NMI_HUMAN - dbPTM
NMI_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NMI_HUMAN
UniProt AC Q13287
Protein Name N-myc-interactor
Gene Name NMI
Organism Homo sapiens (Human).
Sequence Length 307
Subcellular Localization Cytoplasm.
Protein Description May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5..
Protein Sequence MEADKDDTQQILKEHSPDEFIKDEQNKGLIDEITKKNIQLKKEIQKLETELQEATKEFQIKEDIPETKMKFLSVETPENDSQLSNISCSFQVSSKVPYEIQKGQALITFEKEEVAQNVVSMSKHHVQIKDVNLEVTAKPVPLNSGVRFQVYVEVSKMKINVTEIPDTLREDQMRDKLELSFSKSRNGGGEVDRVDYDRQSGSAVITFVEIGVADKILKKKEYPLYINQTCHRVTVSPYTEIHLKKYQIFSGTSKRTVLLTGMEGIQMDEEIVEDLINIHFQRAKNGGGEVDVVKCSLGQPHIAYFEE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
16PhosphorylationQQILKEHSPDEFIKD
HHHHHHHCHHHHCCH		34.8329255136
27UbiquitinationFIKDEQNKGLIDEIT
HCCHHHCCCHHHHHH		55.5829967540
35UbiquitinationGLIDEITKKNIQLKK
CHHHHHHHHHHHHHH		49.8629967540
36UbiquitinationLIDEITKKNIQLKKE
HHHHHHHHHHHHHHH		51.11-
46UbiquitinationQLKKEIQKLETELQE
HHHHHHHHHHHHHHH		54.6929967540
56UbiquitinationTELQEATKEFQIKED
HHHHHHHHHCCCCCC		64.6829967540
61UbiquitinationATKEFQIKEDIPETK
HHHHCCCCCCCCCCC		38.2529967540
67O-linked_GlycosylationIKEDIPETKMKFLSV
CCCCCCCCCCEEEEE		30.9630379171
68UbiquitinationKEDIPETKMKFLSVE
CCCCCCCCCEEEEEE		38.13-
70UbiquitinationDIPETKMKFLSVETP
CCCCCCCEEEEEECC		44.7129967540
73PhosphorylationETKMKFLSVETPEND
CCCCEEEEEECCCCC		22.50-
95UbiquitinationCSFQVSSKVPYEIQK
EEEEECCCCCEEEEC		39.4629967540
98PhosphorylationQVSSKVPYEIQKGQA
EECCCCCEEEECCCE		28.75-
102UbiquitinationKVPYEIQKGQALITF
CCCEEEECCCEEEEE		59.6629967540
111UbiquitinationQALITFEKEEVAQNV
CEEEEECHHHHHHHH		55.7929967540
123UbiquitinationQNVVSMSKHHVQIKD
HHHHHHCCCCEEEEE		29.14-
129UbiquitinationSKHHVQIKDVNLEVT
CCCCEEEEECEEEEE		38.23-
136PhosphorylationKDVNLEVTAKPVPLN
EECEEEEEEEEEECC		21.4220068231
138UbiquitinationVNLEVTAKPVPLNSG
CEEEEEEEEEECCCC		36.86-
144PhosphorylationAKPVPLNSGVRFQVY
EEEEECCCCCEEEEE		46.4720068231
158UbiquitinationYVEVSKMKINVTEIP
EEEEECCEEEEEECC		34.56-
176UbiquitinationREDQMRDKLELSFSK
CHHHHHHHEEEEEEC		33.2329967540
180PhosphorylationMRDKLELSFSKSRNG
HHHHEEEEEECCCCC		20.3524719451
182PhosphorylationDKLELSFSKSRNGGG
HHEEEEEECCCCCCC		26.75-
183UbiquitinationKLELSFSKSRNGGGE
HEEEEEECCCCCCCC		51.9622505724
184PhosphorylationLELSFSKSRNGGGEV
EEEEEECCCCCCCCE		29.7629083192
200PhosphorylationRVDYDRQSGSAVITF
EEEECCCCCCEEEEE		35.29-
202PhosphorylationDYDRQSGSAVITFVE
EECCCCCCEEEEEEE		25.30-
206PhosphorylationQSGSAVITFVEIGVA
CCCCEEEEEEEECCH		18.28-
219UbiquitinationVADKILKKKEYPLYI
CHHHHHHCCCCCEEE		47.6022505724
220UbiquitinationADKILKKKEYPLYIN
HHHHHHCCCCCEEEC		61.9829967540
238PhosphorylationHRVTVSPYTEIHLKK
EEEEECCCCEEEEEE		14.97-
244AcetylationPYTEIHLKKYQIFSG
CCCEEEEEEEEEECC		34.9625953088
244UbiquitinationPYTEIHLKKYQIFSG
