GTF2I_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GTF2I_HUMAN
• UniProt AC: P78347
• Protein Name: General transcription factor II-I
• Gene Name: GTF2I
• Organism: Homo sapiens (Human).
• Sequence Length: 998
• Subcellular Localization: Cytoplasm . Nucleus . Colocalizes with BTK in the cytoplasm.
• Protein Description: Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation..
• Protein Sequence: MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAQVAMSTL ------CCCCCCCCC	24.70	22223895
7	Phosphorylation	-MAQVAMSTLPVEDE -CCCCCCCCCCCCCC	19.63	28355574
8	Phosphorylation	MAQVAMSTLPVEDEE CCCCCCCCCCCCCCC	23.23	25106551
16	Phosphorylation	LPVEDEESSESRMVV CCCCCCCCCHHHHHH	37.04	23401153
17	Phosphorylation	PVEDEESSESRMVVT CCCCCCCCHHHHHHH	42.76	29255136
19	Phosphorylation	EDEESSESRMVVTFL CCCCCCHHHHHHHHH	27.85	29255136
24	Phosphorylation	SESRMVVTFLMSALE CHHHHHHHHHHHHHH	10.31	23879269
35	Sumoylation	SALESMCKELAKSKA HHHHHHHHHHHHCCC	47.31	28112733
70	Ubiquitination	RAFVNTRKDFQKDFV CEEECCCHHHHHHHH	61.94	-
74	Acetylation	NTRKDFQKDFVKYCV CCCHHHHHHHHHHHH	53.80	26051181
74	Ubiquitination	NTRKDFQKDFVKYCV CCCHHHHHHHHHHHH	53.80	21890473
74 (in isoform 1)	Ubiquitination	-	53.80	21890473
74 (in isoform 2)	Ubiquitination	-	53.80	21890473
74 (in isoform 3)	Ubiquitination	-	53.80	21890473
74 (in isoform 4)	Ubiquitination	-	53.80	21890473
74	Ubiquitination	NTRKDFQKDFVKYCV CCCHHHHHHHHHHHH	53.80	21890473
78	Acetylation	DFQKDFVKYCVEEEE HHHHHHHHHHHHHHH	32.69	26051181
78	Ubiquitination	DFQKDFVKYCVEEEE HHHHHHHHHHHHHHH	32.69	-
79	Phosphorylation	FQKDFVKYCVEEEEK HHHHHHHHHHHHHHH	9.09	28102081
80	Glutathionylation	QKDFVKYCVEEEEKA HHHHHHHHHHHHHHH	2.29	22555962
86	Sumoylation	YCVEEEEKAAEMHKM HHHHHHHHHHHHHHC	57.06	-
86	Acetylation	YCVEEEEKAAEMHKM HHHHHHHHHHHHHHC	57.06	26051181
86	Sumoylation	YCVEEEEKAAEMHKM HHHHHHHHHHHHHHC	57.06	28112733
92	Sumoylation	EKAAEMHKMKSTTQA HHHHHHHHCCCCHHH	46.87	28112733
94	Sumoylation	AAEMHKMKSTTQANR HHHHHHCCCCHHHHC	49.83	-
94	Sumoylation	AAEMHKMKSTTQANR HHHHHHCCCCHHHHC	49.83	28112733
95	Phosphorylation	AEMHKMKSTTQANRM HHHHHCCCCHHHHCC	32.94	30243723
96	Phosphorylation	EMHKMKSTTQANRMS HHHHCCCCHHHHCCC	19.87	28450419
97	Phosphorylation	MHKMKSTTQANRMSV HHHCCCCHHHHCCCC	32.54	30243723
101	Methylation	KSTTQANRMSVDAVE CCCHHHHCCCCCEEE	23.05	-
102	Sulfoxidation	STTQANRMSVDAVEI CCHHHHCCCCCEEEH	4.61	21406390
103	Phosphorylation	TTQANRMSVDAVEIE CHHHHCCCCCEEEHH	17.38	19664994
111	Phosphorylation	VDAVEIETLRKTVED CCEEEHHHHHHHHHH	37.21	29978859
126	Acetylation	YFCFCYGKALGKSTV HHHHHHHHHCCCCCE	17.60	26051181
130	Sumoylation	CYGKALGKSTVVPVP HHHHHCCCCCEEECC	43.75	-
130	2-Hydroxyisobutyrylation	CYGKALGKSTVVPVP HHHHHCCCCCEEECC	43.75	-
130	Acetylation	CYGKALGKSTVVPVP HHHHHCCCCCEEECC	43.75	-
130	Sumoylation	CYGKALGKSTVVPVP HHHHHCCCCCEEECC	43.75	28112733
130	Ubiquitination	CYGKALGKSTVVPVP HHHHHCCCCCEEECC	43.75	-
140	Sumoylation	VVPVPYEKMLRDQSA EEECCHHHHCCCCCE	37.07	-
140	Acetylation	VVPVPYEKMLRDQSA EEECCHHHHCCCCCE	37.07	26051181
140	Sumoylation	VVPVPYEKMLRDQSA EEECCHHHHCCCCCE	37.07	28112733
140	Ubiquitination	VVPVPYEKMLRDQSA EEECCHHHHCCCCCE	37.07	21890473
140 (in isoform 1)	Ubiquitination	-	37.07	21890473
140 (in isoform 2)	Ubiquitination	-	37.07	21890473
140 (in isoform 3)	Ubiquitination	-	37.07	21890473
