KI20B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: KI20B_HUMAN
• UniProt AC: Q96Q89
• Protein Name: Kinesin-like protein KIF20B {ECO:0000305}
• Gene Name: KIF20B {ECO:0000312|HGNC:HGNC:7212}
• Organism: Homo sapiens (Human).
• Sequence Length: 1820
• Subcellular Localization: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . Midbody . Cell projection, axon . Cell projection, growth
• Protein Description: Plus-end-directed motor enzyme that is required for completion of cytokinesis. [PubMed: 11470801]
• Protein Sequence: MESNFNQEGVPRPSYVFSADPIARPSEINFDGIKLDLSHEFSLVAPNTEANSFESKDYLQVCLRIRPFTQSEKELESEGCVHILDSQTVVLKEPQCILGRLSEKSSGQMAQKFSFSKVFGPATTQKEFFQGCIMQPVKDLLKGQSRLIFTYGLTNSGKTYTFQGTEENIGILPRTLNVLFDSLQERLYTKMNLKPHRSREYLRLSSEQEKEEIASKSALLRQIKEVTVHNDSDDTLYGSLTNSLNISEFEESIKDYEQANLNMANSIKFSVWVSFFEIYNEYIYDLFVPVSSKFQKRKMLRLSQDVKGYSFIKDLQWIQVSDSKEAYRLLKLGIKHQSVAFTKLNNASSRSHSIFTVKILQIEDSEMSRVIRVSELSLCDLAGSERTMKTQNEGERLRETGNINTSLLTLGKCINVLKNSEKSKFQQHVPFRESKLTHYFQSFFNGKGKICMIVNISQCYLAYDETLNVLKFSAIAQKVCVPDTLNSSQEKLFGPVKSSQDVSLDSNSNSKILNVKRATISWENSLEDLMEDEDLVEELENAEETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVETEETHNYVGFEDIIDSLQDNVADIKKQAEIAHLYIASLPDPQEATACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTRFPKPELEIQFTPLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKCENKKNATPRTNLKFPISDDRNSSVKKEQKVAIRPSSKKTYSLRSQASIIGVNLATKKKEGTLQKFGDFLQHSPSILQSKAKKIIETMSSSKLSNVEASKENVSQPKRAKRKLYTSEISSPIDISGQVILMDQKMKESDHQIIKRRLRTKTAK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MESNFNQEGV -----CCCCCCCCCC	59.59	25002506
14	Phosphorylation	QEGVPRPSYVFSADP CCCCCCCCCEEECCC	34.90	25002506
15	Phosphorylation	EGVPRPSYVFSADPI CCCCCCCCEEECCCC	14.27	25002506
18	O-linked_Glycosylation	PRPSYVFSADPIARP CCCCCEEECCCCCCC	23.01	OGP
18	Phosphorylation	PRPSYVFSADPIARP CCCCCEEECCCCCCC	23.01	25002506
26	Phosphorylation	ADPIARPSEINFDGI CCCCCCCCEECCCCE	45.62	-
37 (in isoform 5)	Ubiquitination	-	9.02	21890473
38	Phosphorylation	DGIKLDLSHEFSLVA CCEEEECCCCEEEEC	22.19	22199227
42	Phosphorylation	LDLSHEFSLVAPNTE EECCCCEEEECCCCC	20.96	22199227
69	Phosphorylation	CLRIRPFTQSEKELE HHHHCCCCCCHHHHH	33.59	22210691
71	Phosphorylation	RIRPFTQSEKELESE HHCCCCCCHHHHHHC	47.80	22210691
104	Ubiquitination	ILGRLSEKSSGQMAQ HHHCCCCCCCCCHHH	46.69	29967540
104 (in isoform 2)	Ubiquitination	-	46.69	-
105	Phosphorylation	LGRLSEKSSGQMAQK HHCCCCCCCCCHHHH	35.33	-
106	Phosphorylation	GRLSEKSSGQMAQKF HCCCCCCCCCHHHHC	44.08	-
112	Ubiquitination	SSGQMAQKFSFSKVF CCCCHHHHCCCCCCC	33.18	22817900
