EIF3L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: EIF3L_HUMAN
• UniProt AC: Q9Y262
• Protein Name: Eukaryotic translation initiation factor 3 subunit L {ECO:0000255|HAMAP-Rule:MF_03011}
• Gene Name: EIF3L {ECO:0000255|HAMAP-Rule:MF_03011}
• Organism: Homo sapiens (Human).
• Sequence Length: 564
• Subcellular Localization: Cytoplasm .
• Protein Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. [PubMed: 17581632]
• Protein Sequence: MSYPADDYESEAAYDPYAYPSDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSYPADDYE ------CCCCCCCCC	39.56	17322308
2	Phosphorylation	------MSYPADDYE ------CCCCCCCCC	39.56	23663014
3	Phosphorylation	-----MSYPADDYES -----CCCCCCCCCC	10.92	23663014
8	Phosphorylation	MSYPADDYESEAAYD CCCCCCCCCCCCCCC	23.15	23663014
10	Phosphorylation	YPADDYESEAAYDPY CCCCCCCCCCCCCCC	26.72	23663014
14	Phosphorylation	DYESEAAYDPYAYPS CCCCCCCCCCCCCCC	25.21	26074081
17	Phosphorylation	SEAAYDPYAYPSDYD CCCCCCCCCCCCCCC	18.83	28450419
19	Phosphorylation	AAYDPYAYPSDYDMH CCCCCCCCCCCCCCC	9.45	26074081
21	Phosphorylation	YDPYAYPSDYDMHTG CCCCCCCCCCCCCCC	35.81	26074081
23	Phosphorylation	PYAYPSDYDMHTGDP CCCCCCCCCCCCCCC	21.36	26074081
27	Phosphorylation	PSDYDMHTGDPKQDL CCCCCCCCCCCHHHH	36.32	26074081
36	Phosphorylation	DPKQDLAYERQYEQQ CCHHHHHHHHHHHHH	20.95	21945579
40	Phosphorylation	DLAYERQYEQQTYQV HHHHHHHHHHHHHHH	23.17	21945579
44	Phosphorylation	ERQYEQQTYQVIPEV HHHHHHHHHHHHHHH	18.67	21945579
45	Phosphorylation	RQYEQQTYQVIPEVI HHHHHHHHHHHHHHH	9.10	21945579
45	Ubiquitination	RQYEQQTYQVIPEVI HHHHHHHHHHHHHHH	9.10	21963094
58	Phosphorylation	VIKNFIQYFHKTVSD HHHHHHHHHHHHHHH	11.66	28152594
61	Ubiquitination	NFIQYFHKTVSDLID HHHHHHHHHHHHHHH	40.50	-
62	Phosphorylation	FIQYFHKTVSDLIDQ HHHHHHHHHHHHHHH	19.37	30622161
64	Phosphorylation	QYFHKTVSDLIDQKV HHHHHHHHHHHHHHH	31.75	21712546
70	Acetylation	VSDLIDQKVYELQAS HHHHHHHHHHHHHHH	42.93	26051181
70	Ubiquitination	VSDLIDQKVYELQAS HHHHHHHHHHHHHHH	42.93	21906983
72	Phosphorylation	DLIDQKVYELQASRV HHHHHHHHHHHHHCC	20.25	28152594
77	Phosphorylation	KVYELQASRVSSDVI HHHHHHHHCCCCHHH	21.91	28152594
80	Phosphorylation	ELQASRVSSDVIDQK HHHHHCCCCHHHCCH	21.51	28985074
81	Phosphorylation	LQASRVSSDVIDQKV HHHHCCCCHHHCCHH	32.80	21712546
87	Ubiquitination	SSDVIDQKVYEIQDI CCHHHCCHHEEHHHH	42.93	21906983
89	Phosphorylation	DVIDQKVYEIQDIYE HHHCCHHEEHHHHHH	17.85	27273156
95	Phosphorylation	VYEIQDIYENSWTKL HEEHHHHHHCCHHHH	19.83	29496907
98	Phosphorylation	IQDIYENSWTKLTER HHHHHHCCHHHHHHH	24.96	30622161
