dbPTM

NU107_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NU107_HUMAN
UniProt AC	P57740
Protein Name	Nuclear pore complex protein Nup107
Gene Name	NUP107
Organism	Homo sapiens (Human).
Sequence Length	925
Subcellular Localization	Nucleus membrane . Nucleus, nuclear pore complex . Chromosome, centromere, kinetochore . Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). D
Protein Description	Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. [PubMed: 12552102]
Protein Sequence	MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDRSGFGE -------CCCCCCCC	9.73	20068231
4	Phosphorylation	----MDRSGFGEISS ----CCCCCCCCCCC	33.92	30266825
10	Phosphorylation	RSGFGEISSPVIREA CCCCCCCCCHHHHHH	25.04	29255136
11	Phosphorylation	SGFGEISSPVIREAE CCCCCCCCHHHHHHH	28.93	19664994
20	Phosphorylation	VIREAEVTRTARKQS HHHHHHHHHHHHHHH	17.51	21949786
22	Phosphorylation	REAEVTRTARKQSAQ HHHHHHHHHHHHHHH	22.81	23879269
25	Methylation	EVTRTARKQSAQKRV HHHHHHHHHHHHHHH	46.25	116252445
37	Phosphorylation	KRVLLQASQDENFGN HHHHHHHHCCCCCCC	25.79	29255136
45	Phosphorylation	QDENFGNTTPRNQVI CCCCCCCCCCCCCCC	38.26	23401153
46	Phosphorylation	DENFGNTTPRNQVIP CCCCCCCCCCCCCCC	25.01	29255136
50	Ubiquitination	GNTTPRNQVIPRTPS CCCCCCCCCCCCCCC	35.48	21890473
55	Phosphorylation	RNQVIPRTPSSFRQP CCCCCCCCCCCCCCC	23.36	27273156
56	Ubiquitination	NQVIPRTPSSFRQPF CCCCCCCCCCCCCCC	29.29	32015554
56	Ubiquitination	NQVIPRTPSSFRQPF CCCCCCCCCCCCCCC	29.29	-
57	Phosphorylation	QVIPRTPSSFRQPFT CCCCCCCCCCCCCCC	41.31	23401153
58	Phosphorylation	VIPRTPSSFRQPFTP CCCCCCCCCCCCCCC	26.17	23401153
60	Asymmetric dimethylarginine	PRTPSSFRQPFTPTS CCCCCCCCCCCCCCH	45.25	-
60	Methylation	PRTPSSFRQPFTPTS CCCCCCCCCCCCCCH	45.25	24129315
64	Phosphorylation	SSFRQPFTPTSRSLL CCCCCCCCCCHHHHH	32.13	27273156
64	O-linked_Glycosylation	SSFRQPFTPTSRSLL CCCCCCCCCCHHHHH	32.13	30059200
66	Phosphorylation	FRQPFTPTSRSLLRQ CCCCCCCCHHHHHCC	33.44	30266825
67	Phosphorylation	RQPFTPTSRSLLRQP CCCCCCCHHHHHCCC	22.52	21712546
67	O-linked_Glycosylation	RQPFTPTSRSLLRQP CCCCCCCHHHHHCCC	22.52	30059200
68	Methylation	QPFTPTSRSLLRQPD CCCCCCHHHHHCCCC	33.53	58858727
69	Phosphorylation	PFTPTSRSLLRQPDI CCCCCHHHHHCCCCE	31.36	23927012
77	Phosphorylation	LLRQPDISCILGTGG HHCCCCEEEEECCCC	11.50	23401153
82	Phosphorylation	DISCILGTGGKSPRL CEEEEECCCCCCCCC	39.04	29255136
85	Ubiquitination	CILGTGGKSPRLTQS EEECCCCCCCCCCCC	59.64	33845483
85	Acetylation	CILGTGGKSPRLTQS EEECCCCCCCCCCCC	59.64	25953088
