| UniProt ID | ATX2L_HUMAN | |
|---|---|---|
| UniProt AC | Q8WWM7 | |
| Protein Name | Ataxin-2-like protein | |
| Gene Name | ATXN2L | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1075 | |
| Subcellular Localization |
Membrane Peripheral membrane protein . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition |
|
| Protein Description | Involved in the regulation of stress granule and P-body formation.. | |
| Protein Sequence | MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MLKPQPLQ -------CCCCCCCC | 45.87 | 22814378 | |
| 11 | Phosphorylation | PQPLQQPSQPQQPPP CCCCCCCCCCCCCCC | 50.59 | 26074081 | |
| 19 | Phosphorylation | QPQQPPPTQQAVARR CCCCCCCCCCHHHCC | 38.80 | 26074081 | |
| 31 | Phosphorylation | ARRPPGGTSPPNGGL HCCCCCCCCCCCCCC | 43.93 | 23927012 | |
| 31 (in isoform 2) | Phosphorylation | - | 43.93 | - | |
| 31 (in isoform 3) | Phosphorylation | - | 43.93 | 21406692 | |
| 31 (in isoform 4) | Phosphorylation | - | 43.93 | - | |
| 31 (in isoform 7) | Phosphorylation | - | 43.93 | - | |
| 31 (in isoform 8) | Phosphorylation | - | 43.93 | - | |
| 32 | Phosphorylation | RRPPGGTSPPNGGLP CCCCCCCCCCCCCCC | 41.45 | 30278072 | |
| 32 (in isoform 2) | Phosphorylation | - | 41.45 | - | |
| 32 (in isoform 3) | Phosphorylation | - | 41.45 | - | |
| 32 (in isoform 4) | Phosphorylation | - | 41.45 | - | |
| 32 (in isoform 7) | Phosphorylation | - | 41.45 | - | |
| 32 (in isoform 8) | Phosphorylation | - | 41.45 | - | |
| 44 | Phosphorylation | GLPGPLATSAAPPGP CCCCCCCCCCCCCCC | 26.95 | 23927012 | |
| 44 (in isoform 2) | Phosphorylation | - | 26.95 | - | |
| 44 (in isoform 3) | Phosphorylation | - | 26.95 | 27251275 | |
| 44 (in isoform 4) | Phosphorylation | - | 26.95 | - | |
| 44 (in isoform 7) | Phosphorylation | - | 26.95 | - | |
| 44 (in isoform 8) | Phosphorylation | - | 26.95 | - | |
| 45 | Phosphorylation | LPGPLATSAAPPGPP CCCCCCCCCCCCCCC | 19.47 | 30278072 | |
| 45 (in isoform 2) | Phosphorylation | - | 19.47 | - | |
| 45 (in isoform 3) | Phosphorylation | - | 19.47 | - | |
| 45 (in isoform 4) | Phosphorylation | - | 19.47 | - | |
| 45 (in isoform 7) | Phosphorylation | - | 19.47 | - | |
| 45 (in isoform 8) | Phosphorylation | - | 19.47 | - | |
| 56 | Phosphorylation | PGPPAAASPCLGPVA CCCCCCCCCCCHHHH | 16.06 | 23927012 | |
| 56 (in isoform 3) | Phosphorylation | - | 16.06 | 27251275 | |
| 67 | Phosphorylation | GPVAAAGSGLRRGAE HHHHHCCCCCCCCCC | 29.90 | 23927012 | |
| 67 (in isoform 2) | Phosphorylation | - | 29.90 | - | |
| 67 (in isoform 3) | Phosphorylation | - | 29.90 | - | |
| 67 (in isoform 4) | Phosphorylation | - | 29.90 | - | |
| 67 (in isoform 7) | Phosphorylation | - | 29.90 | - | |
| 67 (in isoform 8) | Phosphorylation | - | 29.90 | - | |
| 71 | Methylation | AAGSGLRRGAEGILA HCCCCCCCCCCCCCC | 54.43 | - | |
| 98 | Phosphorylation | PGAAAIGSARGQSTG CCCCEECCCCCCCCC | 14.53 | 25159151 | |
| 103 | Phosphorylation | IGSARGQSTGKGPPQ ECCCCCCCCCCCCCC | 41.78 | 23927012 | |
| 103 (in isoform 2) | Phosphorylation | - | 41.78 | - | |
| 103 (in isoform 3) | Phosphorylation | - | 41.78 | - | |
| 103 (in isoform 4) | Phosphorylation | - | 41.78 | - | |
| 103 (in isoform 7) | Phosphorylation | - | 41.78 | - | |
| 103 (in isoform 8) | Phosphorylation | - | 41.78 | - | |
| 104 | Phosphorylation | GSARGQSTGKGPPQS CCCCCCCCCCCCCCC | 34.72 | 23927012 | |
| 106 | Acetylation | ARGQSTGKGPPQSPV CCCCCCCCCCCCCCC | 69.22 | 25953088 | |
| 106 | Ubiquitination | ARGQSTGKGPPQSPV CCCCCCCCCCCCCCC | 69.22 | - | |
| 111 | Phosphorylation | TGKGPPQSPVFEGVY CCCCCCCCCCEECCC | 28.89 | 19664994 | |
| 111 (in isoform 2) | Phosphorylation | - | 28.89 | - | |
| 111 (in isoform 3) | Phosphorylation | - | 28.89 | 24719451 | |
| 111 (in isoform 4) | Phosphorylation | - | 28.89 | - | |
| 111 (in isoform 7) | Phosphorylation | - | 28.89 | - | |
| 111 (in isoform 8) | Phosphorylation | - | 28.89 | - | |
| 118 | Phosphorylation | SPVFEGVYNNSRMLH CCCEECCCCCHHHHH | 21.34 | 23927012 | |
| 118 (in isoform 3) | Phosphorylation | - | 21.34 | 25147952 | |
| 121 | Phosphorylation | FEGVYNNSRMLHFLT EECCCCCHHHHHHHH | 18.54 | 23927012 | |
| 121 (in isoform 2) | Phosphorylation | - | 18.54 | - | |
| 121 (in isoform 3) | Phosphorylation | - | 18.54 | - | |
| 121 (in isoform 4) | Phosphorylation | - | 18.54 | - | |
| 121 (in isoform 7) | Phosphorylation | - | 18.54 | - | |
| 121 (in isoform 8) | Phosphorylation | - | 18.54 | - | |
| 128 | Phosphorylation | SRMLHFLTAVVGSTC HHHHHHHHHHHCCCC | 19.23 | 20068231 | |
| 133 | Phosphorylation | FLTAVVGSTCDVKVK HHHHHHCCCCEEECC | 17.79 | 26503514 | |