CCCEEEEEEEEEECC		34.9621890473
244UbiquitinationPYTEIHLKKYQIFSG
CCCEEEEEEEEEECC		34.9621963094
244UbiquitinationPYTEIHLKKYQIFSG
CCCEEEEEEEEEECC		34.9621890473
245UbiquitinationYTEIHLKKYQIFSGT
CCEEEEEEEEEECCC		49.0722817900
245UbiquitinationYTEIHLKKYQIFSGT
CCEEEEEEEEEECCC		49.0721890473
245UbiquitinationYTEIHLKKYQIFSGT
CCEEEEEEEEEECCC		49.0721890473
254UbiquitinationQIFSGTSKRTVLLTG
EEECCCCCCEEEEEE		52.50-
254AcetylationQIFSGTSKRTVLLTG
EEECCCCCCEEEEEE		52.5025953088
284UbiquitinationNIHFQRAKNGGGEVD
HHHHHHCCCCCCCEE		59.3125015289
294UbiquitinationGGEVDVVKCSLGQPH
CCCEEEEEECCCCCE		20.2521963094
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NMI_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NMI_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NMI_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HGS_HUMANHGSphysical
16189514
MESH1_HUMANHDDC3physical
16189514
HHLA3_HUMANHHLA3physical
16189514
EMIL1_HUMANEMILIN1physical
16189514
SNPC5_HUMANSNAPC5physical
16189514
NECP2_HUMANNECAP2physical
16189514
BRCA1_HUMANBRCA1physical
11916966
STA5A_HUMANSTAT5Aphysical
9989503
STAT1_HUMANSTAT1physical
9989503
STAT3_HUMANSTAT3physical
9989503
STA5B_HUMANSTAT5Bphysical
9989503
KAT5_HUMANKAT5physical
17406968
CDN2A_HUMANCDKN2Aphysical
23034180
ARF_HUMANCDKN2Aphysical
23034180
TRIPC_HUMANTRIP12physical
23034180
SOX10_HUMANSOX10physical
16214168
IRF7_HUMANIRF7physical
23956435
KDM1A_HUMANKDM1Aphysical
23455924
OXR1_HUMANOXR1physical
22863883
NMI_HUMANNMIphysical
25416956
MD2BP_HUMANMAD2L1BPphysical
25416956
SNPC5_HUMANSNAPC5physical
25416956
EMIL1_HUMANEMILIN1physical
25416956
HHLA3_HUMANHHLA3physical
25416956
POZP3_HUMANPOMZP3physical
25416956
KDM1A_HUMANKDM1Aphysical
25416956
BRMS1_HUMANBRMS1physical
25416956
CSN7B_HUMANCOPS7Bphysical
25416956
MTMR9_HUMANMTMR9physical
25416956
TBA3E_HUMANTUBA3Ephysical
25416956
SFR1_HUMANSFR1physical
25416956
CA216_HUMANC1orf216physical
25416956
LCA5L_HUMANLCA5Lphysical
25416956
CNKR3_HUMANCNKSR3physical
25416956
TXLNB_HUMANTXLNBphysical
25416956
TXLNA_HUMANTXLNAphysical
25416956
CI072_HUMANC9orf72physical
25416956
MESH1_HUMANHDDC3physical
25416956
CN37_HUMANCNPphysical
26186194
IN35_HUMANIFI35physical
26186194
SYTC2_HUMANTARSL2physical
26186194
ASGL1_HUMANASRGL1physical
26186194
MOCS3_HUMANMOCS3physical
26186194
DCTN3_HUMANDCTN3physical
26186194
NMI_HUMANNMIphysical
21516116
RO52_HUMANTRIM21physical
26342464
IN35_HUMANIFI35physical
26342464
IN35_HUMANIFI35physical
28514442
ASGL1_HUMANASRGL1physical
28514442
SYTC2_HUMANTARSL2physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NMI_HUMAN

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Related Literatures of Post-Translational Modification

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