86	Phosphorylation	ILGTGGKSPRLTQSS EECCCCCCCCCCCCC	20.66	29255136
103	Phosphorylation	FGNLSMVTNLDDSNW CCCEEEEECCCCCCH	22.79	27732954
108	Phosphorylation	MVTNLDDSNWAAAFS EEECCCCCCHHHHHH	33.66	27732954
115	Phosphorylation	SNWAAAFSSQRSGLF CCHHHHHHHCCCCCC	22.34	26074081
116	Phosphorylation	NWAAAFSSQRSGLFT CHHHHHHHCCCCCCC	24.14	26074081
119	Phosphorylation	AAFSSQRSGLFTNTE HHHHHCCCCCCCCCC	32.01	26074081
123	Phosphorylation	SQRSGLFTNTEPHSI HCCCCCCCCCCCCCC	46.39	26074081
125	Phosphorylation	RSGLFTNTEPHSITE CCCCCCCCCCCCCCC	48.08	26074081
129	Phosphorylation	FTNTEPHSITEDVTI CCCCCCCCCCCCCEE	41.75	26074081
131	Phosphorylation	NTEPHSITEDVTISA CCCCCCCCCCCEEEE	29.19	26074081
135	Phosphorylation	HSITEDVTISAVMLR CCCCCCCEEEEEEEC	22.87	27732954
137	Phosphorylation	ITEDVTISAVMLRED CCCCCEEEEEEECCC	12.87	27732954
153	Phosphorylation	PGEAASMSMFSDFLQ CCHHHHHHHHHHHHH	17.74	20068231
156	Phosphorylation	AASMSMFSDFLQSFL HHHHHHHHHHHHHHH	20.86	20068231
161	Phosphorylation	MFSDFLQSFLKHSSS HHHHHHHHHHHCCCC	34.39	24719451
172	Ubiquitination	HSSSTVFDLVEEYEN CCCCCHHHHHHHHHH	45.53	27667366
172	Ubiquitination	HSSSTVFDLVEEYEN CCCCCHHHHHHHHHH	45.53	-
175	Ubiquitination	STVFDLVEEYENICG CCHHHHHHHHHHHCH	63.26	22817900
193	Phosphorylation	NILSKIVSRATPGLQ HHHHHHHHHCCCCHH	21.48	29514088
196	Phosphorylation	SKIVSRATPGLQKFS HHHHHHCCCCHHHHH	19.44	29514088
201	Ubiquitination	RATPGLQKFSKTASM HCCCCHHHHHHHHHH	57.56	21906983
201	Ubiquitination	RATPGLQKFSKTASM HCCCCHHHHHHHHHH	57.56	21890473
204	Ubiquitination	PGLQKFSKTASMLWL CCHHHHHHHHHHHHH	51.77	22817900
232	Phosphorylation	LYRDRIQSALEEESV HHHHHHHHHHHHCCC	32.23	-
251	Phosphorylation	AVNASEKTVVEALFQ ECCCCHHHHHHHHHC	26.23	28555341
261	Phosphorylation	EALFQRDSLVRQSQL HHHHCCCHHHHHHHH	30.84	20860994
276	Ubiquitination	VVDWLESIAKDEIGE HHHHHHHHHCCHHCC	3.94	21963094
276	Ubiquitination	VVDWLESIAKDEIGE HHHHHHHHHCCHHCC	3.94	-
296	Phosphorylation	EFYAKSVYWENTLHT HHHEEEHHHHCHHHH	17.69	28796482
303	Ubiquitination	YWENTLHTLKQRQLT HHHCHHHHHHHHHHH	38.47	29967540
303	Ubiquitination	YWENTLHTLKQRQLT HHHCHHHHHHHHHHH	38.47	-
305	Methylation	ENTLHTLKQRQLTSY HCHHHHHHHHHHHHH	44.59	42360801
305	Ubiquitination	ENTLHTLKQRQLTSY HCHHHHHHHHHHHHH	44.59	21906983
305	2-Hydroxyisobutyrylation	ENTLHTLKQRQLTSY HCHHHHHHHHHHHHH	44.59	-
315	Phosphorylation	QLTSYVGSVRPLVTE HHHHHHCCCCHHEEC	12.62	-
321	Phosphorylation	GSVRPLVTELDPDAP CCCCHHEECCCCCCC	38.21	-