| 134 | Phosphorylation | LTAVVGSTCDVKVKN HHHHHCCCCEEECCC | 13.54 | 20068231 | |
| 134 (in isoform 2) | Phosphorylation | - | 13.54 | - | |
| 134 (in isoform 3) | Phosphorylation | - | 13.54 | - | |
| 134 (in isoform 4) | Phosphorylation | - | 13.54 | - | |
| 134 (in isoform 7) | Phosphorylation | - | 13.54 | - | |
| 134 (in isoform 8) | Phosphorylation | - | 13.54 | - | |
| 138 | Acetylation | VGSTCDVKVKNGTTY HCCCCEEECCCCCEE | 33.95 | 26051181 | |
| 138 | Ubiquitination | VGSTCDVKVKNGTTY HCCCCEEECCCCCEE | 33.95 | - | |
| 140 | Ubiquitination | STCDVKVKNGTTYEG CCCEEECCCCCEEEH | 43.90 | - | |
| 143 | Phosphorylation | DVKVKNGTTYEGIFK EEECCCCCEEEHHHH | 35.28 | 28152594 | |
| 144 | Phosphorylation | VKVKNGTTYEGIFKT EECCCCCEEEHHHHH | 22.45 | 28152594 | |
| 145 | Phosphorylation | KVKNGTTYEGIFKTL ECCCCCEEEHHHHHH | 16.40 | 28152594 | |
| 145 (in isoform 3) | Phosphorylation | - | 16.40 | 25147952 | |
| 150 | Ubiquitination | TTYEGIFKTLSSKFE CEEEHHHHHHHHHHH | 46.78 | - | |
| 151 | Phosphorylation | TYEGIFKTLSSKFEL EEEHHHHHHHHHHHH | 22.56 | 30622161 | |
| 155 | Acetylation | IFKTLSSKFELAVDA HHHHHHHHHHHHHHH | 39.21 | 26051181 | |
| 155 | Ubiquitination | IFKTLSSKFELAVDA HHHHHHHHHHHHHHH | 39.21 | - | |
| 166 | Ubiquitination | AVDAVHRKASEPAGG HHHHHHHHHCCCCCC | 41.19 | - | |
| 168 | Phosphorylation | DAVHRKASEPAGGPR HHHHHHHCCCCCCCC | 47.34 | 28348404 | |
| 168 (in isoform 3) | Phosphorylation | - | 47.34 | 27251275 | |
| 202 | Phosphorylation | FRNVDFNYATKDKFT EECCCCCCCCCCCCC | 18.68 | 28064214 | |
| 204 | Phosphorylation | NVDFNYATKDKFTDS CCCCCCCCCCCCCCC | 29.43 | - | |
| 205 | Ubiquitination | VDFNYATKDKFTDSA CCCCCCCCCCCCCCH | 51.23 | 21906983 | |
| 205 (in isoform 1) | Ubiquitination | - | 51.23 | 21890473 | |
| 205 (in isoform 2) | Ubiquitination | - | 51.23 | 21890473 | |
| 205 (in isoform 3) | Ubiquitination | - | 51.23 | 21890473 | |
| 205 (in isoform 4) | Ubiquitination | - | 51.23 | 21890473 | |
| 205 (in isoform 5) | Ubiquitination | - | 51.23 | 21890473 | |
| 205 (in isoform 6) | Ubiquitination | - | 51.23 | 21890473 | |
| 205 (in isoform 7) | Ubiquitination | - | 51.23 | 21890473 | |
| 207 | Ubiquitination | FNYATKDKFTDSAIA CCCCCCCCCCCCHHH | 52.28 | 21890473 | |
| 207 | Ubiquitination | FNYATKDKFTDSAIA CCCCCCCCCCCCHHH | 52.28 | 21890473 | |
| 207 | Acetylation | FNYATKDKFTDSAIA CCCCCCCCCCCCHHH | 52.28 | 26822725 | |
| 207 | Ubiquitination | FNYATKDKFTDSAIA CCCCCCCCCCCCHHH | 52.28 | 21890473 | |
| 207 (in isoform 1) | Ubiquitination | - | 52.28 | 21890473 | |
| 207 (in isoform 2) | Ubiquitination | - | 52.28 | 21890473 | |
| 207 (in isoform 3) | Ubiquitination | - | 52.28 | 21890473 | |
| 207 (in isoform 4) | Ubiquitination | - | 52.28 | 21890473 | |
| 207 (in isoform 5) | Ubiquitination | - | 52.28 | 21890473 | |
| 207 (in isoform 6) | Ubiquitination | - | 52.28 | 21890473 | |
| 207 (in isoform 7) | Ubiquitination | - | 52.28 | 21890473 | |
| 209 | Phosphorylation | YATKDKFTDSAIAMN CCCCCCCCCCHHHHC | 34.48 | 28555341 | |
| 211 | Phosphorylation | TKDKFTDSAIAMNSK CCCCCCCCHHHHCCC | 20.65 | 21815630 | |
| 211 (in isoform 3) | Phosphorylation | - | 20.65 | 27251275 | |
| 215 | Sulfoxidation | FTDSAIAMNSKVNGE CCCCHHHHCCCCCCH | 4.80 | 21406390 | |
| 217 | Phosphorylation | DSAIAMNSKVNGEHK CCHHHHCCCCCCHHH | 25.54 | 28555341 | |
| 218 | Ubiquitination | SAIAMNSKVNGEHKE CHHHHCCCCCCHHHH | 34.41 | - | |
| 236 | Phosphorylation | QRWEGGDSNSDDYDL HHHCCCCCCCCCCCC | 41.32 | 22115753 | |
| 236 (in isoform 3) | Phosphorylation | - | 41.32 | 27251275 | |
| 238 | Phosphorylation | WEGGDSNSDDYDLES HCCCCCCCCCCCCHH | 35.49 | 22115753 | |
| 238 (in isoform 3) | Phosphorylation | - | 35.49 | 24719451 | |
| 241 | Phosphorylation | GDSNSDDYDLESDMS CCCCCCCCCCHHHHC | 27.67 | 28450419 | |
| 241 (in isoform 2) | Phosphorylation | - | 27.67 | - | |
| 241 (in isoform 3) | Phosphorylation | - | 27.67 | - | |
| 241 (in isoform 4) | Phosphorylation | - | 27.67 | - | |
| 241 (in isoform 7) | Phosphorylation | - | 27.67 | - | |
| 241 (in isoform 8) | Phosphorylation | - | 27.67 | - | |
| 245 | Phosphorylation | SDDYDLESDMSNGWD CCCCCCHHHHCCCCC | 46.00 | 21406692 | |
| 248 | Phosphorylation | YDLESDMSNGWDPNE CCCHHHHCCCCCHHH | 36.86 | 21406692 | |
| 264 | Phosphorylation | FKFNEENYGVKTTYD HCCCHHHCCCEEEEC | 26.95 | 25159151 | |
| 264 (in isoform 2) | Phosphorylation | - | 26.95 | - | |
| 264 (in isoform 3) | Phosphorylation | - | 26.95 | - | |
| 264 (in isoform 4) | Phosphorylation | - | 26.95 | - | |
| 264 (in isoform 7) | Phosphorylation | - | 26.95 | - | |