112 (in isoform 2)	Ubiquitination	-	33.18	-
114	Phosphorylation	GQMAQKFSFSKVFGP CCHHHHCCCCCCCCC	35.33	24719451
116	Phosphorylation	MAQKFSFSKVFGPAT HHHHCCCCCCCCCCC	27.06	-
117	Ubiquitination	AQKFSFSKVFGPATT HHHCCCCCCCCCCCC	39.30	21890473
117	Ubiquitination	AQKFSFSKVFGPATT HHHCCCCCCCCCCCC	39.30	22817900
117 (in isoform 1)	Ubiquitination	-	39.30	21890473
117 (in isoform 2)	Ubiquitination	-	39.30	21890473
117 (in isoform 3)	Ubiquitination	-	39.30	21890473
117 (in isoform 4)	Ubiquitination	-	39.30	21890473
123	Phosphorylation	SKVFGPATTQKEFFQ CCCCCCCCCCHHHHC	32.66	-
124	Phosphorylation	KVFGPATTQKEFFQG CCCCCCCCCHHHHCC	39.49	-
126	Ubiquitination	FGPATTQKEFFQGCI CCCCCCCHHHHCCCC	55.16	29967540
138 (in isoform 2)	Ubiquitination	-	49.71	-
150	Phosphorylation	GQSRLIFTYGLTNSG CCCEEEEEEEECCCC	15.08	28985074
151	Phosphorylation	QSRLIFTYGLTNSGK CCEEEEEEEECCCCC	10.21	28985074
161	Phosphorylation	TNSGKTYTFQGTEEN CCCCCEEEEECCHHH	18.08	28985074
182	Phosphorylation	TLNVLFDSLQERLYT HHHHHHHHHHHHHHH	25.31	23312004
188	Phosphorylation	DSLQERLYTKMNLKP HHHHHHHHHHCCCCC	15.55	30622161
189	Phosphorylation	SLQERLYTKMNLKPH HHHHHHHHHCCCCCC	28.54	30622161
190 (in isoform 2)	Ubiquitination	-	16.54	-
205	Phosphorylation	SREYLRLSSEQEKEE CHHHHHCCCHHHHHH	25.95	30108239
206	Phosphorylation	REYLRLSSEQEKEEI HHHHHCCCHHHHHHH	48.14	28450419
215	Phosphorylation	QEKEEIASKSALLRQ HHHHHHHCHHHHHHH	32.57	23312004
216	Ubiquitination	EKEEIASKSALLRQI HHHHHHCHHHHHHHH	30.63	29967540
216 (in isoform 2)	Ubiquitination	-	30.63	-
303	Phosphorylation	KRKMLRLSQDVKGYS HHHHHHHCCCCCCCH	20.21	20068231
303 (in isoform 3)	Phosphorylation	-	20.21	-
307	Ubiquitination	LRLSQDVKGYSFIKD HHHCCCCCCCHHHCC	61.49	29967540
307 (in isoform 2)	Ubiquitination	-	61.49	-
309	Phosphorylation	LSQDVKGYSFIKDLQ HCCCCCCCHHHCCCC	8.49	19835603
310	Phosphorylation	SQDVKGYSFIKDLQW CCCCCCCHHHCCCCE	29.21	19835603
310 (in isoform 3)	Phosphorylation	-	29.21	-
321	Phosphorylation	DLQWIQVSDSKEAYR CCCEEEECCCHHHHH	21.57	17924679
321 (in isoform 3)	Phosphorylation	-	21.57	-
323	Phosphorylation	QWIQVSDSKEAYRLL CEEEECCCHHHHHHH	25.53	17924679
323 (in isoform 3)	Phosphorylation	-	25.53	-
324	Ubiquitination	WIQVSDSKEAYRLLK EEEECCCHHHHHHHH	51.89	29967540
335	Ubiquitination	RLLKLGIKHQSVAFT HHHHHCCCCCEEEEE	33.52	29967540
343	Ubiquitination	HQSVAFTKLNNASSR CCEEEEEECCCCCCC	42.64	21963094
348	Phosphorylation	FTKLNNASSRSHSIF EEECCCCCCCCCCCE	28.54	24275569
412	Ubiquitination	TSLLTLGKCINVLKN HHHHHHHHHHHHHHC	34.75	29967540