100	Phosphorylation	DIYENSWTKLTERFF HHHHCCHHHHHHHHH	18.92	30622161
101	Ubiquitination	IYENSWTKLTERFFK HHHCCHHHHHHHHHH	47.34	21890473
101	Acetylation	IYENSWTKLTERFFK HHHCCHHHHHHHHHH	47.34	26051181
101	Ubiquitination	IYENSWTKLTERFFK HHHCCHHHHHHHHHH	47.34	21906983
109	Ubiquitination	LTERFFKNTPWPEAE HHHHHHHCCCCHHHH	46.33	24816145
110	Phosphorylation	TERFFKNTPWPEAEA HHHHHHCCCCHHHHH	27.59	28674151
113	Ubiquitination	FFKNTPWPEAEAIAP HHHCCCCHHHHHHCC	31.93	21963094
122	Ubiquitination	AEAIAPQVGNDAVFL HHHHCCCCCCHHHHH	8.23	21963094
130	Ubiquitination	GNDAVFLILYKELYY CCHHHHHHHHHHHHH	2.41	21963094
139	Ubiquitination	YKELYYRHIYAKVSG HHHHHHHHHHHHCCC	10.99	21963094
143	Acetylation	YYRHIYAKVSGGPSL HHHHHHHHCCCCCCH	21.69	26051181
143	Ubiquitination	YYRHIYAKVSGGPSL HHHHHHHHCCCCCCH	21.69	21906983
144	Ubiquitination	YRHIYAKVSGGPSLE HHHHHHHCCCCCCHH	4.97	21963094
145	Phosphorylation	RHIYAKVSGGPSLEQ HHHHHHCCCCCCHHH	37.01	23403867
159	Ubiquitination	QRFESYYNYCNLFNY HHHHHHHHHHHHHHH	27.01	24816145
172	Ubiquitination	NYILNADGPAPLELP HHHHCCCCCCCCCCC	20.19	21963094
186	Ubiquitination	PNQWLWDIIDEFIYQ CCHHHHHHHHHHHHH	2.64	21963094
189	Ubiquitination	WLWDIIDEFIYQFQS HHHHHHHHHHHHHHC	24.44	21963094
203	Ubiquitination	SFSQYRCKTAKKSEE CCCCCCCCCCCCCHH	42.38	22817900
204	Ubiquitination	FSQYRCKTAKKSEEE CCCCCCCCCCCCHHH	47.54	22817900
206	Ubiquitination	QYRCKTAKKSEEEID CCCCCCCCCCHHHHH	63.16	-
207	2-Hydroxyisobutyrylation	YRCKTAKKSEEEIDF CCCCCCCCCHHHHHH	61.71	-
207	Ubiquitination	YRCKTAKKSEEEIDF CCCCCCCCCHHHHHH	61.71	24816145
208	Phosphorylation	RCKTAKKSEEEIDFL CCCCCCCCHHHHHHH	49.92	30622161
220	Ubiquitination	DFLRSNPKIWNVHSV HHHHCCCCHHHHHHH	65.68	21963094
226	Phosphorylation	PKIWNVHSVLNVLHS CCHHHHHHHHHHHHH	24.82	28450419
237	Ubiquitination	VLHSLVDKSNINRQL HHHHHHCCCCCCCEE	37.61	21963094
247	Phosphorylation	INRQLEVYTSGGDPE CCCEEEEEECCCCHH	5.94	20068231
249	Ubiquitination	RQLEVYTSGGDPESV CEEEEEECCCCHHHH	24.08	24816145
250	Ubiquitination	QLEVYTSGGDPESVA EEEEEECCCCHHHHH	36.40	24816145
253	Ubiquitination	VYTSGGDPESVAGEY EEECCCCHHHHHCCC	38.75	22817900
254	Ubiquitination	YTSGGDPESVAGEYG EECCCCHHHHHCCCH	63.69	22817900
255	Phosphorylation	TSGGDPESVAGEYGR ECCCCHHHHHCCCHH	23.74	28152594
258	Ubiquitination	GDPESVAGEYGRHSL CCHHHHHCCCHHHHH	26.88	21963094
260	Phosphorylation	PESVAGEYGRHSLYK HHHHHCCCHHHHHHH	20.67	28152594
263	Ubiquitination	VAGEYGRHSLYKMLG HHCCCHHHHHHHHHH	20.14	21963094
264	Ubiquitination	AGEYGRHSLYKMLGY HCCCHHHHHHHHHHH	31.84	23503661