| 264 (in isoform 8) | Phosphorylation | - | 26.95 | - | |
| 267 | Ubiquitination | NEENYGVKTTYDSSL CHHHCCCEEEECCCC | 30.68 | 21906983 | |
| 267 (in isoform 1) | Ubiquitination | - | 30.68 | 21890473 | |
| 267 (in isoform 2) | Ubiquitination | - | 30.68 | 21890473 | |
| 267 (in isoform 3) | Ubiquitination | - | 30.68 | 21890473 | |
| 267 (in isoform 4) | Ubiquitination | - | 30.68 | 21890473 | |
| 267 (in isoform 5) | Ubiquitination | - | 30.68 | 21890473 | |
| 267 (in isoform 6) | Ubiquitination | - | 30.68 | 21890473 | |
| 267 (in isoform 7) | Ubiquitination | - | 30.68 | 21890473 | |
| 268 | Phosphorylation | EENYGVKTTYDSSLS HHHCCCEEEECCCCC | 28.34 | 28796482 | |
| 269 | O-linked_Glycosylation | ENYGVKTTYDSSLSS HHCCCEEEECCCCCC | 21.44 | 30059200 | |
| 269 | Phosphorylation | ENYGVKTTYDSSLSS HHCCCEEEECCCCCC | 21.44 | 28796482 | |
| 270 | Phosphorylation | NYGVKTTYDSSLSSY HCCCEEEECCCCCCE | 21.04 | 28796482 | |
| 272 | Phosphorylation | GVKTTYDSSLSSYTV CCEEEECCCCCCEEE | 23.82 | 28796482 | |
| 273 | Phosphorylation | VKTTYDSSLSSYTVP CEEEECCCCCCEEEE | 29.40 | 29978859 | |
| 275 | Phosphorylation | TTYDSSLSSYTVPLE EEECCCCCCEEEECC | 24.21 | 28796482 | |
| 276 | Phosphorylation | TYDSSLSSYTVPLEK EECCCCCCEEEECCC | 30.07 | 28796482 | |
| 276 (in isoform 3) | Phosphorylation | - | 30.07 | 27251275 | |
| 277 | Phosphorylation | YDSSLSSYTVPLEKD ECCCCCCEEEECCCC | 14.37 | 28796482 | |
| 277 (in isoform 2) | Phosphorylation | - | 14.37 | - | |
| 277 (in isoform 3) | Phosphorylation | - | 14.37 | - | |
| 277 (in isoform 4) | Phosphorylation | - | 14.37 | - | |
| 277 (in isoform 7) | Phosphorylation | - | 14.37 | - | |
| 277 (in isoform 8) | Phosphorylation | - | 14.37 | - | |
| 278 | Phosphorylation | DSSLSSYTVPLEKDN CCCCCCEEEECCCCC | 20.00 | 28796482 | |
| 283 | Acetylation | SYTVPLEKDNSEEFR CEEEECCCCCCHHHH | 70.64 | 26051181 | |
| 283 | Ubiquitination | SYTVPLEKDNSEEFR CEEEECCCCCCHHHH | 70.64 | - | |
| 286 | Phosphorylation | VPLEKDNSEEFRQRE EECCCCCCHHHHHHH | 48.95 | 25159151 | |
| 305 | Phosphorylation | QLAREIESSPQYRLR HHHHHHHCCCCEEEE | 53.64 | 22167270 | |
| 306 | Phosphorylation | LAREIESSPQYRLRI HHHHHHCCCCEEEEE | 11.84 | 19664994 | |
| 306 (in isoform 2) | Phosphorylation | - | 11.84 | - | |
| 306 (in isoform 3) | Phosphorylation | - | 11.84 | 24719451 | |
| 306 (in isoform 4) | Phosphorylation | - | 11.84 | - | |
| 306 (in isoform 7) | Phosphorylation | - | 11.84 | - | |
| 306 (in isoform 8) | Phosphorylation | - | 11.84 | - | |
| 309 | Phosphorylation | EIESSPQYRLRIAME HHHCCCCEEEEEEEE | 18.26 | 21955146 | |
| 309 (in isoform 2) | Phosphorylation | - | 18.26 | - | |
| 309 (in isoform 3) | Phosphorylation | - | 18.26 | - | |
| 309 (in isoform 4) | Phosphorylation | - | 18.26 | - | |
| 309 (in isoform 7) | Phosphorylation | - | 18.26 | - | |
| 309 (in isoform 8) | Phosphorylation | - | 18.26 | - | |
| 322 | Phosphorylation | MENDDGRTEEEKHSA EECCCCCCHHHHHHH | 53.96 | - | |
| 326 | Acetylation | DGRTEEEKHSAVQRQ CCCCHHHHHHHHHHC | 46.25 | 26051181 | |
| 328 | Phosphorylation | RTEEEKHSAVQRQGS CCHHHHHHHHHHCCC | 41.00 | 26074081 | |
| 335 | Phosphorylation | SAVQRQGSGRESPSL HHHHHCCCCCCCCCH | 26.75 | 29255136 | |
| 335 (in isoform 2) | Phosphorylation | - | 26.75 | - | |
| 335 (in isoform 3) | Phosphorylation | - | 26.75 | 24719451 | |
| 335 (in isoform 4) | Phosphorylation | - | 26.75 | - | |
| 335 (in isoform 7) | Phosphorylation | - | 26.75 | - | |
| 335 (in isoform 8) | Phosphorylation | - | 26.75 | - | |
| 339 | Phosphorylation | RQGSGRESPSLASRE HCCCCCCCCCHHHCC | 20.59 | 29255136 | |
| 339 (in isoform 2) | Phosphorylation | - | 20.59 | - | |
| 339 (in isoform 3) | Phosphorylation | - | 20.59 | 24719451 | |
| 339 (in isoform 4) | Phosphorylation | - | 20.59 | - | |
| 339 (in isoform 7) | Phosphorylation | - | 20.59 | - | |
| 339 (in isoform 8) | Phosphorylation | - | 20.59 | - | |
| 341 | Phosphorylation | GSGRESPSLASREGK CCCCCCCCHHHCCCC | 45.94 | 29255136 | |
| 341 (in isoform 2) | Phosphorylation | - | 45.94 | - | |
| 341 (in isoform 3) | Phosphorylation | - | 45.94 | 21406692 | |
| 341 (in isoform 4) | Phosphorylation | - | 45.94 | - | |
| 341 (in isoform 7) | Phosphorylation | - | 45.94 | - | |
| 341 (in isoform 8) | Phosphorylation | - | 45.94 | - | |
| 344 | Phosphorylation | RESPSLASREGKYIP CCCCCHHHCCCCCCC | 35.84 | 23927012 | |
| 344 (in isoform 2) | Phosphorylation | - | 35.84 | - | |
| 344 (in isoform 3) | Phosphorylation | - | 35.84 | - | |
| 344 (in isoform 4) | Phosphorylation | - | 35.84 | - | |
| 344 (in isoform 7) | Phosphorylation | - | 35.84 | - | |
