NU188_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NU188_HUMAN
• UniProt AC: Q5SRE5
• Protein Name: Nucleoporin NUP188 homolog
• Gene Name: NUP188
• Organism: Homo sapiens (Human).
• Sequence Length: 1749
• Subcellular Localization: Nucleus, nuclear pore complex .
• Protein Description: May function as a component of the nuclear pore complex (NPC)..
• Protein Sequence: MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKHWRRLLEGLSYYKPPSPSSAEKVKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDSVKTVLQDERQSQALILKIADYYYEERTCILRCVLHLLTYFQDERHPYRVEYADCVDKLEKELVSKYRQQFEELYKTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVLTKMFKEQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLICQDMDCLMLTFGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLQSLASGGNDCTTSTACMCVYGLLSFVLTSLELHTLGNQQDIIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELYKHKPHDVISHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVDVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSSLSQMISAEGMNAGGYGNLLMNSEQPQGEYGVTIAFLRLITTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVREQIGCLILELIHAILNLCHETDLHSSHTPSLQFLCICSLAYTEAGQTVINIMGIGVDTIDMVMAAQPRSDGAEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALSQHGAHGNNLIAVLAKYIYHKHDPALPRLAIQLLKRLATVAPMSVYACLGNDAAAIRDAFLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGMWSCLHAVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGTLSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSIEKRFAYWSGYVKSLAVHVAETEGSSCTSLLEYQMLVSAWRMLLIIATTHADIMHLTDSVVRRQLFLDVLDGTKALLLVPASVNCLRLGSMKCTLLLILLRQWKRELGSVDEILGPLTEILEGVLQADQQLMEKTKAKVFSAFITVLQMKEMKVSDIPQYSQLVLNVCETLQEEVIALFDQTRHSLALGSATEDKDSMETDDCSRSRHRDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEATLHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSTNGTAQTPSASRKSLDAPSWPGVYRLSMSLMEQLLKTLRYNFLPEALDFVGVHQERTLQCLNAVRTVQSLACLEEADHTVGFILQLSNFMKEWHFHLPQLMRDIQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVAQRVQRPPSAASAAPSSSKQPAADTEASEQQALHTVQYGLLKILSKTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNMLGELDKKKEPLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAMRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGAPSSPATGVLPSPQGKSTSLSKASPESQEPLIQLVQAFVRHMQR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAAAGGPC ------CCCCCCCCC	19.67	19413330
13	Phosphorylation	GGPCVRSSRELWTIL CCCCCCCHHHHHHHH	21.14	-
18	Phosphorylation	RSSRELWTILLGRSA CCHHHHHHHHHCHHH	17.86	23186163
24	Phosphorylation	WTILLGRSALRELSQ HHHHHCHHHHHHHHH	29.83	-
30	Phosphorylation	RSALRELSQIEAELN HHHHHHHHHHHHHHH	25.10	29449344
38	Acetylation	QIEAELNKHWRRLLE HHHHHHHHHHHHHHH	58.11	23749302