268	Sulfoxidation	GRHSLYKMLGYFSLV HHHHHHHHHHHHHHH	1.91	28183972
280	Ubiquitination	SLVGLLRLHSLLGDY HHHHHHHHHHHHCHH	3.03	21963094
287	Phosphorylation	LHSLLGDYYQAIKVL HHHHHCHHHHHHHHH	8.83	20090780
288	Phosphorylation	HSLLGDYYQAIKVLE HHHHCHHHHHHHHHH	9.01	20090780
299	Ubiquitination	KVLENIELNKKSMYS HHHHHCCCCCCCHHH	11.45	24816145
301	2-Hydroxyisobutyrylation	LENIELNKKSMYSRV HHHCCCCCCCHHHCC	59.87	-
301	Acetylation	LENIELNKKSMYSRV HHHCCCCCCCHHHCC	59.87	23954790
301	Malonylation	LENIELNKKSMYSRV HHHCCCCCCCHHHCC	59.87	26320211
301	Ubiquitination	LENIELNKKSMYSRV HHHCCCCCCCHHHCC	59.87	27667366
302	Ubiquitination	ENIELNKKSMYSRVP HHCCCCCCCHHHCCC	39.11	22817900
305	Ubiquitination	ELNKKSMYSRVPECQ CCCCCCHHHCCCCCE	10.62	30230243
308	Ubiquitination	KKSMYSRVPECQVTT CCCHHHCCCCCEEEE	3.73	21963094
314	Ubiquitination	RVPECQVTTYYYVGF CCCCCEEEEHHHHHH	5.34	23503661
321	Ubiquitination	TTYYYVGFAYLMMRR EEHHHHHHHHHHHHH	2.63	21890473
339	Ubiquitination	AIRVFANILLYIQRT HHHHHHHHHHHHHHH	2.22	22817900
342	Phosphorylation	VFANILLYIQRTKSM HHHHHHHHHHHHHHH	7.49	-
344	Ubiquitination	ANILLYIQRTKSMFQ HHHHHHHHHHHHHHH	33.17	22817900
345	Ubiquitination	NILLYIQRTKSMFQR HHHHHHHHHHHHHHH	34.26	22817900
347	2-Hydroxyisobutyrylation	LLYIQRTKSMFQRTT HHHHHHHHHHHHHHH	41.95	-
347	Acetylation	LLYIQRTKSMFQRTT HHHHHHHHHHHHHHH	41.95	27452117
347	Ubiquitination	LLYIQRTKSMFQRTT HHHHHHHHHHHHHHH	41.95	24816145
349	Ubiquitination	YIQRTKSMFQRTTYK HHHHHHHHHHHHHHH	3.37	24816145
355	Phosphorylation	SMFQRTTYKYEMINK HHHHHHHHHHHHCCC	15.80	29496907
355	Ubiquitination	SMFQRTTYKYEMINK HHHHHHHHHHHHCCC	15.80	32015554
356	2-Hydroxyisobutyrylation	MFQRTTYKYEMINKQ HHHHHHHHHHHCCCH	32.42	-
356	Acetylation	MFQRTTYKYEMINKQ HHHHHHHHHHHCCCH	32.42	26051181
356	Ubiquitination	MFQRTTYKYEMINKQ HHHHHHHHHHHCCCH	32.42	21906983
357	Phosphorylation	FQRTTYKYEMINKQN HHHHHHHHHHCCCHH	10.58	20090780
362	Ubiquitination	YKYEMINKQNEQMHA HHHHHCCCHHHHHHH	43.50	23503661
367	Ubiquitination	INKQNEQMHALLAIA CCCHHHHHHHHHHHH	1.30	21963094
371	Ubiquitination	NEQMHALLAIALTMY HHHHHHHHHHHHHHC	3.17	21890473
376	Phosphorylation	ALLAIALTMYPMRID HHHHHHHHHCCCCCC	12.97	27251275
385	Phosphorylation	YPMRIDESIHLQLRE CCCCCCCHHHHHHHH	16.15	27251275
386	Ubiquitination	PMRIDESIHLQLREK CCCCCCHHHHHHHHH	3.37	21890473
389	Acetylation	IDESIHLQLREKYGD CCCHHHHHHHHHHHH	25.06	19608861
389	Ubiquitination	IDESIHLQLREKYGD CCCHHHHHHHHHHHH	25.06	22817900
390	Ubiquitination	DESIHLQLREKYGDK CCHHHHHHHHHHHHH	10.85	24816145