424	Ubiquitination	LKNSEKSKFQQHVPF HHCCCCCCCHHCCCC	59.25	29967540
424 (in isoform 2)	Ubiquitination	-	59.25	-
426	Ubiquitination	NSEKSKFQQHVPFRE CCCCCCCHHCCCCCH	35.89	32015554
442	O-linked_Glycosylation	KLTHYFQSFFNGKGK HHHHHHHHHHCCCCE	23.16	30379171
478	Ubiquitination	KFSAIAQKVCVPDTL CHHHHHHHHCCCCCC	28.69	21963094
488	Phosphorylation	VPDTLNSSQEKLFGP CCCCCCCCCHHHHCC	41.09	17525332
488 (in isoform 3)	Phosphorylation	-	41.09	-
491	Ubiquitination	TLNSSQEKLFGPVKS CCCCCCHHHHCCCCC	41.29	29967540
497	Ubiquitination	EKLFGPVKSSQDVSL HHHHCCCCCCCCEEC	47.74	21963094
498	Phosphorylation	KLFGPVKSSQDVSLD HHHCCCCCCCCEECC	33.20	27690223
499	Phosphorylation	LFGPVKSSQDVSLDS HHCCCCCCCCEECCC	25.36	27690223
503	Phosphorylation	VKSSQDVSLDSNSNS CCCCCCEECCCCCCC	34.45	27690223
506	Phosphorylation	SQDVSLDSNSNSKIL CCCEECCCCCCCCEE	47.66	28985074
511	Ubiquitination	LDSNSNSKILNVKRA CCCCCCCCEECEEEE	56.30	21963094
516	Ubiquitination	NSKILNVKRATISWE CCCEECEEEEEECCH	34.93	21963094
525	Phosphorylation	ATISWENSLEDLMED EEECCHHHHHHHHCC	22.94	27067055
560	Phosphorylation	LDEDLDKTLEENKAF CHHHHHHHHHHHHCC	38.78	30266825
565	Ubiquitination	DKTLEENKAFISHEE HHHHHHHHCCCCHHH	48.21	29967540
573	Ubiquitination	AFISHEEKRKLLDLI CCCCHHHHHHHHHHH	52.42	29967540
575	Ubiquitination	ISHEEKRKLLDLIED CCHHHHHHHHHHHHH	65.55	29967540
584	Ubiquitination	LDLIEDLKKKLINEK HHHHHHHHHHHCHHH	61.25	29967540
594	Ubiquitination	LINEKKEKLTLEFKI HCHHHHHHCEEEEEC	56.50	29967540
621	Ubiquitination	AQREADFKETLLQER HHCCCHHHHHHHHHH	50.79	29967540
621 (in isoform 2)	Ubiquitination	-	50.79	-
643	Ubiquitination	ERRLAIFKDLVGKCD HHHHHHHHHHHCCCC	44.00	23000965
643 (in isoform 2)	Ubiquitination	-	44.00	-
648	Ubiquitination	IFKDLVGKCDTREEA HHHHHHCCCCCHHHH	22.81	23000965
648 (in isoform 2)	Ubiquitination	-	22.81	-
718	Ubiquitination	ACLELKFNQIKAELA HHHHHHHHHHHHHHH	40.87	29967540
721	Ubiquitination	ELKFNQIKAELAKTK HHHHHHHHHHHHHHH	26.50	29967540
727	Phosphorylation	IKAELAKTKGELIKT HHHHHHHHHHHHHHC	38.38	30266825
727	Ubiquitination	IKAELAKTKGELIKT HHHHHHHHHHHHHHC	38.38	21890473
727 (in isoform 3)	Ubiquitination	-	38.38	21890473
736	Ubiquitination	GELIKTKEELKKREN HHHHHCHHHHHHHCC	74.02	29967540
745	Phosphorylation	LKKRENESDSLIQEL HHHHCCCCHHHHHHH	44.04	28450419
747	Phosphorylation	KRENESDSLIQELET HHCCCCHHHHHHHHH	36.33	28450419
747	Ubiquitination	KRENESDSLIQELET HHCCCCHHHHHHHHH	36.33	29967540
758	Ubiquitination	ELETSNKKIITQNQR HHHHCCCHHCCHHHH	43.52	29967540
767	Ubiquitination	ITQNQRIKELINIID CCHHHHHHHHHHHHH	48.97	21890473