38	Malonylation	QIEAELNKHWRRLLE HHHHHHHHHHHHHHH	58.11	26320211
38	Ubiquitination	QIEAELNKHWRRLLE HHHHHHHHHHHHHHH	58.11	19608861
48	Phosphorylation	RRLLEGLSYYKPPSP HHHHHHHCCCCCCCC	36.95	23186163
49	Phosphorylation	RLLEGLSYYKPPSPS HHHHHHCCCCCCCCC	22.13	23186163
50	Phosphorylation	LLEGLSYYKPPSPSS HHHHHCCCCCCCCCH	17.40	23186163
51	Ubiquitination	LEGLSYYKPPSPSSA HHHHCCCCCCCCCHH	42.07	-
54	Phosphorylation	LSYYKPPSPSSAEKV HCCCCCCCCCHHHHH	46.04	23917254
56	Phosphorylation	YYKPPSPSSAEKVKA CCCCCCCCHHHHHHC	46.66	23186163
57	Phosphorylation	YKPPSPSSAEKVKAN CCCCCCCHHHHHHCC	43.78	23186163
62	Ubiquitination	PSSAEKVKANKDVAS CCHHHHHHCCCCCCH	58.26	27667366
65	Ubiquitination	AEKVKANKDVASPLK HHHHHCCCCCCHHHH	59.44	27667366
69	Phosphorylation	KANKDVASPLKELGL HCCCCCCHHHHHHCC	30.52	20873877
72	2-Hydroxyisobutyrylation	KDVASPLKELGLRIS CCCCHHHHHHCCHHH	55.03	-
72	Ubiquitination	KDVASPLKELGLRIS CCCCHHHHHHCCHHH	55.03	27667366
80	Ubiquitination	ELGLRISKFLGLDEE HHCCHHHHHHCCCHH	42.09	21963094
109	Ubiquitination	RGTRDSVKTVLQDER CCCHHHHHHHHCCHH	36.55	21906983
109 (in isoform 1)	Ubiquitination	-	36.55	21890473
128	Phosphorylation	LILKIADYYYEERTC HHHHHHHHHHHHHHH	10.02	20860994
129	Phosphorylation	ILKIADYYYEERTCI HHHHHHHHHHHHHHH	12.63	20860994
129 (in isoform 2)	Ubiquitination	-	12.63	21890473
164	Acetylation	EYADCVDKLEKELVS CHHHHHHHHHHHHHH	37.84	26051181
164	Ubiquitination	EYADCVDKLEKELVS CHHHHHHHHHHHHHH	37.84	29901268
167	Ubiquitination	DCVDKLEKELVSKYR HHHHHHHHHHHHHHH	67.78	29967540
172	Ubiquitination	LEKELVSKYRQQFEE HHHHHHHHHHHHHHH	36.65	27667366
181	Phosphorylation	RQQFEELYKTEAPTW HHHHHHHHCCCCCCC	21.10	28851738
182	Ubiquitination	QQFEELYKTEAPTWE HHHHHHHCCCCCCCC	53.14	22817900
182 (in isoform 1)	Ubiquitination	-	53.14	21890473
233 (in isoform 2)	Ubiquitination	-	3.39	21890473
237	Ubiquitination	SDLLVLTKMFKEQGF HHHHHHHHHHHHCCC	37.87	22817900
240	2-Hydroxyisobutyrylation	LVLTKMFKEQGFGSR HHHHHHHHHCCCCCC	45.70	-
240	Ubiquitination	LVLTKMFKEQGFGSR HHHHHHHHHCCCCCC	45.70	22817900
240 (in isoform 1)	Ubiquitination	-	45.70	21890473
338	Phosphorylation	HTLNPEETSSVVRKI HCCCHHHHHHHHHHH	25.33	25999147
339	Phosphorylation	TLNPEETSSVVRKIG CCCHHHHHHHHHHHC	25.15	25999147
340	Phosphorylation	LNPEETSSVVRKIGG CCHHHHHHHHHHHCC	31.86	20860994
344	Ubiquitination	ETSSVVRKIGGTAIQ HHHHHHHHHCCHHHH	33.81	22053931
344 (in isoform 1)	Ubiquitination	-	33.81	21890473
359 (in isoform 2)	Ubiquitination	-	17.84	21890473
368 (in isoform 2)	Ubiquitination	-	33.06	21890473
370 (in isoform 2)	Ubiquitination	-	44.71	21890473
389 (in isoform 2)	Ubiquitination	-	2.25	21890473
455 (in isoform 2)	Ubiquitination	-	7.47	21890473