140 (in isoform 4)	Ubiquitination	-	37.07	21890473
140	Ubiquitination	VVPVPYEKMLRDQSA EEECCHHHHCCCCCE	37.07	21890473
143	Methylation	VPYEKMLRDQSAVVV CCHHHHCCCCCEEEE	36.10	-
146	Phosphorylation	EKMLRDQSAVVVQGL HHHCCCCCEEEECCC	27.59	28387310
160	Acetylation	LPEGVAFKHPENYDL CCCCCCCCCCCCCCH	48.81	26051181
160	Ubiquitination	LPEGVAFKHPENYDL CCCCCCCCCCCCCCH	48.81	21890473
160 (in isoform 1)	Ubiquitination	-	48.81	21890473
160 (in isoform 2)	Ubiquitination	-	48.81	21890473
160 (in isoform 3)	Ubiquitination	-	48.81	21890473
160 (in isoform 4)	Ubiquitination	-	48.81	21890473
160	Ubiquitination	LPEGVAFKHPENYDL CCCCCCCCCCCCCCH	48.81	21890473
171	Acetylation	NYDLATLKWILENKA CCCHHHHHHHHHCCC	28.03	26051181
171	Ubiquitination	NYDLATLKWILENKA CCCHHHHHHHHHCCC	28.03	-
177	Sumoylation	LKWILENKAGISFII HHHHHHCCCCEEEEE	38.32	-
181	Phosphorylation	LENKAGISFIIKRPF HHCCCCEEEEEECCC	14.96	27499020
185	Acetylation	AGISFIIKRPFLEPK CCEEEEEECCCCCCC	49.56	26051181
185	Sumoylation	AGISFIIKRPFLEPK CCEEEEEECCCCCCC	49.56	28112733
192	2-Hydroxyisobutyrylation	KRPFLEPKKHVGGRV ECCCCCCCCCCCCEE	46.25	-
200	Sulfoxidation	KHVGGRVMVTDADRS CCCCCEEEEECCCCC	2.30	21406390
202	Phosphorylation	VGGRVMVTDADRSIL CCCEEEEECCCCCCC	13.84	22617229
206	Methylation	VMVTDADRSILSPGG EEEECCCCCCCCCCC	27.58	-
207	Phosphorylation	MVTDADRSILSPGGS EEECCCCCCCCCCCC	28.55	23927012
210	Phosphorylation	DADRSILSPGGSCGP CCCCCCCCCCCCCCC	21.59	19664994
214	Phosphorylation	SILSPGGSCGPIKVK CCCCCCCCCCCEEEE	23.09	23401153
215	Glutathionylation	ILSPGGSCGPIKVKT CCCCCCCCCCEEEEC	9.45	22555962
219	Acetylation	GGSCGPIKVKTEPTE CCCCCCEEEECCCCC	40.59	25953088
219	Methylation	GGSCGPIKVKTEPTE CCCCCCEEEECCCCC	40.59	23583077
219	Sumoylation	GGSCGPIKVKTEPTE CCCCCCEEEECCCCC	40.59	28112733
219	Ubiquitination	GGSCGPIKVKTEPTE CCCCCCEEEECCCCC	40.59	-
221	Sumoylation	SCGPIKVKTEPTEDS CCCCEEEECCCCCCC	42.01	-
221	Sumoylation	SCGPIKVKTEPTEDS CCCCEEEECCCCCCC	42.01	25114211
222	Phosphorylation	CGPIKVKTEPTEDSG CCCEEEECCCCCCCC	50.62	20873877
225	Phosphorylation	IKVKTEPTEDSGISL EEEECCCCCCCCCEE	46.31	20873877
228	Phosphorylation	KTEPTEDSGISLEMA ECCCCCCCCCEEEEE	31.62	20873877
231	Phosphorylation	PTEDSGISLEMAAVT CCCCCCCEEEEEEEE	23.08	20873877
238	Phosphorylation	SLEMAAVTVKEESED EEEEEEEEEECCCCC	22.57	21406692
240	Sumoylation	EMAAVTVKEESEDPD EEEEEEEECCCCCCC	46.53	-
240	Sumoylation	EMAAVTVKEESEDPD EEEEEEEECCCCCCC	46.53	-
248	Phosphorylation	EESEDPDYYQYNIQA CCCCCCCCEEEEECC	9.61	16738337
248 (in isoform 2)	Phosphorylation	-	9.61	9012831
248 (in isoform 3)	Phosphorylation	-	9.61	9012831
248 (in isoform 5)	Phosphorylation	-	9.61	9012831
249	Phosphorylation	ESEDPDYYQYNIQAG CCCCCCCEEEEECCC	16.35	9837922
249 (in isoform 2)	Phosphorylation	-	16.35	-
249 (in isoform 3)	Phosphorylation	-	16.35	-
249 (in isoform 5)	Phosphorylation	-	16.35	-
251 (in isoform 2)	Phosphorylation	-	9.71	-
251 (in isoform 3)	Phosphorylation	-	9.71	-
251 (in isoform 5)	Phosphorylation	-	9.71	-
256 (in isoform 2)	Phosphorylation	-	15.19	24144214
259 (in isoform 2)	Phosphorylation	-	60.43	24144214
260 (in isoform 2)	Phosphorylation	-	41.66	24144214
266 (in isoform 2)	Phosphorylation	-	53.40	24144214
270	Phosphorylation	VDEKQPLSKPLQGSH CCCCCCCCCCCCCCC	38.62	24719451
276 (in isoform 4)	Phosphorylation	-	12.69	27732954
277 (in isoform 2)	Phosphorylation	-	31.50	28387310
