| UniProt ID | CFA47_HUMAN | |
|---|---|---|
| UniProt AC | Q6ZTR5 | |
| Protein Name | Cilia- and flagella-associated protein 47 {ECO:0000305} | |
| Gene Name | CFAP47 {ECO:0000312|HGNC:HGNC:26708} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 3187 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MNTQKGSLTINVHRGSLAMSIQRGSLVPRDMDSSGRDMQLRVIPAEVKFLDTMAGRVYRLPITVHNICRWNQKIRFKEPVKPQFKLMLTSLDKELASGLQMTAMVEYHPDKDEDTFDRLLISIENKTTEIPLIGLIPSCQLEIESVVNFGTLVANSKVYSKEITITNHGKAPGIFKAEYHGQLPILIFPTSGIVDAKSSMVIKVDFCADQPRIVDEEAIVILQGQPEMLLSIKAHVVEQIIELLSMSSDRRLECIHFGPVFFGSSKIKHARVYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIALNNLTYIRKIKNIDTTIIISCLPNEGTLQPYQKTVITFCFTPKLMAVGKKDIGPSYRQDYALFLRFESVGSKDGFLRDDDYKTIKSERFQKVELALTGTGLPVLLQFDPGPVLNFKPCFMGERSEIQCIIKNQCELLPVTYHFKKTANFEIDPEKGKITGGGMVDVMCSFVPHQLGVFKVKQMIEIIGLVAEEDLQSLSVKSFHHVYLAFNSICKASTKKVVMKFDPGILPSIRNPTGKFVVKDLAKRKNYAPVAMLQSAMTRTHNHRSCEEPVKDMLLAFPNDRAATIRSKDHHKHFRPIFTKVPRFNYVNHDFAYTTFEKQQKKLHENYYAMYLKYLRSVRLQKKQAERERMYSYDDTDIGLEPGSGLKSPSLSEAEIEEELSSAANSIRANRLLTTRGIASQEEESVRRKVLKGLKSEPSTPQEKHDCSLMLTPKQIHQVIVGPSVLNFGNICVNSPNTHLLHVINMLPMHVLLQLDTDLEELQKTNQFSYVILPTSSTYISMVFDSPTIGKFWKSFTFTVNNVPSGHILVVAVVQPVTLELSSNELVLRPRGFFMKTCFRGTVRLYNRQNCCAQFQWQPVNTGRGIAFSICPAKGTVEAYSSLECEVTWQQGFSSPEEGEFILHVFQGNALKLKCVAHLGRTKVLLLQPRILFSNCPQGLTTWRKAILQNVGQNHAYFKVCSQSLLPIINIIPSQGIVPFGGITVLNISCKPTVAEKFDTRAKVSIRHANVIDLRIGGSAEIADVEINPDVFNFSGAYIGGTQIIPFVIKNKGITRARVEFNLKDFPDFSMDLKDKSEEFKDPAVPYIYSLELEENTSLECSITFSPKEVTVVEFIIQVQINFFESSKLYTKYLSSSPSNPKTVPLIRPCYVQATALQSPLNLSSTKFVFEIPLHEMNPNNKVTKTQNLVLYNITKHHVTWTLDLSNTGKLFKDGTFKFSVLNGILRPNEKYNVSISFCPNRPGTYTADIPMLLNYIPVCYKILHLTGEVKSPELLFDPPFIFFTPVPLDITTVMDINILPQNYFRNSTLCVQIPTVRLLDGEEIHPLSVKFPKGRVIPGSHSGINNKLTCHLSFKSSKPVSFFTNLLFCDDRKNWFSLPVTATAENCILTIYPYMAIHLDKQNIILKNDKDEYLKKTRDGVLPPYQDAKPPSPASIKKTYTTSKFNDAEPAKGNLFIGVEVLPENLHLDESETSEEDHGSLEKEKYEQFLSLEEGTKAHYFFEKVVNAAQTWFSLFGWPEGPHSFSIPETIRRDVYKMQFYSSTSPPQKFSRQNDFSKYNKTIYDVLLHLSGKMPPGINSSQSLPVDNHEKRVIQLHLQHSSLLDFLNAQGGCISHVLPEFLLEPEDYKRWIEIMSSTNTMPVSSCTPKKKCSIVIEMSKFEAWSKRAWTDVFLQIYKVLVLSRVVPYCSNNMPPICVQNTPKVNPCFASSNIYSDSERILLSWMNINYENTRHVIWKNCHKDVIPSERWIVNFDKDLSDGLVFATQLGAYCPFLIESHFINMYTRPKSPEEYLHNCLIIVNTLYEIDFDVEIQATDICDPNPILMLMLCVYMYERLPTYLPKKVVSFECTLHDTVLNKILLKNSSSRNLVYNARIVGRDAADFSLSQKGNVVTISPRNEINVTLKFTSRFIRPAEASLLLISKPKNAVRGITMTFALKGKVLDFKAIDIIKCESPCYQFQEVTVNVKNPFHTAGDFSVILVESSTFVSSPTKLTESRQYPKHDDDMSSSGSDTDQGCSDSPNVLHTSIKSTFIREFFCSMHTVHLGVKGTSSLELRFLPFNMHVRYCVIILSNKKIGQLIYVAEGKGMTPLPSSCLPMNTSSSPVYYSTTREEGPNKKYPVLYLKCKPYQILYVDLKLPMTNEAKEKALAFAAQQQMSSIEYERRLITGTLESSSIRVAIALLGLTKIETLMLFRISKLRKPKTVSYTTEVSLPKYFYIPEKISIPWIPEPQVIKLSKAKASDGSVPLPLQFLPLQSGRYPCKILLKSRYDVRAYYVEGIVNEEQPEAKFEFETPAFEALTQNIPIKNQTNDKWTFQVTIEGEWFYGPVDLHVGPDEIVEYPLTFKPIFECVITGKLILQNEVDGREHIFDIKGVGKKPSALEHITVECQVGNVTQKHITLPHFTNTALTFKVTADLPIVWGNPQITVYPYKEILYLIHVRPWKRGILKGTITFSTTRRCTTRRKHDDYEEDTDQDQALSCLDSITEQSSILDDADTYGNFNNLRFWYNLEIHSTPGPPIEIMEMTCIALDSTCIEIPLSNPKDRGLHLEVQLTSAALNGDNEIILSPLQCTKYIVWYSPATTGYSDESIIFQPEMAEEFWYLLKLTIELPKPTTMPEIQCDLGKHVTQIIPLVNCTHETLKLQVTNSNPENFVLDINRKSQLIISPHSTTELPVLFYPSALGRADHQACINFYCTQFTEWKFYLSGVGLFPQPLDTERITTRIGLQSTIVIPFKNPTMEDVLIDIILTSVEHPRNLVMDHCWDSFIYESSAFRFSSPSEIQGIALPPKGNIDISLLFIPQIMKLHKTMVIIEMTKANGKYWPIDNFDELDIKFKSIVGIDSEEIQAIHWIYPIVGLPQAPPPKSPPVVIQCQSRKRAEEKVEIILNAGFFGFSLTPDLTEVLVIPKRNSHNFCEDPNEIPKIHEFEYEIQFESEAMKSKLESCVALYMIEKSYDIMAKRITFIFNLVFTPKKPLRSHITLKIECVTEGIWKFPIMLIATEPDTDAVIDIEGVGLFKESVFELRLKSQTRNPEPFTAHFLPGSDLEFFVKPQAGELLPFNTNGTLITVGFKPKMYCRKYKATLVIQTEEMYWKYEINGLTPTTVPPKNAKAKIDATHKTHDNMPVRPHNFVRENTKLIRTGVSSTIKGAPLVKNQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 14 | Dimethylation | SLTINVHRGSLAMSI EEEEEECCCCEEEEE | - | ||
| 41 | Dimethylation | SGRDMQLRVIPAEVK CCCCCEEEEECCCCE | - | ||
| 139 | Phosphorylation | LIGLIPSCQLEIESV EEEECCCCCEEEEEE | - | ||
| 139 | Phosphorylation | LIGLIPSCQLEIESV EEEECCCCCEEEEEE | - | ||
| 231 | Phosphorylation | GQPEMLLSIKAHVVE CCHHHHHHHHHHHHH | 24719451 | ||
| 244 | Phosphorylation | VEQIIELLSMSSDRR HHHHHHHHCCCCCCC | - | ||
| 244 | Phosphorylation | VEQIIELLSMSSDRR HHHHHHHHCCCCCCC | - | ||
| 246 | Phosphorylation | QIIELLSMSSDRRLE HHHHHHCCCCCCCEE | - | ||
| 246 | Phosphorylation | QIIELLSMSSDRRLE HHHHHHCCCCCCCEE | - | ||
| 303 | Phosphorylation | GTDIQQRTDIALNNL CCCHHHHHHHHHHCH | - | ||
| 311 | Phosphorylation | DIALNNLTYIRKIKN HHHHHCHHHHEEECC | - | ||
| 312 | Phosphorylation | IALNNLTYIRKIKNI HHHHCHHHHEEECCC | - | ||
| 340 | Phosphorylation | TLQPYQKTVITFCFT CCCCCCCEEEEEEEC | - | ||
| 343 | Phosphorylation | PYQKTVITFCFTPKL CCCCEEEEEEECHHH | - | ||
| 347 | Phosphorylation | TVITFCFTPKLMAVG EEEEEEECHHHHHCC | 24719451 | ||
| 362 | Phosphorylation | KKDIGPSYRQDYALF CCCCCCCCCCCEEEE | - | ||
| 366 | Phosphorylation | GPSYRQDYALFLRFE CCCCCCCEEEEEEEE | - | ||
| 372 | Phosphorylation | DYALFLRFESVGSKD CEEEEEEEEECCCCC | - | ||