456	Phosphorylation	QLLRALVSGKSTAKK HHHHHHHCCCCHHHH	41.16	22817900
458	Ubiquitination	LRALVSGKSTAKKVY HHHHHCCCCHHHHHH	36.81	27667366
463	Acetylation	SGKSTAKKVYSFLDK CCCCHHHHHHHHHHH	43.89	26051181
463	Ubiquitination	SGKSTAKKVYSFLDK CCCCHHHHHHHHHHH	43.89	29967540
465	Phosphorylation	KSTAKKVYSFLDKMS CCHHHHHHHHHHHHH	11.55	23312004
466	Phosphorylation	STAKKVYSFLDKMSF CHHHHHHHHHHHHHH	23.48	23312004
470	Ubiquitination	KVYSFLDKMSFYNEL HHHHHHHHHHHHHHH	38.29	22817900
470 (in isoform 1)	Ubiquitination	-	38.29	21890473
479	Ubiquitination	SFYNELYKHKPHDVI HHHHHHHHCCCCCEE	58.75	33845483
479 (in isoform 1)	Ubiquitination	-	58.75	21890473
481	Ubiquitination	YNELYKHKPHDVISH HHHHHHCCCCCEEEC	39.64	22817900
481 (in isoform 1)	Ubiquitination	-	39.64	21890473
487	Phosphorylation	HKPHDVISHEDGTLW CCCCCEEECCCCCCE	22.22	30622161
500	Ubiquitination	LWRRQTPKLLYPLGG CEECCCCCEEEECCC	55.29	23000965
500 (in isoform 1)	Ubiquitination	-	55.29	21890473
503	Phosphorylation	RQTPKLLYPLGGQTN CCCCCEEEECCCCCC	13.57	28152594
517 (in isoform 2)	Ubiquitination	-	19.06	21890473
522	Sulfoxidation	QGTVGQVMLDDRAYL CCCCEEEEECCCEEE	2.33	21406390
526	Methylation	GQVMLDDRAYLVRWE EEEEECCCEEEEEEE	25.46	115485829
566	Acetylation	IQHCQRVKPIIDLVH HHHHHHHHHHHHHHH	32.46	26051181
566	Ubiquitination	IQHCQRVKPIIDLVH HHHHHHHHHHHHHHH	32.46	21906983
566 (in isoform 1)	Ubiquitination	-	32.46	21890473
605	Phosphorylation	QRLTTVISPPVDVIA HHHHHCCCCCHHHHH	20.86	20068231
609 (in isoform 2)	Ubiquitination	-	31.70	21890473
628	Ubiquitination	LAARNPAKVWTDLRH HHHCCHHHHHHCCCC	39.29	21906983
628 (in isoform 1)	Ubiquitination	-	39.29	21890473
688	Phosphorylation	IAFLRLITTLVKGQL HHHHHHHHHHHHCCC	20.76	27251275
689	Phosphorylation	AFLRLITTLVKGQLG HHHHHHHHHHHCCCC	23.66	27251275
697	Phosphorylation	LVKGQLGSTQSQGLV HHHCCCCCCCCCCHH	31.68	27251275
698	Phosphorylation	VKGQLGSTQSQGLVP HHCCCCCCCCCCHHH	30.37	27251275
700	Phosphorylation	GQLGSTQSQGLVPCV CCCCCCCCCCHHHHH	26.72	27251275
701 (in isoform 2)	Ubiquitination	-	39.15	21890473
718	Phosphorylation	LKEMLPSYHKWRYNS HHHHCHHHHHCCCCC	12.89	-
720	Ubiquitination	EMLPSYHKWRYNSHG HHCHHHHHCCCCCCC	25.74	21890473
720 (in isoform 1)	Ubiquitination	-	25.74	21890473
765 (in isoform 2)	Ubiquitination	-	1.62	21890473
797 (in isoform 2)	Ubiquitination	-	34.99	21890473
798	Phosphorylation	VMAAQPRSDGAEGQG EEEECCCCCCCCCCC	47.26	23403867
812	Acetylation	GQGQLLIKTVKLAFS CCCCEEEEEEEEEEE	47.43	26051181
812	Ubiquitination	GQGQLLIKTVKLAFS CCCCEEEEEEEEEEE	47.43	23000965
812 (in isoform 1)	Ubiquitination	-	47.43	21890473
815	Ubiquitination	QLLIKTVKLAFSVTN CEEEEEEEEEEEEEC	39.05	23000965