| 344 (in isoform 8) | Phosphorylation | - | 35.84 | - | |
| 348 | Acetylation | SLASREGKYIPLPQR CHHHCCCCCCCCCHH | 34.94 | 23749302 | |
| 348 | Malonylation | SLASREGKYIPLPQR CHHHCCCCCCCCCHH | 34.94 | 26320211 | |
| 348 | Sumoylation | SLASREGKYIPLPQR CHHHCCCCCCCCCHH | 34.94 | 28112733 | |
| 348 | Ubiquitination | SLASREGKYIPLPQR CHHHCCCCCCCCCHH | 34.94 | 19608861 | |
| 348 (in isoform 2) | Acetylation | - | 34.94 | - | |
| 348 (in isoform 3) | Acetylation | - | 34.94 | - | |
| 348 (in isoform 4) | Acetylation | - | 34.94 | - | |
| 348 (in isoform 8) | Acetylation | - | 34.94 | - | |
| 349 | Phosphorylation | LASREGKYIPLPQRV HHHCCCCCCCCCHHH | 20.73 | 27155012 | |
| 349 (in isoform 2) | Phosphorylation | - | 20.73 | - | |
| 349 (in isoform 3) | Phosphorylation | - | 20.73 | 27642862 | |
| 349 (in isoform 4) | Phosphorylation | - | 20.73 | - | |
| 349 (in isoform 7) | Phosphorylation | - | 20.73 | 15144186 | |
| 349 (in isoform 8) | Phosphorylation | - | 20.73 | - | |
| 361 | Asymmetric dimethylarginine | QRVREGPRGGVRCSS HHHCCCCCCCCCCCC | 66.41 | - | |
| 361 | Methylation | QRVREGPRGGVRCSS HHHCCCCCCCCCCCC | 66.41 | 25748791 | |
| 361 (in isoform 2) | Methylation | - | 66.41 | - | |
| 361 (in isoform 3) | Methylation | - | 66.41 | - | |
| 361 (in isoform 4) | Methylation | - | 66.41 | - | |
| 361 (in isoform 8) | Methylation | - | 66.41 | - | |
| 365 | Methylation | EGPRGGVRCSSSRGG CCCCCCCCCCCCCCC | 20.20 | - | |
| 369 | O-linked_Glycosylation | GGVRCSSSRGGRPGL CCCCCCCCCCCCCCC | 20.74 | 30059200 | |
| 370 | Methylation | GVRCSSSRGGRPGLS CCCCCCCCCCCCCCC | 54.24 | - | |
| 373 | Methylation | CSSSRGGRPGLSSLP CCCCCCCCCCCCCCC | 25.57 | - | |
| 377 | Phosphorylation | RGGRPGLSSLPPRGP CCCCCCCCCCCCCCC | 35.43 | 23312004 | |
| 378 | Phosphorylation | GGRPGLSSLPPRGPH CCCCCCCCCCCCCCC | 50.35 | 27470641 | |
| 378 (in isoform 2) | Phosphorylation | - | 50.35 | - | |
| 378 (in isoform 3) | Phosphorylation | - | 50.35 | - | |
| 378 (in isoform 4) | Phosphorylation | - | 50.35 | - | |
| 378 (in isoform 8) | Phosphorylation | - | 50.35 | - | |
| 382 | Methylation | GLSSLPPRGPHHLDN CCCCCCCCCCCCCCC | 70.14 | - | |
| 390 | Phosphorylation | GPHHLDNSSPGPGSE CCCCCCCCCCCCCCC | 37.26 | 23401153 | |
| 390 (in isoform 2) | Phosphorylation | - | 37.26 | - | |
| 390 (in isoform 3) | Phosphorylation | - | 37.26 | 21406692 | |
| 390 (in isoform 4) | Phosphorylation | - | 37.26 | - | |
| 390 (in isoform 8) | Phosphorylation | - | 37.26 | - | |
| 391 | Phosphorylation | PHHLDNSSPGPGSEA CCCCCCCCCCCCCCC | 39.88 | 29255136 | |
| 391 (in isoform 2) | Phosphorylation | - | 39.88 | - | |
| 391 (in isoform 3) | Phosphorylation | - | 39.88 | 24719451 | |
| 391 (in isoform 4) | Phosphorylation | - | 39.88 | - | |
| 391 (in isoform 8) | Phosphorylation | - | 39.88 | - | |
| 396 | Phosphorylation | NSSPGPGSEARGING CCCCCCCCCCCCCCC | 31.08 | 29255136 | |
| 399 | Methylation | PGPGSEARGINGGPS CCCCCCCCCCCCCCC | 42.33 | - | |
| 406 | Phosphorylation | RGINGGPSRMSPKAQ CCCCCCCCCCCHHHC | 43.84 | 30266825 | |
| 406 (in isoform 2) | Phosphorylation | - | 43.84 | - | |
| 406 (in isoform 3) | Phosphorylation | - | 43.84 | - | |
| 406 (in isoform 4) | Phosphorylation | - | 43.84 | - | |
| 406 (in isoform 8) | Phosphorylation | - | 43.84 | - | |
| 409 | Phosphorylation | NGGPSRMSPKAQRPL CCCCCCCCHHHCCCC | 23.34 | 26846344 | |
| 409 (in isoform 2) | Phosphorylation | - | 23.34 | - | |
| 409 (in isoform 3) | Phosphorylation | - | 23.34 | 21406692 | |
| 409 (in isoform 4) | Phosphorylation | - | 23.34 | - | |
| 409 (in isoform 8) | Phosphorylation | - | 23.34 | - | |
| 414 | Methylation | RMSPKAQRPLRGAKT CCCHHHCCCCCCCCC | 36.76 | - | |
| 417 | Methylation | PKAQRPLRGAKTLSS HHHCCCCCCCCCCCC | 45.78 | - | |
| 421 | Phosphorylation | RPLRGAKTLSSPSNR CCCCCCCCCCCCCCC | 31.19 | 30278072 | |
| 423 | Phosphorylation | LRGAKTLSSPSNRPS CCCCCCCCCCCCCCC | 45.49 | 22167270 | |
| 423 (in isoform 2) | Phosphorylation | - | 45.49 | - | |
| 423 (in isoform 3) | Phosphorylation | - | 45.49 | 24719451 | |
| 423 (in isoform 4) | Phosphorylation | - | 45.49 | - | |
| 423 (in isoform 8) | Phosphorylation | - | 45.49 | - | |
| 424 | Phosphorylation | RGAKTLSSPSNRPSG CCCCCCCCCCCCCCC | 35.15 | 22167270 | |
| 424 (in isoform 2) | Phosphorylation | - | 35.15 | - | |
| 424 (in isoform 3) | Phosphorylation | - | 35.15 | - | |
| 424 (in isoform 4) | Phosphorylation | - | 35.15 | - | |
| 424 (in isoform 8) | Phosphorylation | - | 35.15 | - | |
| 426 | Phosphorylation | AKTLSSPSNRPSGET CCCCCCCCCCCCCCC | 47.63 | 30266825 | |