767	Ubiquitination	ITQNQRIKELINIID CCHHHHHHHHHHHHH	48.97	22817900
767 (in isoform 1)	Ubiquitination	-	48.97	21890473
767 (in isoform 2)	Ubiquitination	-	48.97	21890473
767 (in isoform 4)	Ubiquitination	-	48.97	21890473
776	Ubiquitination	LINIIDQKEDTINEF HHHHHHCCCCHHHHH	54.53	29967540
779	Phosphorylation	IIDQKEDTINEFQNL HHHCCCCHHHHHHHH	27.13	23403867
787	Ubiquitination	INEFQNLKSHMENTF HHHHHHHHHHHHHCC	45.95	29967540
854	Phosphorylation	KKGSIHVSSAITEDQ CCCCEEEECCCCCCH	10.41	-
858	Phosphorylation	IHVSSAITEDQKKSE EEEECCCCCCHHHCC	32.97	-
864	Phosphorylation	ITEDQKKSEEVRPNI CCCCHHHCCCCCCCC	46.13	-
938	Phosphorylation	KEVQQIQSNYDIAIA HHHHHHHHHHHHEEE	38.70	19835603
940	Phosphorylation	VQQIQSNYDIAIAEL HHHHHHHHHHEEEEH	17.61	19835603
943	Ubiquitination	IQSNYDIAIAELHVQ HHHHHHHEEEEHHHH	7.64	21890473
943 (in isoform 3)	Ubiquitination	-	7.64	21890473
948	Ubiquitination	DIAIAELHVQKSKNQ HHEEEEHHHHHCCCH	16.09	29967540
959 (in isoform 3)	Phosphorylation	-	47.80	-
965	Phosphorylation	EEKIMKLSNEIETAT HHHHHHHHHHHHHHH	27.22	29978859
970	Phosphorylation	KLSNEIETATRSITN HHHHHHHHHHHHHHC	38.70	29978859
972	Phosphorylation	SNEIETATRSITNNV HHHHHHHHHHHHCCH	32.16	29978859
974	Phosphorylation	EIETATRSITNNVSQ HHHHHHHHHHCCHHH	29.43	29978859
976	Phosphorylation	ETATRSITNNVSQIK HHHHHHHHCCHHHHH	23.22	29978859
980	Phosphorylation	RSITNNVSQIKLMHT HHHHCCHHHHHCCCC	28.45	29978859
983	Ubiquitination	TNNVSQIKLMHTKID HCCHHHHHCCCCCHH	31.92	21890473
983	Ubiquitination	TNNVSQIKLMHTKID HCCHHHHHCCCCCHH	31.92	21890473
983 (in isoform 4)	Ubiquitination	-	31.92	21890473
987	Phosphorylation	SQIKLMHTKIDELRT HHHHCCCCCHHHHHC	18.74	29978859
988	Ubiquitination	QIKLMHTKIDELRTL HHHCCCCCHHHHHCC	33.22	29967540
997	Phosphorylation	DELRTLDSVSQISNI HHHHCCCCHHHCCCC	27.12	-
997	Ubiquitination	DELRTLDSVSQISNI HHHHCCCCHHHCCCC	27.12	29967540
999	Phosphorylation	LRTLDSVSQISNIDL HHCCCCHHHCCCCCC	26.25	17525332
1013	Phosphorylation	LLNLRDLSNGSEEDN CCCHHHCCCCCCCCC	43.35	28387310
1013 (in isoform 1)	Ubiquitination	-	43.35	21890473
1016	Phosphorylation	LRDLSNGSEEDNLPN HHHCCCCCCCCCCCC	41.90	28387310
1016 (in isoform 2)	Ubiquitination	-	41.90	21890473
1031 (in isoform 3)	Phosphorylation	-	34.42	-
1032 (in isoform 3)	Phosphorylation	-	36.02	-
1034	Ubiquitination	DLLGNDYLVSKQVKE HHHCCHHHHCHHHHH	3.80	29967540
1037	Ubiquitination	GNDYLVSKQVKEYRI CCHHHHCHHHHHHCC	52.19	29967540
1071	Phosphorylation	CKEIVKASSKKSHQI HHHHHHHCCCCHHHH	36.65	17924679
1072	Phosphorylation	KEIVKASSKKSHQIE HHHHHHCCCCHHHHH	49.30	17924679