393	Ubiquitination	IHLQLREKYGDKMLR HHHHHHHHHHHHHHH	48.37	-
394	Phosphorylation	HLQLREKYGDKMLRM HHHHHHHHHHHHHHH	26.29	-
396	Ubiquitination	QLREKYGDKMLRMQK HHHHHHHHHHHHHCC	30.06	21890473
397	2-Hydroxyisobutyrylation	LREKYGDKMLRMQKG HHHHHHHHHHHHCCC	35.16	-
397	Acetylation	LREKYGDKMLRMQKG HHHHHHHHHHHHCCC	35.16	25953088
397	Malonylation	LREKYGDKMLRMQKG HHHHHHHHHHHHCCC	35.16	26320211
397	Ubiquitination	LREKYGDKMLRMQKG HHHHHHHHHHHHCCC	35.16	24816145
398	Ubiquitination	REKYGDKMLRMQKGD HHHHHHHHHHHCCCC	3.23	23503661
399	Ubiquitination	EKYGDKMLRMQKGDP HHHHHHHHHHCCCCH	5.20	21963094
400	Ubiquitination	KYGDKMLRMQKGDPQ HHHHHHHHHCCCCHH	23.22	23503661
403	Acetylation	DKMLRMQKGDPQVYE HHHHHHCCCCHHHHH	56.81	26051181
403	Malonylation	DKMLRMQKGDPQVYE HHHHHHCCCCHHHHH	56.81	26320211
403	Ubiquitination	DKMLRMQKGDPQVYE HHHHHHCCCCHHHHH	56.81	32015554
404	Ubiquitination	KMLRMQKGDPQVYEE HHHHHCCCCHHHHHH	34.63	21890473
405	Ubiquitination	MLRMQKGDPQVYEEL HHHHCCCCHHHHHHH	37.18	23503661
409	Phosphorylation	QKGDPQVYEELFSYS CCCCHHHHHHHHCCC	9.84	29759185
414	Phosphorylation	QVYEELFSYSCPKFL HHHHHHHCCCCHHHH	28.85	28152594
415	Phosphorylation	VYEELFSYSCPKFLS HHHHHHCCCCHHHHC	13.63	20090780
416	Phosphorylation	YEELFSYSCPKFLSP HHHHHCCCCHHHHCC	23.81	28152594
417	Acetylation	EELFSYSCPKFLSPV HHHHCCCCHHHHCCC	3.01	19608861
417	Glutathionylation	EELFSYSCPKFLSPV HHHHCCCCHHHHCCC	3.01	22555962
417	S-palmitoylation	EELFSYSCPKFLSPV HHHHCCCCHHHHCCC	3.01	29575903
417	Ubiquitination	EELFSYSCPKFLSPV HHHHCCCCHHHHCCC	3.01	27667366
419	Acetylation	LFSYSCPKFLSPVVP HHCCCCHHHHCCCCC	64.36	25953088
419	Ubiquitination	LFSYSCPKFLSPVVP HHCCCCHHHHCCCCC	64.36	21906983
422	Phosphorylation	YSCPKFLSPVVPNYD CCCHHHHCCCCCCCC	20.84	25159151
428	Phosphorylation	LSPVVPNYDNVHPNY HCCCCCCCCCCCCCC	11.65	29496907
434	Ubiquitination	NYDNVHPNYHKEPFL CCCCCCCCCCCCHHH	36.34	24816145
435	Phosphorylation	YDNVHPNYHKEPFLQ CCCCCCCCCCCHHHH	20.79	29496907
436	Ubiquitination	DNVHPNYHKEPFLQQ CCCCCCCCCCHHHHH	34.34	27667366
437	Acetylation	NVHPNYHKEPFLQQL CCCCCCCCCHHHHHH	57.64	23954790
437	Malonylation	NVHPNYHKEPFLQQL CCCCCCCCCHHHHHH	57.64	26320211
437	Ubiquitination	NVHPNYHKEPFLQQL CCCCCCCCCHHHHHH	57.64	22817900
440	Ubiquitination	PNYHKEPFLQQLKVF CCCCCCHHHHHHHHC	11.45	24816145
445	Acetylation	EPFLQQLKVFSDEVQ CHHHHHHHHCCHHHH	36.57	8273333
445	Ubiquitination	EPFLQQLKVFSDEVQ CHHHHHHHHCCHHHH	36.57	-
446	Ubiquitination	PFLQQLKVFSDEVQQ HHHHHHHHCCHHHHH	8.26	21890473