278 (in isoform 2)	Phosphorylation	-	34.42	28387310
279 (in isoform 4)	Phosphorylation	-	25.35	27732954
280 (in isoform 4)	Phosphorylation	-	45.20	27732954
281 (in isoform 2)	Phosphorylation	-	69.88	28387310
286 (in isoform 4)	Phosphorylation	-	26.44	27732954
297 (in isoform 4)	Phosphorylation	-	39.26	27732954
298 (in isoform 4)	Phosphorylation	-	33.28	25159151
301 (in isoform 4)	Phosphorylation	-	53.03	27732954
312	Phosphorylation	EDPEVEVTIEDDDYS CCCCEEEEEECCCCC	12.73	26074081
312 (in isoform 2)	Ubiquitination	-	12.73	21890473
318	Phosphorylation	VTIEDDDYSPPSKRP EEEECCCCCCCCCCC	30.03	10373551
319	Phosphorylation	TIEDDDYSPPSKRPK EEECCCCCCCCCCCC	37.01	26074081
322	Phosphorylation	DDDYSPPSKRPKANE CCCCCCCCCCCCCCC	44.68	26074081
326	Sumoylation	SPPSKRPKANELPQP CCCCCCCCCCCCCCC	68.80	-
326	Sumoylation	SPPSKRPKANELPQP CCCCCCCCCCCCCCC	68.80	28112733
332 (in isoform 4)	Ubiquitination	-	68.50	21890473
333 (in isoform 3)	Ubiquitination	-	29.89	21890473
343	Sumoylation	PEPANAGKRKVREFN CCCCCCCCCCCCCCC	46.78	-
343	Acetylation	PEPANAGKRKVREFN CCCCCCCCCCCCCCC	46.78	25953088
343	Methylation	PEPANAGKRKVREFN CCCCCCCCCCCCCCC	46.78	-
343	Sumoylation	PEPANAGKRKVREFN CCCCCCCCCCCCCCC	46.78	28112733
353	Sumoylation	VREFNFEKWNARITD CCCCCHHHHHHHHHH	41.43	-
353	Acetylation	VREFNFEKWNARITD CCCCCHHHHHHHHHH	41.43	26822725
353	Sumoylation	VREFNFEKWNARITD CCCCCHHHHHHHHHH	41.43	28112733
353	Ubiquitination	VREFNFEKWNARITD CCCCCHHHHHHHHHH	41.43	21890473
353 (in isoform 1)	Ubiquitination	-	41.43	21890473
359	Phosphorylation	EKWNARITDLRKQVE HHHHHHHHHHHHHHH	24.35	23090842
363	Sumoylation	ARITDLRKQVEELFE HHHHHHHHHHHHHHH	67.02	-
363	Ubiquitination	ARITDLRKQVEELFE HHHHHHHHHHHHHHH	67.02	-
372	Sumoylation	VEELFERKYAQAIKA HHHHHHHHHHHHHHH	37.43	-
372	Sumoylation	VEELFERKYAQAIKA HHHHHHHHHHHHHHH	37.43	-
372	Ubiquitination	VEELFERKYAQAIKA HHHHHHHHHHHHHHH	37.43	-
378	Sumoylation	RKYAQAIKAKGPVTI HHHHHHHHHCCCEEC	47.24	-
378	Sumoylation	RKYAQAIKAKGPVTI HHHHHHHHHCCCEEC	47.24	-
378	Ubiquitination	RKYAQAIKAKGPVTI HHHHHHHHHCCCEEC	47.24	-
380	Sumoylation	YAQAIKAKGPVTIPY HHHHHHHCCCEECCC	59.76	28112733
380	Ubiquitination	YAQAIKAKGPVTIPY HHHHHHHCCCEECCC	59.76	-
392	Phosphorylation	IPYPLFQSHVEDLYV CCCCHHHHHHHHHHC	23.36	12082086
398	Phosphorylation	QSHVEDLYVEGLPEG HHHHHHHHCCCCCCC	14.58	17360941
412	Phosphorylation	GIPFRRPSTYGIPRL CCCCCCCHHCCCCHH	32.23	23911959
413	Phosphorylation	IPFRRPSTYGIPRLE CCCCCCHHCCCCHHH	28.57	27794612
414	Phosphorylation	PFRRPSTYGIPRLER CCCCCHHCCCCHHHH	19.86	28857561
435	Sumoylation	RIRFVIKKHELLNST HHHHHHHHHHHHHCC	31.05	-
435	Acetylation	RIRFVIKKHELLNST HHHHHHHHHHHHHCC	31.05	27452117
435	Sumoylation	RIRFVIKKHELLNST HHHHHHHHHHHHHCC	31.05	28112733
435	Ubiquitination	RIRFVIKKHELLNST HHHHHHHHHHHHHCC	31.05	-
435 (in isoform 2)	Ubiquitination	-	31.05	21890473
442	Phosphorylation	KHELLNSTREDLQLD HHHHHHCCCHHHCCC	36.68	28555341
447 (in isoform 2)	Ubiquitination	-	61.00	21890473
450	Sumoylation	REDLQLDKPASGVKE CHHHCCCCCCCCCCH	51.59	-
450	Acetylation	REDLQLDKPASGVKE CHHHCCCCCCCCCCH	51.59	23954790
450	Sumoylation	REDLQLDKPASGVKE CHHHCCCCCCCCCCH	51.59	28112733
450	Ubiquitination	REDLQLDKPASGVKE CHHHCCCCCCCCCCH	51.59	-
453	Phosphorylation	LQLDKPASGVKEEWY HCCCCCCCCCCHHHH	53.28	25159151
453 (in isoform 2)	Ubiquitination	-	53.28	21890473