332	Ubiquitination	PDAPIRQKMPLDDLD CCCCCCCCCCHHHCC	32.41	21906983
333	Sulfoxidation	DAPIRQKMPLDDLDR CCCCCCCCCHHHCCH	2.77	21406390
348	Ubiquitination	EDEVRLLKYLFTLIR HHHHHHHHHHHHHHH	44.49	-
349	Phosphorylation	DEVRLLKYLFTLIRA HHHHHHHHHHHHHHC	13.66	28188228
352	Phosphorylation	RLLKYLFTLIRAGMT HHHHHHHHHHHCCCC	20.76	28188228
353	Ubiquitination	LLKYLFTLIRAGMTE HHHHHHHHHHCCCCH	1.63	21963094
353	Ubiquitination	LLKYLFTLIRAGMTE HHHHHHHHHHCCCCH	1.63	-
359	Phosphorylation	TLIRAGMTEEAQRLC HHHHCCCCHHHHHHH	29.74	28188228
379	Ubiquitination	AWRAATLEGWKLYHD HHHHHCCCCCCCCCC	59.67	22505724
379	Ubiquitination	AWRAATLEGWKLYHD HHHHHCCCCCCCCCC	59.67	-
382	Ubiquitination	AATLEGWKLYHDPNV HHCCCCCCCCCCCCC	50.45	21906983
408	Ubiquitination	NPYRRIWKISCWRMA CCCCEEEEEEEHHHH	23.52	22505724
408	Acetylation	NPYRRIWKISCWRMA CCCCEEEEEEEHHHH	23.52	26051181
428	Phosphorylation	NRYERAIYAALSGNL HHHHHHHHHHHCCCH	5.71	28152594
432	Phosphorylation	RAIYAALSGNLKQLL HHHHHHHCCCHHHHH	22.40	28152594
462	Ubiquitination	VMVDSLVEQEIQTSV HHHHHHHHHHHHHCC	48.03	29967540
462	Ubiquitination	VMVDSLVEQEIQTSV HHHHHHHHHHHHHCC	48.03	-
472	Ubiquitination	IQTSVATLDETEELP HHHCCCCCCCCCCCC	3.95	22817900
472	Ubiquitination	IQTSVATLDETEELP HHHCCCCCCCCCCCC	3.95	-
473	Ubiquitination	QTSVATLDETEELPR HHCCCCCCCCCCCCH	57.31	22817900
473	Ubiquitination	QTSVATLDETEELPR HHCCCCCCCCCCCCH	57.31	-
475	Phosphorylation	SVATLDETEELPREY CCCCCCCCCCCCHHH	34.13	20860994
481	Ubiquitination	ETEELPREYLGANWT CCCCCCHHHHCCCCH	43.07	22817900
482	Ubiquitination	TEELPREYLGANWTL CCCCCHHHHCCCCHH	16.24	22817900
482	Phosphorylation	TEELPREYLGANWTL CCCCCHHHHCCCCHH	16.24	21406692
488	Phosphorylation	EYLGANWTLEKVFEE HHHCCCCHHHHHHHH	25.50	21406692
491	Ubiquitination	GANWTLEKVFEELQA CCCCHHHHHHHHHHC	56.17	29967540
501	Ubiquitination	EELQATDKKRVLEEN HHHHCCCHHHHHHHH	37.82	21906983
502	Ubiquitination	ELQATDKKRVLEENQ HHHCCCHHHHHHHHH	51.02	22817900
512	Phosphorylation	LEENQEHYHIVQKFL HHHHHHHHHHHHHHH	7.78	-
534	Ubiquitination	LMDEFSKWLSKSRNN HHHHHHHHHHHHCCC	12.50	21890473
569	Phosphorylation	LQTKEEVSIEVLKTY CCCCCCHHHHHHHHH	19.13	20068231
597	Ubiquitination	AFYTCHLPQDLAVAQ EEEEECCCHHHHHHH	11.28	21963094
597	Ubiquitination	AFYTCHLPQDLAVAQ EEEEECCCHHHHHHH	11.28	-
606	Ubiquitination	DLAVAQYALFLESVT HHHHHHHHHHHHHHC	4.63	21963094
608	Ubiquitination	AVAQYALFLESVTEF HHHHHHHHHHHHCHH	5.60	21963094
608	Ubiquitination	AVAQYALFLESVTEF HHHHHHHHHHHHCHH	5.60	-
616	Ubiquitination	LESVTEFEQRHHCLE HHHHCHHHHHHHHHH	40.24	-
