ZBT47_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZBT47_HUMAN
• UniProt AC: Q9UFB7
• Protein Name: Zinc finger and BTB domain-containing protein 47
• Gene Name: ZBTB47
• Organism: Homo sapiens (Human).
• Sequence Length: 747
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MGRLNEQRLFQPDLCDVDLVLVPQRSVFPAHKGVLAAYSQFFHSLFTQNKQLQRVELSLEALAPGGLQQILNFIYTSKLLVNAANVHEVLSAASLLQMADIAASCQELLDARSLGPPGPGTVALAQPAASCTPAAPPYYCDIKQEADTPGLPKIYAREGPDPYSVRVEDGAGTAGGTVPATIGPAQPFFKEEKEGGVEEAGGPPASLCKLEGGEELEEELGGSGTYSRREQSQIIVEVNLNNQTLHVSTGPEGKPGAGPSPATVVLGREDGLQRHSDEEEEDDEEEEEEEEEEEGGGSGREEEEEEEGGSQGEEEEEEEDGHSEQEEEEEEEEEEGPSEQDQESSEEEEGEEGEAGGKQGPRGSRSSRADPPPHSHMATRSRENARRRGTPEPEEAGRRGGKRPKPPPGVASASARGPPATDGLGAKVKLEEKQHHPCQKCPRVFNNRWYLEKHMNVTHSRMQICDQCGKRFLLESELLLHRQTDCERNIQCVTCGKAFKKLWSLHEHNKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCNERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPYICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVSHTLAGDGVPAAPGLPPTQPQAHALPLLPGLPQTLPPPPHLPPPPPLFPTTASPGGRMNANN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
190	Sumoylation	GPAQPFFKEEKEGGV CCCCCCCCCHHCCCC	22.62	28112733
223	Phosphorylation	LEEELGGSGTYSRRE HHHHHCCCCCCCCCC	6.19	27251275
390	Phosphorylation	ENARRRGTPEPEEAG HHHHHCCCCCHHHHH		25850435
412	Phosphorylation	KPPPGVASASARGPP CCCCCCCCHHCCCCC		20068231
414	Phosphorylation	PPGVASASARGPPAT CCCCCCHHCCCCCCC		20068231
421	Phosphorylation	SARGPPATDGLGAKV HCCCCCCCCCCCCEE		20068231
450	Phosphorylation	RVFNNRWYLEKHMNV CHHCCCHHHHHHCCC		29083192
458	Phosphorylation	LEKHMNVTHSRMQIC HHHHCCCCHHHHHHH		29083192
460	Phosphorylation	KHMNVTHSRMQICDQ HHCCCCHHHHHHHHH		29083192
515	Phosphorylation	HNKIVHGYAEKKFSC CCCCCCCCCCCCCCC		29496907
530	Phosphorylation	EICEKKFYTMAHVRK EECCCEEEEHHHHHH		20068231
531	Phosphorylation	ICEKKFYTMAHVRKH ECCCEEEEHHHHHHH		20068231
543	Phosphorylation	RKHMVAHTKDMPFTC HHHHHHHCCCCCEEE		29449344
549	Phosphorylation	HTKDMPFTCETCGKS HCCCCCEEECCCCCC		29449344
552	Phosphorylation	DMPFTCETCGKSFKR CCCEEECCCCCCHHH		29449344
556	Phosphorylation	TCETCGKSFKRSMSL EECCCCCCHHHHHEE		29449344
567	Phosphorylation	SMSLKVHSLQHSGEK HHEEEEECCCCCCCC		23186163
571	Phosphorylation	KVHSLQHSGEKPFRC EEECCCCCCCCCEEC		25850435
596	Phosphorylation	YQLRSHMSIHIGHKQ HHHHHCCEEEECCCH		27080861
618	Phosphorylation	KDFNMKQYFDEHMKT CCCCHHHHHHHHHHH		30242111
632	Phosphorylation	THTGEKPYICEICGK HCCCCCCEEEECCCC		-
640	Phosphorylation	ICEICGKSFTSRPNM EEECCCCCCCCCCCH		-
653	Phosphorylation	NMKRHRRTHTGEKPY CHHHCCCCCCCCCCC		21712546
655	Phosphorylation	KRHRRTHTGEKPYPC HHCCCCCCCCCCCCC		29214152

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZBT47_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZBT47_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZBT47_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MTG16_HUMAN	CBFA2T3	physical	20116376

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.