| UniProt ID | SNX7_HUMAN | |
|---|---|---|
| UniProt AC | Q9UNH6 | |
| Protein Name | Sorting nexin-7 | |
| Gene Name | SNX7 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 387 | |
| Subcellular Localization |
Cytoplasmic vesicle membrane Peripheral membrane protein Cytoplasmic side. |
|
| Protein Description | May be involved in several stages of intracellular trafficking.. | |
| Protein Sequence | MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MDMNSFSPMMPT ---CCCCCCCCCCCC | 22.06 | 24043423 | |
| 7 | Phosphorylation | -MDMNSFSPMMPTSP -CCCCCCCCCCCCCC | 16.23 | 24043423 | |
| 8 (in isoform 3) | Phosphorylation | - | 22.53 | 27251275 | |
| 8 | Phosphorylation | MDMNSFSPMMPTSPL CCCCCCCCCCCCCCH | 22.53 | 27251275 | |
| 12 | Phosphorylation | SFSPMMPTSPLSMIN CCCCCCCCCCHHHHH | 25.69 | 24275569 | |
| 13 | Phosphorylation | FSPMMPTSPLSMINQ CCCCCCCCCHHHHHH | 20.27 | 23090842 | |
| 16 | Phosphorylation | MMPTSPLSMINQIKF CCCCCCHHHHHHCCC | 22.47 | 24275569 | |
| 35 | Phosphorylation | DLKDLFITVDEPESH CHHHHEEECCCCCCC | 17.99 | 29255136 | |
| 41 | Phosphorylation | ITVDEPESHVTTIET EECCCCCCCEEEEHH | 33.69 | 29255136 | |
| 44 | Phosphorylation | DEPESHVTTIETFIT CCCCCCEEEEHHEEE | 19.34 | 29255136 | |
| 45 | Phosphorylation | EPESHVTTIETFITY CCCCCEEEEHHEEEE | 18.74 | 29255136 | |
| 48 | Phosphorylation | SHVTTIETFITYRII CCEEEEHHEEEEEEE | 19.25 | 29255136 | |
| 51 | Phosphorylation | TTIETFITYRIITKT EEEHHEEEEEEEECC | 11.53 | 29255136 | |
| 52 | Phosphorylation | TIETFITYRIITKTS EEHHEEEEEEEECCC | 8.59 | 29255136 | |
| 56 | Phosphorylation | FITYRIITKTSRGEF EEEEEEEECCCCCCC | 26.37 | 29255136 | |
| 63 (in isoform 3) | Phosphorylation | - | 14.21 | 23090842 | |
| 69 (in isoform 3) | Phosphorylation | - | 30.94 | 23090842 | |
| 71 (in isoform 3) | Phosphorylation | - | 15.34 | 22199227 | |
| 76 (in isoform 3) | Phosphorylation | - | 31.50 | 22199227 | |
| 77 | Phosphorylation | VRRRYQDFLWLKGKL HHHHHHHHHHHHCCH | 2.88 | 27251275 | |
| 77 (in isoform 3) | Phosphorylation | - | 2.88 | 22199227 | |
| 80 (in isoform 3) | Phosphorylation | - | 5.96 | 22199227 | |
| 81 | Methylation | YQDFLWLKGKLEEAH HHHHHHHHCCHHCCC | 42.28 | 115980731 | |
| 83 | Methylation | DFLWLKGKLEEAHPT HHHHHHCCHHCCCCC | 51.65 | 115980737 | |
| 145 | Methylation | EDFKIFLTAQAWELS CCCEEEEEEHHHHHH | 13.13 | - | |
| 147 | Methylation | FKIFLTAQAWELSSH CEEEEEEHHHHHHCC | 41.60 | - | |
| 163 | Ubiquitination | KQGPGLLSRMGQTVR CCCCCHHHHCHHHHH | 25.84 | - | |
| 167 | Ubiquitination | GLLSRMGQTVRAVAS CHHHHCHHHHHHHHH | 27.72 | - | |
| 168 | Phosphorylation | LLSRMGQTVRAVASS HHHHCHHHHHHHHHH | 13.26 | - | |
| 187 | Ubiquitination | KNRPEEFMEMNNFIE CCCHHHHHHHHHHHH | 5.59 | - | |
| 303 | Phosphorylation | DSKVEVLTYKKADTD HHCEEEEEEECCCCC | 38.17 | - | |
| 369 | Ubiquitination | QCLATWESFLTSQTN HHHHHHHHHHHHHHC | 19.67 | - | |
| 370 | Ubiquitination | CLATWESFLTSQTNL HHHHHHHHHHHHHCC | 6.14 | - | |
| 382 | Ubiquitination | TNLHLEEASEDKP-- HCCCHHHHCCCCC-- | 14.62 | - | |
| 386 | Ubiquitination | LEEASEDKP------ HHHHCCCCC------ | 48.88 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SNX7_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SNX7_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SNX7_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| TEX11_HUMAN | TEX11 | physical | 16189514 | |
| TEX11_HUMAN | TEX11 | physical | 25416956 | |
| ASPM_HUMAN | ASPM | physical | 26186194 | |
| SNX4_HUMAN | SNX4 | physical | 26186194 | |
| DTBP1_HUMAN | DTNBP1 | physical | 26186194 | |
| BL1S2_HUMAN | BLOC1S2 | physical | 26186194 | |
| SNX4_HUMAN | SNX4 | physical | 28514442 | |
| DTBP1_HUMAN | DTNBP1 | physical | 28514442 | |
| BL1S2_HUMAN | BLOC1S2 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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