455 (in isoform 4)	Ubiquitination	-	6.99	21890473
456	Sumoylation	DKPASGVKEEWYARI CCCCCCCCHHHHHHH	54.14	-
456	2-Hydroxyisobutyrylation	DKPASGVKEEWYARI CCCCCCCCHHHHHHH	54.14	-
456	Acetylation	DKPASGVKEEWYARI CCCCCCCCHHHHHHH	54.14	26051181
456	Methylation	DKPASGVKEEWYARI CCCCCCCCHHHHHHH	54.14	24129315
456	Sumoylation	DKPASGVKEEWYARI CCCCCCCCHHHHHHH	54.14	28112733
456	Ubiquitination	DKPASGVKEEWYARI CCCCCCCCHHHHHHH	54.14	-
456 (in isoform 3)	Ubiquitination	-	54.14	21890473
460	Phosphorylation	SGVKEEWYARITKLR CCCCHHHHHHHHHHH	6.84	17360941
467 (in isoform 4)	Ubiquitination	-	26.95	21890473
468	2-Hydroxyisobutyrylation	ARITKLRKMVDQLFC HHHHHHHHHHHHHHH	54.43	-
468	Acetylation	ARITKLRKMVDQLFC HHHHHHHHHHHHHHH	54.43	26051181
468 (in isoform 3)	Ubiquitination	-	54.43	21890473
469	Sulfoxidation	RITKLRKMVDQLFCK HHHHHHHHHHHHHHH	3.04	21406390
473 (in isoform 4)	Ubiquitination	-	4.75	21890473
474 (in isoform 3)	Ubiquitination	-	4.82	21890473
475	S-nitrosocysteine	KMVDQLFCKKFAEAL HHHHHHHHHHHHHHH	6.78	-
475	S-nitrosylation	KMVDQLFCKKFAEAL HHHHHHHHHHHHHHH	6.78	22178444
476	Ubiquitination	MVDQLFCKKFAEALG HHHHHHHHHHHHHHC	43.52	21906983
476 (in isoform 1)	Ubiquitination	-	43.52	21890473
477	Sumoylation	VDQLFCKKFAEALGS HHHHHHHHHHHHHCC	51.49	-
477	Acetylation	VDQLFCKKFAEALGS HHHHHHHHHHHHHCC	51.49	25953088
477	Sumoylation	VDQLFCKKFAEALGS HHHHHHHHHHHHHCC	51.49	-
477	Ubiquitination	VDQLFCKKFAEALGS HHHHHHHHHHHHHCC	51.49	-
488	Sumoylation	ALGSTEAKAVPYQKF HHCCCCCCCCCHHHH	43.62	-
488	Acetylation	ALGSTEAKAVPYQKF HHCCCCCCCCCHHHH	43.62	26051181
488	Sumoylation	ALGSTEAKAVPYQKF HHCCCCCCCCCHHHH	43.62	28112733
488	Ubiquitination	ALGSTEAKAVPYQKF HHCCCCCCCCCHHHH	43.62	21906983
488 (in isoform 1)	Ubiquitination	-	43.62	21890473
494	Sumoylation	AKAVPYQKFEAHPND CCCCCHHHHCCCCCC	39.05	-
494	Acetylation	AKAVPYQKFEAHPND CCCCCHHHHCCCCCC	39.05	25953088
494	Sumoylation	AKAVPYQKFEAHPND CCCCCHHHHCCCCCC	39.05	28112733
494	Ubiquitination	AKAVPYQKFEAHPND CCCCCHHHHCCCCCC	39.05	21890473
494 (in isoform 1)	Ubiquitination	-	39.05	21890473
498 (in isoform 2)	Ubiquitination	-	17.94	21890473
503	Phosphorylation	EAHPNDLYVEGLPEN CCCCCCCEECCCCCC	10.18	21082442
515	Phosphorylation	PENIPFRSPSWYGIP CCCCCCCCCCCCCCC	24.54	25159151
517	Phosphorylation	NIPFRSPSWYGIPRL CCCCCCCCCCCCCHH	33.89	25159151
518 (in isoform 4)	Ubiquitination	-	9.96	21890473
519	Phosphorylation	PFRSPSWYGIPRLEK CCCCCCCCCCCHHHH	14.98	22115753
519 (in isoform 3)	Ubiquitination	-	14.98	21890473
520 (in isoform 2)	Ubiquitination	-	19.71	21890473
526	Sumoylation	YGIPRLEKIIQVGNR CCCCHHHHHHHHCCE	50.10	-
526	2-Hydroxyisobutyrylation	YGIPRLEKIIQVGNR CCCCHHHHHHHHCCE	50.10	-
526	Acetylation	YGIPRLEKIIQVGNR CCCCHHHHHHHHCCE	50.10	26051181
526	Malonylation	YGIPRLEKIIQVGNR CCCCHHHHHHHHCCE	50.10	26320211
526	Sumoylation	YGIPRLEKIIQVGNR CCCCHHHHHHHHCCE	50.10	28112733
526	Ubiquitination	YGIPRLEKIIQVGNR CCCCHHHHHHHHCCE	50.10	-
539	Ubiquitination	NRIKFVIKRPELLTH CEEEEEEECHHHHCC	57.51	21890473
539 (in isoform 1)	Ubiquitination	-	57.51	21890473
540 (in isoform 4)	Ubiquitination	-	20.85	21890473
541 (in isoform 3)	Ubiquitination	-	31.42	21890473
545	Phosphorylation	IKRPELLTHSTTEVT EECHHHHCCCCCEEC	26.80	23312004
547	Phosphorylation	RPELLTHSTTEVTQP CHHHHCCCCCEECCC	31.61	28857561
548	Phosphorylation	PELLTHSTTEVTQPR HHHHCCCCCEECCCC	21.26	28555341