617	Ubiquitination	ESVTEFEQRHHCLEL HHHCHHHHHHHHHHH	56.16	21963094
626	Ubiquitination	HHCLELAKEADLDVA HHHHHHHHHCCCCHH	67.09	21963094
637	Ubiquitination	LDVATITKTVVENIR CCHHEEEHHHHHHHH	35.16	21906983
642	Ubiquitination	ITKTVVENIRKKDNG EEHHHHHHHHHHCCC	27.96	33845483
645	Ubiquitination	TVVENIRKKDNGEFS HHHHHHHHHCCCCCC	61.76	-
646	Ubiquitination	VVENIRKKDNGEFSH HHHHHHHHCCCCCCC	46.72	29967540
652	Phosphorylation	KKDNGEFSHHDLAPA HHCCCCCCCCCCCCC	18.66	23898821
655	Ubiquitination	NGEFSHHDLAPALDT CCCCCCCCCCCCCCC	38.82	21890473
661	Ubiquitination	HDLAPALDTGTTEED CCCCCCCCCCCCHHH	45.24	27667366
661	Ubiquitination	HDLAPALDTGTTEED CCCCCCCCCCCCHHH	45.24	-
670	Ubiquitination	GTTEEDRLKIDVIDW CCCHHHHHCEEEEEE	9.85	27667366
671	Ubiquitination	TTEEDRLKIDVIDWL CCHHHHHCEEEEEEE	37.44	33845483
674	Ubiquitination	EDRLKIDVIDWLVFD HHHHCEEEEEEEECC	4.95	27667366
675	Ubiquitination	DRLKIDVIDWLVFDP HHHCEEEEEEEECCH	2.52	22817900
680	Ubiquitination	DVIDWLVFDPAQRAE EEEEEEECCHHHHHH	9.73	22817900
680	Ubiquitination	DVIDWLVFDPAQRAE EEEEEEECCHHHHHH	9.73	-
683	Ubiquitination	DWLVFDPAQRAEALK EEEECCHHHHHHHHH	17.21	27667366
684	Ubiquitination	WLVFDPAQRAEALKQ EEECCHHHHHHHHHH	50.97	22817900
685	Ubiquitination	LVFDPAQRAEALKQG EECCHHHHHHHHHHC	36.18	21963094
685	Ubiquitination	LVFDPAQRAEALKQG EECCHHHHHHHHHHC	36.18	-
689	Ubiquitination	PAQRAEALKQGNAIM HHHHHHHHHHCHHHH	2.99	22817900
690	Ubiquitination	AQRAEALKQGNAIMR HHHHHHHHHCHHHHH	64.31	21906983
694	Ubiquitination	EALKQGNAIMRKFLA HHHHHCHHHHHHHHH	12.09	21963094
702	Phosphorylation	IMRKFLASKKHEAAK HHHHHHHHCCHHHHH	44.37	22964224
703	Ubiquitination	MRKFLASKKHEAAKE HHHHHHHCCHHHHHH	53.17	27667366
704	Ubiquitination	RKFLASKKHEAAKEV HHHHHHCCHHHHHHH	44.15	22817900
709	Acetylation	SKKHEAAKEVFVKIP HCCHHHHHHHEEECC	62.55	24889073
709	Ubiquitination	SKKHEAAKEVFVKIP HCCHHHHHHHEEECC	62.55	21906983
714	Acetylation	AAKEVFVKIPQDSIA HHHHHEEECCHHHHH	36.89	24889081
714	Ubiquitination	AAKEVFVKIPQDSIA HHHHHEEECCHHHHH	36.89	21963094
724	Phosphorylation	QDSIAEIYNQCEEQG HHHHHHHHHHHHHCC	7.23	26714015
734	Phosphorylation	CEEQGMESPLPAEDD HHHCCCCCCCCCCCC	23.89	26714015
744	Ubiquitination	PAEDDNAIREHLCIR CCCCCHHHHHHHHHH	7.14	33845483
744	Ubiquitination	PAEDDNAIREHLCIR CCCCCHHHHHHHHHH	7.14	-
753	Ubiquitination	EHLCIRAYLEAHETF HHHHHHHHHHHHHHH	8.67	21890473
756	Ubiquitination	CIRAYLEAHETFNEW HHHHHHHHHHHHHHH	11.83	33845483
756	Ubiquitination	CIRAYLEAHETFNEW HHHHHHHHHHHHHHH	11.83	-
