GGN_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GGN_HUMAN
• UniProt AC: Q86UU5
• Protein Name: Gametogenetin
• Gene Name: GGN
• Organism: Homo sapiens (Human).
• Sequence Length: 652
• Protein Description: May be involved in spermatogenesis..
• Protein Sequence: MGNLQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEMAQPADSESGLSLLCKITFKSRPSLAPPAASSSLAAKASLGGGGGGGLFAASGAISYAEVLKQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGPPSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAARGATRKDGLHGDGPRERATATVPDSSGGGGGGSGASQTGAANTRAARHWLPFQVLNSCPCKCYCHHQPRHRRLPRNVSAWLSTSTNHLGEPPWVATIKLSGSLVAKLEHYDLQATHSN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	APDSRRTSLVEPEMT CCCCCCCCCCCHHHH	28.71	24719451
38	Phosphorylation	LVEPEMTSQAMRLTR CCCHHHHHHHHHHHC	18.03	-
69	Phosphorylation	VPREPQASPSTLPLT CCCCCCCCCCCCCCE	17.71	28122231
71	Phosphorylation	REPQASPSTLPLTLE CCCCCCCCCCCCEEC	39.83	28122231
72	Phosphorylation	EPQASPSTLPLTLER CCCCCCCCCCCEECC	35.46	28122231
129	Phosphorylation	IRRLLEASHRGQGDP HHHHHHHHHCCCCCC	12.35	24719451
138	Phosphorylation	RGQGDPPSLRPLKPP CCCCCCCCCCCCCCC	42.26	24719451
156	Phosphorylation	RQLSVKDTVPRAPSQ CCCCCCCCCCCCCCC	27.05	24905233
179	Phosphorylation	KPPPPLPSERQPADR CCCCCCCCCCCCCCC	53.76	24719451
212	Phosphorylation	GPRNQGQTAGRARGG CCCCCCCCCCCCCCC	37.59	23286773
252	Phosphorylation	ITFKSRPSLAPPAAS EEECCCCCCCCCCCC	35.73	22617229
259	Phosphorylation	SLAPPAASSSLAAKA CCCCCCCCCHHHHHH	23.67	22617229
260	Phosphorylation	LAPPAASSSLAAKAS CCCCCCCCHHHHHHH	25.33	22617229
389	Phosphorylation	ALSGPWGSPPPPPEQ HHCCCCCCCCCCHHH	30.30	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GGN_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GGN_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GGN_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GGN_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.