549	Phosphorylation	ELLTHSTTEVTQPRT HHHCCCCCEECCCCC	31.32	23312004
552	Phosphorylation	THSTTEVTQPRTNTP CCCCCEECCCCCCCC	26.99	28555341
556	Phosphorylation	TEVTQPRTNTPVKED CEECCCCCCCCCCCC	50.56	22167270
558	Phosphorylation	VTQPRTNTPVKEDWN ECCCCCCCCCCCCCH	28.92	22167270
561	Sumoylation	PRTNTPVKEDWNVRI CCCCCCCCCCCHHHH	51.68	-
561	Acetylation	PRTNTPVKEDWNVRI CCCCCCCCCCCHHHH	51.68	23954790
561	Sumoylation	PRTNTPVKEDWNVRI CCCCCCCCCCCHHHH	51.68	28112733
561	Ubiquitination	PRTNTPVKEDWNVRI CCCCCCCCCCCHHHH	51.68	21890473
561 (in isoform 1)	Ubiquitination	-	51.68	21890473
573	Ubiquitination	VRITKLRKQVEEIFN HHHHHHHHHHHHHHC	69.96	-
620	Phosphorylation	PEGIPFRSPTWFGIP CCCCCCCCCCCCCCC	27.36	21815630
622	Phosphorylation	GIPFRSPTWFGIPRL CCCCCCCCCCCCCHH	34.37	28387310
636	Phosphorylation	LERIVRGSNKIKFVV HHHHHCCCCCEEEEE	25.12	20068231
640	Sumoylation	VRGSNKIKFVVKKPE HCCCCCEEEEEECCE	33.44	-
640	Sumoylation	VRGSNKIKFVVKKPE HCCCCCEEEEEECCE	33.44	-
645	Sumoylation	KIKFVVKKPELVISY CEEEEEECCEEEEEE	31.92	-
645	Acetylation	KIKFVVKKPELVISY CEEEEEECCEEEEEE	31.92	26051181
645	Sumoylation	KIKFVVKKPELVISY CEEEEEECCEEEEEE	31.92	-
651	Phosphorylation	KKPELVISYLPPGMA ECCEEEEEECCCCCH	17.09	26074081
652	Phosphorylation	KPELVISYLPPGMAS CCEEEEEECCCCCHH	16.47	26074081
659	Phosphorylation	YLPPGMASKINTKAL ECCCCCHHHHCHHHC	25.77	18669648
660	Acetylation	LPPGMASKINTKALQ CCCCCHHHHCHHHCC	30.36	25953088
660	Sumoylation	LPPGMASKINTKALQ CCCCCHHHHCHHHCC	30.36	28112733
660	Ubiquitination	LPPGMASKINTKALQ CCCCCHHHHCHHHCC	30.36	-
663	Phosphorylation	GMASKINTKALQSPK CCHHHHCHHHCCCCC	22.59	26074081
664	Sumoylation	MASKINTKALQSPKR CHHHHCHHHCCCCCC	42.48	-
664	Sumoylation	MASKINTKALQSPKR CHHHHCHHHCCCCCC	42.48	28112733
664	Ubiquitination	MASKINTKALQSPKR CHHHHCHHHCCCCCC	42.48	-
668	Phosphorylation	INTKALQSPKRPRSP HCHHHCCCCCCCCCC	32.99	23401153
670	Sumoylation	TKALQSPKRPRSPGS HHHCCCCCCCCCCCC	79.05	28112733
674	Phosphorylation	QSPKRPRSPGSNSKV CCCCCCCCCCCCCCC	35.97	10648599
677	Phosphorylation	KRPRSPGSNSKVPEI CCCCCCCCCCCCCEE	41.12	23927012
679	Phosphorylation	PRSPGSNSKVPEIEV CCCCCCCCCCCEEEE	36.41	23927012
680	Sumoylation	RSPGSNSKVPEIEVT CCCCCCCCCCEEEEE	67.09	28112733
687	Phosphorylation	KVPEIEVTVEGPNNN CCCEEEEEEECCCCC	10.47	30266825
698	Phosphorylation	PNNNNPQTSAVRTPT CCCCCCCCCCEECCC	21.65	22167270
699	Phosphorylation	NNNNPQTSAVRTPTQ CCCCCCCCCEECCCC	21.37	22167270
703	Phosphorylation	PQTSAVRTPTQTNGS CCCCCEECCCCCCCC	24.88	22167270
705	Phosphorylation	TSAVRTPTQTNGSNV CCCEECCCCCCCCCC	47.62	22167270
707	Phosphorylation	AVRTPTQTNGSNVPF CEECCCCCCCCCCCC	43.98	28387310
710	Phosphorylation	TPTQTNGSNVPFKPR CCCCCCCCCCCCCCC	36.40	22167270
711 (in isoform 2)	Ubiquitination	-	47.05	21890473
715	Sumoylation	NGSNVPFKPRGREFS CCCCCCCCCCCCEEE	27.95	-
715	Acetylation	NGSNVPFKPRGREFS CCCCCCCCCCCCEEE	27.95	25953088
715	Methylation	NGSNVPFKPRGREFS CCCCCCCCCCCCEEE	27.95	-
715	Sumoylation	NGSNVPFKPRGREFS CCCCCCCCCCCCEEE	27.95	28112733
715	Ubiquitination	NGSNVPFKPRGREFS CCCCCCCCCCCCEEE	27.95	-
722	Phosphorylation	KPRGREFSFEAWNAK CCCCCEEEHHHHHCH	19.88	22617229
729	Acetylation	SFEAWNAKITDLKQK EHHHHHCHHHHHHHH	42.81	26051181
729	Ubiquitination	SFEAWNAKITDLKQK EHHHHHCHHHHHHHH	42.81	-
731 (in isoform 4)	Ubiquitination	-	34.27	21890473
732 (in isoform 3)	Ubiquitination	-	56.17	21890473