773	Ubiquitination	HMNSVPQKPALIPQP HHCCCCCCCCCCCCC	26.62	22817900
773	Ubiquitination	HMNSVPQKPALIPQP HHCCCCCCCCCCCCC	26.62	21890473
774	Ubiquitination	MNSVPQKPALIPQPT HCCCCCCCCCCCCCC	27.35	29967540
781	Phosphorylation	PALIPQPTFTEKVAH CCCCCCCCCCHHHHH	37.63	28555341
785	Ubiquitination	PQPTFTEKVAHEHKE CCCCCCHHHHHHHHH	41.48	21963094
785	Ubiquitination	PQPTFTEKVAHEHKE CCCCCCHHHHHHHHH	41.48	-
787	Ubiquitination	PTFTEKVAHEHKEKK CCCCHHHHHHHHHHC	17.26	22817900
794	Ubiquitination	AHEHKEKKYEMDFGI HHHHHHHCEEECCCC	47.75	21963094
796	Ubiquitination	EHKEKKYEMDFGIWK HHHHHCEEECCCCHH	40.95	22817900
803	Ubiquitination	EMDFGIWKGHLDALT EECCCCHHHHHHHHC	34.23	29967540
808	Ubiquitination	IWKGHLDALTADVKE CHHHHHHHHCHHHHH	17.11	33845483
814	Ubiquitination	DALTADVKEKMYNVL HHHCHHHHHHHCCEE	52.76	21963094
814	2-Hydroxyisobutyrylation	DALTADVKEKMYNVL HHHCHHHHHHHCCEE	52.76	-
816	Ubiquitination	LTADVKEKMYNVLLF HCHHHHHHHCCEEEE	40.75	22817900
837	Ubiquitination	VDVREDAKEDHERTH EECCHHHHHHHHHHH	75.81	33845483
858	Ubiquitination	KLCLPMLCFLLHTIL HHHHHHHHHHHHHHH	1.51	33845483
865	Ubiquitination	CFLLHTILHSTGQYQ HHHHHHHHHHCCCHH	2.47	21890473
865	Ubiquitination	CFLLHTILHSTGQYQ HHHHHHHHHHCCCHH	2.47	-
874	Ubiquitination	STGQYQECLQLADMV HCCCHHHHHHHHHHH	1.41	21890473
887	Ubiquitination	MVSSERHKLYLVFSK HHCCCCCCEEEEECH	45.08	33845483
893	O-linked_Glycosylation	HKLYLVFSKEELRKL CCEEEEECHHHHHHH	31.51	30059200
894	Ubiquitination	KLYLVFSKEELRKLL CEEEEECHHHHHHHH	43.68	21890473
894	Ubiquitination	KLYLVFSKEELRKLL CEEEEECHHHHHHHH	43.68	21890473
907	Phosphorylation	LLQKLRESSLMLLDQ HHHHHHHHHHHHHHC	23.49	30387612
908	Phosphorylation	LQKLRESSLMLLDQG HHHHHHHHHHHHHCC	17.03	30387612

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NU107_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NU107_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NU107_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NU133_HUMAN	NUP133	physical	15146057
NUP85_HUMAN	NUP85	physical	15146057
NU160_HUMAN	NUP160	physical	15146057
NU133_HUMAN	NUP133	physical	11564755
IMB1_HUMAN	KPNB1	physical	12894213
NU160_HUMAN	NUP160	physical	20676042
NU133_HUMAN	NUP133	physical	20676042
NUP98_HUMAN	NUP98	physical	20676042
NUP85_HUMAN	NUP85	physical	20676042
NUP43_HUMAN	NUP43	physical	20676042
NUP37_HUMAN	NUP37	physical	20676042
SEH1_HUMAN	SEH1L	physical	20676042
SEC13_HUMAN	SEC13	physical	20676042
WRIP1_HUMAN	WRNIP1	physical	20676042
