POZP3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: POZP3_HUMAN
• UniProt AC: Q6PJE2
• Protein Name: POM121 and ZP3 fusion protein
• Gene Name: POMZP3
• Organism: Homo sapiens (Human).
• Sequence Length: 187
• Protein Sequence: MVCSPVTLRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRSCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGLADICQCCNKGDCGTPSHSRRQPRVVSQWSTSASL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MVCSPVTLRIA ----CCCCCEEEEEC	15.82	30001349
7	Phosphorylation	-MVCSPVTLRIAPPD -CCCCCEEEEECCCC	17.44	30001349
18	Phosphorylation	APPDRRFSRSAIPEQ CCCCCCCCCCCCCHH	24.42	26074081
20	Phosphorylation	PDRRFSRSAIPEQII CCCCCCCCCCCHHHH	29.38	30108239
28	Phosphorylation	AIPEQIISSTLSSPS CCCHHHHHHCCCCCC	20.92	30576142
29	Phosphorylation	IPEQIISSTLSSPSS CCHHHHHHCCCCCCC	23.98	30108239
30	Phosphorylation	PEQIISSTLSSPSSN CHHHHHHCCCCCCCC	24.70	25159151
32	Phosphorylation	QIISSTLSSPSSNAP HHHHHCCCCCCCCCC	40.05	25159151
33	Phosphorylation	IISSTLSSPSSNAPD HHHHCCCCCCCCCCC	31.73	30278072
35	Phosphorylation	SSTLSSPSSNAPDPC HHCCCCCCCCCCCHH	37.87	30278072
36	Phosphorylation	STLSSPSSNAPDPCA HCCCCCCCCCCCHHH	40.16	30108239
44	Ubiquitination	NAPDPCAKETVLSAL CCCCHHHHHHHHHHH	61.71	-
46	Phosphorylation	PDPCAKETVLSALKE CCHHHHHHHHHHHHH	26.49	23403867
49	Phosphorylation	CAKETVLSALKEKKK HHHHHHHHHHHHHHH	27.50	30266825
59	Phosphorylation	KEKKKKRTVEEEDQI HHHHHCCCCCHHHCC	40.94	24961811
74	Ubiquitination	FLDGQENKRSCLVDG EECCCCCCCEEEECC	44.96	2190698
136	Ubiquitination	QDPDELNKACSFSKP CCHHHHHHHHCCCCC	64.49	29967540
139	Phosphorylation	DELNKACSFSKPSNS HHHHHHHCCCCCCCC	37.10	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of POZP3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of POZP3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of POZP3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
NMI_HUMAN	NMI	physical	21516116

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.