| 372 | Phosphorylation | DYALFLRFESVGSKD CEEEEEEEEECCCCC | - | ||
| 435 | Phosphorylation | ERSEIQCIIKNQCEL CCCEEEEEEECCEEE | - | ||
| 435 | Phosphorylation | ERSEIQCIIKNQCEL CCCEEEEEEECCEEE | - | ||
| 440 | Phosphorylation | QCIIKNQCELLPVTY EEEEECCEEEEEEEE | 26074081 | ||
| 440 | Phosphorylation | QCIIKNQCELLPVTY EEEEECCEEEEEEEE | 26074081 | ||
| 444 | Phosphorylation | KNQCELLPVTYHFKK ECCEEEEEEEEEEEC | - | ||
| 444 | Phosphorylation | KNQCELLPVTYHFKK ECCEEEEEEEEEEEC | - | ||
| 503 | Phosphorylation | VAEEDLQSLSVKSFH EEHHHHHHCCCCCHH | 24719451 | ||
| 518 | Phosphorylation | HVYLAFNSICKASTK HHHHHHHHHHHHCCC | - | ||
| 538 | Phosphorylation | FDPGILPSIRNPTGK CCCCCCCCCCCCCCC | 24719451 | ||
| 557 | Phosphorylation | DLAKRKNYAPVAMLQ HHHHCCCCCCHHHHH | - | ||
| 565 | Phosphorylation | APVAMLQSAMTRTHN CCHHHHHHHHHHCCC | - | ||
| 565 | Phosphorylation | APVAMLQSAMTRTHN CCHHHHHHHHHHCCC | 22210691 | ||
| 569 | Phosphorylation | MLQSAMTRTHNHRSC HHHHHHHHCCCCCCC | - | ||
| 569 | Phosphorylation | MLQSAMTRTHNHRSC HHHHHHHHCCCCCCC | - | ||
| 572 | Phosphorylation | SAMTRTHNHRSCEEP HHHHHCCCCCCCCCC | - | ||
| 572 | Phosphorylation | SAMTRTHNHRSCEEP HHHHHCCCCCCCCCC | - | ||
| 618 | Phosphorylation | VPRFNYVNHDFAYTT CCCCCCCCCCCHHHH | - | ||
| 618 | Phosphorylation | VPRFNYVNHDFAYTT CCCCCCCCCCCHHHH | - | ||
| 637 | Phosphorylation | QKKLHENYYAMYLKY HHHHHHHHHHHHHHH | 26657352 | ||
| 638 | Phosphorylation | KKLHENYYAMYLKYL HHHHHHHHHHHHHHH | 26657352 | ||
| 641 | Phosphorylation | HENYYAMYLKYLRSV HHHHHHHHHHHHHHH | 21214269 | ||
| 678 | Phosphorylation | EPGSGLKSPSLSEAE CCCCCCCCCCCCHHH | - | ||
| 680 | Phosphorylation | GSGLKSPSLSEAEIE CCCCCCCCCCHHHHH | - | ||
| 806 | Phosphorylation | SYVILPTSSTYISMV EEEEEECCCCEEEEE | - | ||
| 1136 | Phosphorylation | LECSITFSPKEVTVV EEEEEEECCCEEEEE | 24719451 | ||
| 1299 | Phosphorylation | KILHLTGEVKSPELL HHHHHHCCCCCHHHH | 24719451 | ||
| 1437 | Phosphorylation | LDKQNIILKNDKDEY ECCCCEEEECCHHHH | 25332170 | ||
| 1476 | Phosphorylation | KTYTTSKFNDAEPAK EEEECCCCCCCCCCC | 24719451 | ||
| 1489 | Phosphorylation | AKGNLFIGVEVLPEN CCCCEEEEEEECCCC | 24719451 | ||
| 1491 | Phosphorylation | GNLFIGVEVLPENLH CCEEEEEEECCCCCC | 24719451 | ||
| 1505 | Phosphorylation | HLDESETSEEDHGSL CCCCCCCCCCCCCCC | 24719451 | ||
| 1582 | Phosphorylation | TSPPQKFSRQNDFSK CCCCCCCCCCCCHHH | 29759185 | ||
| 1584 | Phosphorylation | PPQKFSRQNDFSKYN CCCCCCCCCCHHHHH | 29759185 | ||
