90AA1 | physical | 18408180 | |
| HS90B_BOVIN | HSP90AB1 | physical | 18408180 | |
| HSP7C_BOVIN | HSPA8 | physical | 18408180 | |
| HSP74_HUMAN | HSPA4 | physical | 18408180 | |
| HSP7C_HUMAN | HSPA8 | physical | 18408180 | |
| HS90A_HUMAN | HSP90AA1 | physical | 18408180 | |
| NUB1_HUMAN | NUB1 | physical | 15180275 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 604393 | Leber congenital amaurosis 4 (LCA4) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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