| 428 | Methylation | TLSSPSNRPSGETSV CCCCCCCCCCCCCCC | 30.97 | - | |
| 430 | Phosphorylation | SSPSNRPSGETSVPP CCCCCCCCCCCCCCC | 46.13 | 22167270 | |
| 430 (in isoform 3) | Phosphorylation | - | 46.13 | 24719451 | |
| 433 | Phosphorylation | SNRPSGETSVPPPPA CCCCCCCCCCCCCCC | 38.25 | 22167270 | |
| 434 | Phosphorylation | NRPSGETSVPPPPAV CCCCCCCCCCCCCCC | 28.46 | 21955146 | |
| 445 | Phosphorylation | PPAVGRMYPPRSPKS CCCCCCCCCCCCCCC | 14.55 | 27461979 | |
| 445 (in isoform 3) | Phosphorylation | - | 14.55 | 27251275 | |
| 449 | Phosphorylation | GRMYPPRSPKSAAPA CCCCCCCCCCCCCCC | 42.31 | 29255136 | |
| 449 (in isoform 2) | Phosphorylation | - | 42.31 | - | |
| 449 (in isoform 3) | Phosphorylation | - | 42.31 | 24719451 | |
| 449 (in isoform 4) | Phosphorylation | - | 42.31 | - | |
| 449 (in isoform 8) | Phosphorylation | - | 42.31 | - | |
| 452 | Phosphorylation | YPPRSPKSAAPAPIS CCCCCCCCCCCCCCC | 32.80 | 26552605 | |
| 459 | Phosphorylation | SAAPAPISASCPEPP CCCCCCCCCCCCCCC | 17.05 | 26552605 | |
| 461 | O-linked_Glycosylation | APAPISASCPEPPIG CCCCCCCCCCCCCCC | 24.34 | 30059200 | |
| 461 | Phosphorylation | APAPISASCPEPPIG CCCCCCCCCCCCCCC | 24.34 | 26552605 | |
| 469 | Phosphorylation | CPEPPIGSAVPTSSA CCCCCCCCCCCCCCC | 27.15 | 26552605 | |
| 473 | O-linked_Glycosylation | PIGSAVPTSSASIPV CCCCCCCCCCCCCEE | 28.81 | 30059200 | |
| 473 | Phosphorylation | PIGSAVPTSSASIPV CCCCCCCCCCCCCEE | 28.81 | 26552605 | |
| 474 | Phosphorylation | IGSAVPTSSASIPVT CCCCCCCCCCCCEEE | 20.17 | 26552605 | |
| 475 | Phosphorylation | GSAVPTSSASIPVTS CCCCCCCCCCCEEEC | 28.63 | 26552605 | |
| 477 | Phosphorylation | AVPTSSASIPVTSSV CCCCCCCCCEEECCC | 29.40 | 26552605 | |
| 481 | Phosphorylation | SSASIPVTSSVSDPG CCCCCEEECCCCCCC | 15.21 | 26552605 | |
| 482 | Phosphorylation | SASIPVTSSVSDPGV CCCCEEECCCCCCCC | 29.04 | 29978859 | |
| 483 | Phosphorylation | ASIPVTSSVSDPGVG CCCEEECCCCCCCCC | 19.10 | 29978859 | |
| 485 | Phosphorylation | IPVTSSVSDPGVGSI CEEECCCCCCCCCCC | 39.78 | 25850435 | |
| 491 | Phosphorylation | VSDPGVGSISPASPK CCCCCCCCCCCCCCC | 19.93 | 25159151 | |
| 491 (in isoform 2) | Phosphorylation | - | 19.93 | - | |
| 491 (in isoform 3) | Phosphorylation | - | 19.93 | - | |
| 491 (in isoform 4) | Phosphorylation | - | 19.93 | - | |
| 491 (in isoform 8) | Phosphorylation | - | 19.93 | - | |
| 493 | Phosphorylation | DPGVGSISPASPKIS CCCCCCCCCCCCCCC | 18.99 | 25159151 | |
| 493 (in isoform 2) | Phosphorylation | - | 18.99 | - | |
| 493 (in isoform 3) | Phosphorylation | - | 18.99 | 27251275 | |
| 493 (in isoform 4) | Phosphorylation | - | 18.99 | - | |
| 493 (in isoform 8) | Phosphorylation | - | 18.99 | - | |
| 496 | Phosphorylation | VGSISPASPKISLAP CCCCCCCCCCCCCCC | 30.06 | 25159151 | |
| 496 (in isoform 2) | Phosphorylation | - | 30.06 | - | |
| 496 (in isoform 3) | Phosphorylation | - | 30.06 | 21406692 | |
| 496 (in isoform 4) | Phosphorylation | - | 30.06 | - | |
| 496 (in isoform 8) | Phosphorylation | - | 30.06 | - | |
| 500 | O-linked_Glycosylation | SPASPKISLAPTDVK CCCCCCCCCCCCCHH | 25.30 | 30059200 | |
| 500 | Phosphorylation | SPASPKISLAPTDVK CCCCCCCCCCCCCHH | 25.30 | 25159151 | |
| 500 (in isoform 3) | Phosphorylation | - | 25.30 | 27251275 | |
| 504 | Phosphorylation | PKISLAPTDVKELST CCCCCCCCCHHHHCC | 48.06 | 26074081 | |
| 507 | Ubiquitination | SLAPTDVKELSTKEP CCCCCCHHHHCCCCC | 56.60 | 21890473 | |
| 507 | Ubiquitination | SLAPTDVKELSTKEP CCCCCCHHHHCCCCC | 56.60 | 21890473 | |
| 507 | Acetylation | SLAPTDVKELSTKEP CCCCCCHHHHCCCCC | 56.60 | 25953088 | |
| 507 | Ubiquitination | SLAPTDVKELSTKEP CCCCCCHHHHCCCCC | 56.60 | 21890473 | |
| 507 (in isoform 1) | Ubiquitination | - | 56.60 | 21890473 | |
| 507 (in isoform 2) | Ubiquitination | - | 56.60 | 21890473 | |
| 507 (in isoform 3) | Ubiquitination | - | 56.60 | 21890473 | |
| 507 (in isoform 4) | Ubiquitination | - | 56.60 | 21890473 | |
| 507 (in isoform 5) | Ubiquitination | - | 56.60 | 21890473 | |
| 507 (in isoform 6) | Ubiquitination | - | 56.60 | 21890473 | |
| 510 | Phosphorylation | PTDVKELSTKEPGRT CCCHHHHCCCCCCCC | 38.23 | 21712546 | |
| 511 | Phosphorylation | TDVKELSTKEPGRTL CCHHHHCCCCCCCCC | 52.64 | 29083192 | |
| 512 | Acetylation | DVKELSTKEPGRTLE CHHHHCCCCCCCCCC | 59.54 | 25953088 | |
| 529 | Ubiquitination | ELARIAGKVPGLQNE HHHHHHCCCCCCCCH | 35.91 | 2190698 | |
| 529 (in isoform 1) | Ubiquitination | - | 35.91 | 21890473 | |
| 529 (in isoform 2) | Ubiquitination | - | 35.91 | 21890473 | |
| 529 (in isoform 3) | Ubiquitination | - | 35.91 | 21890473 | |