| 1586 | Phosphorylation | QKFSRQNDFSKYNKT CCCCCCCCHHHHHHH | 29759185 | ||
| 1629 | Phosphorylation | KRVIQLHLQHSSLLD HHEEEHHHCCHHHHH | 24719451 | ||
| 1693 | Phosphorylation | VIEMSKFEAWSKRAW EEEECHHHHHHHHHH | 24719451 | ||
| 1775 (in isoform 4) | Phosphorylation | - | - | ||
| 1784 (in isoform 4) | Phosphorylation | - | 24719451 | ||
| 1789 (in isoform 4) | Phosphorylation | - | 24719451 | ||
| 1999 | Phosphorylation | QEVTVNVKNPFHTAG EEEEEEECCCCCCCC | 24719451 | ||
| 2608 | Phosphorylation | LQCTKYIVWYSPATT CCCCEEEEEECCCCC | - | ||
| 2627 | Phosphorylation | ESIIFQPEMAEEFWY CCCCCCHHHHHHHHH | 27273156 | ||
| 2651 | Phosphorylation | KPTTMPEIQCDLGKH CCCCCCEEEECCCCC | 24532841 | ||
| 2653 | Phosphorylation | TTMPEIQCDLGKHVT CCCCEEEECCCCCHH | 24532841 | ||
| 2723 | Phosphorylation | RADHQACINFYCTQF CCCHHHHHHEEECCC | 25332170 | ||
| 2724 | Phosphorylation | ADHQACINFYCTQFT CCHHHHHHEEECCCC | 25332170 | ||
| 2726 | Phosphorylation | HQACINFYCTQFTEW HHHHHHEEECCCCCE | 25332170 | ||
| 2841 | Phosphorylation | IMKLHKTMVIIEMTK HHHHCCEEEEEEEEC | 22210691 | ||
| 2843 | Phosphorylation | KLHKTMVIIEMTKAN HHCCEEEEEEEECCC | 22210691 | ||
| 2909 | Phosphorylation | IQCQSRKRAEEKVEI EEECCCCCHHHHEEE | 26074081 | ||
| 3034 | Phosphorylation | IMLIATEPDTDAVID EEEEECCCCCCCEEE | - | ||
| 3038 | Phosphorylation | ATEPDTDAVIDIEGV ECCCCCCCEEEEECC | - | ||
| 3041 | Phosphorylation | PDTDAVIDIEGVGLF CCCCCEEEEECCEEC | - | ||
| 3047 | Phosphorylation | IDIEGVGLFKESVFE EEEECCEECCCEEEE | 23911959 | ||
| 3049 | Phosphorylation | IEGVGLFKESVFELR EECCEECCCEEEEEE | 23911959 | ||
| 3050 | Phosphorylation | EGVGLFKESVFELRL ECCEECCCEEEEEEE | 23911959 | ||
| 3082 | Phosphorylation | SDLEFFVKPQAGELL CCCEEEECCCCCCEE | 28509920 | ||
| 3087 | Phosphorylation | FVKPQAGELLPFNTN EECCCCCCEECCCCC | 29083192 | ||
| 3090 | Phosphorylation | PQAGELLPFNTNGTL CCCCCEECCCCCCCE | 29083192 | ||
| 3091 | Phosphorylation | QAGELLPFNTNGTLI CCCCEECCCCCCCEE | 28509920 | ||
| 3092 | Phosphorylation | AGELLPFNTNGTLIT CCCEECCCCCCCEEE | 28509920 | ||
| 3100 | Acetylation | TNGTLITVGFKPKMY CCCCEEEEECCHHHE | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CFA47_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CFA47_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CFA47_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CFA47_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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