862	Ubiquitination	LAKYIYHKHDPALPR HHHHHHHCCCCHHHH	32.50	33845483
876	Acetylation	RLAIQLLKRLATVAP HHHHHHHHHHHCCCC	54.69	26051181
876	Ubiquitination	RLAIQLLKRLATVAP HHHHHHHHHHHCCCC	54.69	23000965
876 (in isoform 1)	Ubiquitination	-	54.69	21890473
903	Phosphorylation	AIRDAFLTRLQSKIE HHHHHHHHHHHHHHH	23.91	28674419
907	Phosphorylation	AFLTRLQSKIEDMRI HHHHHHHHHHHHHHH	39.94	28674419
908	Ubiquitination	FLTRLQSKIEDMRIK HHHHHHHHHHHHHHH	36.83	22817900
908 (in isoform 1)	Ubiquitination	-	36.83	21890473
998	Phosphorylation	LWQDRRDSAMLVLRT HHHCCCCCCEEEEEC	17.48	20068231
1000	Sulfoxidation	QDRRDSAMLVLRTKP HCCCCCCEEEEECCH	2.85	21406390
1060	Ubiquitination	GSLDQSLKDTLKKFS CCCCHHHHHHHHHCC	54.64	29967540
1065	Acetylation	SLKDTLKKFSIEKRF HHHHHHHHCCHHHHH	47.67	30590949
1070	Acetylation	LKKFSIEKRFAYWSG HHHCCHHHHHHHHHH	51.66	26051181
1070	Ubiquitination	LKKFSIEKRFAYWSG HHHCCHHHHHHHHHH	51.66	27667366
1081	Phosphorylation	YWSGYVKSLAVHVAE HHHHHHHEEEEEHHH	16.12	24043423
1089	Phosphorylation	LAVHVAETEGSSCTS EEEEHHHCCCCCCHH	35.59	24043423
1092	Phosphorylation	HVAETEGSSCTSLLE EHHHCCCCCCHHHHH	18.93	24043423
1093	Phosphorylation	VAETEGSSCTSLLEY HHHCCCCCCHHHHHH	32.07	24043423
1095	Phosphorylation	ETEGSSCTSLLEYQM HCCCCCCHHHHHHHH	25.10	24043423
1096	Phosphorylation	TEGSSCTSLLEYQML CCCCCCHHHHHHHHH	34.97	24043423
1100	Phosphorylation	SCTSLLEYQMLVSAW CCHHHHHHHHHHHHH	10.13	24043423
1105	Phosphorylation	LEYQMLVSAWRMLLI HHHHHHHHHHHHHHH	20.39	24043423
1180 (in isoform 2)	Ubiquitination	-	4.69	21890473
1252	Phosphorylation	LFDQTRHSLALGSAT HHHHCCHHHHCCCCC	16.43	28555341
1257	Phosphorylation	RHSLALGSATEDKDS CHHHHCCCCCCCHHC	32.63	25849741
1259	Phosphorylation	SLALGSATEDKDSME HHHCCCCCCCHHCCC	46.55	23312004
1262	Acetylation	LGSATEDKDSMETDD CCCCCCCHHCCCCCC	45.53	25953088
1262	Ubiquitination	LGSATEDKDSMETDD CCCCCCCHHCCCCCC	45.53	24816145
1264	Phosphorylation	SATEDKDSMETDDCS CCCCCHHCCCCCCCC	25.02	29214152
1267	Phosphorylation	EDKDSMETDDCSRSR CCHHCCCCCCCCHHH	28.61	23312004
1270	Glutathionylation	DSMETDDCSRSRHRD HCCCCCCCCHHHCCC	3.97	22555962
1271	Phosphorylation	SMETDDCSRSRHRDQ CCCCCCCCHHHCCCC	40.04	23312004
1275 (in isoform 2)	Ubiquitination	-	38.63	21890473
1291	Ubiquitination	VLGLHLAKELCEVDE EEHHHHHHHHCCCCC	58.54	22817900
1291 (in isoform 1)	Ubiquitination	-	58.54	21890473
1298 (in isoform 2)	Ubiquitination	-	69.90	-
1342	Phosphorylation	ATLHLLLTLARTQQG HHHHHHHHHHHHHCC	20.52	24719451
1386	Malonylation	QTPSASRKSLDAPSW CCCCCCCCCCCCCCC	53.53	26320211
1386	Ubiquitination	QTPSASRKSLDAPSW CCCCCCCCCCCCCCC	53.53	22817900
1386 (in isoform 1)	Ubiquitination	-	53.53	21890473