| 529 (in isoform 4) | Ubiquitination | - | 35.91 | 21890473 | |
| 529 (in isoform 5) | Ubiquitination | - | 35.91 | 21890473 | |
| 529 (in isoform 6) | Ubiquitination | - | 35.91 | 21890473 | |
| 538 | Acetylation | PGLQNEQKRFQLEEL CCCCCHHHHHCHHHH | 49.34 | 25953088 | |
| 538 | Ubiquitination | PGLQNEQKRFQLEEL CCCCCHHHHHCHHHH | 49.34 | - | |
| 539 | Methylation | GLQNEQKRFQLEELR CCCCHHHHHCHHHHH | 25.00 | - | |
| 546 | Methylation | RFQLEELRKFGAQFK HHCHHHHHHHCCCEE | 35.22 | - | |
| 547 | Ubiquitination | FQLEELRKFGAQFKL HCHHHHHHHCCCEEC | 61.85 | - | |
| 553 | Methylation | RKFGAQFKLQPSSSP HHHCCCEECCCCCCC | 33.85 | - | |
| 553 | Ubiquitination | RKFGAQFKLQPSSSP HHHCCCEECCCCCCC | 33.85 | - | |
| 557 | Phosphorylation | AQFKLQPSSSPENSL CCEECCCCCCCCCCC | 30.41 | 29255136 | |
| 557 (in isoform 2) | Phosphorylation | - | 30.41 | - | |
| 557 (in isoform 3) | Phosphorylation | - | 30.41 | 21406692 | |
| 557 (in isoform 4) | Phosphorylation | - | 30.41 | - | |
| 557 (in isoform 8) | Phosphorylation | - | 30.41 | - | |
| 558 | Phosphorylation | QFKLQPSSSPENSLD CEECCCCCCCCCCCC | 57.50 | 29255136 | |
| 558 (in isoform 2) | Phosphorylation | - | 57.50 | - | |
| 558 (in isoform 3) | Phosphorylation | - | 57.50 | 24719451 | |
| 558 (in isoform 4) | Phosphorylation | - | 57.50 | - | |
| 558 (in isoform 8) | Phosphorylation | - | 57.50 | - | |
| 559 | Phosphorylation | FKLQPSSSPENSLDP EECCCCCCCCCCCCC | 40.34 | 19664994 | |
| 559 (in isoform 2) | Phosphorylation | - | 40.34 | - | |
| 559 (in isoform 3) | Phosphorylation | - | 40.34 | 24719451 | |
| 559 (in isoform 4) | Phosphorylation | - | 40.34 | - | |
| 559 (in isoform 8) | Phosphorylation | - | 40.34 | - | |
| 563 | O-linked_Glycosylation | PSSSPENSLDPFPPR CCCCCCCCCCCCCCC | 32.27 | 30059200 | |
| 563 | Phosphorylation | PSSSPENSLDPFPPR CCCCCCCCCCCCCCC | 32.27 | 22167270 | |
| 563 (in isoform 2) | Phosphorylation | - | 32.27 | - | |
| 563 (in isoform 3) | Phosphorylation | - | 32.27 | - | |
| 563 (in isoform 4) | Phosphorylation | - | 32.27 | - | |
| 563 (in isoform 8) | Phosphorylation | - | 32.27 | - | |
| 573 | Sumoylation | PFPPRILKEEPKGKE CCCCCHHCCCCCCCC | 58.63 | - | |
| 573 | Sumoylation | PFPPRILKEEPKGKE CCCCCHHCCCCCCCC | 58.63 | 17000644 | |
| 573 | Ubiquitination | PFPPRILKEEPKGKE CCCCCHHCCCCCCCC | 58.63 | - | |
| 573 (in isoform 2) | Sumoylation | - | 58.63 | - | |
| 573 (in isoform 3) | Sumoylation | - | 58.63 | - | |
| 573 (in isoform 4) | Sumoylation | - | 58.63 | - | |
| 573 (in isoform 8) | Sumoylation | - | 58.63 | - | |
| 588 | Phosphorylation | KEVDGLLTSEPMGSP CCCCCCCCCCCCCCC | 35.77 | 29255136 | |
| 588 (in isoform 2) | Phosphorylation | - | 35.77 | - | |
| 588 (in isoform 3) | Phosphorylation | - | 35.77 | - | |
| 588 (in isoform 4) | Phosphorylation | - | 35.77 | - | |
| 588 (in isoform 8) | Phosphorylation | - | 35.77 | - | |
| 589 | Phosphorylation | EVDGLLTSEPMGSPV CCCCCCCCCCCCCCC | 39.41 | 29255136 | |
| 589 (in isoform 2) | Phosphorylation | - | 39.41 | - | |
| 589 (in isoform 3) | Phosphorylation | - | 39.41 | 21406692 | |
| 589 (in isoform 4) | Phosphorylation | - | 39.41 | - | |
| 589 (in isoform 8) | Phosphorylation | - | 39.41 | - | |
| 592 | Sulfoxidation | GLLTSEPMGSPVSSK CCCCCCCCCCCCCCC | 7.93 | 21406390 | |
| 594 | Phosphorylation | LTSEPMGSPVSSKTE CCCCCCCCCCCCCCC | 18.84 | 19664994 | |
| 594 (in isoform 2) | Phosphorylation | - | 18.84 | - | |
| 594 (in isoform 3) | Phosphorylation | - | 18.84 | 21406692 | |
| 594 (in isoform 4) | Phosphorylation | - | 18.84 | - | |
| 594 (in isoform 8) | Phosphorylation | - | 18.84 | - | |
| 597 | Phosphorylation | EPMGSPVSSKTESVS CCCCCCCCCCCCCCC | 29.51 | 29255136 | |
| 597 (in isoform 2) | Phosphorylation | - | 29.51 | - | |
| 597 (in isoform 3) | Phosphorylation | - | 29.51 | 21406692 | |
| 597 (in isoform 4) | Phosphorylation | - | 29.51 | - | |
| 597 (in isoform 8) | Phosphorylation | - | 29.51 | - | |
| 598 | Phosphorylation | PMGSPVSSKTESVSD CCCCCCCCCCCCCCC | 43.78 | 29255136 | |
| 598 (in isoform 2) | Phosphorylation | - | 43.78 | - | |
| 598 (in isoform 3) | Phosphorylation | - | 43.78 | 21406692 | |
| 598 (in isoform 4) | Phosphorylation | - | 43.78 | - | |
| 598 (in isoform 8) | Phosphorylation | - | 43.78 | - | |
| 600 | Phosphorylation | GSPVSSKTESVSDKE CCCCCCCCCCCCCCC | 35.13 | 30278072 | |
| 600 (in isoform 3) | Phosphorylation | - | 35.13 | 27251275 | |
| 602 | Phosphorylation | PVSSKTESVSDKEDK CCCCCCCCCCCCCCC | 31.95 | 23927012 | |
| 604 | Phosphorylation | SSKTESVSDKEDKPP CCCCCCCCCCCCCCC | 52.85 | 23927012 | |