NUP98_HUMAN	NUP98	physical	17360435
NU133_HUMAN	NUP133	physical	17360435
NU160_HUMAN	NUP160	physical	17360435
NUP85_HUMAN	NUP85	physical	17360435
NUP43_HUMAN	NUP43	physical	17360435
NUP37_HUMAN	NUP37	physical	17360435
SEH1_HUMAN	SEH1L	physical	17360435
SEC13_HUMAN	SEC13	physical	17360435
NU133_HUMAN	NUP133	physical	22939629
NU153_HUMAN	NUP153	physical	22939629
TP53B_HUMAN	TP53BP1	physical	22939629
PNPT1_HUMAN	PNPT1	physical	22939629
NU153_HUMAN	NUP153	physical	26344197
NUP37_HUMAN	NUP37	physical	26344197
SYNE1_HUMAN	SYNE1	physical	24927568
NU160_HUMAN	NUP160	physical	24927568
APC_HUMAN	APC	physical	24927568
PRKDC_HUMAN	PRKDC	physical	24927568
RRP1B_HUMAN	RRP1B	physical	24927568
NALCN_HUMAN	NALCN	physical	24927568
IMB1_HUMAN	KPNB1	physical	24927568
CD1E_HUMAN	CD1E	physical	24927568
ACTBL_HUMAN	ACTBL2	physical	24927568
HS90B_HUMAN	HSP90AB1	physical	24927568
XPO1_HUMAN	XPO1	physical	24927568
SEH1_HUMAN	SEH1L	physical	24927568
NU214_HUMAN	NUP214	physical	24927568
SENP1_HUMAN	SENP1	physical	24927568
SENP2_HUMAN	SENP2	physical	24927568
ELYS_HUMAN	AHCTF1	physical	24927568
RAGP1_HUMAN	RANGAP1	physical	24927568
H2AV_HUMAN	H2AFV	physical	24927568
NUP98_HUMAN	NUP98	physical	24927568
NU133_HUMAN	NUP133	physical	24927568
TPR_HUMAN	TPR	physical	24927568
NUP50_HUMAN	NUP50	physical	24927568
NU153_HUMAN	NUP153	physical	24927568
RBP2_HUMAN	RANBP2	physical	24927568
NUP85_HUMAN	NUP85	physical	24927568
ACLY_HUMAN	ACLY	physical	26496610
RCC1_HUMAN	RCC1	physical	26496610
GLE1_HUMAN	GLE1	physical	26496610
ITPR2_HUMAN	ITPR2	physical	26496610
IMB1_HUMAN	KPNB1	physical	26496610
IMA3_HUMAN	KPNA4	physical	26496610
NUP88_HUMAN	NUP88	physical	26496610
NUP98_HUMAN	NUP98	physical	26496610
RAN_HUMAN	RAN	physical	26496610
RBP2_HUMAN	RANBP2	physical	26496610
RAGP1_HUMAN	RANGAP1	physical	26496610
SEC13_HUMAN	SEC13	physical	26496610
TPR_HUMAN	TPR	physical	26496610
UBC9_HUMAN	UBE2I	physical	26496610
SUMO1_HUMAN	SUMO1	physical	26496610
NU214_HUMAN	NUP214	physical	26496610
AAAS_HUMAN	AAAS	physical	26496610
RAE1L_HUMAN	RAE1	physical	26496610
NU155_HUMAN	NUP155	physical	26496610
NUP93_HUMAN	NUP93	physical	26496610
NUP58_HUMAN	NUPL1	physical	26496610
WDR1_HUMAN	WDR1	physical	26496610
NU153_HUMAN	NUP153	physical	26496610
NXF1_HUMAN	NXF1	physical	26496610
IPO7_HUMAN	IPO7	physical	26496610
NUP50_HUMAN	NUP50	physical	26496610
NUPL2_HUMAN	NUPL2	physical	26496610
NU205_HUMAN	NUP205	physical	26496610