1074	Ubiquitination	IVKASSKKSHQIEEL HHHHCCCCHHHHHHH	55.93	29967540
1085	Ubiquitination	IEELEQQIEKLQAEV HHHHHHHHHHHHHHH	5.15	29967540
1125	Ubiquitination	ETLIQQLKEELQEKN HHHHHHHHHHHHHCC	44.82	29967540
1150	Ubiquitination	VEGKRALSELTQGVT HHHHHHHHHHHCCCE	29.58	29967540
1162	Ubiquitination	GVTCYKAKIKELETI CCEEEEHHHHHHHHH	50.59	21890473
1162 (in isoform 3)	Ubiquitination	-	50.59	21890473
1190	Ubiquitination	LEQDILEKESIILKL CCHHHHHHHHHHHHH	54.00	33845483
1202	Ubiquitination	LKLERNLKEFQEHLQ HHHHHHHHHHHHHHH	61.09	21890473
1202	Ubiquitination	LKLERNLKEFQEHLQ HHHHHHHHHHHHHHH	61.09	21890473
1202 (in isoform 4)	Ubiquitination	-	61.09	21890473
1221	Ubiquitination	NTKDLNVKELKLKEE CCCCCCHHHHHHHHH	57.14	33845483
1232 (in isoform 1)	Ubiquitination	-	4.07	21890473
1235 (in isoform 2)	Ubiquitination	-	33.57	21890473
1261	Ubiquitination	RQETEKLKEELSASS HHHHHHHHHHHHHHH	61.28	33845483
1285	Phosphorylation	LQRKEEDYADLKEKL HHHHHHHHHHHHHHH	12.80	29083192
1293	Phosphorylation	ADLKEKLTDAKKQIK HHHHHHHHHHHHHHH	45.00	29083192
1305	Ubiquitination	QIKQVQKEVSVMRDE HHHHHHHHHHHCCCH	23.96	21890473
1305 (in isoform 3)	Ubiquitination	-	23.96	21890473
1307	Phosphorylation	KQVQKEVSVMRDEDK HHHHHHHHHCCCHHH	15.99	27067055
1312	Ubiquitination	EVSVMRDEDKLLRIK HHHHCCCHHHHHHHH	46.83	29967540
1345	Ubiquitination	QRTIQQLKEQLNNQK HHHHHHHHHHHHHHH	38.79	21890473
1345	Ubiquitination	QRTIQQLKEQLNNQK HHHHHHHHHHHHHHH	38.79	29967540
1345 (in isoform 4)	Ubiquitination	-	38.79	21890473
1352	Ubiquitination	KEQLNNQKVEEAIQQ HHHHHHHHHHHHHHH	54.46	29967540
1375 (in isoform 1)	Ubiquitination	-	49.59	21890473
1378 (in isoform 2)	Ubiquitination	-	27.53	21890473
1414	Ubiquitination	TELEKWKEKCNDLET HHHHHHHHHHHHHHH	62.82	29967540
1420	Ubiquitination	KEKCNDLETKNNQRS HHHHHHHHHHCCHHC	61.68	22505724
1421	Ubiquitination	EKCNDLETKNNQRSN HHHHHHHHHCCHHCC	46.50	22505724
1454	Ubiquitination	ELQESEQKYNADRKK HHHHHHHHHCHHHHH	36.10	29967540
1460	Ubiquitination	QKYNADRKKWLEEKM HHHCHHHHHHHHHHH	49.18	22505724
1461	Ubiquitination	KYNADRKKWLEEKMM HHCHHHHHHHHHHHH	58.88	22505724
1471	Phosphorylation	EEKMMLITQAKEAEN HHHHHHHHHHHHHHH	20.65	21406692
1493 (in isoform 2)	Ubiquitination	-	43.10	-
1494 (in isoform 2)	Ubiquitination	-	8.43	-
1504 (in isoform 2)	Phosphorylation	-	1.75	21406692
1505	Phosphorylation	QNEMEILTAQLTEKD HHHHHHHHHHHHHCC	20.30	29083192
1509	Phosphorylation	EILTAQLTEKDSDLQ HHHHHHHHHCCHHHH	28.98	29083192
1511	Ubiquitination	LTAQLTEKDSDLQKW HHHHHHHCCHHHHHH	58.24	29967540