734	Sumoylation	NAKITDLKQKVENLF HCHHHHHHHHHHHHH	51.38	-
734	Sumoylation	NAKITDLKQKVENLF HCHHHHHHHHHHHHH	51.38	-
736	Sumoylation	KITDLKQKVENLFNE HHHHHHHHHHHHHHH	50.34	-
736	Sumoylation	KITDLKQKVENLFNE HHHHHHHHHHHHHHH	50.34	-
736	Ubiquitination	KITDLKQKVENLFNE HHHHHHHHHHHHHHH	50.34	-
744	Sumoylation	VENLFNEKCGEALGL HHHHHHHHHHHHHCH	48.95	-
744	2-Hydroxyisobutyrylation	VENLFNEKCGEALGL HHHHHHHHHHHHHCH	48.95	-
744	Sumoylation	VENLFNEKCGEALGL HHHHHHHHHHHHHCH	48.95	-
744	Ubiquitination	VENLFNEKCGEALGL HHHHHHHHHHHHHCH	48.95	-
752	Sumoylation	CGEALGLKQAVKVPF HHHHHCHHHHCCCCH	34.12	-
752	Sumoylation	CGEALGLKQAVKVPF HHHHHCHHHHCCCCH	34.12	-
752	Ubiquitination	CGEALGLKQAVKVPF HHHHHCHHHHCCCCH	34.12	21906983
752 (in isoform 1)	Ubiquitination	-	34.12	21890473
756	Ubiquitination	LGLKQAVKVPFALFE HCHHHHCCCCHHHHH	47.40	-
764	Phosphorylation	VPFALFESFPEDFYV CCHHHHHHCCCCCEE	38.47	20068231
770	Phosphorylation	ESFPEDFYVEGLPEG HHCCCCCEECCCCCC	15.20	-
784	Phosphorylation	GVPFRRPSTFGIPRL CCCCCCCHHCCCCHH	34.26	25159151
785	O-linked_Glycosylation	VPFRRPSTFGIPRLE CCCCCCHHCCCCHHH	28.67	23301498
785	Phosphorylation	VPFRRPSTFGIPRLE CCCCCCHHCCCCHHH	28.67	30266825
806	Ubiquitination	AKIKFIIKKPEMFET CCEEEEECCHHHHHH	58.42	-
807	Sumoylation	KIKFIIKKPEMFETA CEEEEECCHHHHHHH	35.48	-
807	Sumoylation	KIKFIIKKPEMFETA CEEEEECCHHHHHHH	35.48	-
807	Ubiquitination	KIKFIIKKPEMFETA CEEEEECCHHHHHHH	35.48	-
813	Phosphorylation	KKPEMFETAIKESTS CCHHHHHHHHHHCCC	23.55	24732914
816	Sumoylation	EMFETAIKESTSSKS HHHHHHHHHCCCCCC	43.05	-
816	Sumoylation	EMFETAIKESTSSKS HHHHHHHHHCCCCCC	43.05	28112733
818	Phosphorylation	FETAIKESTSSKSPP HHHHHHHCCCCCCCC	28.70	30266825
819	Phosphorylation	ETAIKESTSSKSPPR HHHHHHCCCCCCCCC	37.80	30266825
820	Phosphorylation	TAIKESTSSKSPPRK HHHHHCCCCCCCCCC	45.08	30266825
821	Phosphorylation	AIKESTSSKSPPRKI HHHHCCCCCCCCCCC	36.92	23401153
823	Phosphorylation	KESTSSKSPPRKINS HHCCCCCCCCCCCCC	41.93	22167270
827	Sumoylation	SSKSPPRKINSSPNV CCCCCCCCCCCCCCC	52.60	28112733
827	Ubiquitination	SSKSPPRKINSSPNV CCCCCCCCCCCCCCC	52.60	-
830	Phosphorylation	SPPRKINSSPNVNTT CCCCCCCCCCCCCCC	51.12	30278072
831	Phosphorylation	PPRKINSSPNVNTTA CCCCCCCCCCCCCCC	18.92	30278072
836	Phosphorylation	NSSPNVNTTASGVED CCCCCCCCCCCCCCC	21.32	30278072
837	Phosphorylation	SSPNVNTTASGVEDL CCCCCCCCCCCCCCC	17.39	21955146
838 (in isoform 2)	Ubiquitination	-	11.40	21890473
839	Phosphorylation	PNVNTTASGVEDLNI CCCCCCCCCCCCCCE	41.08	21955146
850	Phosphorylation	DLNIIQVTIPDDDNE CCCEEEEECCCCCCH	15.49	28176443
858 (in isoform 4)	Ubiquitination	-	50.98	21890473
859 (in isoform 3)	Ubiquitination	-	4.78	21890473
860	Phosphorylation	DDDNERLSKVEKARQ CCCCHHHHHHHHHHH	40.66	23090842
861	Sumoylation	DDNERLSKVEKARQL CCCHHHHHHHHHHHH	60.03	-
861	Acetylation	DDNERLSKVEKARQL CCCHHHHHHHHHHHH	60.03	26051181
861	Sumoylation	DDNERLSKVEKARQL CCCHHHHHHHHHHHH	60.03	28112733
864	Sumoylation	ERLSKVEKARQLREQ HHHHHHHHHHHHHHH	52.43	28112733
877	Phosphorylation	EQVNDLFSRKFGEAI HHHHHHHHHHHHHHH	41.69	20068231
879	Sumoylation	VNDLFSRKFGEAIGM HHHHHHHHHHHHHCC	57.43	-
879	Sumoylation	VNDLFSRKFGEAIGM HHHHHHHHHHHHHCC	57.43	28112733
879	Ubiquitination	VNDLFSRKFGEAIGM HHHHHHHHHHHHHCC	57.43	21890473
879 (in isoform 1)	Ubiquitination	-	57.43	21890473
891	Sumoylation	IGMGFPVKVPYRKIT HCCCCCEECCCCEEE	37.42	-
