RM01_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM01_HUMAN
• UniProt AC: Q9BYD6
• Protein Name: 39S ribosomal protein L1, mitochondrial
• Gene Name: MRPL1
• Organism: Homo sapiens (Human).
• Sequence Length: 325
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAAAVRCMGRALIHHQRHSLSKMVYQTSLCSCSVNIRVPNRHFAAATKSAKKTKKGAKEKTPDEKKDEIEKIKAYPYMEGEPEDDVYLKRLYPRQIYEVEKAVHLLKKFQILDFTSPKQSVYLDLTLDMALGKKKNVEPFTSVLSLPYPFASEINKVAVFTENASEVKIAEENGAAFAGGTSLIQKIWDDEIVADFYVAVPEIMPELNRLRKKLNKKYPKLSRNSIGRDIPKMLELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRAFLRSSTSEGLLLKIDPLLPKEVKNEESEKEDA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
25	Phosphorylation	HSLSKMVYQTSLCSC HCHHHHHHHHCCCCE	11.54	27732954
27	Phosphorylation	LSKMVYQTSLCSCSV HHHHHHHHCCCCEEE	13.13	27732954
28	Phosphorylation	SKMVYQTSLCSCSVN HHHHHHHCCCCEEEE	16.32	27732954
31	Phosphorylation	VYQTSLCSCSVNIRV HHHHCCCCEEEEEEC	18.08	27732954
53	Phosphorylation	ATKSAKKTKKGAKEK HCCCCHHCCCCCCCC	36.96	-
61	Phosphorylation	KKGAKEKTPDEKKDE CCCCCCCCCCHHHHH	36.74	-
87	Phosphorylation	GEPEDDVYLKRLYPR CCCCCCCHHHHHCHH	17.32	-
107	Ubiquitination	EKAVHLLKKFQILDF HHHHHHHHHCCCCCC	58.88	22817900
108	Ubiquitination	KAVHLLKKFQILDFT HHHHHHHHCCCCCCC	42.33	21890473
108	Acetylation	KAVHLLKKFQILDFT HHHHHHHHCCCCCCC	42.33	25953088
116	Phosphorylation	FQILDFTSPKQSVYL CCCCCCCCCCCEEEE	30.05	28555341
141	Phosphorylation	KKNVEPFTSVLSLPY CCCCCCCCCHHHCCC	28.74	-
161	Phosphorylation	INKVAVFTENASEVK CCEEEEEECCHHCCE	23.02	-
181	Phosphorylation	GAAFAGGTSLIQKIW CCCCCCCCCHHHHHC	21.31	21406692
182	Phosphorylation	AAFAGGTSLIQKIWD CCCCCCCCHHHHHCC	27.10	21406692
216	Ubiquitination	RLRKKLNKKYPKLSR HHHHHHHHHCCCCCC	65.21	24816145
297	Phosphorylation	VVRAFLRSSTSEGLL HHHHHHCCCCCCCEE	39.86	28348404
298	Phosphorylation	VRAFLRSSTSEGLLL HHHHHCCCCCCCEEE	29.53	28348404
299	Phosphorylation	RAFLRSSTSEGLLLK HHHHCCCCCCCEEEE	31.85	28348404
300	Phosphorylation	AFLRSSTSEGLLLKI HHHCCCCCCCEEEEE	31.45	28348404
320	Phosphorylation	KEVKNEESEKEDA-- HHHCCCHHHHCCC--	48.03	23401153

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM01_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM01_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM01_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RT07_HUMAN	MRPS7	physical	22939629
RM10_HUMAN	MRPL10	physical	22939629
RM11_HUMAN	MRPL11	physical	22939629
RM04_HUMAN	MRPL4	physical	22939629
RM12_HUMAN	MRPL12	physical	22939629
VATH_HUMAN	ATP6V1H	physical	26344197
COR1B_HUMAN	CORO1B	physical	26344197
RL12_HUMAN	RPL12	physical	26344197
SETD4_HUMAN	SETD4	physical	26344197
APBB2_HUMAN	APBB2	physical	26496610
RM49_HUMAN	MRPL49	physical	26496610
DIC_HUMAN	SLC25A10	physical	26496610
ICT1_HUMAN	ICT1	physical	26496610
RM12_HUMAN	MRPL12	physical	26496610
LA_HUMAN	SSB	physical	26496610
IRS2_HUMAN	IRS2	physical	26496610
PTTG1_HUMAN	PTTG1	physical	26496610
RM33_HUMAN	MRPL33	physical	26496610
RM19_HUMAN	MRPL19	physical	26496610
RM03_HUMAN	MRPL3	physical	26496610
RM42_HUMAN	MRPL42	physical	26496610
RM13_HUMAN	MRPL13	physical	26496610
RM18_HUMAN	MRPL18	physical	26496610
RM15_HUMAN	MRPL15	physical	26496610
RM02_HUMAN	MRPL2	physical	26496610
RM37_HUMAN	MRPL37	physical	26496610
RM30_HUMAN	MRPL30	physical	26496610
RM35_HUMAN	MRPL35	physical	26496610
RM39_HUMAN	MRPL39	physical	26496610
RM50_HUMAN	MRPL50	physical	26496610
RM16_HUMAN	MRPL16	physical	26496610
PAR16_HUMAN	PARP16	physical	26496610
RM20_HUMAN	MRPL20	physical	26496610
RT18A_HUMAN	MRPS18A	physical	26496610
PR40A_HUMAN	PRPF40A	physical	26496610
NCK5L_HUMAN	NCKAP5L	physical	26496610
RM17_HUMAN	MRPL17	physical	26496610
RM14_HUMAN	MRPL14	physical	26496610
RM40_HUMAN	MRPL40	physical	26496610
RM38_HUMAN	MRPL38	physical	26496610
RM34_HUMAN	MRPL34	physical	26496610
RM32_HUMAN	MRPL32	physical	26496610
RM09_HUMAN	MRPL9	physical	26496610
RM44_HUMAN	MRPL44	physical	26496610
RT63_HUMAN	MRPL57	physical	26496610
BRCC3_HUMAN	BRCC3	physical	26496610
RM43_HUMAN	MRPL43	physical	26496610
G45IP_HUMAN	GADD45GIP1	physical	26496610
RM53_HUMAN	MRPL53	physical	26496610
RM52_HUMAN	MRPL52	physical	26496610
RM10_HUMAN	MRPL10	physical	26496610
ZNT7_HUMAN	SLC30A7	physical	26496610
RM21_HUMAN	MRPL21	physical	26496610

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.