| 604 (in isoform 3) | Phosphorylation | - | 52.85 | 27251275 | |
| 615 | Phosphorylation | DKPPLAPSGGTEGPE CCCCCCCCCCCCCCC | 44.22 | 23401153 | |
| 615 (in isoform 2) | Phosphorylation | - | 44.22 | - | |
| 615 (in isoform 3) | Phosphorylation | - | 44.22 | - | |
| 615 (in isoform 4) | Phosphorylation | - | 44.22 | - | |
| 615 (in isoform 8) | Phosphorylation | - | 44.22 | - | |
| 618 | Phosphorylation | PLAPSGGTEGPEQPP CCCCCCCCCCCCCCC | 41.09 | 30278072 | |
| 630 | Phosphorylation | QPPPPCPSQTGSPPV CCCCCCCCCCCCCCC | 47.28 | 23401153 | |
| 630 (in isoform 3) | Phosphorylation | - | 47.28 | 21406692 | |
| 632 | Phosphorylation | PPPCPSQTGSPPVGL CCCCCCCCCCCCCEE | 43.92 | 29255136 | |
| 632 (in isoform 2) | Phosphorylation | - | 43.92 | - | |
| 632 (in isoform 3) | Phosphorylation | - | 43.92 | 21406692 | |
| 632 (in isoform 4) | Phosphorylation | - | 43.92 | - | |
| 632 (in isoform 8) | Phosphorylation | - | 43.92 | - | |
| 634 | Phosphorylation | PCPSQTGSPPVGLIK CCCCCCCCCCCEEEC | 29.44 | 29255136 | |
| 634 (in isoform 2) | Phosphorylation | - | 29.44 | - | |
| 634 (in isoform 3) | Phosphorylation | - | 29.44 | 21406692 | |
| 634 (in isoform 4) | Phosphorylation | - | 29.44 | - | |
| 634 (in isoform 8) | Phosphorylation | - | 29.44 | - | |
| 641 | Sumoylation | SPPVGLIKGEDKDEG CCCCEEECCCCCCCC | 62.38 | - | |
| 641 | Sumoylation | SPPVGLIKGEDKDEG CCCCEEECCCCCCCC | 62.38 | 17000644 | |
| 641 (in isoform 2) | Sumoylation | - | 62.38 | - | |
| 641 (in isoform 3) | Sumoylation | - | 62.38 | - | |
| 641 (in isoform 4) | Sumoylation | - | 62.38 | - | |
| 641 (in isoform 8) | Sumoylation | - | 62.38 | - | |
| 656 | Ubiquitination | PVAEQVKKSTLNPNA CHHHHHHHHHCCCCC | 50.22 | - | |
| 658 | Phosphorylation | AEQVKKSTLNPNAKE HHHHHHHHCCCCCHH | 39.16 | - | |
| 669 | Phosphorylation | NAKEFNPTKPLLSVN CCHHCCCCCCCEEEC | 46.53 | 28122231 | |
| 670 | Acetylation | AKEFNPTKPLLSVNK CHHCCCCCCCEEECC | 34.62 | 23954790 | |
| 670 | Ubiquitination | AKEFNPTKPLLSVNK CHHCCCCCCCEEECC | 34.62 | - | |
| 674 | Phosphorylation | NPTKPLLSVNKSTST CCCCCCEEECCCCCC | 31.18 | 28555341 | |
| 678 | O-linked_Glycosylation | PLLSVNKSTSTPTSP CCEEECCCCCCCCCC | 23.53 | 32574038 | |
| 678 | O-linked_Glycosylation | PLLSVNKSTSTPTSP CCEEECCCCCCCCCC | 23.53 | 20068230 | |
| 678 | Phosphorylation | PLLSVNKSTSTPTSP CCEEECCCCCCCCCC | 23.53 | 30266825 | |
| 678 (in isoform 2) | O-linked_Glycosylation | - | 23.53 | - | |
| 678 (in isoform 3) | O-linked_Glycosylation | - | 23.53 | - | |
| 678 (in isoform 3) | Phosphorylation | - | 23.53 | 27251275 | |
| 678 (in isoform 4) | O-linked_Glycosylation | - | 23.53 | - | |
| 678 (in isoform 8) | O-linked_Glycosylation | - | 23.53 | - | |
| 679 | Phosphorylation | LLSVNKSTSTPTSPG CEEECCCCCCCCCCC | 37.92 | 30266825 | |
| 679 (in isoform 3) | Phosphorylation | - | 37.92 | 24719451 | |
| 680 | Phosphorylation | LSVNKSTSTPTSPGP EEECCCCCCCCCCCC | 39.21 | 29255136 | |
| 680 (in isoform 2) | Phosphorylation | - | 39.21 | - | |
| 680 (in isoform 3) | Phosphorylation | - | 39.21 | 27251275 | |
| 680 (in isoform 4) | Phosphorylation | - | 39.21 | - | |
| 680 (in isoform 8) | Phosphorylation | - | 39.21 | - | |
| 681 | O-linked_Glycosylation | SVNKSTSTPTSPGPR EECCCCCCCCCCCCC | 30.58 | 30059200 | |
| 681 | Phosphorylation | SVNKSTSTPTSPGPR EECCCCCCCCCCCCC | 30.58 | 30266825 | |
| 681 (in isoform 2) | Phosphorylation | - | 30.58 | - | |
| 681 (in isoform 3) | Phosphorylation | - | 30.58 | - | |
| 681 (in isoform 4) | Phosphorylation | - | 30.58 | - | |
| 681 (in isoform 8) | Phosphorylation | - | 30.58 | - | |
| 683 | O-linked_Glycosylation | NKSTSTPTSPGPRTH CCCCCCCCCCCCCCC | 47.87 | 30059200 | |
| 683 | Phosphorylation | NKSTSTPTSPGPRTH CCCCCCCCCCCCCCC | 47.87 | 29255136 | |
| 683 (in isoform 2) | Phosphorylation | - | 47.87 | - | |
| 683 (in isoform 3) | Phosphorylation | - | 47.87 | 24719451 | |
| 683 (in isoform 4) | Phosphorylation | - | 47.87 | - | |
| 683 (in isoform 8) | Phosphorylation | - | 47.87 | - | |
| 684 | O-linked_Glycosylation | KSTSTPTSPGPRTHS CCCCCCCCCCCCCCC | 29.12 | 32574038 | |
| 684 | O-linked_Glycosylation | KSTSTPTSPGPRTHS CCCCCCCCCCCCCCC | 29.12 | 19691289 | |
| 684 | Phosphorylation | KSTSTPTSPGPRTHS CCCCCCCCCCCCCCC | 29.12 | 29255136 | |
| 684 (in isoform 2) | O-linked_Glycosylation | - | 29.12 | - | |
| 684 (in isoform 2) | Phosphorylation | - | 29.12 | - | |
| 684 (in isoform 3) | O-linked_Glycosylation | - | 29.12 | - | |
| 684 (in isoform 3) | Phosphorylation | - | 29.12 | 27251275 | |
| 684 (in isoform 4) | O-linked_Glycosylation | - | 29.12 | - | |