1387	Phosphorylation	TPSASRKSLDAPSWP CCCCCCCCCCCCCCC	30.30	27134283
1400	Phosphorylation	WPGVYRLSMSLMEQL CCHHHHHHHHHHHHH	9.42	21406692
1402	Phosphorylation	GVYRLSMSLMEQLLK HHHHHHHHHHHHHHH	22.61	21406692
1409	Acetylation	SLMEQLLKTLRYNFL HHHHHHHHHHHHCCC	54.85	20167786
1409	Ubiquitination	SLMEQLLKTLRYNFL HHHHHHHHHHHHCCC	54.85	23503661
1413	Phosphorylation	QLLKTLRYNFLPEAL HHHHHHHHCCCHHHH	17.24	22798277
1422 (in isoform 2)	Ubiquitination	-	5.54	21890473
1430	Phosphorylation	VGVHQERTLQCLNAV CCCCHHHHHHHHHHH	22.04	20068231
1496	Ubiquitination	TSLLHSRKMLQHYLQ HHHHHHHHHHHHHHH	47.15	23000965
1505	Acetylation	LQHYLQNKNGDGLPS HHHHHHCCCCCCCCH	49.71	26051181
1505	Ubiquitination	LQHYLQNKNGDGLPS HHHHHHCCCCCCCCH	49.71	29967540
1512	Phosphorylation	KNGDGLPSAVAQRVQ CCCCCCCHHHHHHCC	40.18	26074081
1523	Phosphorylation	QRVQRPPSAASAAPS HHCCCCCCHHHCCCC	38.87	29255136
1526	Phosphorylation	QRPPSAASAAPSSSK CCCCCHHHCCCCCCC	25.36	30266825
1530	Phosphorylation	SAASAAPSSSKQPAA CHHHCCCCCCCCCCC	42.38	23403867
1531	Phosphorylation	AASAAPSSSKQPAAD HHHCCCCCCCCCCCC	40.26	23403867
1532	Phosphorylation	ASAAPSSSKQPAADT HHCCCCCCCCCCCCC	39.38	23403867
1533	Ubiquitination	SAAPSSSKQPAADTE HCCCCCCCCCCCCCC	63.35	21906983
1533 (in isoform 1)	Ubiquitination	-	63.35	21890473
1598	Phosphorylation	ALSFTTPTFDSEVAP EEECCCCCCCCCCCC	37.67	19369195
1606	Phosphorylation	FDSEVAPSFGTLLAT CCCCCCCCHHHHHHH	26.94	17494752
1610 (in isoform 2)	Ubiquitination	-	2.91	21890473
1616 (in isoform 2)	Ubiquitination	-	5.80	-
1627	Ubiquitination	MLGELDKKKEPLTQA HHCCHHCCCCCCHHH	63.13	29967540
1628	Ubiquitination	LGELDKKKEPLTQAV HCCHHCCCCCCHHHH	71.01	29967540
1632	Phosphorylation	DKKKEPLTQAVGLST HCCCCCCHHHHCCCC	25.79	20860994
1638	Phosphorylation	LTQAVGLSTQAEGTR CHHHHCCCCCCCCHH	16.73	23532336
1639	Phosphorylation	TQAVGLSTQAEGTRT HHHHCCCCCCCCHHH	36.52	27251789
1644	Phosphorylation	LSTQAEGTRTLKSLL CCCCCCCHHHHHHHH	16.40	23532336
1646	Phosphorylation	TQAEGTRTLKSLLMF CCCCCHHHHHHHHHH	38.07	23898821
1660	Phosphorylation	FTMENCFYLLISQAM HHHHHHHHHHHHHHH	11.64	-
1684	Ubiquitination	PRDKQRMKQELSSEL HHHHHHHHHHHHHHH	42.69	-
1688	Phosphorylation	QRMKQELSSELSTLL HHHHHHHHHHHHHHH	22.48	21406692
1689	Phosphorylation	RMKQELSSELSTLLS HHHHHHHHHHHHHHH	56.00	21406692
1692	Phosphorylation	QELSSELSTLLSSLS HHHHHHHHHHHHHHH	16.98	21406692
1693	Phosphorylation	ELSSELSTLLSSLSR HHHHHHHHHHHHHHH	44.32	21406692
1696	Phosphorylation	SELSTLLSSLSRYFR HHHHHHHHHHHHHHH	32.14	20068231
1697	Phosphorylation	ELSTLLSSLSRYFRR HHHHHHHHHHHHHHC	30.27	20068231
1699	Phosphorylation	STLLSSLSRYFRRGA HHHHHHHHHHHHCCC	27.21	21406692
1701	Phosphorylation	LLSSLSRYFRRGAPS HHHHHHHHHHCCCCC	9.69	21406692
