RT18A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RT18A_HUMAN
• UniProt AC: Q9NVS2
• Protein Name: 39S ribosomal protein S18a, mitochondrial
• Gene Name: MRPS18A
• Organism: Homo sapiens (Human).
• Sequence Length: 196
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAALKALVSGCGRLLRGLLAGPAATSWSRLPARGFREVVETQEGKTTIIEGRITATPKESPNPPNPSGQCPICRWNLKHKYNYDDVLLLSQFIRPHGGMLPRKITGLCQEEHRKIEECVKMAHRAGLLPNHRPRLPEGVVPKSKPQLNRYLTRWAPGSVKPIYKKGPRWNRVRMPVGSPLLRDNVCYSRTPWKLYH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
45	Ubiquitination	VVETQEGKTTIIEGR EEECCCCCEEEEECE	41.56	24816145
54	Phosphorylation	TIIEGRITATPKESP EEEECEEEECCCCCC	24.10	27251275
56	Phosphorylation	IEGRITATPKESPNP EECEEEECCCCCCCC	26.66	27251275
108	S-palmitoylation	PRKITGLCQEEHRKI CHHHHHHCHHHHHHH	5.18	21044946
114	Ubiquitination	LCQEEHRKIEECVKM HCHHHHHHHHHHHHH	57.27	24816145
142	Ubiquitination	LPEGVVPKSKPQLNR CCCCCCCCCCHHHHH	60.55	24816145
150 (in isoform 2)	Phosphorylation	-	16.02	20873877
178	Phosphorylation	RVRMPVGSPLLRDNV CEECCCCCCCCCCCC	16.77	24719451
216	Ubiquitination	--------------------------- ---------------------------		24816145

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RT18A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RT18A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RT18A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RM39_HUMAN	MRPL39	physical	26186194
RM47_HUMAN	MRPL47	physical	26186194
ROA1_HUMAN	HNRNPA1	physical	26186194
RT30_HUMAN	MRPS30	physical	26186194
RM47_HUMAN	MRPL47	physical	28514442
RT30_HUMAN	MRPS30	physical	28514442
RM39_HUMAN	MRPL39	physical	28514442
RM41_HUMAN	MRPL41	physical	28514442
ROA1_HUMAN	HNRNPA1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.