| 684 (in isoform 4) | Phosphorylation | - | 29.12 | - | |
| 684 (in isoform 8) | O-linked_Glycosylation | - | 29.12 | - | |
| 684 (in isoform 8) | Phosphorylation | - | 29.12 | - | |
| 688 | Methylation | TPTSPGPRTHSTPSI CCCCCCCCCCCCCCC | 51.49 | - | |
| 689 | Phosphorylation | PTSPGPRTHSTPSIP CCCCCCCCCCCCCCC | 24.26 | 26074081 | |
| 691 | Phosphorylation | SPGPRTHSTPSIPVL CCCCCCCCCCCCCEE | 41.21 | 26074081 | |
| 692 | Phosphorylation | PGPRTHSTPSIPVLT CCCCCCCCCCCCEEC | 17.28 | 26074081 | |
| 694 | Phosphorylation | PRTHSTPSIPVLTAG CCCCCCCCCCEECCC | 39.34 | 26074081 | |
| 699 | Phosphorylation | TPSIPVLTAGQSGLY CCCCCEECCCCCCCC | 29.04 | 26074081 | |
| 706 | Phosphorylation | TAGQSGLYSPQYISY CCCCCCCCCHHHHHC | 23.10 | - | |
| 744 | Phosphorylation | VPGQQGKYRGAKGSL CCCCCCCCCCCCCCC | 22.54 | 18698806 | |
| 958 (in isoform 6) | Phosphorylation | - | 28.77 | 20068231 | |
| 1017 | O-linked_Glycosylation | VPALSASTPSPYPYI CCCCCCCCCCCCCCC | 27.74 | OGP | |
| 1050 | Phosphorylation | DDRIREFSLAGGIWH CHHHHEEEEECCEEC | 16.74 | 20068231 | |
| 1084 (in isoform 3) | Phosphorylation | - | 28348404 | ||
| 1086 (in isoform 3) | Phosphorylation | - | 28348404 | ||
| 1090 (in isoform 3) | Phosphorylation | - | 28348404 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 744 | Y | Phosphorylation | Kinase | SRC | P12931 | PSP |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ATX2L_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ATX2L_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ECHA_HUMAN | HADHA | physical | 21988832 | |
| LSM12_HUMAN | LSM12 | physical | 26344197 | |
| PABP1_HUMAN | PABPC1 | physical | 26344197 | |
| PABP4_HUMAN | PABPC4 | physical | 26344197 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Acetylation | |
| Reference | PubMed |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-111; SER-496; SER-559; SER-594; SER-597;SER-598 AND SER-684, AND MASS SPECTROMETRY. | |
| "Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-348, AND MASS SPECTROMETRY. | |
| Methylation | |
| Reference | PubMed |
| "Identifying and quantifying in vivo methylation sites by heavy methylSILAC."; Ong S.E., Mittler G., Mann M.; Nat. Methods 1:119-126(2004). Cited for: METHYLATION [LARGE SCALE ANALYSIS] AT ARG-361, AND MASS SPECTROMETRY. | |
| Phosphorylation | |
| Reference | PubMed |
| "Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111; TYR-118; SER-238;SER-558; SER-559 AND SER-594, AND MASS SPECTROMETRY. | |
| "Large-scale proteomics analysis of the human kinome."; Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.; Mol. Cell. Proteomics 8:1751-1764(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111; SER-339; SER-557AND SER-594, AND MASS SPECTROMETRY. | |
| "Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-111; SER-496; SER-559; SER-594; SER-597;SER-598 AND SER-684, AND MASS SPECTROMETRY. | |
| "A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111; SER-557; SER-559;SER-594; SER-634 AND SER-684, AND MASS SPECTROMETRY. | |
| "Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-339 AND SER-594, ANDMASS SPECTROMETRY. | |
| "Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111; SER-449; SER-559;SER-630 AND SER-634, AND MASS SPECTROMETRY. | |
| "Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-594, AND MASSSPECTROMETRY. | |
| "Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry."; Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.; Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111; SER-335; SER-339;SER-341; SER-557; SER-558; SER-559; SER-563; SER-589; SER-594; SER-597AND SER-598, AND MASS SPECTROMETRY. | |
| "Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-390; SER-391; SER-559AND SER-684, AND MASS SPECTROMETRY. | |
| "A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111 AND SER-594, ANDMASS SPECTROMETRY. | |
| "Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-409; SER-493; SER-496AND SER-594, AND MASS SPECTROMETRY. | |
| "Large-scale characterization of HeLa cell nuclear phosphoproteins."; Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-111; SER-559 ANDSER-594, AND MASS SPECTROMETRY. | |
| "Robust phosphoproteomic profiling of tyrosine phosphorylation sitesfrom human T cells using immobilized metal affinity chromatography andtandem mass spectrometry."; Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M.,Peters E.C.; Anal. Chem. 76:2763-2772(2004). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-264; TYR-309; TYR-349AND SER-391, AND MASS SPECTROMETRY. | |