PO210_HUMAN	NUP210	physical	26496610
NU160_HUMAN	NUP160	physical	26496610
NU188_HUMAN	NUP188	physical	26496610
NUP62_HUMAN	NUP62	physical	26496610
NXT1_HUMAN	NXT1	physical	26496610
S61A1_HUMAN	SEC61A1	physical	26496610
NUP54_HUMAN	NUP54	physical	26496610
TM214_HUMAN	TMEM214	physical	26496610
NSMA3_HUMAN	SMPD4	physical	26496610
NDC1_HUMAN	NDC1	physical	26496610
NU133_HUMAN	NUP133	physical	26496610
SENP2_HUMAN	SENP2	physical	26496610
NUP37_HUMAN	NUP37	physical	26496610
NUP85_HUMAN	NUP85	physical	26496610
SEH1_HUMAN	SEH1L	physical	26496610
TM209_HUMAN	TMEM209	physical	26496610
NUP53_HUMAN	NUP35	physical	26496610
RUSD3_HUMAN	RPUSD3	physical	26496610
NUP43_HUMAN	NUP43	physical	26496610
RGPD8_HUMAN	RGPD8	physical	26496610
RAF1_HUMAN	RAF1	physical	27173435

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NU107_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-10 AND SER-11, AND MASS SPECTROMETRY.	19413330 [Abstract]
Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11; SER-37 AND THR-46,AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-10 AND SER-11, AND MASS SPECTROMETRY.	19413330 [Abstract]
"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle."; Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.; Mol. Cell 31:438-448(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11, AND MASSSPECTROMETRY.	18691976 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4; SER-11; SER-37;THR-46; THR-55; SER-58; THR-64; SER-69; SER-77 AND SER-86, AND MASSSPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Evaluation of the low-specificity protease elastase for large-scalephosphoproteome analysis."; Wang B., Malik R., Nigg E.A., Korner R.; Anal. Chem. 80:9526-9533(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11 AND THR-55, AND MASSSPECTROMETRY.	19007248 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-37, AND MASSSPECTROMETRY.	17525332 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11, AND MASSSPECTROMETRY.	17924679 [Abstract]
"Phosphoproteome analysis of the human mitotic spindle."; Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.; Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4; SER-11; THR-46;THR-55; SER-58 AND THR-64, AND MASS SPECTROMETRY.	16565220 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-86, AND MASSSPECTROMETRY.	17081983 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-46, AND MASSSPECTROMETRY.	16964243 [Abstract]