dbPTM

CCD94_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CCD94_HUMAN
UniProt AC	Q9BW85
Protein Name	Coiled-coil domain-containing protein 94
Gene Name	CCDC94
Organism	Homo sapiens (Human).
Sequence Length	323
Subcellular Localization
Protein Description
Protein Sequence	MSERKVLNKYYPPDFDPSKIPKLKLPKDRQYVVRLMAPFNMRCKTCGEYIYKGKKFNARKETVQNEVYLGLPIFRFYIKCTRCLAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMKVLENRTKDSKLEMEVLENLQELKDLNQRQAHVDFEAMLRQHRLSEEERRRQQQEEDEQETAALLEEARKRRLLEDSDSEDEAAPSPLQPALRPNPTAILDEAPKPKRKVEVWEQSVGSLGSRPPLSRLVVVKKAKADPDCSNGQPQAAPTPGAPQNRKEANPTPLTPGASSLSQLGAYLDSDDSNGSN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
112	Acetylation	TRNFQAEKLLEEEEK CCCHHHHHHHHHHHH	62.48	25953088

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CCD94_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CCD94_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CCD94_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
JADE1_HUMAN	JADE1	physical	25416956
CEP70_HUMAN	CEP70	physical	25416956
PRP19_HUMAN	PRPF19	physical	26186194
SYF1_HUMAN	XAB2	physical	26186194
GPTC1_HUMAN	GPATCH1	physical	26186194
TRI62_HUMAN	TRIM62	physical	26186194
CRNL1_HUMAN	CRNKL1	physical	26186194
PLRG1_HUMAN	PLRG1	physical	26186194
CDC5L_HUMAN	CDC5L	physical	26186194
WDR83_HUMAN	WDR83	physical	26186194
SETMR_HUMAN	SETMAR	physical	26186194
SPB4_HUMAN	SERPINB4	physical	26186194
SNW1_HUMAN	SNW1	physical	26186194
SPF27_HUMAN	BCAS2	physical	26186194
CCD12_HUMAN	CCDC12	physical	26186194
TYPH_HUMAN	TYMP	physical	26186194
HIF1N_HUMAN	HIF1AN	physical	26186194
ISY1_HUMAN	ISY1	physical	26186194
DHX35_HUMAN	DHX35	physical	26186194
SYF2_HUMAN	SYF2	physical	26186194
AQR_HUMAN	AQR	physical	26186194
CALL3_HUMAN	CALML3	physical	26186194
CALL5_HUMAN	CALML5	physical	26186194
4EBP1_HUMAN	EIF4EBP1	physical	26344197
PLRG1_HUMAN	PLRG1	physical	26344197
PRP19_HUMAN	PRPF19	physical	26344197
SETMR_HUMAN	SETMAR	physical	28514442
TRI62_HUMAN	TRIM62	physical	28514442
PRP19_HUMAN	PRPF19	physical	28514442
SPF27_HUMAN	BCAS2	physical	28514442
GPTC1_HUMAN	GPATCH1	physical	28514442
CDC5L_HUMAN	CDC5L	physical	28514442
SYF2_HUMAN	SYF2	physical	28514442
TYPH_HUMAN	TYMP	physical	28514442
AQR_HUMAN	AQR	physical	28514442
CRNL1_HUMAN	CRNKL1	physical	28514442
SYF1_HUMAN	XAB2	physical	28514442
ISY1_HUMAN	ISY1	physical	28514442
WDR83_HUMAN	WDR83	physical	28514442
SPB4_HUMAN	SERPINB4	physical	28514442
DHX35_HUMAN	DHX35	physical	28514442
HIF1N_HUMAN	HIF1AN	physical	28514442
PLRG1_HUMAN	PLRG1	physical	28514442
CCD12_HUMAN	CCDC12	physical	28514442
CALL5_HUMAN	CALML5	physical	28514442
CALL3_HUMAN	CALML3	physical	28514442
RRP44_HUMAN	DIS3	physical	28514442
PPIE_HUMAN	PPIE	physical	28514442

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CCD94_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-211 AND SER-213, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-211; SER-213 ANDSER-220, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-211 AND SER-213, ANDMASS SPECTROMETRY.	17081983 [Abstract]