891	Sumoylation	IGMGFPVKVPYRKIT HCCCCCEECCCCEEE	37.42	28112733
891	Ubiquitination	IGMGFPVKVPYRKIT HCCCCCEECCCCEEE	37.42	-
894	Phosphorylation	GFPVKVPYRKITINP CCCEECCCCEEEECC	27.76	25884760
896	Sumoylation	PVKVPYRKITINPGC CEECCCCEEEECCCC	38.06	-
896	Sumoylation	PVKVPYRKITINPGC CEECCCCEEEECCCC	38.06	-
896	Ubiquitination	PVKVPYRKITINPGC CEECCCCEEEECCCC	38.06	-
919	Phosphorylation	GVSFKAPSYLEISSM CCCCCCCCCEEHHHH	47.40	20068231
920	Phosphorylation	VSFKAPSYLEISSMR CCCCCCCCEEHHHHH	13.80	17360941
924	Phosphorylation	APSYLEISSMRRILD CCCCEEHHHHHHHHH	14.54	20068231
925	Phosphorylation	PSYLEISSMRRILDS CCCEEHHHHHHHHHH	23.21	20068231
926	Sulfoxidation	SYLEISSMRRILDSA CCEEHHHHHHHHHHH	2.39	21406390
927	Methylation	YLEISSMRRILDSAE CEEHHHHHHHHHHHH	25.16	-
932	Phosphorylation	SMRRILDSAEFIKFT HHHHHHHHHHEEEEE	26.67	24667141
957	Phosphorylation	NNQLVDQSESEGPVI CCEEECCCCCCCCCC	38.33	28348404
959	Phosphorylation	QLVDQSESEGPVIQE EEECCCCCCCCCCCC	53.77	27251275
967	Phosphorylation	EGPVIQESAEPSQLE CCCCCCCCCCHHHCC	22.89	28348404
971	Phosphorylation	IQESAEPSQLEVPAT CCCCCCHHHCCCCCC	38.61	20873877
978	Phosphorylation	SQLEVPATEEIKETD HHCCCCCCCCHHCCC	28.25	20873877
982	Sumoylation	VPATEEIKETDGSSQ CCCCCCHHCCCCCCC	58.82	-
984	Phosphorylation	ATEEIKETDGSSQIK CCCCHHCCCCCCCCC	40.43	26714015
987	Phosphorylation	EIKETDGSSQIKQEP CHHCCCCCCCCCCCC	23.14	25159151
988	Phosphorylation	IKETDGSSQIKQEPD HHCCCCCCCCCCCCC	41.26	25159151
991	Sumoylation	TDGSSQIKQEPDPTW CCCCCCCCCCCCCCC	40.76	-
991	Sumoylation	TDGSSQIKQEPDPTW CCCCCCCCCCCCCCC	40.76	25114211
991	Ubiquitination	TDGSSQIKQEPDPTW CCCCCCCCCCCCCCC	40.76	-
997	Phosphorylation	IKQEPDPTW------ CCCCCCCCC------	0.00	28985074

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
248	Y	Phosphorylation	Kinase	BTK	Q06187	PSP
248	Y	Phosphorylation	Kinase	JAK2	O60674	PSP
248	Y	Phosphorylation	Kinase	BTK	Q06187	Uniprot
248	Y	Phosphorylation	Kinase	SRC	P12931	PSP
248	Y	Phosphorylation	Kinase	SRC	P12931	PSP
249	Y	Phosphorylation	Kinase	SRC	P12931	PSP
357	Y	Phosphorylation	Kinase	BTK	Q06187	PSP
371	S	Phosphorylation	Kinase	PRKG1	Q13976	GPS
398	Y	Phosphorylation	Kinase	BTK	Q06187	Uniprot
412	S	Phosphorylation	Kinase	PKG1	Q13976	PSP
462	Y	Phosphorylation	Kinase	BTK	Q06187	PSP
503	Y	Phosphorylation	Kinase	BTK	Q06187	Uniprot
611	Y	Phosphorylation	Kinase	SRC	P12931	PSP
627	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
627	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
633	S	Phosphorylation	Kinase	MAPK3	P27361	GPS
633	S	Phosphorylation	Kinase	MAPK1	P28482	GPS
743	S	Phosphorylation	Kinase	PRKG1	Q13976	GPS
784	S	Phosphorylation	Kinase	PKG1	Q13976	PSP

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GTF2I_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GTF2I_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	12493763
HDAC2_HUMAN	HDAC2	physical	12493763
MYC_HUMAN	MYC	physical	8377829
KGP1_HUMAN	PRKG1	physical	12082086
BTK_HUMAN	BTK	physical	10373551
BTK_HUMAN	BTK	physical	9012831
ATF6A_HUMAN	ATF6	physical	11287625
SRF_HUMAN	SRF	physical	9584171
STAT1_HUMAN	STAT1	physical	9584171
STAT3_HUMAN	STAT3	physical	9584171
PIAS2_MOUSE	Pias2	physical	12193603
SIZ2_YEAST	NFI1	physical	12193603
USF1_HUMAN	USF1	physical	1961251
MK03_HUMAN	MAPK3	physical	10648599
HDAC3_HUMAN	HDAC3	physical	16943425
MK01_HUMAN	MAPK1	physical	11313464
