RAMP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RAMP1_HUMAN
• UniProt AC: O60894
• Protein Name: Receptor activity-modifying protein 1
• Gene Name: RAMP1
• Organism: Homo sapiens (Human).
• Sequence Length: 148
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Description: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL..
• Protein Sequence: MARALCRLPRRGLWLLLAHHLFMTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYRELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPITVTLLVTALVVWQSKRTEGIV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
100	Phosphorylation	FLAVHGRYFRSCPIS EEHHHCCEEECCCCC	14.13	28509920
103	Phosphorylation	VHGRYFRSCPISGRA HHCCEEECCCCCCCC	17.85	-
107	Phosphorylation	YFRSCPISGRAVRDP EEECCCCCCCCCCCC	13.84	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RAMP1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RAMP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RAMP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CALRL_HUMAN	CALCRL	physical	11535606
RAMP1_HUMAN	RAMP1	physical	11535606
RAMP1_HUMAN	RAMP1	physical	9620797
CALRL_HUMAN	CALCRL	physical	12684503

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.