1708	Phosphorylation	YFRRGAPSSPATGVL HHHCCCCCCCCCCCC	48.71	29255136
1709	Phosphorylation	FRRGAPSSPATGVLP HHCCCCCCCCCCCCC	19.93	29255136
1712	Phosphorylation	GAPSSPATGVLPSPQ CCCCCCCCCCCCCCC	31.07	29255136
1717	Phosphorylation	PATGVLPSPQGKSTS CCCCCCCCCCCCCCC	26.20	29255136
1721	Ubiquitination	VLPSPQGKSTSLSKA CCCCCCCCCCCCCCC	45.36	22817900
1721 (in isoform 1)	Ubiquitination	-	45.36	21890473
1726	Phosphorylation	QGKSTSLSKASPESQ CCCCCCCCCCCHHHC	26.41	22468782
1727	Ubiquitination	GKSTSLSKASPESQE CCCCCCCCCCHHHCH	59.17	21987572
1729	Phosphorylation	STSLSKASPESQEPL CCCCCCCCHHHCHHH	32.70	25627689

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NU188_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NU188_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NU188_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NUP93_HUMAN	NUP93	physical	26344197

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-1708; SER-1709; THR-1712 AND SER-1717, AND MASSSPECTROMETRY.
PubMed: 19413330

"Lysine acetylation targets protein complexes and co-regulates majorcellular functions.";
Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.;
Science 325:834-840(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-38, AND MASS SPECTROMETRY.
PubMed: 19608861

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1709; THR-1712 ANDSER-1717, AND MASS SPECTROMETRY.
PubMed: 19690332

"Large-scale proteomics analysis of the human kinome.";
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G.,Mann M., Daub H.;
Mol. Cell. Proteomics 8:1751-1764(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1708, AND MASSSPECTROMETRY.
PubMed: 19369195

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, PHOSPHORYLATION [LARGESCALE ANALYSIS] AT SER-1708; SER-1709; THR-1712 AND SER-1717, AND MASSSPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1708; SER-1709 ANDSER-1717, AND MASS SPECTROMETRY.
PubMed: 18669648

"Kinase-selective enrichment enables quantitative phosphoproteomics ofthe kinome across the cell cycle.";
Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,Greff Z., Keri G., Stemmann O., Mann M.;
Mol. Cell 31:438-448(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1708; SER-1709 ANDSER-1717, AND MASS SPECTROMETRY.
PubMed: 18691976

"Phosphoproteome analysis of the human mitotic spindle.";
Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.;
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1709 AND SER-1717, ANDMASS SPECTROMETRY.
PubMed: 16565220

"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1717, AND MASSSPECTROMETRY.
PubMed: 16964243