OBF1_HUMAN	POU2AF1	physical	21549311
HDAC3_HUMAN	HDAC3	physical	21549311
BRCA1_HUMAN	BRCA1	physical	21407215
LEG3_HUMAN	LGALS3	physical	18662664
SLU7_HUMAN	SLU7	physical	18662664
RSMN_HUMAN	SNRPN	physical	18662664
SRSF9_HUMAN	SRSF9	physical	22939629
ODPA_HUMAN	PDHA1	physical	22939629
HNRH1_HUMAN	HNRNPH1	physical	22939629
M3K3_HUMAN	MAP3K3	physical	21988832
MK12_HUMAN	MAPK12	physical	21988832
TAB2_HUMAN	TAB2	physical	21988832
PUR8_HUMAN	ADSL	physical	22863883
PYRG2_HUMAN	CTPS2	physical	22863883
PRPS2_HUMAN	PRPS2	physical	22863883
RD23B_HUMAN	RAD23B	physical	22863883
RL28_HUMAN	RPL28	physical	22863883
PIAS2_HUMAN	PIAS2	physical	24722188
ZMYM3_HUMAN	ZMYM3	physical	24722188
AP2B1_HUMAN	AP2B1	physical	24722188
DPY30_HUMAN	DPY30	physical	24722188
GCC1_HUMAN	GCC1	physical	24722188
MTUS2_HUMAN	MTUS2	physical	24722188
TRAF6_HUMAN	TRAF6	physical	24722188
TCPB_HUMAN	CCT2	physical	26344197
TCPG_HUMAN	CCT3	physical	26344197
NF2IP_HUMAN	NFATC2IP	physical	26344197
TCPA_HUMAN	TCP1	physical	26344197
TRM1L_HUMAN	TRMT1L	physical	26344197
XRCC6_HUMAN	XRCC6	physical	26344197
MDM2_HUMAN	MDM2	physical	26656605
TULP3_HUMAN	TULP3	physical	27173435
ZMYM2_HUMAN	ZMYM2	physical	26275350
ZMYM3_HUMAN	ZMYM3	physical	26275350

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-210 AND SER-679, AND MASS SPECTROMETRY.
PubMed: 19413330

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-103 AND THR-558, ANDMASS SPECTROMETRY.
PubMed: 19690332

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-210 AND SER-679, AND MASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-103; SER-207; SER-210AND THR-558, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-515, AND MASSSPECTROMETRY.
PubMed: 18220336

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-210, AND MASSSPECTROMETRY.
PubMed: 16964243

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-679; THR-687 ANDSER-823, AND MASS SPECTROMETRY.
PubMed: 17081983

"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J.,Li J., Cohn M.A., Cantley L.C., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-517; SER-668 ANDSER-674, AND MASS SPECTROMETRY.
PubMed: 15302935

"cGMP-dependent protein kinase I beta physically and functionallyinteracts with the transcriptional regulator TFII-I.";
Casteel D.E., Zhuang S., Gudi T., Tang J., Vuica M., Desiderio S.,Pilz R.B.;
J. Biol. Chem. 277:32003-32014(2002).
Cited for: PHOSPHORYLATION AT SER-412 AND SER-784 BY PRKG1, AND INTERACTION WITHPRKG1.
PubMed: 12082086

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-558, AND MASSSPECTROMETRY.
PubMed: 17924679

"Induction of immunoglobulin heavy-chain transcription through thetranscription factor Bright requires TFII-I.";
Rajaiya J., Nixon J.C., Ayers N., Desgranges Z.P., Roy A.L.,Webb C.F.;
Mol. Cell. Biol. 26:4758-4768(2006).
Cited for: INTERACTION WITH ARID3A AND BTK, PHOSPHORYLATION AT TYR-248, ANDFUNCTION.
PubMed: 16738337

"Identification of phosphorylation sites for Bruton's tyrosine kinasewithin the transcriptional regulator BAP/TFII-I.";
Egloff A.M., Desiderio S.;
J. Biol. Chem. 276:27806-27815(2001).
Cited for: PHOSPHORYLATION AT TYR-248; TYR-398 AND TYR-503, INTERACTION WITH BTK,FUNCTION, AND MUTAGENESIS OF TYR-248; TYR-398; TYR-460 AND TYR-503.
PubMed: 11373296