448	Ubiquitination	LQQLKVFSDEVQQQA HHHHHHCCHHHHHHH	35.53	23503661
450	Ubiquitination	QLKVFSDEVQQQAQL HHHHCCHHHHHHHHH	40.82	23503661
451	Ubiquitination	LKVFSDEVQQQAQLS HHHCCHHHHHHHHHH	8.16	33845483
458	Phosphorylation	VQQQAQLSTIRSFLK HHHHHHHHHHHHHHH	15.09	30622161
459	Phosphorylation	QQQAQLSTIRSFLKL HHHHHHHHHHHHHHH	29.06	30622161
461	Ubiquitination	QAQLSTIRSFLKLYT HHHHHHHHHHHHHHH	22.80	21890473
461	Ubiquitination	QAQLSTIRSFLKLYT HHHHHHHHHHHHHHH	22.80	24816145
462	Phosphorylation	AQLSTIRSFLKLYTT HHHHHHHHHHHHHHH	30.95	24719451
462	Ubiquitination	AQLSTIRSFLKLYTT HHHHHHHHHHHHHHH	30.95	21890473
465	Acetylation	STIRSFLKLYTTMPV HHHHHHHHHHHHHCH	37.12	19608861
465	Ubiquitination	STIRSFLKLYTTMPV HHHHHHHHHHHHHCH	37.12	21906983
470	Sulfoxidation	FLKLYTTMPVAKLAG HHHHHHHHCHHHHHC	1.61	30846556
474	Ubiquitination	YTTMPVAKLAGFLDL HHHHCHHHHHCCCCC	38.82	-
480	Ubiquitination	AKLAGFLDLTEQEFR HHHHCCCCCCCCHHH	49.65	21890473
486	Ubiquitination	LDLTEQEFRIQLLVF CCCCCCHHHHHHHHH	9.24	27667366
494	Acetylation	RIQLLVFKHKMKNLV HHHHHHHHHHCCCCC	34.53	26051181
494	Ubiquitination	RIQLLVFKHKMKNLV HHHHHHHHHHCCCCC	34.53	21890473
496	Ubiquitination	QLLVFKHKMKNLVWT HHHHHHHHCCCCCCC	52.76	23503661
498	Ubiquitination	LVFKHKMKNLVWTSG HHHHHHCCCCCCCCC	52.51	23503661
501	Acetylation	KHKMKNLVWTSGISA HHHCCCCCCCCCHHH	7.97	19608861
501	Ubiquitination	KHKMKNLVWTSGISA HHHCCCCCCCCCHHH	7.97	33845483
508	Ubiquitination	VWTSGISALDGEFQS CCCCCHHHCCCCCCC	14.04	21963094
511	Ubiquitination	SGISALDGEFQSASE CCHHHCCCCCCCHHE	38.17	24816145
534	2-Hydroxyisobutyrylation	MIHIADTKVARRYGD HEEECCHHHHHHHHH	34.15	-
534	Ubiquitination	MIHIADTKVARRYGD HEEECCHHHHHHHHH	34.15	21906983
537	Ubiquitination	IADTKVARRYGDFFI ECCHHHHHHHHHHHH	35.03	21890473
539	Phosphorylation	DTKVARRYGDFFIRQ CHHHHHHHHHHHHHH	18.59	28152594
539	Ubiquitination	DTKVARRYGDFFIRQ CHHHHHHHHHHHHHH	18.59	23503661
541	Ubiquitination	KVARRYGDFFIRQIH HHHHHHHHHHHHHHH	26.75	23503661
549	Acetylation	FFIRQIHKFEELNRT HHHHHHHHHHHHHHH	56.98	19608861
549	Malonylation	FFIRQIHKFEELNRT HHHHHHHHHHHHHHH	56.98	26320211
549	Ubiquitination	FFIRQIHKFEELNRT HHHHHHHHHHHHHHH	56.98	33845483
556	Phosphorylation	KFEELNRTLKKMGQR HHHHHHHHHHHHCCC	41.68	23186163
558	Methylation	EELNRTLKKMGQRP- HHHHHHHHHHCCCC-	39.85	-
559	Ubiquitination	ELNRTLKKMGQRP-- HHHHHHHHHCCCC--	51.91	24816145
575	Ubiquitination	------------------ ------------------		24816145