1513	Phosphorylation	AQLTEKDSDLQKWRE HHHHHCCHHHHHHHH	51.82	29083192
1533 (in isoform 3)	Phosphorylation	-	4.27	24719451
1548 (in isoform 3)	Phosphorylation	-	43.62	27251275
1551	Ubiquitination	DNEIEQLKRIISETS CCHHHHHHHHHHHHC	41.04	29967540
1573	Phosphorylation	DIKPKRISSADPDKL CCCCCCCCCCCCCCC	24.41	27422710
1574	Phosphorylation	IKPKRISSADPDKLQ CCCCCCCCCCCCCCC	34.03	28985074
1582	Phosphorylation	ADPDKLQTEPLSTSF CCCCCCCCCCCCCCE	50.43	29449344
1586	Phosphorylation	KLQTEPLSTSFEISR CCCCCCCCCCEEEEC	32.49	30266825
1587	Phosphorylation	LQTEPLSTSFEISRN CCCCCCCCCEEEECC	45.15	30266825
1588	Phosphorylation	QTEPLSTSFEISRNK CCCCCCCCEEEECCC	19.94	30266825
1588 (in isoform 3)	Phosphorylation	-	19.94	27251275
1592	Phosphorylation	LSTSFEISRNKIEDG CCCCEEEECCCCCCC	23.70	30266825
1603 (in isoform 3)	Phosphorylation	-	3.63	24719451
1604 (in isoform 3)	Phosphorylation	-	39.36	27251275
1605	Phosphorylation	DGSVVLDSCEVSTEN CCCEEEEECEEECCC	14.17	26714015
1618 (in isoform 3)	Phosphorylation	-	10.38	27251275
1628	Phosphorylation	PELEIQFTPLQPNKM CCEEEEECCCCCCCE	13.50	29496963
1638	Acetylation	QPNKMAVKHPGCTTP CCCCEECCCCCCCCC	34.25	25953088
1643	Phosphorylation	AVKHPGCTTPVTVKI ECCCCCCCCCEEEEC	39.80	30266825
1644	Phosphorylation	VKHPGCTTPVTVKIP CCCCCCCCCEEEECC	21.60	30266825
1647	Phosphorylation	PGCTTPVTVKIPKAR CCCCCCEEEECCCHH	19.79	30266825
1658	Phosphorylation	PKARKRKSNEMEEDL CCHHCCCCCHHHHHH	41.89	22617229
1669	Phosphorylation	EEDLVKCENKKNATP HHHHHHCCCCCCCCC	67.38	32142685
1675	Phosphorylation	CENKKNATPRTNLKF CCCCCCCCCCCCCCC	23.77	-
1685	Phosphorylation	TNLKFPISDDRNSSV CCCCCCCCCCCCCCC	33.43	27732954
1690	Phosphorylation	PISDDRNSSVKKEQK CCCCCCCCCCCHHHE	37.08	27732954
1691	Phosphorylation	ISDDRNSSVKKEQKV CCCCCCCCCCHHHEE	41.32	27732954
1691 (in isoform 2)	Phosphorylation	-	41.32	21406692
1700	Phosphorylation	KKEQKVAIRPSSKKT CHHHEEEECCCCCCC	8.14	32142685
1700 (in isoform 3)	Phosphorylation	-	8.14	24719451
1709	Phosphorylation	PSSKKTYSLRSQASI CCCCCCEECHHHHEE	23.65	24719451
1712	Phosphorylation	KKTYSLRSQASIIGV CCCEECHHHHEEEEE	35.08	20860994
1715	Phosphorylation	YSLRSQASIIGVNLA EECHHHHEEEEEECC	13.70	23312004
1716 (in isoform 3)	Phosphorylation	-	3.40	27251275
1723	Phosphorylation	IIGVNLATKKKEGTL EEEEECCCCCCCCCH	46.71	20860994
1724	Acetylation	IGVNLATKKKEGTLQ EEEECCCCCCCCCHH	57.13	25953088
1740	Phosphorylation	FGDFLQHSPSILQSK HHHHHHCCHHHHHHH	13.84	25159151
1742	Phosphorylation	DFLQHSPSILQSKAK HHHHCCHHHHHHHHH	38.66	23927012
