CIA30_HUMAN - dbPTM
CIA30_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CIA30_HUMAN
UniProt AC Q9Y375
Protein Name Complex I intermediate-associated protein 30, mitochondrial
Gene Name NDUFAF1
Organism Homo sapiens (Human).
Sequence Length 327
Subcellular Localization Mitochondrion.
Protein Description Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I)..
Protein Sequence MALVHKLLRGTYFLRKFSKPTSALYPFLGIRFAEYSSSLQKPVASPGKASSQRKTEGDLQGDHQKEVALDITSSEEKPDVSFDKAIRDEAIYHFRLLKDEIVDHWRGPEGHPLHEVLLEQAKVVWQFRGKEDLDKWTVTSDKTIGGRSEVFLKMGKNNQSALLYGTLSSEAPQDGESTRSGYCAMISRIPRGAFERKMSYDWSQFNTLYLRVRGDGRPWMVNIKEDTDFFQRTNQMYSYFMFTRGGPYWQEVKIPFSKFFFSNRGRIRDVQHELPLDKISSIGFTLADKVDGPFFLEIDFIGVFTDPAHTEEFAYENSPELNPRLFK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
45PhosphorylationSLQKPVASPGKASSQ
HCCCCCCCCCCCCCC		34.1329514088
74PhosphorylationVALDITSSEEKPDVS
EEEECCCCCCCCCCC		40.92-
92PhosphorylationAIRDEAIYHFRLLKD
HHCCHHHHHHEEHHH		11.2728064214
153AcetylationGRSEVFLKMGKNNQS
CEEEEEEEECCCCCE		33.8625953088
187PhosphorylationSGYCAMISRIPRGAF
CCEEEEEECCCCCCC		15.8622985185
199PhosphorylationGAFERKMSYDWSQFN
CCCCCCCCCCHHHCC		23.9925219547
200PhosphorylationAFERKMSYDWSQFNT
CCCCCCCCCHHHCCE		20.2425219547
203PhosphorylationRKMSYDWSQFNTLYL
CCCCCCHHHCCEEEE		23.2325219547
207PhosphorylationYDWSQFNTLYLRVRG
CCHHHCCEEEEEECC		20.3325219547
209PhosphorylationWSQFNTLYLRVRGDG
HHHCCEEEEEECCCC		7.1625219547
243PhosphorylationMYSYFMFTRGGPYWQ
HHHEEEEECCCCCCE		19.33-
315PhosphorylationAHTEEFAYENSPELN
HHCHHHHHCCCCCCC		22.4424275569
318PhosphorylationEEFAYENSPELNPRL
HHHHHCCCCCCCCCC		14.0711935339
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CIA30_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CIA30_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CIA30_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ECSIT_HUMANECSITphysical
17344420
ECSIT_HUMANECSITphysical
24344204
ACAD9_HUMANACAD9physical
24344204
T126B_HUMANTMEM126Bphysical
24344204
PININ_HUMANPNNphysical
24344204
NDUF3_HUMANNDUFAF3physical
24344204
STK26_HUMANSTK26physical
24344204
RM01_HUMANMRPL1physical
24344204
ATD3B_HUMANATAD3Bphysical
24344204
NDUBB_HUMANNDUFB11physical
24344204
NDUS1_HUMANNDUFS1physical
24344204
NDUAC_HUMANNDUFA12physical
24344204
TIDC1_HUMANTIMMDC1physical
24344204
NDUS3_HUMANNDUFS3physical
24344204
ACAD9_HUMANACAD9physical
20816094
ECSIT_HUMANECSITphysical
20816094
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CIA30_HUMAN

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Related Literatures of Post-Translational Modification

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