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of EIF3L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of EIF3L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of EIF3L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EIF3D_HUMAN	EIF3D	physical	11590142
EIF3A_HUMAN	EIF3A	physical	11590142
EIF3E_HUMAN	EIF3E	physical	11590142
EIF3B_HUMAN	EIF3B	physical	18599441
EIF3M_HUMAN	EIF3M	physical	22939629
NUCL_HUMAN	NCL	physical	22939629
RRN3_HUMAN	RRN3	physical	12393749
DDX3X_HUMAN	DDX3X	physical	22863883
EIF3A_HUMAN	EIF3A	physical	22863883
EIF3C_HUMAN	EIF3C	physical	22863883
EIF3D_HUMAN	EIF3D	physical	22863883
EIF3E_HUMAN	EIF3E	physical	22863883
EIF3K_HUMAN	EIF3K	physical	22863883
EIF3H_HUMAN	EIF3H	physical	22863883
LARP1_HUMAN	LARP1	physical	22863883
RS13_HUMAN	RPS13	physical	22863883
RS16_HUMAN	RPS16	physical	22863883
RS18_HUMAN	RPS18	physical	22863883
RS20_HUMAN	RPS20	physical	22863883
RS25_HUMAN	RPS25	physical	22863883
RS28_HUMAN	RPS28	physical	22863883
RS4X_HUMAN	RPS4X	physical	22863883
RS5_HUMAN	RPS5	physical	22863883
RS8_HUMAN	RPS8	physical	22863883
RS9_HUMAN	RPS9	physical	22863883
EIF3A_HUMAN	EIF3A	physical	26344197
EIF3B_HUMAN	EIF3B	physical	26344197
EIF3C_HUMAN	EIF3C	physical	26344197
EIFCL_HUMAN	EIF3CL	physical	26344197
EIF3D_HUMAN	EIF3D	physical	26344197
EIF3F_HUMAN	EIF3F	physical	26344197
EIF3G_HUMAN	EIF3G	physical	26344197
EIF3H_HUMAN	EIF3H	physical	26344197
EIF3K_HUMAN	EIF3K	physical	26344197
EIF3M_HUMAN	EIF3M	physical	26344197
NUCL_HUMAN	NCL	physical	26344197
NUMA1_HUMAN	NUMA1	physical	26344197
EIFCL_HUMAN	EIF3CL	physical	28514442
PRC2B_HUMAN	PRRC2B	physical	28514442
EIF3A_HUMAN	EIF3A	physical	28514442
EIF3C_HUMAN	EIF3C	physical	28514442
EIF3K_HUMAN	EIF3K	physical	28514442
EIF3D_HUMAN	EIF3D	physical	28514442
EIF3B_HUMAN	EIF3B	physical	28514442
ZN746_HUMAN	ZNF746	physical	28514442
GBB2_HUMAN	GNB2	physical	28514442
TT21B_HUMAN	TTC21B	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Structural characterization of the human eukaryotic initiation factor3 protein complex by mass spectrometry.";
Damoc E., Fraser C.S., Zhou M., Videler H., Mayeur G.L.,Hershey J.W.B., Doudna J.A., Robinson C.V., Leary J.A.;
Mol. Cell. Proteomics 6:1135-1146(2007).
Cited for: IDENTIFICATION IN THE EIF-3 COMPLEX, CHARACTERIZATION OF THE EIF-3COMPLEX, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT SER-2, ANDMASS SPECTROMETRY.
PubMed: 17322308

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-437; LYS-465 AND LYS-549,AND MASS SPECTROMETRY.
PubMed: 19608861