1746	Phosphorylation	HSPSILQSKAKKIIE CCHHHHHHHHHHHHH	31.00	24732914
1747	Acetylation	SPSILQSKAKKIIET CHHHHHHHHHHHHHH	51.79	25953088
1747 (in isoform 3)	Phosphorylation	-	51.79	24719451
1754	Phosphorylation	KAKKIIETMSSSKLS HHHHHHHHHCCCHHC	16.37	29514088
1756	Phosphorylation	KKIIETMSSSKLSNV HHHHHHHCCCHHCCC	38.59	23403867
1757	Phosphorylation	KIIETMSSSKLSNVE HHHHHHCCCHHCCCH	22.22	29514088
1758	Phosphorylation	IIETMSSSKLSNVEA HHHHHCCCHHCCCHH	30.24	29514088
1766	O-linked_Glycosylation	KLSNVEASKENVSQP HHCCCHHHHCCCCCC	27.31	30379171
1771	O-linked_Glycosylation	EASKENVSQPKRAKR HHHHCCCCCCHHHHH	52.96	30379171
1781	Phosphorylation	KRAKRKLYTSEISSP HHHHHHHHHCCCCCC	15.97	23401153
1782	Phosphorylation	RAKRKLYTSEISSPI HHHHHHHHCCCCCCC	30.25	23401153
1783	Phosphorylation	AKRKLYTSEISSPID HHHHHHHCCCCCCCC	21.26	23401153
1786	Phosphorylation	KLYTSEISSPIDISG HHHHCCCCCCCCCCC	26.47	23401153
1787	Phosphorylation	LYTSEISSPIDISGQ HHHCCCCCCCCCCCC	31.38	23401153
1792	Phosphorylation	ISSPIDISGQVILMD CCCCCCCCCCEEECC	21.30	23401153

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1644	T	Phosphorylation	Kinase	CDK1	P06493	Uniprot

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of KI20B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of KI20B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PIN1_HUMAN	PIN1	genetic	11470801
CRY1_HUMAN	CRY1	physical	26496610
EF1G_HUMAN	EEF1G	physical	26496610
ACSL3_HUMAN	ACSL3	physical	26496610
ENPL_HUMAN	HSP90B1	physical	26496610
MRCKA_HUMAN	CDC42BPA	physical	26496610
STAG1_HUMAN	STAG1	physical	26496610
KDM2A_HUMAN	KDM2A	physical	26496610
ASTE1_HUMAN	ASTE1	physical	26496610
S38A2_HUMAN	SLC38A2	physical	26496610
IMPCT_HUMAN	IMPACT	physical	26496610
CCD94_HUMAN	CCDC94	physical	26496610
VCIP1_HUMAN	VCPIP1	physical	26496610
CMBL_HUMAN	CMBL	physical	26496610
CA052_HUMAN	C1orf52	physical	26496610

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-488 AND SER-999, ANDMASS SPECTROMETRY.
PubMed: 17525332

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-310; SER-321; SER-323;SER-1071 AND SER-1072, AND MASS SPECTROMETRY.
PubMed: 17924679

"Identification of a novel kinesin-related protein, KRMP1, as a targetfor mitotic peptidyl-prolyl isomerase Pin1.";
Kamimoto T., Zama T., Aoki R., Muro Y., Hagiwara M.;
J. Biol. Chem. 276:37520-37528(2001).
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), SUBCELLULAR LOCATION,INTERACTION WITH PIN1, PHOSPHORYLATION AT THR-1644, AND VARIANTSILE-756; LEU-789 AND ARG-1177.
PubMed: 11470801